Browse research from the Peninsula Medical School.

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Submissions from 2020

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Cardiopulmonary exercise testing and cardiopulmonary morbidity in patients undergoing major head and neck surgery, B. B. Lalabekyan, N. Tetlow, R. Moonesinghe, D. Martin, E. Burdett, J. Otto, D. Wyndham, E. Bettini, N. Kalavrezos, and R. C.M. Stephens

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A novel method for assessing design fidelity in web-based behavioral interventions., Jeffrey D. Lambert, Lewis R. Elliott, Adrian H. Taylor, Paul Farrand, Anne M. Haase, and Colin J. Greaves

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Hospital readmission among people experiencing homelessness in England: a cohort study of 2772 matched homeless and housed inpatients, Dan Lewer, Dee Menezes, Michelle Cornes, Ruth M. Blackburn, Richard Byng, Michael Clark, Spiros Denaxas, Hannah Evans, James Fuller, Nigel Hewett, Alan Kilmister, Serena April Luchenski, Jill Manthorpe, Martin McKee, Joanne Neale, Alistair Story, Michela Tinelli, Martin Whiteford, Fatima Wurie, Alexei Yavlinsky, Andrew Hayward, and Robert Aldridge

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Clinical features and genetic risk of demyelination following anti-TNF treatment, Simeng Lin, Harry D. Green, Peter Hendy, Neel M. Heerasing, Neil Chanchlani, Benjamin Hamilton, Gareth J. Walker, Graham A. Heap, Jeremy Hobart, Roswell J. Martin, Alasdair J. Coles, Peter M. Irving, Guy Chung-Faye, J. R.Fraser Cummings, Ellina Lytvyak, Vibeke Andersen, Andrew R. Wood, Jessica Tyrrell, Robin N. Beaumont, Michael N. Weedon, Nicholas A. Kennedy, Alexander Spiers, Timothy Harrower, James R. Goodhand, and Tariq Ahmad

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The Potential of MLN3651 in Combination with Selumetinib as a Treatment for Merlin-Deficient Meningioma, Rimmer J. Lyons, Emanuela Ercolano, Daniele Baiz, Mahindra Makhija, Allison Berger, Todd Sells, Steve Stroud, David Hilton, Claire L. Adams, and C. Oliver Hanemann

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Randomised clinical trial: palliative long-term abdominal drains vs large-volume paracentesis in refractory ascites due to cirrhosis, Lucia Macken, Stephen Bremner, Heather Gage, Morro Touray, Peter Williams, David Crook, Louise Mason, Debbie Lambert, Catherine J. Evans, Max Cooper, Jean Timeyin, Shani Steer, Mark Austin, Nick Parnell, Sam J. Thomson, David Sheridan, Mark Wright, Peter Isaacs, Ahmed Hashim, and Sumita Verma

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Letter: long-term abdominal drains in refractory ascites-evolving concept of palliative care in decompensated cirrhosis. Authors' reply, Lucia Macken, Stephen Bremner, David Sheridan, and Sumita Verma

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Development of a Clinical Decision Rule for the Early Safe Discharge of Patients with Mild Traumatic Brain Injury and Findings on Computed Tomography Brain Scan: A Retrospective Cohort Study, Carl Marincowitz, Fiona E. Lecky, Victoria Allgar, Peter Hutchinson, Hadir Elbeltagi, Faye Johnson, Eimhear Quinn, Silvia Tarantino, Will Townend, Angelos G. Kolias, and Trevor A. Sheldon

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DLG5 variants are associated with multiple congenital anomalies including ciliopathy phenotypes, Jonathan Marquez, Nina Mann, Kathya Arana, Engin Deniz, Weizhen Ji, Monica Konstantino, Emily K. Mis, Charu Deshpande, Lauren Jeffries, Julie McGlynn, Hannah Hugo, Eugen Widmeier, Martin Konrad, Velibor Tasic, Raffaella Morotti, Julia Baptista, Sian Ellard, Saquib Ali Lakhani, Friedhelm Hildebrandt, and Mustafa K. Khokha

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After the fire: Post-pandemic reflections, Daniel Martin

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COVID-19: An update from England’s high consequence infectious diseases intensive care unit leads, Daniel Martin, Sarah Platt, Peter Hampshire, and Chris Meadows

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Perioperative Quality Initiative (POQI) consensus statement on fundamental concepts in perioperative fluid management: fluid responsiveness and venous capacitance, GS Martin, DA Kaufman, PE Marik, NI Shapiro, DZH Levett, J Whittle, DB MacLeod, D Chappell, J Lacey, T Woodcock, K Mitchell, MLNG Malbrain, TM Woodcock, D Martin, CHE Imray, MW Manning, H Howe, MPW Grocott, MG Mythen, TJ Gan, and TE Miller

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Human adaptation to hypoxia in critical illness, Helen T. McKenna, Andrew J. Murray, and Daniel S. Martin

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Migrating Schwann cells direct axon regeneration within the peripheral nerve bridge, Qing Min, David B. Parkinson, and Xin Peng Dun

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COVID-19: UK frontline intensivists' emerging learning, Hugh Montgomery, Niran Rehill, Luigi Camporota, Nicki Credland, Mike Grocott, Mark Hamilton, Daniel Martin, Brijesh Patel, Ganesh Suntharalingam, Tamas Szakmany, Shahana Uddin, Andre Vercueil, and Mike Roberts

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Brain Microglial Activation Increased in Glucocerebrosidase ( GBA ) Mutation Carriers without Parkinson's disease, Stephen Mullin, Morten Gersel Stokholm, Derralyn Hughes, Atul Mehta, Peter Parbo, Rainer Hinz, Nicola Pavese, David J. Brooks, and Anthony H.V. Schapira

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GATA-4, a potential novel therapeutic target for high-grade meningioma, regulates miR-497, a potential novel circulating biomarker for high-grade meningioma, Caterina Negroni, David A. Hilton, Emanuela Ercolano, Claire L. Adams, Kathreena M. Kurian, Daniele Baiz, and C. Oliver Hanemann

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Smartphone-based optical assays in the food safety field, J. L.D. Nelis, A. S. Tsagkaris, M. J. Dillon, J. Hajslova, and C. T. Elliott

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How healthcare systems shape a purchaser’s strategies and actions when managing chronic care, Bart A.C. Noort, Kees Ahaus, der Vaart T van, Naomi Chambers, and Rod Sheaff

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British Obesity and Metabolic Surgery Society Guidelines on perioperative and postoperative biochemical monitoring and micronutrient replacement for patients undergoing bariatric surgery—2020 update, Mary O'Kane, Helen M. Parretti, Jonathan Pinkney, Richard Welbourn, Carly A. Hughes, Jessica Mok, Nerissa Walker, Denise Thomas, Jennifer Devin, Karen D. Coulman, Gail Pinnock, Rachel L. Batterham, Kamal K. Mahawar, Manisha Sharma, Alex I. Blakemore, Iris McMillan, and Julian H. Barth

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Effects of perioperative oxygen concentration on oxidative stress in adult surgical patients: a systematic review, Alexander H. Oldman, Daniel S. Martin, Martin Feelisch, Michael P.W. Grocott, and Andrew F. Cumpstey

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An anaesthetic and intensive care perspective on infection control measures for the prevention of airborne transmission of SARS-CoV-2, HR O'Mahony and Daniel S. Martin

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Reply to Tasker and to Lellouche and L’Her, Edward Palmer, Daniel Martin, Mervyn Singer, and Steve Harris

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HuR/ELAVL1 drives malignant peripheral nerve sheath tumor growth and metastasis, Marta Palomo-Irigoyen, Encarni Pérez-Andrés, Marta Iruarrizaga-Lejarreta, Adrián Barreira-Manrique, Miguel Tamayo-Caro, Laura Vila-Vecilla, Leire Moreno-Cugnon, Nagore Beitia, Daniela Medrano, David Fernández-Ramos, Juan José Lozano, Satoshi Okawa, José L. Lavín, Natalia Martín-Martín, James D. Sutherland, Juan VG de, Monika Gonzalez-Lopez, Nuria Macías-Cámara, David Mosén-Ansorena, Liyam Laraba, CO Hanemann, Emanuela Ercolano, David B. Parkinson, Christopher W. Schultz, Marcos J. Araúzo-Bravo, Alex M. Ascensión, Daniela Gerovska, Haizea Iribar, Ander Izeta, Peter Pytel, Philipp Krastel, Alessandro Provenzani, Pierfausto Seneci, Ruben D. Carrasco, Sol A Del, María Luz Martinez-Chantar, Rosa Barrio, Eduard Serra, Conxi Lazaro, Adrienne M. Flanagan, Myriam Gorospe, Nancy Ratner, Ana M. Aransay, Arkaitz Carracedo, Marta Varela-Rey, and Ashwin Woodhoo

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Barriers and facilitators to GP–patient communication about emotional concerns in UK primary care: a systematic review, Daisy Parker, Richard Byng, Chris Dickens, Debbie Kinsey, and Rose McCabe

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Patients’ experiences of seeking help for emotional concerns in primary care: doctor as drug, detective and collaborator, Daisy Parker, Richard Byng, Chris Dickens, and Rose McCabe

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Oxygenation of the critically ill in selected intensive care units in the UK: are we usual?, Benjamin Post, Edward Palmer, Steve Harris, Mervyn Singer, and Daniel Martin

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Remediation programmes for practising doctors to restore patient safety: the RESTORE realist review, T Price, N Brennan, G Wong, L Withers, J Cleland, A Wanner, T Gale, L Prescott-Clements, J Archer, and M Bryce

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Reviving clinical governance? A qualitative study of the impact of professional regulatory reform on clinical governance in healthcare organisations in England, Tristan Price, John Tredinnick-Rowe, Kieran Walshe, Abigail Tazzyman, Jane Ferguson, Alan Boyd, Julian Archer, and Marie Bryce

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Admission Decision-Making in Hospital Emergency Departments: The Role of the Accompanying Person, Susanna Rance, Debra Westlake, Heather Brant, Ingrid Holme, Ruth Endacott, Jonathan Pinkney, and Richard Byng

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Rationing bytes: managing demand for digital forensic examinations, Brian Rappert, Hannah Wheat, and Dana Wilson-Kovacs

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The Use of Tranexamic Acid to Reduce the Need for Nasal Packing in Epistaxis (NoPAC): Randomized Controlled Trial, Adam Reuben, Andrew Appelboam, Kara N. Stevens, Jane Vickery, Paul Ewings, Wendy Ingram, Alison N. Jeffery, Richard Body, Malcolm Hilton, Jason Coppell, Brian Wainman, and Andy Barton

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Research with older people in a world with COVID-19: identification of current and future priorities, challenges and opportunities, Sarah J. Richardson, Camille B. Carroll, Jacqueline Close, Adam L. Gordon, J O'Brien, Terence J. Quinn, Lynn Rochester, Avan A. Sayer, Susan D. Shenkin, der Velde N van, Jean Woo, and Miles D. Witham

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Assessment of patients with lower urinary tract symptoms where an undiagnosed neurological disease is suspected: A report from an International Continence Society consensus working group, Holly A. Roy, Jeremy Nettleton, Camilla Blain, Catherine Dalton, Bilal Farhan, Ailton Fernandes, Petros Georgopoulos, Sabine Klepsch, John Lavelle, Evangelista Martinelli, Jalesh N. Panicker, Ivan Radoja, Christina Anastasia Rapidi, e Silva R Pereira, Katarina Tudor, Adrian S. Wagg, and Marcus J. Drake

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Leadership in Dental Practice: a Three Stage Systematic Review and Narrative Synthesis, H Sally, Debby Cotton, and Lucy Spowart

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State of the Art and Future Challenges in Multiple Sclerosis Research and Medical Management: An Insight into the 5th International Porto Congress of Multiple Sclerosis, María José Sá, dos Reis R Soares, Ayse Altintas, Elisabeth Gulowsen Celius, Claudia Chien, Giancarlo Comi, Francesc Graus, Jan Hillert, Jeremy Hobart, Gulfaraz Khan, Najib Kissani, Dawn Langdon, Maria Isabel Leite, Darin T. Okuda, Jacqueline Palace, Regina María Papais-Alvarenga, Inês Mendes-Pinto, and Fu Dong Shi

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Implementing large-system, value-based healthcare initiatives: a realist study protocol for seven natural experiments, Mitchell N. Sarkies, Emilie Francis-Auton, Janet C. Long, Andrew Partington, Chiara Pomare, Hoa Mi Nguyen, Wendy Wu, Johanna Westbrook, Richard O. Day, Jean Frederic Levesque, Rebecca Mitchell, Frances Rapport, Henry Cutler, Yvonne Tran, Robyn Clay-Williams, Diane E. Watson, Gaston Arnolda, Peter D. Hibbert, Reidar Lystad, Virginia Mumford, George Leipnik, Kim Sutherland, Rebecca Hardwick, and Jeffrey Braithwaite

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Defining the characteristics of intermediate care models including transitional care: an international Delphi study, Duygu Sezgin, Rónán O’Caoimh, Mark R. O’Donovan, Mohamed A. Salem, Siobhán Kennelly, Luz Lopez Samaniego, Cristina Arnal Carda, Rafael Rodriguez-Acuña, Marco Inzitari, Teija Hammar, Claire Holditch, Janet Prvu Bettger, Martin Vernon, Áine Carroll, Felix Gradinger, Gaston Perman, Martin Wilson, Antoine Vella, Antonio Cherubini, Helen Tucker, Maria Pia Fantini, Graziano Onder, Regina Roller-Wirnsberger, Luis Miguel Gutiérrez-Robledo, Matteo Cesari, Paula Bertoluci, Magdalena Kieliszek, der Vlegel-Brouwer W van, Michelle Nelson, Leocadio Rodríguez Mañas, Eleftheria Antoniadou, François Barriere, Sebastian Lindblom, Grace Park, Isidoro Pérez, Dolores Alguacil, Douglas Lowdon, Maria Eugenia Alkiza, Cristina Alonso Bouzon, John Young, Ana Carriazo, Aaron Liew, and Anne Hendry

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Book Review: Microeconomics: A Critical Companion by Ben Fine, R Sheaff

Ben Fine. Micro-economics. A Critical Companion. London 2016 (Pluto), W Sheaff

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Remimazolam; a role for anaesthesia/ sedation?, J Sneyd and A Rigby-Jones

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The alien world of reflective practice: A non-fictional ‘tale’ of academics’ experiences of applying for Senior Fellowship, Lucy Spowart and Rebecca Turner

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Implementation of the ‘TAKE STOCK’ Hot Debrief Tool in the ED: a quality improvement project, Max Sugarman, Blair Graham, Sarah Langston, Pam Nelmes, and John Matthews

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Knowledge, skills and attitudes of older people and staff about getting up from the floor following a fall: a qualitative investigation, Dawn R. Swancutt, Suzy V. Hope, Benjamin P. Kent, Maria Robinson, and Victoria A. Goodwin

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Improvements in pain, medication use and quality of life in onabotulinumtoxinA-resistant chronic migraine patients following erenumab treatment – real world outcomes, J Talbot, R Stuckey, L Crawford, S Weatherby, and S Mullin

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Effect of zinc treatment on clinical outcomes in patients with liver cirrhosis: A systematic review and meta-analysis, HK Tan, A Streeter, ME Cramp, and AD Dhanda

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Effect of zinc treatment on clinical outcomes in patients with liver cirrhosis: A systematic review and meta-analysis, Huey K. Tan, Adam Streeter, Matthew E. Cramp, and Ashwin D. Dhanda

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Oxidative stress in alcohol-related liver disease, Huey K. Tan, Euan Yates, Kristen Lilly, and Ashwin D. Dhanda

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Editorial: ‘Do we really need another review on the effects of physical activity on alcohol and other drug use disorders?’, Adrian H. Taylor, Tom P. Thompson, and Jane Horrell

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Randomised controlled trial of tailored support to increase physical activity and reduce smoking in smokers not immediately ready to quit: protocol for the Trial of physical Activity-assisted Reduction of Smoking (TARS) Study, Adrian Taylor, Tom P. Thompson, Michael Ussher, Paul Aveyard, Rachael L. Murray, Tess Harris, Siobhan Creanor, Colin Green, Adam Justin Streeter, Jade Chynoweth, Wendy Ingram, Colin J. Greaves, Helen Hancocks, Tristan Snowsill, Lynne Callaghan, Lisa Price, Jane Horrell, Jennie King, Alex Gude, Mary George, Charlotte Wahlich, Louisa Hamilton, Kelisha Cheema, Sarah Campbell, and Dan Preece

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A multi-centre Trial of physical Activity assisted Reduction of Smoking (TARS): Baseline characteristics, and health trainer led intervention engagement, A Taylor, A Streeter, T Thompson, S Creanor, W Ingram, P Aveyard, M Ussher, T Harris, R Murray, C Greaves, C Green, and J Chynoweth

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Randomised controlled trial of an augmented exercise referral scheme using web-based behavioural support for inactive adults with chronic health conditions: the e-coachER trial., A Taylor, RS Taylor, W Ingram, SG Dean, K Jolly, N Mutrie, J Lambert, L Yardley, A Streeter, C Greaves, C McAdam, L Price, NK Anokye, and J Campbell

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An engaged approach to exploring issues around poverty and mental health: A reflective evaluation of the research process from researchers and community partners involved in the DeStress study, Felicity Thomas, Lorraine Hansford, Katrina Wyatt, Richard Byng, Karen Coombes, Jenna Finch, Kirsty Finnerty, Joe Ford, K Guppy, R Guppy, Susanne Hughes, Rose McCabe, Hilary Richardson, Debbie Roche, and Hazel Stuteley

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Physical activity and the prevention, reduction, and treatment of alcohol and other drug use across the lifespan (The PHASE review): A systematic review, T. P. Thompson, J. Horrell, A. H. Taylor, A. Wanner, K. Husk, Y. Wei, S. Creanor, R. Kandiyali, J. Neale, J. Sinclair, M. Nasser, and G. Wallace

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Clinical characteristics and outcomes of critically ill patients with COVID-19 admitted to an intensive care unit in London: A prospective observational cohort study, Ross J. Thomson, Jennifer Hunter, Jonathan Dutton, James Schneider, Maryam Khosravi, Alisha Casement, Kulwant Dhadwal, and Daniel Martin

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Recovery from recurrent depression with mindfulness-based cognitive therapy and antidepressants: a qualitative study with illustrative case studies, Alice Tickell, Richard Byng, Catherine Crane, Felix Gradinger, Rachel Hayes, James Robson, Jessica Cardy, Alice Weaver, Nicola Morant, and Willem Kuyken

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β-Cell Glucose Sensitivity determines hyperglycaemia in Polycystic Ovary Syndrome, J Tomlinson, A Mari, A Tura, K Bond, E Stenhouse, T Dew, RP Vincent, and J Pinkney

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An audit of emotional logic for mental health self-care improving social connection, Abigail Turton, Marian Langsford, Lorenzo D Di, Daniel Zahra, Julie Henshelwood, and Trevor Griffiths

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Open letter from UK based academic scientists to the secretaries of state for digital, culture, media and sport and for health and social care regarding the need for independent funding for the prevention and treatment of gambling harms, Heather Wardle, James Banks, Paul Bebbington, Lindsey Blank, Jones OBE H Bowden, Stephanie Bramley, Christopher Bunn, Emma Casey, Rebecca Cassidy, Samuel R. Chamberlain, James Close, Nathan Critchlow, Fiona Dobbie, Carolyn Downs, Simon Dymond, Emanuele Fino, Elizabeth Goyder, Cindy Gray, Mark Griffiths, Peter Grindrod, Lee Hogan, Alice Hoon, Kate Hunt, Richard James, Bev John, Jill Manthorpe, Jim McCambridge, David McDaid, Martin McKee, Sally McManus, Antony Moss, Caroline Norrie, David J. Nutt, Jim Orford, Rob Pryce, Richard Purves, Gerda Reith, A Roberts, E Roberts, Gareth Roderique-Davies, J Rogers, RD Rogers, Stephen Sharman, John Strang, Richard Tunney, John Turner, Robert West, and David Zendle

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Glucocorticoid treatment in patients with newly diagnosed immune thrombocytopenia switches CD14 ++ CD16 + intermediate monocytes from a pro‐inflammatory to an anti‐inflammatory phenotype, Emily L. Williams, Madeleine L. Stimpson, Philippa J.P. Lait, LP Schewitz‐Bowers, Lauren V. Jones, Ashwin D. Dhanda, Richard W.J. Lee, and Charlotte A. Bradbury

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Genome-wide association study of pain in Parkinson's disease implicates TRPM8 as a risk factor, Nigel M. Williams, Leon Hubbard, Cynthia Sandor, Caleb Webber, Hannah Hendry, Camille Carroll, Michael Lawton, K. Ray Chaudhuri, Huw Morris, Michele T. Hu, Donald G. Grosset, Christopher Kobylecki, and Monty Silverdale

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Ensuring that COVID-19 Research is Inclusive - guidance from the NIHR INCLUDE project, Miles D. Witham, Eleanor Anderson, Camille B. Carroll, Paul M. Dark, Kim Down, Alistair S. Hall, Joanna Knee, Eamonn R. Maher, Rebecca H. Maier, Gail A. Mountain, Gary Nestor, JT O’Brien, Laurie Oliva, James Wason, and Lynn Rochester

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Developing a roadmap to improve trial delivery for underserved groups: results from a UK multi-stakeholder process, Miles D. Witham, Eleanor Anderson, Camille Carroll, Paul M. Dark, Kim Down, Alistair S. Hall, Joanna Knee, Rebecca H. Maier, Gail A. Mountain, Gary Nestor, Laurie Oliva, Sarah R. Prowse, Amanda Tortice, James Wason, and Lynn Rochester

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The gender gap in European neurosurgical conference presentations, Julie Woodfield, Phillip Correia Copley, Mark Hughes, and Ellie Edlmann

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A large population-based study of the mental health and wellbeing of children and young people in the North of England, Barry Wright, Megan Garside, Victoria Allgar, Rachel Hodkinson, and Helen Thorpe

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Measuring quality of life in ALS/MND: validation of the WHOQOL-BREF, Carolyn A. Young, Roger Mills, Ammar Al-Chalabi, Georgina Burke, Siddharthan Chandran, David J. Dick, John Ealing, C. Oliver Hanemann, Timothy Harrower, Christopher J. Mcdermott, Tahir Majeed, Ashwin Pinto, Kevin Talbot, Jannette Walsh, Timothy L. Williams, and Alan Tennant

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Conservative or liberal oxygen therapy in adults after cardiac arrest, Paul J. Young, Michael Bailey, Rinaldo Bellomo, Stephen Bernard, Janet Bray, Pekka Jakkula, Markku Kuisma, Diane Mackle, Daniel Martin, Jerry P. Nolan, Rakshit Panwar, Matti Reinikainen, Markus B. Skrifvars, and Matt Thomas

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Feasibility of school students Skyping care home residents to reduce loneliness, Sonam Zamir, Catherine Hagan Hennessy, Adrian Haffner Taylor, and Ray Brian Jones

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Intergroup ‘Skype’ Quiz Sessions in Care Homes to Reduce Loneliness and Social Isolation in Older People, Sonam Zamir, Catherine Hennessy, Adrian Taylor, and Ray Jones

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Is It Possible to Conduct a Multi-Arm Multi-Stage Platform Trial in Parkinson’s Disease: Lessons Learned from Other Neurodegenerative Disorders and Cancer, Marie Louise Zeissler, Vivien Li, Mahesh K.B. Parmar, and Camille Buchholz Carroll

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Using a Delphi process to inform the design of disease modifying trials in Parkinson's disease, M Zeissler, R Windle, K McFarthing, K Raphael, G Rafaloff, and C Carroll

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Efficacy and Safety of Alemtuzumab Through 9 Years of Follow-up in Patients with Highly Active Disease: Post Hoc Analysis of CARE-MS I and II Patients in the TOPAZ Extension Study, Tjalf Ziemssen, Ann D. Bass, Regina Berkovich, Giancarlo Comi, Sara Eichau, Jeremy Hobart, Samuel F. Hunter, Christopher LaGanke, Volker Limmroth, Daniel Pelletier, Carlo Pozzilli, Sven Schippling, Livia Sousa, Anthony Traboulsee, Bernard M.J. Uitdehaag, Wijmeersch B Van, Zia Choudhry, Nadia Daizadeh, and Barry A. Singer

Submissions from 2019

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Causes of death among homeless people: a population-based cross-sectional study of linked hospitalisation and mortality data in England., Robert W. Aldridge, Dee Menezes, Dan Lewer, Michelle Cornes, Hannah Evans, Ruth M. Blackburn, Richard Byng, Michael Clark, Spiros Denaxas, James Fuller, Nigel Hewett, Alan Kilmister, Serena Luchenski, Jill Manthorpe, Martin McKee, Joanne Neale, Alistair Story, Michela Tinelli, Martin Whiteford, Fatima Wurie, and Andrew Hayward

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Statistical analysis plan for the Dex-CSDH trial: a randomised, double-blind, placebo-controlled trial of a 2-week course of dexamethasone for adult patients with a symptomatic chronic subdural haematoma, Annabel Allison, Ellie Edlmann, Angelos G. Kolias, Carol Davis-Wilkie, Harry Mee, Eric P. Thelin, Carole Turner, Peter J. Hutchinson, and Simon Bond

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Characterization of the urinary metabolic profile of cholangiocarcinoma in a United Kingdom population, M Alsaleh, T Barbera, H Reeves, M Cramp, S Ryder, H Gabra, K Nash, Y-L Shen, E Holmes, R Williams, and S Taylor-Robinson

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Global health competencies in UK postgraduate medical training: a scoping review and curricular content analysis, Nader Al-Shakarchi, Lucy Obolensky, Sarah Walpole, Harry Hemingway, and Amitava Banerjee

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Evaluating the recruitment process into UK anaesthesia core training: a national data linkage study of doctors’ performance at selection and subsequent postgraduate training, Margaret Aslet, Lewis W. Paton, Thomas Gale, and Paul A. Tiffin

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Does a social prescribing ‘holistic’ link-worker for older people with complex, multi-morbidity improve well-being and frailty and reduce health and social care use and costs? A 12-month before and after evaluation, Sheena Asthana, Julian Elston, Felix Gradinger, Richard Byng, Caroline Lilley-Woolnough, Sue Wroe, and Helen Harman

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Why does the NHS struggle to adopt eHealth innovations? A review of macro, meso and micro factors, Sheena Asthana, Ray Jones, and Rod Sheaff

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Improving the Early Learning of Children Growing Up in Poverty: A Rapid Review of the Evidence, N Axford and B Albers

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How Can Schools Support Parents' Engagement in their Children's Learning? Evidence from Research and Practice, N Axford, V Berry, J Lloyd, D Moore, M Rogers, A Hurst, K Blockley, H Durkin, and J Minton

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Comparing psychiatric care experiences shared online with validated questionnaires; do they include the same content?, Rebecca Baines, John Donovan, de Bere S Regan, Julian Archer, and Ray Jones

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Is collecting patient feedback 'a futile exercise' in the context of recertification?, Rebecca Baines, Daniel Zahra, Marie Bryce, de Bere S Regan, Martin Roberts, and Julian Archer

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The impact of patient complaints and compliments on medical performance: a systematic review, R Baines, T Price, J Archer, and M Bryce

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Using interpersonal process recall to understand empowerment processes in a collaborative care intervention for people with a diagnosis of psychosis, Elina Baker, Ruth Gwernan-Jones, Nicky Britten, Cathy McCabe, Laura Gill, Richard Byng, and Linda Gask

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G240 Prevalence and patterns of mental health-related paediatric hospital admissions, RS Bates, TV Newlove-Delgado, K Husk, and V Berry

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PROTOCOL: A comparison of the effectiveness of cognitive behavioural interventions based on delivery features for elevated symptoms of depression in adolescents, Gretchen J. Bjornstad, Shreya Sonthalia, Benjamin Rouse, Luke Timmons, Laura Whybra, and Nick Axford

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Sofosbuvir/velpatasvir for 12 weeks in hepatitis C virus-infected patients with end-stage renal disease undergoing dialysis, Sergio M. Borgia, Janet Dearden, Eric M. Yoshida, Stephen D. Shafran, Ashley Brown, Ziv Ben-Ari, Matthew E. Cramp, Curtis Cooper, Matthew Foxton, Conrado Fernandez Rodriguez, Rafael Esteban, Robert Hyland, Sophia Lu, Brian J. Kirby, Amy Meng, Svetlana Markova, Hadas Dvory-Sobol, Anu O. Osinusi, Rafael Bruck, Javier Ampuero, Stephen D. Ryder, Kosh Agarwal, Raymond Fox, David Shaw, Shariq Haider, Bernard Willems, Yoav Lurie, Jose Luis Calleja, and Edward J. Gane

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Remediating professionalism lapses in medical students and doctors: a systematic review, Nicola Brennan, Tristan Price, Julian Archer, Joe Brett, and Nicola Brennan

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Crossing boundaries: Global reorientation following transfer from the inside to the outside of an arena, Matthew G. Buckley, Luke J. Holden, Stuart G. Spicer, Alastair D. Smith, and Mark Haselgrove

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Sustainability of equality: a paradox for democracy, S Burr, YL Leung, and KS McManus

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Gender dysphoria: scientific oversight falling between responsible institutions should worry us all, Richard Byng and Susan Bewley

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From mental disorder to shared understanding: a non-categorical approach to support individuals with distress in primary care, Richard Byng, Nora Groos, and Christopher Dowrick

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Genetic Susceptibility Determines β-Cell Function and Fasting Glycemia Trajectories Throughout Childhood: A 12-Year Cohort Study (EarlyBird 76), Jerome Carayol, Joanne Hosking, Jonathan Pinkney, Julien Marquis, Aline Charpagne, Sylviane Metairon, Alison Jeffery, Jörg Hager, and Francois Pierre Martin

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Statins and Parkinson's: A complex interaction, Camille B. Carroll, Richard K.H. Wyse, and Donald G. Grosset

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Impact of Quantitative Assessment of Parkinson’s Disease-Associated Symptoms Using Wearable Technology on Treatment Decisions, Camille Carroll, Christopher Kobylecki, Monty Silverdale, and Chris Thomas

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Non-invasive coronary CT angiography-derived fractional flow reserve: A benchmark study comparing the diagnostic performance of four different computational methodologies, Jason Matthew Carson, Sanjay Pant, Carl Roobottom, Robin Alcock, Blanco P Javier, Bulant C Alberto, Yuri Vassilevski, Sergey Simakov, Timur Gamilov, Roman Pryamonosov, Fuyou Liang, Xinyang Ge, Yue Liu, and Perumal Nithiarasu

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Computational instantaneous wave‐free ratio (IFR) for patient‐specific coronary artery stenoses using 1D network models, Jason M. Carson, Carl Roobottom, Robin Alcock, and Perumal Nithiarasu

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Efficacy of three neuroprotective drugs in secondary progressive multiple sclerosis (MS-SMART): a phase 2b, multiarm, double-blind, randomised placebo-controlled trial, Jeremy Chataway, Angelis F De, Peter Connick, RA Parker, Domenico Plantone, Anisha Doshi, Nevin John, Jonathan Stutters, David MacManus, Carrasco F Prados, Frederik Barkhof, Sebastien Ourselin, Marie Braisher, Moira Ross, Gina Cranswick, Sue H. Pavitt, Gavin Giovannoni, Wheeler-Kingshott CA Gandini, Clive Hawkins, Basil Sharrack, Roger Bastow, Christopher J. Weir, Nigel Stallard, Siddharthan Chandran, Jeremy Chataway, Wheeler-Kingshott CAM Gandini, Angelis F De, Domenico Plantone, Anisha Doshi, Nevin John, Thomas Williams, Marie Braisher, Tiggy Beyene, Vanessa Bassan, Alvin Zapata, Siddharthan Chandran, Peter Connick, Dawn Lyle, James Cameron, Daisy Mollison, Shuna Colville, Baljean Dhillon, Christopher J. Weir, RA Parker, Moira Ross, Gina Cranswick, Gavin Giovannoni, Sharmilee Gnanapavan, Richard Nicholas, Waqar Rashid, Julia Aram, Helen Ford, James Overell, Carolyn Young, Heinke Arndt, Martin Duddy, Joe Guadagno, Nikolaos Evangelou, Matthew Craner, Jacqueline Palace, Jeremy Hobart, Basil Sharrack, David Paling, Clive Hawkins, Seema Kalra, B McLean, Nigel Stallard, and Roger Bastow

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11.39 Association of british neurologists sustainability special interest group (ABN sustainability SIG): formation, objectives and invitation, A Cheesman, D Blackburn, C Carroll, A Cohen, J Coebergh, D Sokhi, SH Wong, and J Woolmore