Browse research from the Peninsula Medical School.

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Submissions from 2015

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Identifying an important change estimate for the Multiple Sclerosis Walking Scale-12 (MSWS-12v1) for interpreting clinical trial results, Kathleen W. Wyrwich, Lahar Mehta, Manjit McNeill, Jeremy Hobart, Jiat Ling Poon, Priscilla Auguste, John Zhong, and Jacob Elkins

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Safety and efficacy of diaphragm pacing in patients with respiratory insufficiency due to amyotrophic lateral sclerosis (DiPALS): A multicentre, open-label, randomised controlled trial, Christopher J. McDermott, DiPALS Writing Committee, DiPALS Study Group Collaborators, Pamela J. Shaw, Cindy L. Cooper, Simon Dixon, Wendy O. Baird, Mike J. Bradburn, Patrick Fitzgerald, Chin Maguire, Susan K. Baxter, Tim Williams, Simon V. Baudouin, Dayalan Karat, Kevin Talbot, John Stradling, Nick Maynard, Martin Turner, Abeezar Sarela, Stephen Bianchi, Roger Ackroyd, Stephen C. Bourke, John Ealing, Hisham Hamdalla, Carolyn Young, Andrew Bentley, Simon Galloway, Richard W. Orrell, Wisia Wedzicha, Mark Elliot, C. Oliver Hanemann, Ibrahim Imam, Anita K. Simonds, Lyn Taylor, Roger Leek, Nigel Leigh, Michael Dewey, and Aleksandar Radunovic

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Integration and Continuity of Primary Care: Polyclinics and Alternatives, a Patient-Centred Analysis of How Organisation Constrains Care Coordination, WR Sheaff, J Halliday, J Øvretveit, R Byng, M Exworthy, S Peckham, and S Asthana

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An Efficient and Versatile System for Visualization and Genetic Modification of Dopaminergic Neurons in Transgenic Mice, Karsten Tillack, Helia Aboutalebi, and Edgar R. Kramer

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Rapid diagnostics for melioidosis: a comparative study of a novel lateral flow antigen detection assay, Robert Norton, Gemma Robertson, Alanna Sorenson, Brenda Govan, Natkunam Ketheesan, Raymond Houghton, Hongjing Chen, David Aucoin, and Michael Dillon

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Epstein–Barr virus-encoded microRNA BART1 induces tumour metastasis by regulating PTEN-dependent pathways in nasopharyngeal carcinoma, L Cai, Y Ye, Q Jiang, Y Chen, and et al

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Gastrostomy in patients with amyotrophic lateral sclerosis (ProGas): A prospective cohort study, Christopher J. McDermott, ProGas Study Group, and Oliver Hanemann

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PAin SoluTions In the Emergency Setting (PASTIES)--patient controlled analgesia versus routine care in emergency department patients with non-traumatic abdominal pain: randomised trial, JE Smith, M Rockett, S Creanor, R Squire, and et al

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PAin SoluTions In the Emergency Setting (PASTIES)--patient controlled analgesia versus routine care in emergency department patients with pain from traumatic injuries: randomised trial, JE Smith, M Rockett, E Creanor, R Squire, and et al

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The Mammalian Cell Cycle Regulates Parvovirus Nuclear Capsid Assembly, J Gil-Ranedo, E Hernando, L Riolobos, C Domínguez, M Kann, and JM Almendral

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Sympathetic autonomic dysfunction and impaired cardiovascular performance in higher risk surgical patients: implications for perioperative sympatholysis, J Whittle, N Alexander, RCM Stephens, JM Otto, DS Martin, JR Sneyd, Struthers, G Minto, and GL Ackland

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Assessing doctors’ competencies using multisource feedback: validating a Japanese version of the Sheffield Peer Review Assessment Tool (SPRAT), H Sasaki, J Archer, N Yonemoto, R Mori, and et al

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Between Arts and Biological Science. Green Technology and the Concept of Phytomining, M Gapševičius, Diaz J Pablo, L Rukevičiūtė, B Degger, and JF Tredinnick-Rowe

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XIAP and cIAP1 amplifications induce Beclin 1-dependent autophagy through NFκB activation., David C. Rubinsztein, Fang Lin, Ghita Ghislat, Shouqing Luo, Maurizio Renna, and Farah Siddiqi

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Physical activity for smoking cessation in pregnancy: randomised controlled trial, Michael Ussher, S Lewis, Paul Aveyard, Isaac Manyonda, Robert West, B Lewis, Bess Marcus, Muhammad Riaz, Adrian Taylor, Amanda Daley, and Tim Coleman

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Comparing the risk profiles of self-harming patients with those who leave paper suicide notes with those who leave messages via new media., JR Barrett, H Shetty, M Broadbent, S Cross, and et al

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Keeping patients with epilepsy safe: a surmountable challenge?, Rohit Shankar, Craig Newman, Jane Hanna, Juliet Ashton, Caryn Jory, Brendan Mclean, Tamsyn Anderson, Matthew Walker, David Cox, and Liz Ewins

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Adherence of patients to long-term medication: a cross-sectional study of antihypertensive regimens in Austria, F Lötsch, L Auer-Hackenberg, M Groger, K Rehman, and et al

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Coital incontinence: what can we learn from urodynamic assessment?, K Madhu, H Hashim, DG Enki, M Yaasin, and M Drake

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Meta-analysis of Androgen Insensitivity in Preoperative Hormone Therapy in Hypospadias, W Zhao, J Yin, Z Yang, J Xie, and et al

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Implementing a patient-initiated review system in rheumatoid arthritis: a qualitative evaluation., Victoria A. Goodwin, Sue Child, Mark G. Perry, Christian A. Gericke, and Richard Byng

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Core intended learning outcomes for tackling health inequalities in undergraduate medicine., AE Williamson, R Ayres, J Allen, and U Macleod

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Common patterns of morbidity and multi-morbidity and their impact on health-related quality of life: evidence from a national survey, RE Mujica-Mota, M Roberts, G Abel, M Elliott, and et al

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NHS commissioning practice and health system governance: a mixed-methods realistic evaluation, WR Sheaff, N Charles, A Mahon, N Chambers, V Morando, M Exworthy, R Byng, R Mannion, and S Llewellyn

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Acute Effects of Brisk Walking on Sugary Snack Cravings in Overweight People, Affect and Responses to a Manipulated Stress Situation and to a Sugary Snack Cue: A Crossover Study, Larissa Ledochowski, Gerhard Ruedl, Adrian H. Taylor, and Martin Kopp

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Improving community health networks for people with severe mental illness: a case study investigation, V Pinfold, D Sweet, I Porter, C Weyer-Brown, R Byng, and C Griffiths

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Medical student and junior doctors’ tolerance of ambiguity: development of a new scale, J Hancock, M Roberts, L Monrouxe, and K Mattick

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Predictors of Self-Reported Adherence to Antihypertensive Medicines: A Multinational, Cross-Sectional Survey, VL Morrison, EAF Holmes, S Parveen, CO Plumpton, and et al

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An investigation into the effects of different types of exercise on the maintenance of approach motivation levels, J. A.S. Lowenstein, K. Wright, A. Taylor, and N. J. Moberly

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Combining behavioural activation with physical activity promotion for adults with depression: findings of a parallel-group pilot randomised controlled trial (BAcPAc), Claire Pentecost, Paul Farrand, Colin J. Greaves, RS Taylor, Fiona C. Warren, Melvyn Hillsdon, Colin Green, Jo R. Welsman, Kat Rayson, Philip H. Evans, and AH Taylor

Core outcome sets for use in effectiveness trials involving people with bipolar and schizophrenia in a community-based setting (PARTNERS2): study protocol for the development of two core outcome sets, Thomas Keeley, Humera Khan, Vanessa Pinfold, Paula Williamson, Jonathan Mathers, Linda Davies, Ruth Sayers, Elizabeth England, Siobhan Reilly, Richard Byng, Linda Gask, Mike Clark, Peter Huxley, Peter Lewis, Maximillian Birchwood, and Melanie Calvert

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Defining competence in obstetric epidural anaesthesia for inexperienced trainees, E. J. Drake, J. Coghill, and J. R. Sneyd

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Effectiveness and micro-costing of the KiVa school-based bullying prevention programme in Wales: study protocol for a pragmatic definitive parallel group cluster randomised controlled trial, Suzy Clarkson, Nick Axford, Vashti Berry, Rhiannon Tudor Edwards, Gretchen Bjornstad, Zoe Wrigley, Joanna Charles, Zoe Hoare, Obioha C. Ukoumunne, Justin Matthews, and Judy Hutchings

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Energy expenditure on recreational visits to different natural environments, Lewis R. Elliott, Mathew P. White, Adrian H. Taylor, and Stephen Herbert

From Inpatient Notes to Outpatient Followup: Enhancing the Rhinology Service in a Tertiary Centre through Student Led Projects, M Sayma, R Hyne, M Sharma, L Kyle, Khatwa M Abo, I MacKay-Davies, A Poulios, and HS Khalil

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HCV treatment rates and sustained viral response among people who inject drugs in seven UK sites: real world results and modelling of treatment impact, Natasha K. Martin, G. R. Foster, J. Vilar, S. Ryder, M. E. Cramp, F. Gordon, J. F. Dillon, N. Craine, H. Busse, A. Clements, S. J. Hutchinson, A. Ustianowski, M. Ramsay, D. J. Goldberg, W. Irving, V. Hope, Angelis D De, M. Lyons, P. Vickerman, and M. Hickman

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Identifying a Minimally Important Change Threshold for The Multiple Sclerosis Walking Scale-12 (MSWS-12), L Mehta, M McNeill, J Hobart, K Wyrwich, JL Poon, P Auguste, J Zhong, and J Elkins

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Interferon-λ rs12979860 genotype and liver fibrosis in viral and non-viral chronic liver disease, Jacob George, Mohammed Eslam, Ahmed M. Hashem, Reynold Leung, Manuel Romero-Gomez, Thomas Berg, Gregory J. Dore, Henry L.K. Chan, William L. Irving, David Sheridan, Maria L. Abate, Leon A. Adams, Alessandra Mangia, Martin Weltman, Elisabetta Bugianesi, Ulrich Spengler, Olfat Shaker, Janett Fischer, Lindsay Mollison, Wendy Cheng, Elizabeth Powell, Jacob Nattermann, Stephen Riordan, Duncan McLeod, Nicola J. Armstrong, Mark W. Douglas, Christopher Liddle, David R. Booth, and Golo Ahlenstiel

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Interventions to improve antimicrobial prescribing of doctors in training: the IMPACT (IMProving Antimicrobial presCribing of doctors in Training) realist review, Geoff Wong, Nicola Brennan, Karen Mattick, Mark Pearson, Simon Briscoe, and Chrysanthi Papoutsi

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Lessons learned from recruiting socioeconomically disadvantaged smokes into a pilot randomized controlled trial to explore the role of Exercise Assisted Reduction then Stop (EARS) smoking., Tom P. Thompson, Colin J. Greaves, Richard Ayres, Paul Aveyard, Fiona C. Warren, and Richard Byng

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Long-acting muscarinic antagonist use in adults with asthma: real-life prescribing and outcomes of add-on therapy with tiotropium bromide, C King, D Price, A Kaplan, R Jones, D Freeman, A Burden, S Gould, M Ali, M Thomas, and Ziegenweidt J von

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Making a difference: an interdisciplinary social engagement project, Richard Ayres, Maria Tighe, and Sebastian Stevens

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PCSK9, apolipoprotein E and lipoviral particles in chronic hepatitis C genotype 3: Evidence for genotype-specific regulation of lipoprotein metabolism, Simon H. Bridge, David A. Sheridan, Daniel J. Felmlee, Mary M.E. Crossey, Fiona I. Fenwick, Clare V. Lanyon, Geneviève Dubuc, Nabil G. Seidah, Jean Davignon, Howard C. Thomas, Simon D. Taylor-Robinson, Geoffrey L. Toms, R. Dermot G. Neely, and Margaret F. Bassendine

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Polymorphisms Near TBX5 and GDF7 Are Associated With Increased Risk for Barrett’s Esophagus, Claire Palles, Laura Chegwidden, Xinzhong Li, John M. Findlay, Garry Farnham, Giner F Castro, Maikel P. Peppelenbosch, Michal Kovac, Claire L. Adams, Hans Prenen, Sarah Briggs, Rebecca Harrison, Scott Sanders, David Macdonald, Chris Haigh, Art Tucker, Sharon Love, Manoj Nanji, John Decaestecker, David Ferry, Barrie Rathbone, Julie Hapeshi, Hugh Barr, Paul Moayyedi, Peter Watson, Barbara Zietek, Neera Maroo, Laura Gay, Tim Underwood, Lisa Boulter, Hugh McMurtry, David Monk, Praful Patel, Krish Ragunath, Dulaimi D Al, Iain Murray, Konrad Koss, Andrew Veitch, Nigel Trudgill, Chuka Nwokolo, Bjorn Rembacken, Paul Atherfold, Elaine Elaine Green, Yeng Ang, Ernst J. Kuipers, Wu Chow, Stuart Paterson, Sudarshan Kadri, Ian Beales, Charles Grimley, Paul Mullins, Conrad Beckett, Mark Farrant, Andrew Dixon, Sean Kelly, Matthew Johnson, Shahjehan Wajed, Anjan Dhar, Elinor Sawyer, Rebecca Roylance, Lynn Onstad, Marilie D. Gammon, Douglas A. Corley, Nicholas J. Shaheen, Nigel C. Bird, Laura J. Hardie, Brian J. Reid, Weimin Ye, Geoffrey Liu, Yvonne Romero, Leslie Bernstein, Anna H. Wu, Alan G. Casson, Rebecca Fitzgerald, David C. Whiteman, Harvey A. Risch, David M. Levine, Tom L. Vaughan, Auke P. Verhaar, den Brande J van, Eelke L. Toxopeus, Manon C. Spaander, Bas P.L. Wijnhoven, der Laan LJW van, Kausilia Krishnadath, Cisca Wijmenga, Gosia Trynka, Ross McManus, John V. Reynolds, J O’Sullivan, and Padraic Macmathuna

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Predicting frequent COPD exacerbations using primary care data, D Price, M Kerkhof, D Freeman, R Jones, and A Chisholm

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Safety culture and the 5 steps to safer surgery: an intervention study, M. R. Hill, M. J. Roberts, M. L. Alderson, and T. C.E. Gale

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Serotonin stimulates secretion of exosomes from microglia cells, K Glebov, M Löchner, R Jabs, T Lau, O Merkel, P Schloss, C Steinhäuser, and J Walter

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The burden of revision sinonasal surgery in the UK—data from the Chronic Rhinosinusitis Epidemiology Study (CRES): a cross-sectional study, C Philpott, C Hopkins, S Erskine, N Kumar, A Robertson, A Farboud, S Ahmed, S Anari, R Cathcart, H Khalil, P Jervis, S Carrie, N Kara, P Prinsley, R Almeyda, N Mansell, S Sunkaraneni, M Salam, J Ray, J Panesaar, J Hobson, A Clark, and S Morris

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The H50Q Mutation Induces a 10-fold Decrease in the Solubility of α-Synuclein, John Christodoulou, Riccardo Porcari, Christos Proukakis, Christopher A. Waudby, Benedetta Bolognesi, P. Patrizia Mangione, Jack F.S. Paton, Stephen Mullin, Lisa D. Cabrita, Amanda Penco, Annalisa Relini, Guglielmo Verona, Michele Vendruscolo, Monica Stoppini, Gian Gaetano Tartaglia, Carlo Camilloni, Anthony H.V. Schapira, and Vittorio Bellotti

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The inevitable drift to triple therapy in COPD: an analysis of prescribing pathways in the UK, D Price, G Brusselle, K Gruffydd-Jones, M Miravitlles, R Stewart, M Baldwin, D Keininger, and R Jones

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The London Exercise And Pregnant smokers (LEAP) trial: a randomised controlled trial of physical activity for smoking cessation in pregnancy with an economic evaluation, Michael Ussher, S Lewis, Paul Aveyard, Isaac Manyonda, Robert West, B Lewis, Bess Marcus, Muhammad Riaz, Adrian H. Taylor, Pelham Barton, Amanda Daley, Holly Essex, Dale Esliger, and Tim Coleman

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The Use of Virtual Patients to Promote Inter-professional Learning for Medical and Dental Students, Hisham Khalil, Arunangsu Chatterjee, Ruth Endacott, Mel Joyner, and Mahrukh Mirza

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Visualizing peripheral nerve regeneration by whole mount staining., Xin Peng Dun and David B. Parkinson

Submissions from 2014

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Adherence in multiple sclerosis (ADAMS): Classification, relevance, and research needs. A meeting report, C Heesen, J Bruce, P Feys, J Sastre-Garriga, and et al

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Artesunate induces necrotic cell death in schwannoma cells., S. Luo, R. W. Button, F. Lin, E. Ercolano, J. H. Vincent, B. Hu, and C. O. Hanemann

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Probing auditory scene analysis, S Deike, SL Denham, and E Sussman

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Evaluating the application of research-based guidance to the design of an emergency preparedness leaflet, E Hellier, J Edworthy, L Newbold, and et al

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Study protocol for a double blind, randomised, placebo-controlled trial of continuous subpectoral local anaesthetic infusion for pain and shoulder function following mastectomy: SUB-pectoral Local anaesthetic Infusion following MastEctomy (SUBLIME) study, R Langford, I Brown, J Vickery, and et al

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Modelling the impact of improving screening and treatment of chronic hepatitis C virus infection on future hepatocellular carcinoma rates and liver-related mortality., Steven D. Ryder, Matthew E. Cramp, William M. Rosenberg, Sarah Blach, and Julie Parkes

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A written self-help intervention for depressed adults comparing behavioural activation combined with physical activity promotion with a self-help intervention based upon behavioural activation alone: study protocol for a parallel group pilot randomised controlled trial (BAcPAc)., Paul Farrand, Claire Pentecost, Colin Greaves, RS Taylor, Fiona Warren, Colin Green, Melvyn Hillsdon, Phil Evans, Jo Welsman, and AH Taylor

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Syndecan 4 Is Involved in Mediating HCV Entry through Interaction with Lipoviral Particle-Associated Apolipoprotein E, Mathieu Lefèvre, Daniel J. Felmlee, Marie Parnot, Thomas F. Baumert, and Catherine Schuster

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Question design in nurse-led and GP-led telephone triage for same-day appointment requests: a comparative investigation, J Pooler, J Murdoch, R Barnes, and et al

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Randomised Evaluation of modified Valsalva Effectiveness in Re-entrant Tachycardias (REVERT) study, A Appelboam, A Reuben, C Mann, T Lobban, and et al

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Drosophila Embryos as Model to Assess Cellular and Developmental Toxicity of Multi-Walled Carbon Nanotubes (MWCNT) in Living Organisms, Boyin Liu, Eva M. Campo, and Torsten Bossing

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Axl/Gas6/NFκB signalling in schwannoma pathological proliferation, adhesion and survival., S. Ammoun, L. Provenzano, L. Zhou, M. Barczyk, K. Evans, D. A. Hilton, S. Hafizi, and C. O. Hanemann

Architecture and Expression of the Nfatc1 Gene in Lymphocytes, Edgar Serfling, Ronald Rudolf, Rhoda Busch, Amiya K. Patra, Khalid Muhammad, Andris Avots, Jean Christophe Andrau, and Stefan Klein-Hessling

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Deficiency of Sphingosine-1-phosphate Lyase Impairs Lysosomal Metabolism of the Amyloid Precursor Protein, I Karaca, IY Tamboli, K Glebov, J Richter, LH Fell, MO Grimm, VJ Haupenthal, T Hartmann, MH Gräler, Echten-Deckert G van, and J Walter

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Development of a prototype lateral flow immunoassay (LFI) for the rapid diagnosis of melioidosis., Raymond L. Houghton, Dana E. Reed, Mark A. Hubbard, Michael J. Dillon, Hongjing Chen, Bart J. Currie, Mark Mayo, Derek S. Sarovich, Vanessa Theobald, Direk Limmathurotsakul, Gumphol Wongsuvan, Narisara Chantratita, Sharon J. Peacock, Alex R. Hoffmaster, Brea Duval, Paul J. Brett, Mary N. Burtnick, and David P. AuCoin

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Exploring perceived barriers, drivers, impacts and the need for evaluation of public involvement in health and social care research: a modified Delphi study, Ann Jacoby, D. Snape, J. Kirkham, N. Britten, K. Froggatt, F. Gradinger, F. Lobban, Jennie Popay, and K. Wyatt

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Interplay between phosphorylation and palmitoylation mediates plasma membrane targeting and sorting of GAP43, A Gauthier-Kemper, M Igaev, F Sündermann, D Janning, J Brühmann, K Moschner, H-J Reyher, W Junge, K Glebov, J Walter, L Bakota, and R Brandt

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Longitudinal evaluation of quality of life in 288 patients with neurofibromatosis 2, Rosalie E. Ferner, Adam Shaw, D. Gareth Evans, Dympna McAleer, Dorothy Halliday, Allyson Parry, F. Lucy Raymond, Juliette Durie-Gair, C. Oliver Hanemann, Rachel Hornigold, Patrick Axon, and John F. Golding

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Mechanisms underlying dual effects of serotonin during development of Helisoma trivolvis(Mollusca), K Glebov, EE Voronezhskaya, MY Khabarova, E Ivashkin, LP Nezlin, and EG Ponimaskin

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Qualified doctor and medical students' use of resources for accessing information: what is used and why?, Karen Mattick, Nicola Brennan, Sarah Edwards, Narcie Kelly, Alice Miller, and Lucy Harrower

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Self-regulating smoking and snacking through physical activity., Adrian H. Taylor and Hwajung Oh

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Understanding how appraisal of doctors produces its effects: a realist review protocol, Julian Archer, Nicola Brennan, Marie Bryce, Mark Pearson, Geoff Wong, and Chris Cooper

Update to the study protocol for a randomized controlled trial comparing mindfulness-based cognitive therapy with maintenance anti-depressant treatment depressive relapse/recurrence: the PREVENT trial, Willem Kuyken, Sarah Byford, Richard Byng, Tim Dalgleish, Glyn Lewis, Rod Taylor, Edward R. Watkins, Rachel Hayes, Paul Lanham, David Kessler, Nicola Morant, and Alison Evans

Submissions from 2013

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Bayesian methods to determine performance differences and to quantify variability among centers in multi-center trials: the IHAST trial, EO Bayman, KM Chaloner, BJ Hindman, MM Todd, and IHAST investigators

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GPAQ-R: development and psychometric properties of a version of the General Practice Assessment Questionnaire for use for revalidation by general practitioners in the UK, M Roland, M Roberts, V Rhenius, and J Campbell

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The implementation of NICE guidance on venous thromboembolism risk assessment and prophylaxis: A before- after observational study to assess the impact on patient safety across four hospitals in England., A Bateman, WR Sheaff, S Child, O Boiko, OC Ukoumunne, T Nokes, A Copplestone, and C Gericke

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Neratinib overcomes trastuzumab resistance in HER2 amplified breast cancer, A Canonici, M Gijsen, M Mullooly, R Bennett, and et al

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Sorafenib for advanced hepatocellular carcinoma (HCC): impact of rationing in the United Kingdom, DH Palmer, SA Hussain, AJ Smith, S Hargreaves, and et al

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A pilot randomised controlled trial of a preconsultation web-based intervention to improve the care quality and clinical outcomes of diabetes outpatients (DIAT)., Julia Frost, Rob Anderson, Catherine Argyle, Mark Daly, Faith Harris-Golesworthy, Jim Harris, Andy Gibson, Wendy Ingram, Jon Pinkney, Obioha C. Ukoumunne, Bijay Vaidya, Jane Vickery, and Nicky Britten

The Prevalence of Frontal Cells and Their Relation to Frontal Sinusitis: A Radiological Study of the Frontal Recess Area, AZ Eweiss and HS Khalil

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Factors affecting patients' trust and confidence in GPs: evidence from the English national GP patient survey., Joanne E. Croker, Dawn R. Swancutt, Martin J. Roberts, Gary A. Abel, Martin Roland, and John L. Campbell

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Hepatitis C Virus, Cholesterol and Lipoproteins — Impact for the Viral Life Cycle and Pathogenesis of Liver Disease, Daniel J. Felmlee, Mohamed Lamine Hafirassou, Mathieu Lefevre, Thomas F. Baumert, and Catherine Schuster

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How managed a market? Modes of commissioning in England and Germany, Rod Sheaff, Naomi Chambers, Nigel Charles, Mark Exworthy, Ann Mahon, Richard Byng, and Russell Mannion

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The practice of commissioning healthcare from a private provider: learning from an in-depth case study, N Chambers, WR Sheaff, A Mahon, R Byng, R Mannion, N Charles, M Exworthy, and S Llewllyn

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Effectiveness of a motivational interviewing intervention on weight loss, physical activity and cardiovascular disease risk factors: a randomised controlled trial with a 12-month post-intervention follow-up., Sarah J. Hardcastle, Adrian H. Taylor, Martin P. Bailey, Robert A. Harley, and Martin S. Hagger

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Has incentive payment improved venous thrombo-embolism risk assessment and treatment of hospital in-patients?, Sue Child, Rod Sheaff, Olga Boiko, Alice Bateman, and Christian A. Gericke

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Critical appraisal of axitinib in the treatment of advanced renal cell carcinoma, J Ansari, SA Hussain, J Glaholm, and A Ansari

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A brisk walk, compared with being sedentary, reduces attentional bias and chocolate cravings among regular chocolate eaters with different body mass., Adrian H. Taylor and Hwajung Oh

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Acute effect of exercise on alcohol urges and attentional bias towards alcohol related images in high alcohol consumers, Adrian H. Taylor, Hwajung Oh, and Sarah Cullen

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An educational framework for managing and supporting medication adherence in Europe, S White, W Clyne, and C Mshelia

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A systematic review of educational interventions to change behaviour of prescribers in hospital settings, with a particular emphasis on new prescribers., Nicola Brennan and Karen Mattick

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Delivery and use of individualised feedback in large class medical teaching, SA Burr, E Brodier, and S Wilkinson

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Evidence-based programs in children's services: A critical appraisal, Nick Axford and Louise Morpeth

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Exercise referral for drug users aged 40 and over: results of a pilot study in the UK, Caryl M. Beynon, Amy Luxton, Rhiannon Whitaker, N. Tim Cable, Lucy Frith, Adrian H. Taylor, Lu Zou, Peter Angell, Scott Robinson, D Holland, S Holland, and Mark Gabbay

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Loss of SOX10 function contributes to the phenotype of human Merlin-null schwannoma cells., David B. Parkinson, Robin D.S. Doddrell, Xin Peng Dun, Aditya Shivane, M. Laura Feltri, Lawrence Wrabetz, Michael Wegner, Elisabeth Sock, and C. Oliver Hanemann

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Molecular genetic studies of neurodegenerative disease., T Cooke, C Carroll, J Zajicek, S Ellard, and K Morrison

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PAin SoluTions In the Emergency Setting (PASTIES); a protocol for two open-label randomised trials of patient-controlled analgesia (PCA) versus routine care in the emergency department, JE Smith, M Rockett, R Squire, CJ Hayward, and et al