ORCID
- Hobart, Jeremy: 0000-0002-2114-7920
Abstract
BACKGROUND: The United States Food and Drug Administration (FDA) are currently producing guidelines for the scientific adequacy of patient reported outcome measures (PROMs) in clinical trials, which will have implications for the selection of scales used in future clinical trials. In this study, we examine how the Cervical Dystonia Impact Profile (CDIP-58), a rigorous Rasch measurement developed neurologic PROM, stands up to traditional psychometric criteria for three reasons: 1) provide traditional psychometric evidence for the CDIP-58 in line with proposed FDA guidelines; 2) enable researchers and clinicians to compare it with existing dystonia PROMs; and 3) help researchers and clinicians bridge the knowledge gap between old and new methods of reliability and validity testing. METHODS: We evaluated traditional psychometric properties of data quality, scaling assumptions, targeting, reliability and validity in a group of 391 people with CD. The main outcome measures used were the CDIP-58, Medical Outcome Study Short Form-36, the 28-item General Health Questionnaire, and Hospital and Anxiety and Depression Scale. RESULTS: A total of 391 people returned completed questionnaires (corrected response rate 87%). Analyses showed: 1) data quality was high (low missing data < or = 4%, subscale scores could be computed for > 96% of the sample); 2) item groupings passed tests for scaling assumptions; 3) good targeting (except for the Sleep subscale, ceiling effect = 27%); 4) good reliability (Cronbach's alpha > or = 0.92, test-retest intraclass correlations > or = 0.83); and 5) validity was supported. CONCLUSION: This study has shown that new psychometric methods can produce a PROM that stands up to traditional criteria and supports the clinical advantages of Rasch analysis.
DOI
10.1186/1477-7525-6-58
Publication Date
2008-08-06
Publication Title
Health Qual Life Outcomes
Volume
6
Organisational Unit
Peninsula Medical School
Keywords
Humans, Outcome Assessment, Health Care, Psychometrics, Reproducibility of Results, Sickness Impact Profile, Surveys and Questionnaires, Torticollis
Recommended Citation
Cano, S. J., Warner, T., Thompson, A., Bhatia, K., Fitzpatrick, R., & Hobart, J. (2008) 'The cervical dystonia impact profile (CDIP-58): can a Rasch developed patient reported outcome measure satisfy traditional psychometric criteria?', Health Qual Life Outcomes, 6. Available at: https://doi.org/10.1186/1477-7525-6-58
