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Submissions from 2022

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Protocol: Remote care as the ‘new normal’? Multi-site case study in UK general practice, T Greenhalgh, SE Shaw, Nishio A Alvarez, A Booth, R Byng, A Clarke, F Dakin, R Davies, S Faulkner, N Hemmings, L Husain, A Kalin, E Ladds, L Moore, R Rosen, S Rybczynska-Bunt, J Wherton, and S Wieringa

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Remote care in UK general practice: baseline data on 11 case studies, T Greenhalgh, SE Shaw, Nishio A Alvarez, R Byng, A Clarke, F Dakin, S Faulkner, N Hemmings, L Husain, A Kalin, E Ladds, L Moore, R Rosen, S Rybczynska-Bunt, J Wherton, and S Wieringa

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Developing undergraduate autism education for medical students: a qualitative study, Y Dhuga, Y Feeney, L Gallaher, A White, and et al

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Loot boxes and problem gambling: Investigating the “gateway hypothesis”, Stuart Gordon Spicer, Chris Fullwood, James Close, Laura Louise Nicklin, J Lloyd, and H Lloyd

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Parkinson’s disease – palliative care needs assessment tool: adaptation and psychometric testing, Edward William Richfield, Victoria Allgar, Afaf Girgis, and Miriam J. Johnson

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Does social and economic disadvantage predict lower engagement with parenting interventions? An integrative analysis using individual participant data, Vashti Berry, G. J. Melendez-Torres, Nick Axford, Ulf Axberg, de Castro B Orobio, Frances Gardner, Maria Filomena Gaspar, BH Handegard, Judy Hutchings, A Meeting, Sinéad McGilloway, Stephen Scott, and Patty Leijten

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Social prescribing for older people and the role of the cultural sector during the COVID-19 pandemic: What are link workers' views and experiences?, Stephanie Tierney, Kamal R. Mahtani, Caroline Potter, Kathryn Eccles, Oluwafunmi Akinyemi, Jordan Gorenberg, Sebastien Libert, Geoff Wong, Amadea Turk, Kerryn Husk, Helen J. Chatterjee, Emma Webster, Beth McDougall, Harriet Warburton, and Lucy Shaw

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Durvalumab as monotherapy and in combination therapy in patients with lymphoma or chronic lymphocytic leukemia: The FUSION NHL 001 trial, C Casulo, A Santoro, G Cartron, and et al

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Socioeconomic inequality of long-term care for older people with and without dementia in England, B Hu, S Read, R Wittenberg, N Brimblecombe, and et al

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Brief intervention to reduce fatigue impact in patients with inflammatory arthritis: design and outcomes of a single-arm feasibility study, E Dures, S Bridgewater, B Abbott, J Adams, A Berry, LM McCracken, S Creanor, S Hewlett, J Lomax, M Ndosi, J Thorn, M Urban, and P Ewings

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Duration of External Neck Stabilisation (DENS) following odontoid fracture in older or frail adults: protocol for a randomised controlled trial of collar versus no collar, Julie Woodfield, Ellie Edlmann, Polly L. Black, Julia Boyd, Phillip Correia Copley, Gina Cranswick, Helen Eborall, Catriona Keerie, Sadaquate Khan, Julia Lawton, David J. Lowe, John Norrie, Angela Niven, Matthew J. Reed, Susan Deborah Shenkin, Patrick Statham, Andrew Stoddart, James Tomlinson, and Paul M. Brennan

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Interrogating intervention delivery and participants’ emotional states to improve engagement and implementation: A realist informed multiple case study evaluation of Engager, Lauren Weston, Sarah Rybczynska-Bunt, Cath Quinn, Charlotte Lennox, Mike Maguire, Mark Pearson, Alex Stirzaker, Graham Durcan, Caroline Stevenson, Jonathan Graham, Lauren Carroll, Rebecca Greer, Mark Haddad, Rachael Hunter, Rob Anderson, Roxanne Todd, Sara Goodier, Sarah Brand, Susan Michie, Tim Kirkpatrick, Sarah Leonard, Tirril Harris, William Henley, Jenny Shaw, Christabel Owens, and Richard Byng

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How can we optimise learning from trials in child and adolescent mental health?, Nick Axford, Vashti Berry, Jenny Lloyd, and Katrina Wyatt

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Influenza vaccination reduced myocardial infarctions in UK older adults: a prior event rate ratio study, AJ Streeter, LR Rodgers, F Hamilton, JAH Masoli, A Ble, WT Hamilton, and WE Henley

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Comprehensive short and long read sequencing analysis for the Gaucher and Parkinson's disease-associated GBA gene., Marco Toffoli, Xiao Chen, Fritz J. Sedlazeck, Chiao Yin Lee, Stephen Mullin, Abigail Higgins, Sofia Koletsi, Monica Emili Garcia-Segura, Esther Sammler, Sonja W. Scholz, Anthony H.V. Schapira, Michael A. Eberle, and Christos Proukakis

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Bi-allelic variants in WNT7B disrupt the development of multiple organs in humans, JDC Pereira Baptista

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Using medical education as a tool to train doctors as social innovators, Nagina Khan, Anne Rogers, Colin Melville, Rohit Shankar, Wolfgang Gilliar, Peter Byrne, Alex Serafimov, Sridevi Sira Mahalingappa, Simran Sehdev, Anna Sri, and Subodh Dave

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Deprescribing medicines in older people living with multimorbidity and polypharmacy: the TAILOR evidence synthesis, Joanne Reeve, Michelle Maden, Ruaraidh Hill, Amadea Turk, Kamal Mahtani, Geoff Wong, Dan Lasserson, Janet Krska, Dee Mangin, Richard Byng, Emma Wallace, and Ed Ranson

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Dysmorphism and immunodeficiency - one of the differential diagnoses is PAX1 related Otofaciocervical Syndrome Type 2, JDC Pereira Baptista

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Evaluating the feasibility of a real world pharmacovigilance study (OPTIMISE:MS), Ruth Dobson, Matthew Craner, Ed Waddingham, Aleisha Miller, Jayant Pindoria, Ana Cavey, Camilla Blain, Luca G De, Nikos Evangelou, Helen Ford, Paul Gallagher, Katila George, Ramos Dias R Geraldes, Paula Harman, Jeremy Hobart, Tanya King, Ruth Linighan, Niall MacDougall, Monica Marta, Stephanie Mitchell, Richard Nicholas, David Rog, Antonio Scalfari, Neil Scolding, Stewart Webb, Sarah White, Judith Wilton, Carolyn Young, and Paul M. Matthews

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Invasive coronary angiography as a tool in cardiac evaluation for liver transplant candidates, JS Nayagam, BC Norton, S Belete, J Rosinhas, K Ramos, ME Cramp, R O'Kane, WJ Cash, Z Milan, C Nicholson, K Menon, A Prachalias, P Srinivasan, G Auzinger, J Byrne, PA MacCarthy, N Melikian, K Agarwal, VR Aluvihare, D Joshi, and MA Heneghan

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Timely intervention, monitoring and education MATTERS in MS (TIME MATTERS in MS): Development of a globally applicable quality improvement tool, Jeremy Hobart, Helmut Butzkueven, Jodi Haartsen, Tjalf Ziemssen, Thirusha Lane, and Gavin Giovannoni

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Constipation in autistic people and people with learning disabilities, Rohit Shankar, Christina Maslen, Rebecca Hodge, Kim Tie, Richard Laugharne, and Kirsten Lamb

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Implications of research that excludes under-served populations, Camille Carroll

Post-COVID syndrome and adults with intellectual disability: Another vulnerable population forgotten?, Rohit Shankar, Bhathika Perera, Ashok Roy, Ken Courtenay, Richard Laugharne, and Manoj Sivan

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Double-blinded randomised placebo controlled trial of enterosgel (polymethylsiloxane polyhydrate) for the treatment of IBS with diarrhoea (IBS-D), Carol Angela Howell, Anu Kemppinen, Victoria Allgar, Matthew Dodd, Charles H. Knowles, John Mclaughlin, Preeti Pandya, Peter Whorwell, Elena Markaryan, and Yan Yiannakou

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Making implementation science more real, Mitchell N. Sarkies, Emilie Francis-Auton, Janet C. Long, Chiara Pomare, Rebecca Hardwick, and Jeffrey Braithwaite

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Hematopoietic Stem and Progenitor Cell Maintenance and Multiple Lineage Differentiation Is an Integral Function of NFATc1, de Brito C Barahona, S Klein-Hessling, Edgar Serfling, and Amiya Kumar Patra

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Patient-reported outcome measures in MS: Do development processes and patient involvement support valid quantification of clinically important variables?, Trishna Bharadia, Jo Vandercappellen, Tanuja Chitnis, Piet Eelen, Birgit Bauer, Giampaolo Brichetto, Andrew Lloyd, Hollie Schmidt, Miriam King, Jennifer Fitzgerald, Thomas Hach, and Jeremy Hobart

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The development and implementation of a computer adaptive progress test across European countries, Neil Rice, José Miguel Pêgo, Carlos Fernando Collares, Jolanta Kisielewska, and Thomas Gale

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Updated diagnostic criteria and nomenclature for neurofibromatosis type 2 and schwannomatosis: An international consensus recommendation, Scott R. Plotkin, Ludwine Messiaen, Eric Legius, Patrice Pancza, Robert A. Avery, Jaishri O. Blakeley, Dusica Babovic-Vuksanovic, Rosalie Ferner, Michael J. Fisher, Jan M. Friedman, Marco Giovannini, David H. Gutmann, Clemens Oliver Hanemann, Michel Kalamarides, Hildegard Kehrer-Sawatzki, Bruce R. Korf, Victor Felix Mautner, Mia MacCollin, Laura Papi, Katherine A. Rauen, Vincent Riccardi, Elizabeth Schorry, Miriam J. Smith, Anat Stemmer-Rachamimov, David A. Stevenson, Nicole J. Ullrich, David Viskochil, Katharina Wimmer, Kaleb Yohay, SM Huson, P Wolkenstein, DG Evans, Monique Anten, Arthur Aylsworth, Diana Baralle, Sebastien Barbarot, Fred Barker, Shay Ben-Shachar, Amanda Bergner, Didier Bessis, Ignacio Blanco, Catherine Cassiman, Patricia Ciavarelli, Maurizio Clementi, Thierry Frébourg, Alicia Gomes, Dorothy Halliday, Hanson Arvid Heiberg CH Helen, Pascal Joly, Justin T. Jordan, Matthias Karajannis, Daniela Kroshinsky, Margarita Larralde, C Lázaro, L Le, M Link, R Listernick, C Mallucci, VL Merker, C Moertel, A Mueller, J Ngeow, R Oostenbrink, R Packer, A Parry, J Peltonen, D Pichard, B Poppe, N Rezende, LO Rodrigues, T Rosser, M Ruggieri, E Serra, V Steinke-Lange, SM Stivaros, A Taylor, J Toelen, J Tonsgard, E Trevisson, M Upadhyaya, A Varan, M Wilson, H Wu, and G Zadeh

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Predictors of loneliness during the Covid-19 pandemic in people with dementia and their carers in England: findings from the DETERMIND-C19 study, R Perach, S Read, B Hicks, PR Harris, and et al

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Bone health, intellectual disability and epilepsy: An observational community‐based study, R Winterhalder, J McCabe, C Young, K Lamb, and et al

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Presentation cardiac troponin and early computed tomography coronary angiography in patients with suspected acute coronary syndrome: a pre-specified secondary analysis of the RAPID-CTCA trial, Kang Ling Wang, Carl Roobottom, Jason E. Smith, Steve Goodacre, Katherine Oatey, R O’Brien, Robert F. Storey, Nick Curzen, Liza Keating, Attila Kardos, Dirk Felmeden, Praveen Thokala, Nicholas L. Mills, David E. Newby, and Alasdair J. Gray

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Factors associated with change over time in quality of life of people with dementia: longitudinal analyses from the MODEM cohort study, Derek King, Nicolas Farina, Clare Burgon, Yvonne Feeney, Sharne Berwald, Elizabeth Bustard, Laura Gallaher, Ruth Habibi, Raphael Wittenberg, Adelina Comas-Herrera, Martin Knapp, and Sube Banerjee

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Provision of mental health care to healthcare workers during COVID-19: A call for the practice of vulnerability, J Hoare

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The effect of increasing intestinal short‐chain fatty acid concentration on gut permeability and liver injury in the context of liver disease: A systematic review, Keith Pohl, Prebashan Moodley, and Ashwin Dhanda

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Deletion of RBP-Jkappa gene in mesenchymal cells causes rickets like symptoms in the mouse, Y Gao, JV Walker, C Tredwin, and B Hu

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Tangrams: a simple visual tool for communicating the complexities of professionalism, H Neve and S Hanks

Information Asymmetry in Hospitals: Evidence of the Lack of Cost Awareness in Clinicians, J Fabes, TS Avşar, J Spiro, T Fernandez, H Eilers, S Evans, A Hessheimer, P Lorgelly, M Spiro, D Milliken, C Morkane, C Nettlefold, P Xiang, N Vogts, A Curell, A Torroella, A Melia, R Jackson, M Hanger, and A Poole

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Mental Imagery to Reduce Alcohol- related harm in patients with alcohol dependence and alcohol-related liver damaGE: the MIRAGE pilot trial protocol, Ashwin D. Dhanda, Hannah Allende, Victoria Allgar, Jackie Andrade, Matthew Peter Bailey, Lynne Callaghan, Laura Cocking, Elizabeth Goodwin, Annie Hawton, Christopher Hayward, Ben Hudson, Alison Jeffery, Angela King, Victoria Lavers, Joe Lomax, C. Anne McCune, Richard Parker, Christopher Rollinson, Jonny Wilks, and S Creanor

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“A fog that impacts everything”: a qualitative study of health-related quality of life in people living with HIV who have cognitive impairment, K Alford, S Daley, S Banerjee, and et al

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Global developments in social prescribing, DF Morse, S Sandhu, K Mulligan, S Tierney, M Polley, Giurca B Chiva, S Slade, S Dias, KR Mahtani, L Wells, H Wang, B ‍Zhao, Figueiredo CEM De, JJ Meijs, HK Nam, KH Lee, C Wallace, M Elliott, JM Mendive, D Robinson, M Palo, W Herrmann, Nielsen R Østergaard, and K Husk

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UNC45A deficiency causes microvillus inclusion disease–like phenotype by impairing myosin VB–dependent apical trafficking, Rémi Duclaux-Loras, Corinne Lebreton, Jérémy Berthelet, Fabienne Charbit-Henrion, Ophelie Nicolle, de Courtils C Revenu, Stephanie Waich, Taras Valovka, Anis Khiat, Marion Rabant, Caroline Racine, Ida Chiara Guerrera, Júlia Baptista, Maxime M. Mahe, Michael W. Hess, Béatrice Durel, Nathalie Lefort, Céline Banal, Mélanie Parisot, Cecile Talbotec, Florence Lacaille, Emmanuelle Ecochard-Dugelay, Arzu Meltem Demir, Georg F. Vogel, Laurence Faivre, Astor Rodrigues, Darren Fowler, Andreas R. Janecke, Thomas Müller, Lukas A. Huber, Fernando Rodrigues-Lima, Frank M. Ruemmele, Holm H. Uhlig, Bene F Del, Grégoire Michaux, Nadine Cerf-Bensussan, and Marianna Parlato

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Development of 'Core Outcome Sets' for Meningioma in Clinical Studies (The COSMIC Project): protocol for two systematic literature reviews, eDelphi surveys and online consensus meetings, EORTC BTG, ICOM, EANO, SNO, RANO-PRO, BNOS, SBNS, BIMS, TBTC, International Brain Tumour Alliance, Brainstrust, and Brain Tumour Foundation of Canada; Christopher P. Millward; Terri S. Armstrong; Heather Barrington; Sabrina Bell; Andrew R. Brodbelt; Helen Bulbeck; Anna Crofton; Linda Dirven; Theo Georgious; Paul L. Grundy; Abdurrahman I. Islim; Mohsen Javadpour; Sumirat M. Keshwara; Shelli D. Koszdin; Anthony G. Marson; Michael W. McDermott; Torstein R. Meling; Kathy Oliver; Puneet Plaha; Matthias Preusser; Thomas Santarius; Nisaharan Srikandarajah; Martin J.B. Taphoorn; Carole Turner; Colin Watts; Michael Weller; Paula R. Williamson; Gelareh Zadeh; Amir H. Zamanipoor Najafabadi; and Oliver Hanemann

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Present status and advances in bladder pain syndrome: central sensitisation and the urinary microbiome, I Offiah, R Campbell, A Dua, L Bombieri, and R Freeman

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Recessive PRDM13 mutations cause fatal perinatal brainstem dysfunction with cerebellar hypoplasia and disrupt Purkinje cells differentiation, Marion Coolen, Nami Altin, Karthyayani Rajamani, Eva Pereira, Karine Siquier-Pernet, Lombardi E Puig, Nadjeda Moreno, Giulia Barcia, Marianne Yvert, Annie Laquerrière, Aurore Pouliet, Patrick Nitschké, Nathalie Boddaert, Antonio Rausell, Féréchté Razavi, Alexandra Afenjar, de Villemeur T Billette, Almundher Al-Maawali, Khalid Al-Thihli, Julia Baptista, Ana Beleza-Meireles, Catherine Garel, Marine Legendre, Antoinette Gelot, Lydie Burglen, Sébastien Moutton, and Vincent Cantagrel

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Humanising health and social care support for people with intellectual and developmental disabilities: Protocol for a scoping review, Edward Meinert, Madison Milne-Ives, Rohit Shankar, Dan Goodley, Kirsten Lamb, Richard Laugharne, and Tracey Harding

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Young‐onset colorectal cancer: Insights from an English population‐based study, Joshua Franklyn, Joe Lomax, Peter L.Z. Labib, Amy Baker, Supriya Balasubramanya, Joe Natale, Muhammad Abdalkoddus, Joanne Hosking, Mark G. Coleman, and Sebastian Smolarek

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Conducting Randomized Controlled Trials of Complex Interventions in Prisons: A Sisyphean Task?, Charlotte Lennox, Sarah Leonard, Jane Senior, Caroline Hendricks, Sarah Rybczynska-Bunt, Cath Quinn, Richard Byng, and Jenny Shaw

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A cohort study of the impact of COVID‐19 on the quality of life of people newly diagnosed with dementia and their family carers, B Hicks, S Read, B Hu, S Banerjee, and et al

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Delivering Large-Scale Neurosurgical Studies in the UK: The Impact of Trainees, Aswin Chari, Rory J. Piper, Ellie Edlmann, Julie Woodfield, Paul M. Brennan, Carole Turner, Michael D. Jenkinson, Peter J. Hutchinson, Angelos G. Kolias, Daniel M. Fountain, Ruichong Ma, Ian Coulter, Aminul Ahmed, Aimun A.B. Jamjoom, Fahid T. Rasul, Claudia Craven, Michael T.C. Poon, Josephine Jung, Jignesh Tailor, Abdurrahman I. Islim, Mueez Waqar, Sara Venturini, Soham Bandyopadhyay, Robin Borchert, and Conor S. Gillespie

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Past, present and future of conservative oxygen therapy in critical care, Daniel Martin, David Harrison, Paul Mouncey, B. Ronan O'Driscoll, Mike Grocott, Lorna Miller, Doug Gould, Alvin Richards-Belle, and Kathryn Rowan

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Why do GPs rarely do video consultations? qualitative study in UK general practice, T Greenhalgh, E Ladds, G Hughes, L Moore, and et al

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A special issue of Essays in Biochemistry on current educational developments in molecular bioscience, LV Mello and HR Watson

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Clinical risk in remote consultations in general practice: findings from in-Covid-19 pandemic qualitative research, Rebecca Rosen, Sietse Wieringa, Trisha Greenhalgh, Claudia Leone, Sarah Rybczynska-Bunt, Gemma Hughes, Lucy Moore, Sara E. Shaw, Joseph Wherton, and Richard Byng

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The Development and Internal Evaluation of a Predictive Model to Identify for Whom Mindfulness-Based Cognitive Therapy Offers Superior Relapse Prevention for Recurrent Depression Versus Maintenance Antidepressant Medication, Zachary D. Cohen, Robert J. DeRubeis, Rachel Hayes, Edward R. Watkins, Glyn Lewis, Richard Byng, Sarah Byford, Catherine Crane, Willem Kuyken, Tim Dalgleish, and Susanne Schweizer

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Editorial: Nutrition and Metabolism in School-Age Children, F-P Martin, J Pinkney, and JM Saavedra

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Analysis of oxidative stress, inflammation and endothelial function following intravenous iron in chronic kidney disease in the Iron and Heart Trial, Xenophon Kassianides, Victoria Allgar, Iain C. Macdougall, Philip A. Kalra, and Sunil Bhandari

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Challenges of Incorporating Digital Health Technology Outcomes in a Clinical Trial: Experiences from PD STAT, Jacob O. Day, Stephen Smith, Alastair J. Noyce, Jane Alty, Alison Jeffery, Rebecca Chapman, and Camille Carroll

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NFAT Factors Are Dispensable for the Development but Are Critical for the Maintenance of Foxp3+ Regulatory T Cells, de Brito C Barahona and Amiya Kumar Patra

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International clinician perspectives on pandemic-associated stress in supporting people with intellectual and developmental disabilities, Rohit Shankar, Joshua Howkins, Angela Hassiotis, Elspeth Bradley, Andrew Levitas, Tanja Sappok, Amanda Sinai, and Anupam Thakur

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Enhancing Trial Delivery in Parkinson’s Disease: Qualitative Insights from PD STAT, Angie A. Kehagia, Tracie K. North, Jane Grose, Alison N. Jeffery, Laura Cocking, Rebecca Chapman, and Camille Carroll

A dominant-negative regulatory mechanism of SQSTM1 droplets-based autophagy, Shouqing Luo, Evelina Valionyte, Elizabeth R. Barrow, and Chris R. Baxter

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Linear mixed models to handle missing at random data in trial‐based economic evaluations, A Gabrio, C Plumpton, S Banerjee, and B Leurent

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Infection with the hepatitis C virus causes viral genotype-specific differences in cholesterol metabolism and hepatic steatosis, David A. Sheridan, Isaac Thom Shawa, E. Louise Thomas, Daniel J. Felmlee, Simon H. Bridge, Dermot Neely, Jeremy F. Cobbold, Elaine Holmes, Margaret F. Bassendine, and Simon D. Taylor-Robinson

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Insights into nervous system repair from the fruit fly, David Coupe and Torsten Bossing

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Opicapone in UK clinical practice: effectiveness, safety and cost analysis in patients with Parkinson's disease, Christine Schofield, K. Ray Chaudhuri, Camille Carroll, Jagdish C. Sharma, Nicola Pavese, Jonathan Evans, Thomas Foltynie, Heinz Reichmann, Laura Zurowska, Patrício Soares-Da-Silva, and Andrew Lees

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Preparedness of recent medical graduates to meet anticipated healthcare needs, T Gale, N Brennan, N Langdon, J Read, N Keates, L Burns, H Khalil, and K Mattick

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Student nurses' career preferences for working with people with dementia: A longitudinal cohort study, M Hebditch, S Daley, W Grosvenor, and et al

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X-linked Ohdo syndrome due to a novel MED12 variant detected by Rapid Exome Sequencing, Helen McDermott, Vidya Garikapati, Júlia Baptista, Harsha Gowda, and Swati Naik

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A phase II, randomized, open-label, 52-week study of seladelpar in patients with primary biliary cholangitis, Christopher L. Bowlus, Michael R. Galambos, Richard J. Aspinall, Gideon M. Hirschfield, David E.J. Jones, Yvonne Dörffel, Stuart C. Gordon, Stephen A. Harrison, Andreas E. Kremer, Marlyn J. Mayo, Paul J. Thuluvath, Cynthia Levy, Mark G. Swain, Guy W. Neff, David A. Sheridan, Carmen M. Stanca, Christoph P. Berg, Aparna Goel, Mitchell L. Shiffman, John M. Vierling, Pol Boudes, Alexandra Steinberg, Yun Jung Choi, and Charles A. McWherter

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Impact of COVID‐19 on social prescribing across an Integrated Care System: A Researcher in Residence study, Debra Westlake, Julian Elston, Alex Gude, Felix Gradinger, Kerryn Husk, and Sheena Asthana

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Minimum clinically important difference of the Social Functioning in Dementia Scale (SF-DEM): cross-sectional study and Delphi survey, T Levene, G Livingston, S Banerjee, and A Sommerlad

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Oxygen Targets During Mechanical Ventilation in the ICU: A Systematic Review and Meta-Analysis, Andrew F. Cumpstey, Alex H. Oldman, Daniel S. Martin, Andrew Smith, and Michael P.W. Grocott

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Assessing the experience of person‐centred coordinated care of people with chronic conditions in the Netherlands: Validation of the Dutch P3CEQ, Mieke Rijken, James Close, Juliane Menting, Manon Lette, Annerieke Stoop, Nick Zonneveld, Bruin S de, Helen Lloyd, and M Heymans

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Bone health, intellectual disability and epilepsy: An observational community-based study, Rohit Shankar, Robert Winterhalder, Joanne McCabe, Charlotte Young, Kirsten Lamb, Indermeet Sawhney, Caryn Jory, and Maire O'Dwyer

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‘Everyone is trying to outcompete each other’: A qualitative study of medical student attitudes to a novel peer‐assessed undergraduate teamwork module, Helen R. Watson, Mary Kate Dolley, Mohammad Perwaiz, Jocelyn Saxelby, Gianluca Bertone, Steven Burr, Tracey Collett, Robert Jeffery, and Daniel Zahra

The Role of NEDD4 E3 Ubiquitin–Protein Ligases in Parkinson’s Disease, Edgar R. Kramer, James A. Conway, and Grant Kinsman

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An 8‐year study of admissions and discharges to a specialist intellectual disability inpatient unit, J Abraham, K Purandare, J McCabe, A Wijeratne, and et al

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Effect of post-operative goal-directed fluid therapy (GDFT) on organ function after orthotopic liver transplantation: Secondary outcome analysis of the COLT randomised control trial, Farid Froghi, Vignesh Gopalan, Zachos Anastasiou, Rahul Koti, Kurinchi Gurusamy, Christine Eastgate, Margaret McNeil, Helder Filipe, Manuel Pinto, Jeshika Singh, Louise Longworth, Susan Mallett, Nick Schofield, Douglas Thorburn, Daniel Martin, and Brian R. Davidson

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Patients with moderate to severe COVID-19 have an impaired cytokine response with an exhausted and senescent immune phenotype, Ashwin D. Dhanda, Dan Felmlee, Paula Boeira, Prebashan Moodley, Huey Tan, Leticia De Paula Scalioni, Kristen Lilly, David A. Sheridan, and Matthew E. Cramp

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Therapeutic use of serious games in mental health: scoping review, A Dewhirst, R Laugharne, and R Shankar

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Dietary Nitrate Supplementation Does Not Alter Exercise Efficiency at High Altitude – Further Results From the Xtreme Alps Study, Philip J. Hennis, Andrew F. Cumpstey, Alasdair F. O’Doherty, Bernadette O. Fernandez, Edward T. Gilbert-Kawai, Kay Mitchell, Helen Moyses, Alexandra Cobb, Paula Meale, Helmut Pöhnl, Monty G. Mythen, Michael P.W. Grocott, Denny Z.H. Levett, Daniel S. Martin, and Martin Feelisch

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Bone health in adults with epilepsy and intellectual disability, Rohit Shankar and Robert Winterhalder

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Culturally adapted pulmonary rehabilitation for adults living with post-tuberculosis lung disease in Kyrgyzstan: protocol for a randomised controlled trial with blinded outcome measures, A Akylbekov, MW Orme, AV Jones, and et al

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Epilepsy Mortality: Leading Causes of Death, Co-morbidities, Cardiovascular Risk and Prevention, Rohit Shankar, Christopher M. DeGiorgio, and Brian D. Moseley

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Clinical trials in pediatric ALS: a TRICALS feasibility study, Tessa Kliest, Eijk RPA Van, Ammar Al-Chalabi, Alberto Albanese, Peter M. Andersen, Maria Del Mar Amador, Geir BrÅthen, Veronique Brunaud-Danel, Lev Brylev, William Camu, Carvalho M De, Cristina Cereda, Hakan Cetin, Delia Chaverri, Adriano Chiò, Philippe Corcia, Philippe Couratier, Marchi F De, Claude Desnuelle, Es MA Van, JesÚs Esteban, Massimiliano Filosto, Redondo A GarcÍa, Julian Grosskreutz, Clemens O. Hanemann, Trygve HolmØy, Helle HØyer, Caroline Ingre, Blaz Koritnik, Magdalena Kuzma-Kozakiewicz, Thomas Lambert, Peter N. Leigh, Christian Lunetta, Jessica Mandrioli, Christopher J. Mcdermott, Thomas Meyer, Jesus S. Mora, Susanne Petri, MÓnica Povedano, Evy Reviers, and Nilo Riva

Epilepsy in adults with neurodevelopmental disability - what every neurologist should know, Rohit Shankar, Lance V. Watkins, Christine Linehan, Christian Brandt, Francesca Snoeijen-Schouwenaars, and Paula McGowan

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Strengthening Angel Shark Conservation in the Northeastern Mediterranean Sea, I Giovos, D Katsada, RNA Spyridopoulou, D Poursanidis, and et al

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Impact of ‘Enhanced’ Intermediate Care Integrating Acute, Primary and Community Care and the Voluntary Sector in Torbay and South Devon, UK, Julian Elston, Felix Gradinger, Sheena Asthana, Matthew Fox, Louise Dawson, Dawn Butler, and Richard Byng

Seizures and emergency department: characteristics and factors of repeat adult attendees, Rohit Shankar, Sarah Lennard, William Henley, Brendan McLean, Jon Allard, Mary Parrett, Mark Jadav, and Richard Laugharne

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‘Do I have the capacity to make capacity judgements?’ Researcher reflections from a person-centred dementia support study, Sarah Griffiths, Alex Gude, Leanne Greene, Lauren Weston, Caroline L. Sutcliffe, Hannah Wheat, Tomasina M. Oh, and Richard Byng

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What factors have influenced quality of life in people with dementia and their family carers during the COVID-19 pandemic: a qualitative study, Stephanie Daley, Nazire Akarsu, Elise Armsby, Nicolas Farina, Yvonne Feeney, Bethany Fine, Laura Hughes, Joanna Pooley, Naji Tabet, Georgia Towson, and Sube Banerjee

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Loot box engagement: relationships with educational attainment, employment status and earnings in a cohort of 16,000 UK gamers, James Close, Stuart Gordon Spicer, Laura Louise Nicklin, J Lloyd, and H Lloyd

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A randomized, double-blind, placebo-controlled phase II trial to explore the effects of a GABAA-α5 NAM (basmisanil) on intellectual disability associated with Down syndrome, Celia Goeldner, Clematis Study Group, Priya S. Kishnani, Brian G. Skotko, Julian Lirio Casero, Joerg F. Hipp, Michael Derks, Maria Clemencia Hernandez, Omar Khwaja, Sian Lennon-Chrimes, Jana Noeldeke, Sabine Pellicer, Lisa Squassante, Jeannie Visootsak, Christoph Wandel, Paulo Fontoura, Xavier Liogier d’Ardhuy, Rafael De La Torre Fornell, Paul Glue, Julie Hoover-Fong, Sonja Uhlmann, Jorge Malagón Valdez, Andrew Marshall, Federico Martinón-Torres, Lorenzo Redondo-Collazo, Carmen Rodriguez-Tenreiro, Valeria Marquez Chin, Adriana G. Michel Reynoso, Ed A. Mitchell, Rebecca F. Slykerman, Sarah Loveday, Fernando Moldenhauer, Ramon Novell, Cesar Ochoa, Michael S. Rafii, Anne Sophie Rebillat, Damien Sanlaville, Pierre Sarda, Rohit Shankar, Margaret Pulsifer, Casey L. Evans, Alexandra M. Silva, Mary Ellen McDonough, Maria Stanley, Lindsay M. McCary, Stefano Vicari, William Wilcox, Giuseppe Zampino, and Alessandro Zuddas

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Changes to postdiagnostic dementia support in England and Wales during the COVID-19 pandemic: a qualitative study, A Wheatley, M Poole, and L Robinson

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COVID-19 vaccine hesitancy and anti-vaxxers – supporting healthcare workers to navigate the unvaccinated: Reflections from clinical practice, J Hoare, M Mendelson, and L Frenkel

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Therapeutic use of serious games in mental health: Scoping review, Rohit Shankar, Alice Dewhirst, and Richard Laugharne

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Adapting and validating the Autism Diagnostic Interview - Revised for use with deaf children and young people, Barry Wright, Helen Phillips, Victoria Allgar, Jennifer Sweetman, Rachel Hodkinson, Emily Hayward, Amelia Ralph-Lewis, Catarina Teige, Martin Bland, and Couteur A Le