Submissions from 2018
A pilot randomised controlled trial investigating a mindfulness-based stress reduction (MBSR) intervention in individuals with pulmonary arterial hypertension (PAH): the PATHWAYS study, RMR Tulloh, V Garratt, J Tagney, J Turner-Cobb, and et al
Etiology and treatment of Parkinson Disease, E Kramer
Physical activity for antenatal and postnatal depression in women attempting to quit smoking: randomised controlled trial, Amanda Daley, Muhammad Riaz, S Lewis, Paul Aveyard, Tim Coleman, Isaac Manyonda, Robert West, B Lewis, Bess Marcus, Adrian Taylor, Judith Ibison, Andrew Kent, and Michael Ussher
Ultramicroscopy/lightsheet-microscopy in dementia, E Kramer
A systematic review and consensus definitions for standardised end-points in perioperative medicine: pulmonary complications, RM Pearse and StEP-COMPAC Group
Children’s Compliance With Wrist-Worn Accelerometry Within a Cluster-Randomized Controlled Trial: Findings From the Healthy Lifestyles Programme, L Price, K Wyatt, J Lloyd, C Abraham, and et al
Desperately seeking outcomes: quantifying the effectiveness of community mental healthcare using Health of the Nation Outcome Scales, R Laugharne, S Eaves, A Mascas, K Psatha, and et al
Desperately seeking outcomes: Quantifying the effectiveness of community mental healthcare using Health of the Nation Outcome Scales, Richard Laugharne, Scott Eaves, Alin Mascas, Kiki Psatha, Gill Dinnis, Jonathan Trower, and Rohit Shankar
Differential phosphorylation and n-terminal configuration of capsid subunits in parvovirus assembly and viral trafficking, J Gil-Ranedo, E Hernando, N Valle, L Riolobos, B Maroto, and JM Almendral
Evaluating the development of medical revalidation in England and its impact on organisational performance and medical practice: overview report, J Archer, K Bloor, C Bojke, A Boyd, M Bryce, J Ferguson, N Gutacker, C Hillier, K Luscombe, T Price, de Bere S Regan, A Tazzyman, J Tredinnick-Rowe, and K Walshe
‘It's a silver lining’: A template analysis of satisfaction and quality of life following post‐mastectomy breast reconstruction, H Matthews, A Turner, I Williamson, and W Clyne
Mental Health in UK Biobank - development, implementation and results from an online questionnaire completed by 157,366 participants, WE Lee, K Davis, J Coleman, M Adams, and et al
Personal wellbeing networks, social capital and severe mental illness: findings from an exploratory study, Daryl Sweet, Richard Byng, Martin Webber, Doyo Gragn Enki, Ian Porter, John Larsen, Peter Huxley, and Vanessa Pinfold
UMbRELLA: Evaluating the regulatory impacts of medical revalidation – final report., J Archer, N Cameron, M Lewis, M Marshall, J O'Hanlon, de Bere S Regan, K Walshe, R Baines, A Boyd, M Bryce, J Ferguson, E Gabe-Thomas, S Holmes, M Lalani, T Price, P Rae, M Roberts, S Stevens, A Tazzyman, J Tredinnick-Rowe, J Wakeling, and D Zahra
The International Landscape of Medical Licensing Examinations: A Typology Derived From a Systematic Review, Tristan Price, Nick Lynn, Lee Coombes, Martin Roberts, Tom Gale, de Bere S Regan, and Julian Archer
Has the time come to stratify and score SUDEP risk to inform people with epilepsy of their changes in safety?, Rohit Shankar, Craig Newman, Alistair Gales, Brendan N. McLean, Jane Hanna, Samantha Ashby, Matthew C. Walker, and Josemir W. Sander
IMPACT OF DEMENTIA CARE HOME LEARNING COMMUNITY IN DEMENTIA CARE HOMES IN TORBAY, DEVON, UK, A Rana, D Somerfield, and R Sheaff
Ret protects the midbrain dopaminergic system against α- synuclein toxicity., E Kramer
Using Social Media to Generate and Collect Primary Data: The #ShowsWorkplaceCompassion Twitter Research Campaign, W Clyne, S Pezaro, K Deeny, and R Kneafsey
A Case of Invasive Sinonasal Carcinosarcoma: The Importance of Early Detection, J Yuen, V Varadarajan, M Stavrakas, S Muquit, and H Khalil
Moral narratives and mental health: rethinking understandings of distress and healthcare support in contexts of austerity and welfare reform, Felicity Thomas, Lorraine Hansford, Joseph Ford, Katrina Wyatt, Rosemarie McCabe, and Richard Byng
Discrimination, harassment and non-reporting in UK medical education, Jonathan Broad, Marion Matheson, Fabienne Verrall, Anna K. Taylor, Daniel Zahra, Louise Alldridge, and Gene Feder
The Evolving Purposes of Medical Revalidation in the United Kingdom: A Qualitative Study of Professional and Regulatory Narratives, Abigail Tazzyman, Jane Ferguson, Kieran Walshe, Alan Boyd, John Tredinnick-Rowe, Charlotte Hillier, De Bere S Regan, and Julian Archer
Interventions for reducing unplanned paediatric admissions: an observational study in one hospital, Kerryn Husk, Vashti Berry, Richard Tozer, Gina Skipwith, Robert Radmore, Susan Ball, Obioha C. Ukoumunne, and Stuart Logan
Prescribing gardening and conservation activities for health and wellbeing in older people, Kerryn Husk, Rebecca Lovell, and Ruth Garside
Implication of Major Adverse Postoperative Events and Myocardial Injury on Disability and Survival: A Planned Subanalysis of the ENIGMA-II Trial., WS Beattie and et al
The Role of Pedagogy in Clinical Education, J Tredinnick-Rowe
Digital care in epilepsy: A conceptual framework for technological therapies, Rohit Shankar, Rupert Page, Brendan N. McLean, Jane Hanna, and Craig Newman
Video-calls to reduce loneliness and social isolation within care environments for older people: an implementation study using collaborative action research, Sonam Zamir, Catherine Hagan Hennessy, Adrian H. Taylor, and Ray B. Jones
Application of prognostic scores in the STOPAH trial: Discriminant function is no longer the optimal scoring system in alcoholic hepatitis, Ewan H. Forrest, Stephen R. Atkinson, Paul Richardson, Steven Masson, Stephen Ryder, Mark R. Thursz, Michael Allison, Anne McCune, Dermot Gleeson, Andrew Austin, David Patch, Ashwin Dhanda, Debbie Shawcross, and Mark Wright
Association between Household Air Pollution Exposure and Chronic Obstructive Pulmonary Disease Outcomes in 13 Low- and Middle-Income Country Settings., T Siddharthan, MR Grigsby, D Goodman, M Chowdhury, A Rubinstein, V Irazola, L Gutierrez, JJ Miranda, A Bernabe-Ortiz, D Alam, B Kirenga, R Jones, Gemert F van, RA Wise, and W Checkley
Atezolizumab in Platinum-treated Locally Advanced or Metastatic Urothelial Carcinoma: Outcomes by Prior Number of Regimens., JL Perez-Gracia, Y Loriot, JE Rosenberg, T Powles, and et al
Enhanced natural killer cell activity is found in exposed uninfected recipients of hepatitis C-contaminated blood, M. M. Ow, D. Hegazy, U. M. Warshow, and M. E. Cramp
Factors influencing treatment escalation from long-acting muscarinic antagonist monotherapy to triple therapy in patients with COPD: a retrospective THIN-database analysis, JR Hurst, M Dilleen, K Morris, S Hills, B Emir, and R Jones
From Programme Theory to Logic Models for Multispecialty Community Providers: A Realist Evidence Synthesis, WR Sheaff, S Brand, H LLoyd, A Wanner, M Fornasiero, S Briscoe, J Valderas, R Byng, and M Pearson
Insulin resistance is higher in prepubertal girls but switches to become higher in boys at age 16: A Cohort Study (EarlyBird 57), SC Jeffery, Joanne Hosking, AN Jeffery, Michael J. Murphy, Linda D. Voss, Terence J. Wilkin, and Jonathan Pinkney
The 2018 Lake Louise Acute Mountain Sickness Score, Robert C. Roach, Peter H. Hackett, Oswald Oelz, Peter Bärtsch, Andrew M. Luks, Martin J. MacInnis, J. Kenneth Baillie, Eric Achatz, Edi Albert, JS Andrews, JD Anholm, MZ Ashraf, P Auerbach, B Basnyat, BA Beidleman, RR Berendsen, MM Berger, KE Bloch, H Brugger, A Cogo, RG Costa, A Cumpstey, A Cymerman, T Debevec, C Duncan, D Dubowitz, A Fago, M Furian, M Gaidica, P Ganguli, MPW Grocott, D Hammer, D Hall, D Hillebrandt, MP Hilty, G Himashree, B Honigman, N Gilbert-Kawai, B Kayser, L Keyes, M Koehle, S Kohli, A Kuenzel, BD Levine, M Lichtblau, J Macdonald, MB Maeder, M Maggiorini, Daniel Martin, S Masuyama, J McCall, S McIntosh, Gregoire Millet, Fernando Moraga, Craig Mounsey, Stephen R. Muza, Samuel Oliver, Qadar Pasha, Ryan Paterson, Lara Phillips, Aurélien Pichon, Philipp A. Pickerodt, Matiram Pun, Manjari Rain, Drummond Rennie, G Ri-Li, Steven Roy, Samuel Verges, Santos TBC dos, Robert B. Schoene, Otto D. Schoch, Surinderpal Singh, Talant Sooronbaev, Craig D. Steinback, Mike Stembridge, Glenn Stewart, Tsering Stobdan, Giacomo Strapazzon, Andrew W. Subudhi, Erik Swenson, Thompson AA Roger, Patot MT van, Rosie Twomey, Silvia Ulrich, Nicolas Voituron, Dale R. Wagner, Shih Hao Wang, John B. West, Matt Wilkes, and Gabriel Willmann
Epigenomic Modifications Mediating Antibody Maturation, Emily C. Sheppard, Rikke Brandstrup Morrish, Michael J. Dillon, Rebecca Leyland, and Richard Chahwan
Atezolizumab versus chemotherapy in patients with platinum-treated locally advanced or metastatic urothelial carcinoma (IMvigor211): a multicentre, open-label, phase 3 randomised controlled trial, T Powles, I Duran, MS van der Heijden, and et al
Development and validation of Spasticity Index-Amyotrophic Lateral Sclerosis., K. Milinis, A. Tennant, R. J. Mills, A. Al-Chalabi, G. Burke, D. J. Dick, J. Ealing, C. O. Hanemann, T. Harrower, C. J. McDermott, T. Majeed, A. Pinto, K. Talbot, T. Williams, C. A. Young, and TONiC study group
An evaluation of medical student-led podcasts: what are the lessons learnt?, S Kapoor, R Catton, and H Khalil
Evaluation of a complex intervention (Engager) for prisoners with common mental health problems, near to and after release: study protocol for a randomised controlled trial., Tim Kirkpatrick, Charlotte Lennox, Rod Taylor, Rob Anderson, Michael Maguire, Mark Haddad, Susan Michie, Christabel Owens, Graham Durcan, Alex Stirzaker, William Henley, Caroline Stevenson, Lauren Carroll, Cath Quinn, Sarah Louise Brand, Tirril Harris, Amy Stewart, Roxanne Todd, Sarah Rybczynska-Bunt, Rebecca Greer, Mark Pearson, Jenny Shaw, and Richard Byng
Acalabrutinib in relapsed or refractory mantle cell lymphoma (ACE-LY-004): a single-arm, multicentre, phase 2 trial, M Wang, S Rule, and et al
Web-Based Intervention Using Behavioral Activation and Physical Activity for Adults With Depression (The eMotion Study): Pilot Randomized Controlled Trial (Preprint), JD Lambert, CJ Greaves, P Farrand, L Price, AM Haase, and AH Taylor
Rapid Review on Safeguarding to Update the Healthy Child Programme 5 to 19, N Axford, K Lowther, L Timmons, G Bjornstad, L Brook, L Webb, and S Sonthalia
NFAT-mediated defects in erythropoiesis cause anemia in Il2-/- mice., Sabrina Giampaolo, Gabriela Wójcik, Stefan Klein-Hessling, Edgar Serfling, and Amiya K. Patra
Evaluating a Dementia Learning Community: exploratory study and research implications, Rod Sheaff, Ian Sherriff, and Catherine Hagan Hennessy
General practitioner contributions to achieving sustained healthcare for offenders: a qualitative study, Cath Quinn, Katie Denman, Philippa Smithson, Christabel Owens, Rod Sheaff, John Campbell, Ian Porter, Jill Annison, and Richard Byng
Ibrutinib versus temsirolimus: 3-year follow-up of patients with previously treated mantle cell lymphoma from the phase 3, international, randomized, open-label RAY study., S Rule, W Jurczak, M Jerkeman, C Rusconi, and et al
Interventions to improve antimicrobial prescribing of doctors in training (IMPACT): a realist review, C Papoutsi, K Mattick, M Pearson, N Brennan, S Briscoe, and G Wong
Prospective, multicentre study of external ventricular drainage-related infections in the UK and Ireland, AAB Jamjoom and British Neurosurgical Trainee Research Collaborative
'Wrong' answers, right response: learning from randomised controlled trials when you don't get the results you were hoping for, N Axford, S Whelan, and T Hobbs
Global proteome and phosphoproteome analysis of meningiomas, Jemma Dunn, Sara Ferluga, Edwin Lasonder, and Oliver Hanemann
Cluster randomised controlled trial and economic and process evaluation to determine the effectiveness and cost-effectiveness of a novel intervention [Healthy Lifestyles Programme (HeLP)] to prevent obesity in school children., K Wyatt, J LLoyd, ES Creanor, C Green, SG Dean, M Hillsdon, C Abraham, R Tomlinson, V Pearson, RS Taylor, E Ryan, A Streeter, C McHugh, A Hurst, L Price, L Crathorne, C Krageloh, R Siegert, and S Logan
Consensus Clustering of temporal profiles for the identification of metabolic markers of pre-diabetes in childhood (EarlyBird 73), Mario Lauria, Maria Persico, Nikola Dordevic, Ornella Cominetti, Alice Matone, Joanne Hosking, Alison Jeffery, Jonathan Pinkney, Silva L Da, Corrado Priami, Ivan Montoliu, and François Pierre Martin
Physical activity and the prevention, reduction, and treatment of alcohol and/or substance use across the lifespan (The PHASE review): protocol for a systematic review, Tom P. Thompson, Adrian H. Taylor, Amanda Wanner, Kerryn Husk, Yinghui Wei, Siobhan Creanor, Rebecca Kandiyali, Jo Neale, Julia Sinclair, Mona Nasser, and Gary Wallace
Codesigning a Measure of Person-Centred Coordinated Care to Capture the Experience of the Patient: The Development of the P3CEQ, T Sugavanam, B Fosh, J Close, R Byng, J Horrell, and H Lloyd
Effectiveness of home-based exercise in older patients with advanced chronic obstructive pulmonary disease: A 3-year cohort study, Ritsuko Wakabayashi, Yuji Kusunoki, Kumiko Hattori, Takashi Motegi, Ryuko Furutate, Aki Itoh, Rupert C.M. Jones, Michael E. Hyland, and Kozui Kida
Improvement of fatigue, physical functioning, and well-being among patients with severe impairment at baseline receiving ibrutinib in combination with bendamustine and rituximab for relapsed chronic lymphocytic leukemia/small lymphocytic lymphoma in the HELIOS study., P Cramer, G Fraser, R Santucci-Silva, S Grosicki, and et al
Circulating miR-9 levels as a novel prognostic biomarker for highergrade meningioma, D Baiz, C Negroni, S Ferluga, E Ercolano, C Adams, and CO Hanemann
Decreasing the risk of sudden unexpected death in epilepsy: structured communication of risk factors for premature mortality in people with epilepsy, R. Shankar, W. Henley, C. Boland, R. Laugharne, B. N. McLean, C. Newman, J. Hanna, S. Ashby, M. C. Walker, and J. W. Sander
Diagnosis of lethal or prenatal‐onset autosomal recessive disorders by parental exome sequencing, Karen L. Stals, M Wakeling, Júlia Baptista, Richard Caswell, Andrew Parrish, Julia Rankin, Carolyn Tysoe, Garan Jones, Adam C. Gunning, Allen H Lango, Lisa Bradley, Angela F. Brady, Helena Carley, Jenny Carmichael, Bruce Castle, Deirdre Cilliers, Helen Cox, Charu Deshpande, Abhijit Dixit, Jacqueline Eason, Frances Elmslie, Andrew E. Fry, Alan Fryer, Muriel Holder, Tessa Homfray, Emma Kivuva, Victoria McKay, R Newbury‐Ecob, Michael Parker, Ravi Savarirayan, Claire Searle, Nora Shannon, Deborah Shears, Sarah Smithson, Ellen Thomas, Peter D. Turnpenny, Vinod Varghese, Pradeep Vasudevan, E Wakeling, Emma L. Baple, and Sian Ellard
Engaging Multiple Stakeholder Groups in the Development of Standards for Multiple Sclerosis Care: A Modified Delphi Process, J Hobart, A Bowen, L Eberhard, G Pepper, and G Giovannoni
Eslicarbazepine acetate as a replacement for levetiracetam in people with epilepsy developing behavioral adverse events, Rohit Shankar, Virupakshi Jalihal, William Henley, Mary Parrett, Phil Tittensor, Brendan N. McLean, Ammad Ahmed, and Josemir W. Sander
Etiology and treatment of neurodegenerative diseases, E Kramer
Evidence from a quasi-experimental study for the effectiveness of the influenza vaccination against myocardial infarction in UK adults aged at least 65 y, AJ Streeter and WE Henley
Gender-questioning children deserve better science, Richard Byng, Susan Bewley, Damian Clifford, and Margaret McCartney
High miR-9 levels represent a novel prognostic biomarker to predict development of malignant meningioma, D Baiz, C Negroni, S Ferluga, E Ercolano, C Adams, and CO Hanemann
Humanized mice to investigate neurodegenerative diseases, E Kramer
Improving the quality of cognitive screening assessments: ACEmobile, an iPad‐based version of the Addenbrooke's Cognitive Examination‐III, CGJ Newman, AD Bevins, JP Zajicek, JR Hodges, and et al
Increasing motivation and engagement in neurosurgery for medical students through practical simulation-based learning, John Hanrahan, Michail Sideris, Parmenion P. Tsitsopoulos, Alexios Bimpis, Terouz Pasha, Peter C. Whitfield, and Apostolos E. Papalois
Inequity of care provision and outcome disparity in autoimmune hepatitis in the United Kingdom, JK Dyson, Lin Lee Wong, Theophile Bigirumurame, Gideon M. Hirschfield, Stuart Kendrick, Ye H. Oo, Ansgar W. Lohse, MA Heneghan, David E.J. Jones, and Matthew Cramp
Interventions to improve antimicrobial prescribing of doctors in training (IMPACT): a realist review, N Brennan, C Papoutsi, K Mattick, M Pearson, S Briscoe, and G Wong
Longitudinal analyses of serum metabolite phenotypes in the EarlyBird cohort identify metabolic readouts associated with childhood insulin resistance, J Hosking, M Lauria, O Cominetti, A Jeffery, J Hager, J Pinkney, and F-P Martin
Low back pain, Tim Germon, Damian Clifford, William Lee, and Jeremy Hobart
Planning future CPD. What comes next?, J Winter, R Turner, L Spowart, and P Kneale
Prospective subgroup analyses of the randomized MCL‐002 (SPRINT) study: lenalidomide versus investigator's choice in relapsed or refractory mantle cell lymphoma, L Arcaini, T Lamy, J Walewski, D Belada, and et al
Real-world effectiveness of influenza vaccination in older adults in the UK from 1997-2012: A quasi-experimental cohort study, WE Henley and AJ Streeter
The British Neurosurgical Trainee Research Collaborative: Five years on, Aswin Chari, Aimun A. Jamjoom, Ellie Edlmann, Aminul I. Ahmed, Ian C. Coulter, Ruichong Ma, Paul May, Paul M. Brennan, Peter J.A. Hutchinson, and Angelos G. Kolias
The diagnostic test accuracy of rectal examination for prostate cancer diagnosis in symptomatic patients: a systematic review, Daniel Jones, Charlotte Friend, Andreas Dreher, Victoria Allgar, and Una Macleod
The Hyperhidrosis Disease Severity Measure-Axillary: Conceptualization and Development of Item Content, BM Kirsch, L Burke, J Hobart, D Angulo, and PS Walker
Transection and Crush Models of Nerve Injury to Measure Repair and Remyelination in Peripheral Nerve, Xin Peng Dun and David B. Parkinson
Trends of testing for and diagnosis of α 1 -antitrypsin deficiency in the UK: more testing is needed, JB Soriano, SJ Lucas, R Jones, M Miravitlles, V Carter, I Small, D Price, and R Mahadeva
Whole Mount Immunostaining on Mouse Sciatic Nerves to Visualize Events of Peripheral Nerve Regeneration, Xin Peng Dun and David B. Parkinson
Submissions from 2017
Epistaxis 2016: national audit of management, INTEGRATE, J Chynoweth, BG Jones, and K Stevens
Factors associated with junior doctors' decisions to apply for general practice training programmes in the UK: Secondary analysis of data from the UKMED project, Thomas C.E. Gale, Paul J. Lambe, and Martin J. Roberts
Making progression and award decisions, SA Burr, VM Salih, T Gale, D Moles, T Vallance, and D Bristow
A pre–post intervention study of pulmonary rehabilitation for adults with post-tuberculosis lung disease in Uganda, R Jones, BJ Kirenga, W Katagira, SJ Singh, J Pooler, A Okwera, R Kasiita, DG Enki, S Creanor, and A Barton
Adapting QOF to focus on wellbeing and health, James Close, Jose M. Valderas, Richard Byng, Nicky Britten, and Helen Lloyd
A comparison of inferential analysis methods for multilevel studies: Implications for drawing conclusions in animal welfare science, KN Stevens, L Asher, K Griffin, M Friel, and N O'Connell
An experimental model to measure the ability of headphones with active noise control to reduce patient’s exposure to noise in an intensive care unit, S Gallacher, D Enki, S Stevens, and MJ Bennett
Comparative costs and activity from a sample of UK clinical trials units, D Hind, BC Reeves, S Bathers, C Bray, and et al
Effectiveness of the Healthy Lifestyles Programme (HeLP) to prevent obesity in UK primary-school children: a cluster randomised controlled trial, J Lloyd, E Creanor, S Logan, C Green, SG Dean, M Hillsdon, C Abrahan, R Tomlinson, V Pearson, RS Taylor, E Ryan, L Price, A Streeter, and K Wyatt
How do healthcare professionals interview patients to assess suicide risk?, Rose McCabe, Imren Sterno, Stefan Priebe, Rebecca Barnes, and Richard Byng
Intervention fidelity in the definitive cluster randomised controlled trial of the Healthy Lifestyles Programme (HeLP) trial: findings from the process evaluation, J Lloyd, S Dean, S Creanor, C Abraham, and et al
Is Good Clinical Practice Becoming Poor Clinical Care?, S Le Gouill, M Dreyling, MD Caballero, M Andre, and et al
Lessons learned from the London Exercise and Pregnant (LEAP) Smokers randomised controlled trial process evaluation: implications for the design of physical activity for smoking cessation interventions during pregnancy, Nikoletta Giatras, Elisabeth Wanninkhof, Miranda Leontowitsch, Beth Lewis, Adrian Taylor, Sue Cooper, and Michael Ussher
NFATc1 controls the cytotoxicity of CD8+ T cells, Stefan Klein-Hessling, Khalid Muhammad, Matthias Klein, Tobias Pusch, Ronald Rudolf, Jessica Flöter, Musga Qureischi, Andreas Beilhack, Martin Vaeth, Carsten Kummerow, Christian Backes, Rouven Schoppmeyer, Ulrike Hahn, Markus Hoth, Tobias Bopp, Friederike Berberich-Siebelt, Amiya Patra, Andris Avots, Nora Müller, Almut Schulze, and Edgar Serfling
