Submissions from 2013
Sequential Proteolytic Processing of the Triggering Receptor Expressed on Myeloid Cells-2 (TREM2) Protein by Ectodomain Shedding and γ-Secretase-dependent Intramembranous Cleavage, P Wunderlich, K Glebov, N Kemmerling, NT Tien, H Neumann, and J Walter
Simulation and assessment of dental extraction proficiency Type of project : Self Administered Postal Questionnaire, D. R. Moles, Nigel Honey, and Tom Gale
Sudden unexpected death in epilepsy (SUDEP): Development of a safety checklist, Rohit Shankar, David Cox, Virupakshi Jalihal, Scott Brown, Jane Hanna, and Brendan McLean
The effectiveness and cost-effectiveness of shared care: protocol for realist review, R Hardwick, M Pearson, R Anderson, and R Byng
Trust in the health-care provider-patient relationship: a systematic mapping review of the evidence base., Rebecca Barnes, Nicola Brennan, Mike Calnan, Oonagh Corrigan, Paul Dieppe, and Vikki Entwistle
Δ9-TETRAHYDROCANNABINOL IS PROTECTIVE THROUGH PPARγ DEPENDENT MITOCHONDRIAL BIOGENESIS IN A CELL CULTURE MODEL OF PARKINSON'S DISEASE., ML Zeissler, J Eastwood, Hanemann C Oliver, J Zajicek, and C Carroll
Submissions from 2012
Neuropsychological outcomes in adults commencing highly active anti-retroviral treatment in South Africa: a prospective study, JA Joska, J Westgarth-Taylor, J Hoare, KGF Thomas, and et al
Enamel Defects in Carriers of a Novel LAMA3 Mutation Underlying Epidermolysis Bullosa, WY Yuen, AM Pasmooij, C Stellingsma, and MF Jonkman
Neutralizing Antibodies and Pathogenesis of Hepatitis C Virus Infection, Samira Fafi-Kremer, Catherine Fauvelle, Daniel J. Felmlee, Mirjam B. Zeisel, Quentin Lepiller, Isabel Fofana, Laura Heydmann, Françoise Stoll-Keller, and Thomas F. Baumert
A new taxonomy for describing and defining adherence to medications, B Vrijens, S De Geest, DA Hughes, K Przemyslaw, and et al
Being young in Cornwall, J Baceva and JF Tredinnick-Rowe
Effectiveness of a gentamicin impregnated collagen sponge on reducing sternal wound infections following cardiac surgery: a meta-analysis of randomised controlled trials, S Creanor, A Barton, and A Marchbank
A longitudinal study of the effect of Antarctic residence on energy dynamics and aerobic fitness, A Simpson and V Maynard
Age before stage: insulin resistance rises before the onset of puberty: a 9-year longitudinal study (EarlyBird 26)., AN Jeffery, BS Metcalf, J Hosking, AJ Streeter, LD Voss, and TJ Wilkin
Analysis and validation of a Parkinson's disease register as a recruitment tool for clinical studies., Camille Carroll, Amy Palmer, Christine Cosby, and John Zajicek
Control of interneuron dendritic growth through NRG1/erbB4-mediated kalirin-7 disinhibition., P. Penzes, M. E. Cahill, K. A. Jones, I. Rafalovich, Z. Xie, C. S. Barros, and U. Müller
Facilitated physical activity as a treatment for depressed adults: randomised controlled trial, Melanie Chalder, Nicola J. Wiles, John Campbell, Sandra P. Hollinghurst, Anne M. Haase, Adrian H. Taylor, Kenneth R. Fox, Ceire Costelloe, Aidan Searle, Helen Baxter, Rachel Winder, Christine Wright, Katrina M. Turner, Michael Calnan, Deborah A. Lawlor, Tim J. Peters, Deborah J. Sharp, Alan A. Montgomery, and Glyn Lewis
Guided self-help concreteness training as an intervention for major depression in primary care: a Phase II randomized controlled trial., E. R. Watkins, R. S. Taylor, R. Byng, C. Baeyens, R. Read, K. Pearson, and L. Watson
Neurofibromatosis 2011: a report of the Children's Tumor Foundation annual meeting., Michel Kalamarides, Maria T. Acosta, Dusica Babovic-Vuksanovic, Olli Carpen, Karen Cichowski, DG Evans, Filippo Giancotti, CO Hanemann, David Ingram, Alison C. Lloyd, Debra A. Mayes, Ludwine Messiaen, Helen Morrison, Kathryn North, Roger Packer, Duojia Pan, Anat Stemmer-Rachamimov, Meena Upadhyaya, David Viskochil, Margret R. Wallace, Kim Hunter-Schaedle, and Nancy Ratner
Physical activity as an aid to smoking cessation during pregnancy (LEAP) trial: study protocol for a randomized controlled trial, Michael Ussher, Paul Aveyard, Isaac Manyonda, S Lewis, Robert West, B Lewis, Bess Marcus, Adrian H. Taylor, Pelham Barton, and Tim Coleman
Producing multimedia resources for teaching medical students about the social context of medicine: a partnership approach, Tracey Collett and Priska Schoenborn
Statins in Unconventional Secretion of Insulin-Degrading Enzyme and Degradation of the Amyloid-β Peptide, K Glebov and J Walter
The role of insulin-like growth factors signaling in merlin-deficient human schwannomas., C. Oliver Hanemann, Sylwia Ammoun, M. Caroline Schmid, Natalia Ristic, Lu Zhou, David Hilton, Emanuela Ercolano, and Camille Carroll
Submissions from 2011
Effect of exercise referral schemes in primary care on physical activity and improving health outcomes: systematic review and meta-analysis., T. G. Pavey, AH Taylor, K. R. Fox, M. Hillsdon, N. Anokye, J. L. Campbell, C. Foster, C. Green, T. Moxham, N. Mutrie, J. Searle, P. Trueman, and RS Taylor
Factors associated with variability in the assessment of UK doctors' professionalism: analysis of survey results, JL Campbell, M Roberts, C Wright, J Hill, and et al
A tool to measure the attributes of receiving IV therapy in a home versus hospital setting: the Multiple Sclerosis Relapse Management Scale (MSRMS)., Jeremy C. Hobart, Afsane Riazi, Bernadette Porter, Jeremy Chataway, and Alan J. Thompson
Protocol for a double-blind randomised placebo-controlled trial of lithium carbonate in patients with amyotrophic Lateral Sclerosis (LiCALS) [Eudract number: 2008-006891-31], Ammar Al-Chalabi, Pamela J. Shaw, Carolyn A. Young, Karen E. Morrison, Caroline Murphy, Marie Thornhill, Joanna Kelly, I. Nicholas Steen, P. Nigel Leigh, and Oliver Hanemann
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis, Peter Donnelly, Stephen Sawcer, Garrett Hellenthal, Matti Pirinen, Chris C.A. Spencer, Nikolaos A. Patsopoulos, Loukas Moutsianas, Alexander Dilthey, Zhan Su, Colin Freeman, Sarah E. Hunt, Sarah Edkins, Emma Gray, David R. Booth, Simon C. Potter, An Goris, Gavin Band, Annette Bang Oturai, Amy Strange, Janna Saarela, Céline Bellenguez, Bertrand Fontaine, Matthew Gillman, Bernhard Hemmer, Rhian Gwilliam, Frauke Zipp, Alagurevathi Jayakumar, Roland Martin, Stephen Leslie, and Stanley Hawkins
NFATc1 affects mouse splenic B cell function by controlling the calcineurin–NFAT signaling network, Edgar Serfling, Sankar Bhattacharyya, Jolly Deb, Amiya K. Patra, Pham DA Thuy, Wen Chen, Martin Vaeth, Friederike Berberich-Siebelt, Stefan Klein-Hessling, Edward D. Lamperti, Kurt Reifenberg, Julia Jellusova, Astrid Schweizer, Lars Nitschke, Ellen Leich, Andreas Rosenwald, Cornelia Brunner, Swen Engelmann, Ursula Bommhardt, Andris Avots, Martin R. Müller, and Eisaku Kondo
Patients' views of physical activity as treatment for depression: a qualitative study, Aidan Searle, Michael Calnan, Glyn Lewis, John Campbell, Adrian Taylor, and Katrina Turner
Changes in iron-regulatory gene expression occur in human cell culture models of Parkinson's disease., C. B. Carroll, M. L. Zeissler, N. Chadborn, K. Gibson, G. Williams, J. P. Zajicek, K. E. Morrison, and C. O. Hanemann
Designing clinical trials in older people., C. B. Carroll and J. P. Zajicek
Exploring the Map of Medicine's potential in undergraduate medical education., Nicola Brennan and Karen Mattick
Management of patient adherence to medications: protocol for an online survey of doctors, pharmacists and nurses in Europe, W Clyne, C Mshelia, S Hall, S McLachlan, and et al
Propofol and children--what we know and what we do not know., AE Rigby-Jones and JR Sneyd
Radiological findings in patients undergoing revision endoscopic sinus surgery: a retrospective case series study, HS Khalil, AZ Eweiss, and N Clifton
The Map of Medicine: a review of evidence for its impact on healthcare., Nicola Brennan, Karen Mattick, and Tricia Ellis
The problem with health measurement., Stefan J. Cano and Jeremy C. Hobart
Women's experience of colposcopy: a qualitative investigation, Dawn R. Swancutt, Sheila M. Greenfield, David M. Luesley, and Sue Wilson
Submissions from 2010
Integrating the promotion of physical activity within a smoking cessation programme: findings from collaborative action research in UK Stop Smoking Services., Adrian H. Taylor, Emma S. Everson-Hock, and Michael Ussher
Study protocol for a randomized controlled trial comparing mindfulness-based cognitive therapy with maintenance anti-depressant treatment in the prevention of depressive relapse/recurrence: the PREVENT trial., Willem Kuyken, Sarah Byford, Richard Byng, Tim Dalgleish, Glyn Lewis, Rod Taylor, Edward R. Watkins, Rachel Hayes, Paul Lanham, David Kessler, Nicola Morant, and Alison Evans
Patient-orientated longitudinal study of multiple sclerosis in south west England (The South West Impact of Multiple Sclerosis Project, SWIMS) 1: protocol and baseline characteristics of cohort., John P. Zajicek, Wendy M. Ingram, Jane Vickery, Siobhan Creanor, Dave E. Wright, and Jeremy C. Hobart
First‐trimester combined screening for trisomy 21 at 7–14 weeks' gestation, D Wright, K Spencer, KK Kagan, N Tørring, and et al
Selecting GLP-1 agonists in the management of type 2 diabetes: differential pharmacology and therapeutic benefits of liraglutide and exenatide., J Pinkney, T Fox, and L Ranganath
ErbB/HER receptor activation and preclinical efficacy of lapatinib in vestibular schwannoma, Sylwia Ammoun, Clare H. Cunliffe, Jeffrey C. Allen, Luis Chiriboga, Filippo G. Giancotti, David Zagzag, C. Oliver Hanemann, and Matthias A. Karajannis
CBD & D9-THC - the two faces of cannabis, Zeissler, CB Carroll, and J Zajicek
Bio-informatics analysis of a gene co-expression module in adipose tissue containing the diet-responsive gene Nnat., X Li.X, PA Thomason, DJ Withers, and J Scott
Cannabinoids Are Neuroprotective in a Human Cell Culture Model of Parkinson's Disease, CB Carroll, ML Zeissler, V Stone, CO Hanemann, and JP Zajicek
Changes in Iron-Regulatory Gene Expression Occur in Human Cell Culture Models of PD, CB Carroll, ML Zeissler, N Chadborn, K Gibson, GJ Williams, KE Morrison, JP Zajicek, and CO Hanemann
Cross-trimester repeated measures testing for Down's syndrome screening: an assessment., D. Wright, I. Bradbury, F. Malone, M. D'Alton, A. Summers, T. Huang, S. Ball, A. Baker, B. Nix, D. Aitken, J. Crossley, H. Cuckle, and K. Spencer
Effects of HIF-1 and HIF2 on Growth and Metabolism of Clear-Cell Renal Cell Carcinoma 786-0 Xenografts, S Biswas, H Troy, R Leek, Y-L Chung, and et al
Endoscopic Resection and Topical 5-Fluorouracil as an Alternative Treatment to Craniofacial Resection for the Management of Primary Intestinal-Type Sinonasal Adenocarcinoma, S Mackie, T Malik, and H Khalil
Impact of workplace based assessment on doctors' education and performance: a systematic review., A Miller and J Archer
Persistent CSF Rhinorrhoea, Pneumocephalus, and Recurrent Meningitis Following Misdiagnosis of Olfactory Neuroblastoma, N Barua, DA Hilton, W Mukonoweshuro, H Khalil, and L Pobereskin
Physical activity as a treatment for depression: the TREAD randomised trial protocol, Helen Baxter, Rachel Winder, Melanie Chalder, Christine Wright, Sofie Sherlock, Anne Haase, Nicola J. Wiles, Alan A. Montgomery, Adrian H. Taylor, Ken R. Fox, Debbie A. Lawlor, Tim J. Peters, Deborah J. Sharp, John Campbell, and Glyn Lewis
The transition from medical student to junior doctor: today's experiences of Tomorrow's Doctors., Nicola Brennan, Oonagh Corrigan, Jon Allard, Julian Archer, Rebecca Barnes, Alan Bleakley, Tracey Collett, and Bere SR de
Submissions from 2009
Role of Hypoxia‐Inducible Factors in Epigenetic Regulation via Histone Demethylases, J Yang, I Ledaki, H Turley, KC Gatter, and et al
Acquired neuromyotonia following upper respiratory tract infection: a case report., I Imam, S Edwards, and CO Hanemann
Aquired neuromyotonia following upper respiratory tract infection, I Imam, S Edwards, and CO Hanemann
Cauda equina syndrome following a lumbar puncture., Alexandra J. Sinclair, Camille Carroll, and Brendan Davies
Chemotherapy related encephalopathy in a patient with Stage IV cervical carcinoma treated with cisplatin and 5-fluorouracil: a case report, AL Chue, IN Fernando, SA Hussain, and DA Yates
Objectively measured physical activity and its association with adiponectin and other novel metabolic markers: a longitudinal study in children (EarlyBird 38)., BS Metcalf, AN Jeffery, J Hosking, LD Voss, N Sattar, and TJ Wilkin
Regulation of the fibrosis and angiogenesis promoter SPARC/osteonectin in human adipose tissue by weight change, leptin, insulin, and glucose., Katrina Kos, Steve Wong, Bee Tan, Anders Gummesson, Margareta Jernas, Niclas Franck, David Kerrigan, Fredrik H. Nystrom, Lena M.S. Carlsson, Harpal S. Randeva, Jonathan H. Pinkney, and John P.H. Wilding
The size of the treatment effect: do patients and proxies agree?, der Linden FAH van, Jolijn J. Kragt, Jeremy C. Hobart, Martin Klein, Alan J. Thompson, der Ploeg HM van, Chris H. Polman, and Bernard M.J. Uitdehaag
Submissions from 2008
Exposing the key functions of a complex intervention for shared care in mental health: case study of a process evaluation., Richard Byng, Ian Norman, Sally Redfern, and Roger Jones
The cervical dystonia impact profile (CDIP-58): can a Rasch developed patient reported outcome measure satisfy traditional psychometric criteria?, Jeremy C. Hobart, Stefan J. Cano, Thomas T. Warner, Alan J. Thompson, Kailash P. Bhatia, and Ray Fitzpatrick
A guide to medication review, W Clyne, A Blenkinsopp, and R Seal
c-Jun is a negative regulator of myelination., David B. Parkinson, Ambily Bhaskaran, Peter Arthur-Farraj, Luke A. Noon, Ashwin Woodhoo, Alison C. Lloyd, M. Laura Feltri, Lawrence Wrabetz, Axel Behrens, Rhona Mirsky, and Kristján R. Jessen
A Genome-Wide Association Study Identifies Protein Quantitative Trait Loci (pQTLs), D Melzer, JRB Perry, D Hernandez, and et al
Surveillance of cirrhosis for hepatocellular carcinoma: a cost-utility analysis., Coon J Thompson, G. Rogers, P. Hewson, D. Wright, R. Anderson, S. Jackson, S. Ryder, M. Cramp, and K. Stein
Beyond the limits of clinical governance? The case of mental health in English primary care, Linda Gask, Anne Rogers, Stephen Campbell, and Rod Sheaff
Women's colposcopy experience and preferences: a mixed methods study., Dawn R. Swancutt, Sheila M. Greenfield, and Sue Wilson
Submissions from 2007
Hypoxia-regulated carbonic anhydrase IX expression is associated with poor survival in patients with invasive breast cancer, SA Hussain, R Ganesan, G Reynolds, L Gross, and et al
The feminisation of British neurology: implications for workforce planning., C. B. Carroll, DSNAP Tengah, C. Lawthom, and G. Venables
Submissions from 2006
Can learning organizations survive in the newer NHS?, Rod Sheaff and David Pilgrim
Sowing date, transplanting, plant density and nitrogen fertilization affect indigo production from Isatis species in a Mediterranean region of Spain, E Sales, R Kanhonou, C Baixauli, A Giner, D Cooke, K Gilbert, I Arrillaga, J Segura, and R Ros
Submissions from 2005
Construction and validation of a Bovine Innate Immune Microarray, L Donaldson, T Vuocolo, C Gray, Y Strandberg, and et al
HCV-specific cellular immune responses in subjects exposed, but uninfected by HCV, MK Metzner, A Houldsworth, A Demaine, E Kaminski, and ME Cramp
HCV-specific cellular immune responses in subjects exposed to but uninfected by HCV, M Metzner, A Houldsworth, AG Demaine, E Kaminski, and ME Cramp
Histopathological changes in the human larynx following expanded polytetrafluroethylene (Gore-Tex®) implantation, K Rajkumar, HS Khalil, M Elloy, E Sheffield, and DL Baldwin
Laughing all the way to the item bank: how to improve your treatment effect by improving your outcome measurement, R Baron and J Hobart
Muscle cramps and weakness secondary to graft versus host disease fasciitis., Camille B. Carroll, D. A. Hilton, M. Hamon, and J. P. Zajicek
Quantifying drug-induced dyskinesias in the arms using digitised spiral-drawing tasks, Xuguang Liu, Camille B. Carroll, Shou Yan Wang, John Zajicek, and Peter G. Bain
Submissions from 2004
Quantitative Analysis of Indigo and Indigo Precursors in Leaves of Isatis spp. and Polygonum tinctorium, KG Gilbert, HG Maule, B Rudolph, M Lewis, and et al
A phase I/II study of gemcitabine and fractionated cisplatin in an outpatient setting using a 21-day schedule in patients with advanced and metastatic bladder cancer, SA Hussain, DD Stocken, P Riley, DH Palmer, and et al
Long-term results of a phase II study of synchronous chemoradiotherapy in advanced muscle invasive bladder cancer, SA Hussain, DD Stocken, DR Peake, JG Glaholm, and et al
A randomised controlled trial and cost effectiveness study of systematic screening (targeted and total population screening) versus routine practice for the detection of atrial fibrillation in the over 65s: (SAFE) [ISRCTN19633732], David Fitzmaurice, Dawn Swancutt, Richard Hobbs, Jonathan Mant, Ellen Murray, Sue Jowett, James Raftery, Stirling Bryan, Michael Davies, and Gregory Lip
Do on-off variations cause discrepancies in the historical items of the UPDRS?, Camille B. Carroll and Peter G. Bain
Krox-20 inhibits Jun-NH2-terminal kinase/c-Jun to control Schwann cell proliferation and death, David B. Parkinson, Ambily Bhaskaran, Sarah Dickinson, and Anna Droggiti
Provision of 24 hour acute neurology care by neurologists: manpower requirements in the UK., C. Carroll and J. Zajicek
Quantitative analysis of indigo and indigo precursors in leaves of Isatis spp. and Polygonum tinctorium., KG Gilbert, HG Maule, B Rudolph, M Lewis, H Vandenburg, E Sales, S Tozzi, and DT Cooke
Raised intracranial pressure presenting with spontaneous periorbital bruising: two case reports, S Hadjikoutis, CB Carroll, and GTP Plant
Stroke in Devon: knowledge was good, but action was poor., C. Carroll, J. Hobart, C. Fox, L. Teare, and J. Gibson
Submissions from 2003
Proapoptotic genes BAX and CD40L are predictors of survival in transitional cell carcinoma of the bladder, SA Hussain, R Ganesan, L Hiller, PG Murray, and et al
A new HPLC-ELSD method to quantify indican in Polygonum tinctorium L. and to evaluate beta-glucosidase hydrolysis of indican for indigo production., LG Angelini, E Campeol, S Tozzi, KG Gilbert, DT Cooke, and P John
A New HPLC‐ELSD Method To Quantify Indican in Polygonum tinctorium L. and To Evaluate β‐Glucosidase Hydrolysis of Indican for Indigo Production, LG Angelini, E Campeol, S Tozzi, and et al
Canal wall down mastoidectomy: A long term commitment to the outpatients?, HS Khalil and PC Windle-Taylor
Complete analysis of the B‐cell response to a protein antigen, from in vivo germinal centre formation to 3‐D modelling of affinity maturation, CL Adams, MKL Macleod, Milner‐White E James, R Aitken, P Garside, and DI Stott
Non-legitimate illness, embodied experience and the moral career: the case of ME/CFS, T Collett