Submissions from 2018
Noninvasive options for ‘wearing-off’ in Parkinson's disease: a clinical consensus from a panel of UK Parkinson's disease specialists, CB Carroll, R Fackrell, D Grosset, B Mohamed, P Reddy, M Parry, K Chaudhuri, and T Foltynie
Regulation of Aspergillus nidulans CreA-Mediated Catabolite Repression by the F-Box Proteins Fbx23 and Fbx47, Ozgur Bayram, Leandro Jose De Assis, Mevlut Ulas, Laure Nicolas Annick Ries, Ramli NAM El, Ozlem Sarikaya-Bayram, Gerhard H. Braus, and Gustavo Henrique Goldman
A British Society for Haematology Good Practice Paper on the Diagnosis and Investigation of Patients with Mantle Cell Lymphoma, P McKay, M Leach, B Jackson, S Robinson, and SAJ Rule
Guideline for the Management of Mantle Cell Lymphoma, SAJ Rule, P McKay, M Leach, R Jackson, and S Robinson
Postoperative Remote Automated Monitoring: Need for and State of the Science, MH McGillion and PROTECT Network Investigators
Trends of testing for and diagnosis of α 1 -antitrypsin deficiency in the UK: more testing is needed, JB Soriano, SJ Lucas, R Jones, M Miravitlles, and et al
Under representation of people with epilepsy and intellectual disability in research, Rohit Shankar, Charles Rowe, Alje Van Hoorn, William Henley, Richard Laugharne, David Cox, Raj Pande, Ashok Roy, and Josemir W. Sander
B cell development is critically dependent on NFATc1 activity, Amiya K. Patra, Sabrina Giampaolo, Gabriela Wójcik, Stefan Klein-Hessling, and Edgar Serfling
Supplementary search methods were more effective and offered better value than bibliographic database searching: a case study from public health and environmental enhancement., Chris Cooper, Rebecca Lovell, Kerryn Husk, Andrew Booth, and Ruth Garside
Orbital infections: a complete cycle 7-year audit and a management guideline, M Atfeh, K Singh, and HS Khalil
Confidentiality, anonymity and amnesty for midwives in distress seeking online support – Ethical?, S Pezaro, W Clyne, and C Gerada
Targeting Gpr52 lowers mutant HTT levels and rescues Huntington's disease-associated phenotypes., Boxun Lu, Haikun Song, H Li, Shimeng Guo, Yuyin Pan, Yuhua Fu, Zijian Zhou, Z Li, Xue Wen, Xiaoli Sun, Bingqing He, Haifeng Gu, Quan Zhao, Cen Wang, Ping An, Shouqing Luo, Youhong Hu, and Xin Xie
A pilot randomised controlled trial investigating a mindfulness-based stress reduction (MBSR) intervention in individuals with pulmonary arterial hypertension (PAH): the PATHWAYS study, RMR Tulloh, V Garratt, J Tagney, J Turner-Cobb, and et al
Etiology and treatment of Parkinson Disease, E Kramer
Physical activity for antenatal and postnatal depression in women attempting to quit smoking: randomised controlled trial, Amanda Daley, Muhammad Riaz, S Lewis, Paul Aveyard, Tim Coleman, Isaac Manyonda, Robert West, B Lewis, Bess Marcus, Adrian Taylor, Judith Ibison, Andrew Kent, and Michael Ussher
Ultramicroscopy/lightsheet-microscopy in dementia, E Kramer
A systematic review and consensus definitions for standardised end-points in perioperative medicine: pulmonary complications, RM Pearse and StEP-COMPAC Group
Children’s Compliance With Wrist-Worn Accelerometry Within a Cluster-Randomized Controlled Trial: Findings From the Healthy Lifestyles Programme, L Price, K Wyatt, J Lloyd, C Abraham, and et al
Desperately seeking outcomes: quantifying the effectiveness of community mental healthcare using Health of the Nation Outcome Scales, R Laugharne, S Eaves, A Mascas, K Psatha, and et al
Desperately seeking outcomes: Quantifying the effectiveness of community mental healthcare using Health of the Nation Outcome Scales, Richard Laugharne, Scott Eaves, Alin Mascas, Kiki Psatha, Gill Dinnis, Jonathan Trower, and Rohit Shankar
Evaluating the development of medical revalidation in England and its impact on organisational performance and medical practice: overview report, J Archer, K Bloor, C Bojke, A Boyd, M Bryce, J Ferguson, N Gutacker, C Hillier, K Luscombe, T Price, de Bere S Regan, A Tazzyman, J Tredinnick-Rowe, and K Walshe
‘It's a silver lining’: A template analysis of satisfaction and quality of life following post‐mastectomy breast reconstruction, H Matthews, A Turner, I Williamson, and W Clyne
Mental Health in UK Biobank - development, implementation and results from an online questionnaire completed by 157,366 participants, WE Lee, K Davis, J Coleman, M Adams, and et al
UMbRELLA: Evaluating the regulatory impacts of medical revalidation – final report., J Archer, N Cameron, M Lewis, M Marshall, J O'Hanlon, de Bere S Regan, K Walshe, R Baines, A Boyd, M Bryce, J Ferguson, E Gabe-Thomas, S Holmes, M Lalani, T Price, P Rae, M Roberts, S Stevens, A Tazzyman, J Tredinnick-Rowe, J Wakeling, and D Zahra
The International Landscape of Medical Licensing Examinations: A Typology Derived From a Systematic Review, Julian Archer, Tristan Price, Nick Lynn, Lee Coombes, Martin Roberts, Tom Gale, and de Bere S Regan
Has the time come to stratify and score SUDEP risk to inform people with epilepsy of their changes in safety?, Rohit Shankar, Craig Newman, Alistair Gales, Brendan N. McLean, Jane Hanna, Samantha Ashby, Matthew C. Walker, and Josemir W. Sander
IMPACT OF DEMENTIA CARE HOME LEARNING COMMUNITY IN DEMENTIA CARE HOMES IN TORBAY, DEVON, UK, A Rana, D Somerfield, and R Sheaff
Ret protects the midbrain dopaminergic system against α- synuclein toxicity., E Kramer
Using Social Media to Generate and Collect Primary Data: The #ShowsWorkplaceCompassion Twitter Research Campaign, W Clyne, S Pezaro, K Deeny, and R Kneafsey
A Case of Invasive Sinonasal Carcinosarcoma: The Importance of Early Detection, J Yuen, V Varadarajan, M Stavrakas, S Muquit, and H Khalil
Moral narratives and mental health: rethinking understandings of distress and healthcare support in contexts of austerity and welfare reform, Felicity Thomas, Lorraine Hansford, Joseph Ford, Katrina Wyatt, Rosemarie McCabe, and Richard Byng
Interventions for reducing unplanned paediatric admissions: an observational study in one hospital, Kerryn Husk, Vashti Berry, Richard Tozer, Gina Skipwith, Robert Radmore, Susan Ball, Obioha C. Ukoumunne, and Stuart Logan
Prescribing gardening and conservation activities for health and wellbeing in older people, Kerryn Husk, Rebecca Lovell, and Ruth Garside
Implication of Major Adverse Postoperative Events and Myocardial Injury on Disability and Survival: A Planned Subanalysis of the ENIGMA-II Trial., WS Beattie and et al
The Role of Pedagogy in Clinical Education, J Tredinnick-Rowe
Digital care in epilepsy: A conceptual framework for technological therapies, Rohit Shankar, Rupert Page, Brendan N. McLean, Jane Hanna, and Craig Newman
Video-calls to reduce loneliness and social isolation within care environments for older people: an implementation study using collaborative action research, Sonam Zamir, Catherine Hagan Hennessy, Adrian H. Taylor, and Ray B. Jones
Association between Household Air Pollution Exposure and Chronic Obstructive Pulmonary Disease Outcomes in 13 Low- and Middle-Income Country Settings., T Siddharthan, MR Grigsby, D Goodman, M Chowdhury, A Rubinstein, V Irazola, L Gutierrez, JJ Miranda, A Bernabe-Ortiz, D Alam, B Kirenga, R Jones, Gemert F van, RA Wise, and W Checkley
Atezolizumab in Platinum-treated Locally Advanced or Metastatic Urothelial Carcinoma: Outcomes by Prior Number of Regimens., JL Perez-Gracia, Y Loriot, JE Rosenberg, T Powles, and et al
From Programme Theory to Logic Models for Multispecialty Community Providers: A Realist Evidence Synthesis, WR Sheaff, S Brand, H LLoyd, A Wanner, M Fornasiero, S Briscoe, J Valderas, R Byng, and M Pearson
Epigenomic Modifications Mediating Antibody Maturation, Richard Chahwan, Emily C. Sheppard, Rikke Brandstrup Morrish, Michael J. Dillon, and Rebecca Leyland
Atezolizumab versus chemotherapy in patients with platinum-treated locally advanced or metastatic urothelial carcinoma (IMvigor211): a multicentre, open-label, phase 3 randomised controlled trial, T Powles, I Duran, MS van der Heijden, and et al
Development and validation of Spasticity Index-Amyotrophic Lateral Sclerosis., C. A. Young, K. Milinis, A. Tennant, R. J. Mills, A. Al-Chalabi, G. Burke, D. J. Dick, J. Ealing, C. O. Hanemann, T. Harrower, C. J. McDermott, T. Majeed, A. Pinto, K. Talbot, T. Williams, and TONiC study group
An evaluation of medical student-led podcasts: what are the lessons learnt?, S Kapoor, R Catton, and H Khalil
Evaluation of a complex intervention (Engager) for prisoners with common mental health problems, near to and after release: study protocol for a randomised controlled trial., Tim Kirkpatrick, Charlotte Lennox, Rod Taylor, Rob Anderson, Michael Maguire, Mark Haddad, Susan Michie, Christabel Owens, Graham Durcan, Alex Stirzaker, William Henley, Caroline Stevenson, Lauren Carroll, Cath Quinn, Sarah Louise Brand, Tirril Harris, Amy Stewart, Roxanne Todd, Sarah Rybczynska-Bunt, Rebecca Greer, Mark Pearson, Jenny Shaw, and Richard Byng
Acalabrutinib in relapsed or refractory mantle cell lymphoma (ACE-LY-004): a single-arm, multicentre, phase 2 trial, M Wang, S Rule, and et al
Web-Based Intervention Using Behavioral Activation and Physical Activity for Adults With Depression (The eMotion Study): Pilot Randomized Controlled Trial (Preprint), JD Lambert, CJ Greaves, P Farrand, L Price, AM Haase, and AH Taylor
Rapid Review on Safeguarding to Update the Healthy Child Programme 5 to 19, N Axford, K Lowther, L Timmons, G Bjornstad, L Brook, L Webb, and S Sonthalia
NFAT-mediated defects in erythropoiesis cause anemia in Il2-/- mice., Amiya K. Patra, Sabrina Giampaolo, Gabriela Wójcik, Stefan Klein-Hessling, and Edgar Serfling
Evaluating a Dementia Learning Community: exploratory study and research implications, Rod Sheaff, Ian Sherriff, and Catherine Hagan Hennessy
General practitioner contributions to achieving sustained healthcare for offenders: a qualitative study, Cath Quinn, Katie Denman, Philippa Smithson, Christabel Owens, Rod Sheaff, John Campbell, Ian Porter, Jill Annison, and Richard Byng
Ibrutinib versus temsirolimus: 3-year follow-up of patients with previously treated mantle cell lymphoma from the phase 3, international, randomized, open-label RAY study., S Rule, W Jurczak, M Jerkeman, C Rusconi, and et al
Interventions to improve antimicrobial prescribing of doctors in training (IMPACT): a realist review, C Papoutsi, K Mattick, M Pearson, N Brennan, S Briscoe, and G Wong
Prospective, multicentre study of external ventricular drainage-related infections in the UK and Ireland, AAB Jamjoom and British Neurosurgical Trainee Research Collaborative
'Wrong' answers, right response: learning from randomised controlled trials when you don't get the results you were hoping for, N Axford, S Whelan, and T Hobbs
Global proteome and phosphoproteome analysis of meningiomas, Jemma Dunn, Sara Ferluga, Edwin Lasonder, and Oliver Hanemann
Cluster randomised controlled trial and economic and process evaluation to determine the effectiveness and cost-effectiveness of a novel intervention [Healthy Lifestyles Programme (HeLP)] to prevent obesity in school children., K Wyatt, J LLoyd, ES Creanor, C Green, SG Dean, M Hillsdon, C Abraham, R Tomlinson, V Pearson, RS Taylor, E Ryan, A Streeter, C McHugh, A Hurst, L Price, L Crathorne, C Krageloh, R Siegert, and S Logan
Consensus Clustering of temporal profiles for the identification of metabolic markers of pre-diabetes in childhood (EarlyBird 73), Mario Lauria, Maria Persico, Nikola Dordevic, Ornella Cominetti, Alice Matone, Joanne Hosking, Alison Jeffery, Jonathan Pinkney, Silva L Da, Corrado Priami, Ivan Montoliu, and François Pierre Martin
Physical activity and the prevention, reduction, and treatment of alcohol and/or substance use across the lifespan (The PHASE review): protocol for a systematic review, Tom P. Thompson, Adrian H. Taylor, Amanda Wanner, Kerryn Husk, Yinghui Wei, Siobhan Creanor, Rebecca Kandiyali, Jo Neale, Julia Sinclair, Mona Nasser, and Gary Wallace
Codesigning a Measure of Person-Centred Coordinated Care to Capture the Experience of the Patient: The Development of the P3CEQ, T Sugavanam, B Fosh, J Close, R Byng, J Horrell, and H Lloyd
Effectiveness of home-based exercise in older patients with advanced chronic obstructive pulmonary disease: A 3-year cohort study, Kozui Kida, Ritsuko Wakabayashi, Yuji Kusunoki, Kumiko Hattori, Takashi Motegi, Ryuko Furutate, Aki Itoh, Rupert C.M. Jones, and Michael E. Hyland
Improvement of fatigue, physical functioning, and well-being among patients with severe impairment at baseline receiving ibrutinib in combination with bendamustine and rituximab for relapsed chronic lymphocytic leukemia/small lymphocytic lymphoma in the HELIOS study., P Cramer, G Fraser, R Santucci-Silva, S Grosicki, and et al
Application of prognostic scores in the STOPAH trial: Discriminant function is no longer the optimal scoring system in alcoholic hepatitis, Ewan H. Forrest, Stephen R. Atkinson, Paul Richardson, Steven Masson, Stephen Ryder, Mark R. Thursz, Michael Allison, Anne McCune, Dermot Gleeson, Andrew Austin, David Patch, Ashwin Dhanda, Debbie Shawcross, and Mark Wright
Can practitioners use patient reported measures to enhance person centred coordinated care in practice? A qualitative study, Hannah Wheat, Jane Horrell, Jose M. Valderas, James Close, Ben Fosh, and Helen Lloyd
Circulating miR-9 levels as a novel prognostic biomarker for highergrade meningioma, D Baiz, C Negroni, S Ferluga, E Ercolano, C Adams, and CO Hanemann
Clinical chronobiology: a timely consideration in critical care medicine, Daniel Martin, Helen McKenna, der Horst GTJ van, and Irwin Reiss
Correction to: Ret is essential to mediate GDNF’s neuroprotective and neuroregenerative effect in a Parkinson disease mouse model, Jorg B. Schulz, Anja Drinkut, Karsten Tillack, Durga P. Meka, Sebastian Kügler, and Edgar R. Kramer
Decreasing the risk of sudden unexpected death in epilepsy: structured communication of risk factors for premature mortality in people with epilepsy, R. Shankar, W. Henley, C. Boland, R. Laugharne, B. N. McLean, C. Newman, J. Hanna, S. Ashby, M. C. Walker, and J. W. Sander
Designing a care pathway for high risk parkinson’s patients, TLY Chloe, T Dominey, E Pearson, F Murphy, and C Carroll
Diagnosis of lethal or prenatal‐onset autosomal recessive disorders by parental exome sequencing, Sian Ellard, Karen L. Stals, M Wakeling, Júlia Baptista, Richard Caswell, Andrew Parrish, Julia Rankin, Carolyn Tysoe, Garan Jones, Adam C. Gunning, Allen H Lango, Lisa Bradley, Angela F. Brady, Helena Carley, Jenny Carmichael, Bruce Castle, Deirdre Cilliers, Helen Cox, Charu Deshpande, Abhijit Dixit, Jacqueline Eason, Frances Elmslie, Andrew E. Fry, Alan Fryer, Muriel Holder, Tessa Homfray, Emma Kivuva, Victoria McKay, R Newbury‐Ecob, Michael Parker, Claire Searle, Nora Shannon, Deborah Shears, Sarah Smithson, Ellen Thomas, Peter D. Turnpenny, Vinod Varghese, Pradeep Vasudevan, E Wakeling, Emma L. Baple, and Sian Ellard
Differential phosphorylation and n-terminal configuration of capsid subunits in parvovirus assembly and viral trafficking, J Gil-Ranedo, E Hernando, N Valle, L Riolobos, B Maroto, and JM Almendral
Discrimination, harassment and non-reporting in UK medical education, Jonathan Broad, Marion Matheson, Fabienne Verrall, Anna K. Taylor, Daniel Zahra, Louise Alldridge, and Gene Feder
Empowering students with the hidden curriculum, Hilary Neve and Tracey Collett
Engaging Multiple Stakeholder Groups in the Development of Standards for Multiple Sclerosis Care: A Modified Delphi Process, J Hobart, A Bowen, L Eberhard, G Pepper, and G Giovannoni
Engaging Without Exposing: Use of a Fictional Character to Facilitate Mental Health Talk in Focus Groups With Men Who Have Been Subject to the Criminal Justice System, Christabel Owens, Mary Carter, Deborah Shenton, Richard Byng, and Cath Quinn
Enhanced natural killer cell activity is found in exposed uninfected recipients of hepatitis C-contaminated blood, M. M. Ow, D. Hegazy, U. M. Warshow, and M. E. Cramp
Eslicarbazepine acetate as a replacement for levetiracetam in people with epilepsy developing behavioral adverse events, Rohit Shankar, Virupakshi Jalihal, William Henley, Mary Parrett, Phil Tittensor, Brendan N. McLean, Ammad Ahmed, and Josemir W. Sander
Etiology and treatment of neurodegenerative diseases, E Kramer
Evaluating the clinical utility of the parkinson’s kinetigraph (PKG), L Hutchinson, T Dominey, E Pearson, F Murphy, L Bell, and C Carroll
Evidence from a quasi-experimental study for the effectiveness of the influenza vaccination against myocardial infarction in UK adults aged at least 65 y, AJ Streeter and WE Henley
Exercise for people with Parkinson’s: a practical approach, Bhanu Ramaswamy, Julie Jones, and Camille Carroll
Factors influencing treatment escalation from long-acting muscarinic antagonist monotherapy to triple therapy in patients with COPD: a retrospective THIN-database analysis, JR Hurst, M Dilleen, K Morris, S Hills, B Emir, and R Jones
First comprehensive tool for screening pain in Parkinson's disease: The King's Parkinson's Disease Pain Questionnaire (KPPQ)., P. Martinez-Martin, A. M. Rizos, J. Wetmore, A. Antonini, P. Odin, S. Pal, R. Sophia, C. Carroll, D. Martino, C. Falup-Pecurariu, B. Kessel, T. Andrews, D. Paviour, C. Trenkwalder, K. R. Chaudhuri, and EUROPAR & MDS Non-Motor PD Study Group
Gender-questioning children deserve better science, Richard Byng, Susan Bewley, Damian Clifford, and Margaret McCartney
Health trainer-led motivational intervention plus usual care for people under community supervision compared with usual care alone: a study protocol for a parallel-group pilot randomised controlled trial (STRENGTHEN), Tom P. Thompson, Lynne Callaghan, Emma Hazeldine, Cath Quinn, Samantha Walker, Richard Byng, Gary Wallace, Siobhan Creanor, Colin Green, Annie Hawton, Jill Annison, Julia Sinclair, Jane Senior, and Adrian H. Taylor
High miR-9 levels represent a novel prognostic biomarker to predict development of malignant meningioma, D Baiz, C Negroni, S Ferluga, E Ercolano, C Adams, and CO Hanemann
Humanized mice to investigate neurodegenerative diseases, E Kramer
Identifying enablers and barriers to individually tailored prescribing: a survey of healthcare professionals in the UK, Joanne Reeve, Nicky Britten, Richard Byng, Jo Fleming, Janet Heaton, and Janet Krska
Impact of the SIGN head injury guidelines and NHS 4-hour emergency target on hospital admissions for head injury in Scotland: an interrupted times series, Carl Marincowitz, Fiona E. Lecky, Eleanor Morris, Victoria Allgar, and Trevor A. Sheldon
Improving community exercise provision in Parkinson’s, M Palin, J Rideout, C Carroll, and V Evans
Improving the quality of cognitive screening assessments: ACEmobile, an iPad‐based version of the Addenbrooke's Cognitive Examination‐III, CGJ Newman, AD Bevins, JP Zajicek, JR Hodges, and et al
Increasing motivation and engagement in neurosurgery for medical students through practical simulation-based learning, John Hanrahan, Michail Sideris, Parmenion P. Tsitsopoulos, Alexios Bimpis, Terouz Pasha, Peter C. Whitfield, and Apostolos E. Papalois
Inequity of care provision and outcome disparity in autoimmune hepatitis in the United Kingdom, JK Dyson, Lin Lee Wong, Theophile Bigirumurame, Gideon M. Hirschfield, Stuart Kendrick, Ye H. Oo, Ansgar W. Lohse, MA Heneghan, David E.J. Jones, and Matthew Cramp
Insulin resistance is higher in prepubertal girls but switches to become higher in boys at age 16: A Cohort Study (EarlyBird 57), Jonathan Pinkney, SC Jeffery, Joanne Hosking, AN Jeffery, Michael J. Murphy, Linda D. Voss, and Terence J. Wilkin
International consensus on quality standards for multiple sclerosis care: results from a modified Delphi process, J Hobart, A Bowen, L Eberhard, G Pepper, and G Giovannoni
Intervention Delivery Fidelity Assessment of a Counseling-Based Intervention for Promoting Smoking Reduction and Increasing Physical Activity, Tom P. Thompson, Jeffrey D. Lambert, Colin J. Greaves, and Adrian H. Taylor
Interventions to improve antimicrobial prescribing of doctors in training (IMPACT): a realist review, N Brennan, C Papoutsi, K Mattick, M Pearson, S Briscoe, and G Wong
Longitudinal analyses of serum metabolite phenotypes in the EarlyBird cohort identify metabolic readouts associated with childhood insulin resistance, J Hosking, M Lauria, O Cominetti, A Jeffery, J Hager, J Pinkney, and F-P Martin
