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Submissions from 2022

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Editorial: Nutrition and Metabolism in School-Age Children, F-P Martin, J Pinkney, and JM Saavedra

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Analysis of oxidative stress, inflammation and endothelial function following intravenous iron in chronic kidney disease in the Iron and Heart Trial, Xenophon Kassianides, Victoria Allgar, Iain C. Macdougall, Philip A. Kalra, and Sunil Bhandari

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Challenges of Incorporating Digital Health Technology Outcomes in a Clinical Trial: Experiences from PD STAT, Jacob O. Day, Stephen Smith, Alastair J. Noyce, Jane Alty, Alison Jeffery, Rebecca Chapman, and Camille Carroll

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NFAT Factors Are Dispensable for the Development but Are Critical for the Maintenance of Foxp3+ Regulatory T Cells, de Brito C Barahona and Amiya Kumar Patra

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International clinician perspectives on pandemic-associated stress in supporting people with intellectual and developmental disabilities, Rohit Shankar, Joshua Howkins, Angela Hassiotis, Elspeth Bradley, Andrew Levitas, Tanja Sappok, Amanda Sinai, and Anupam Thakur

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Enhancing Trial Delivery in Parkinson’s Disease: Qualitative Insights from PD STAT, Angie A. Kehagia, Tracie K. North, Jane Grose, Alison N. Jeffery, Laura Cocking, Rebecca Chapman, and Camille Carroll

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Linear mixed models to handle missing at random data in trial‐based economic evaluations, A Gabrio, C Plumpton, S Banerjee, and B Leurent

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Infection with the hepatitis C virus causes viral genotype-specific differences in cholesterol metabolism and hepatic steatosis, David A. Sheridan, Isaac Thom Shawa, E. Louise Thomas, Daniel J. Felmlee, Simon H. Bridge, Dermot Neely, Jeremy F. Cobbold, Elaine Holmes, Margaret F. Bassendine, and Simon D. Taylor-Robinson

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Insights into nervous system repair from the fruit fly, David Coupe and Torsten Bossing

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Opicapone in UK clinical practice: effectiveness, safety and cost analysis in patients with Parkinson's disease, Christine Schofield, K. Ray Chaudhuri, Camille Carroll, Jagdish C. Sharma, Nicola Pavese, Jonathan Evans, Thomas Foltynie, Heinz Reichmann, Laura Zurowska, Patrício Soares-Da-Silva, and Andrew Lees

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Preparedness of recent medical graduates to meet anticipated healthcare needs, T Gale, N Brennan, N Langdon, J Read, N Keates, L Burns, H Khalil, and K Mattick

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Student nurses' career preferences for working with people with dementia: A longitudinal cohort study, M Hebditch, S Daley, W Grosvenor, and et al

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X-linked Ohdo syndrome due to a novel MED12 variant detected by Rapid Exome Sequencing, Helen McDermott, Vidya Garikapati, Júlia Baptista, Harsha Gowda, and Swati Naik

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A phase II, randomized, open-label, 52-week study of seladelpar in patients with primary biliary cholangitis, Christopher L. Bowlus, Michael R. Galambos, Richard J. Aspinall, Gideon M. Hirschfield, David E.J. Jones, Yvonne Dörffel, Stuart C. Gordon, Stephen A. Harrison, Andreas E. Kremer, Marlyn J. Mayo, Paul J. Thuluvath, Cynthia Levy, Mark G. Swain, Guy W. Neff, David A. Sheridan, Carmen M. Stanca, Christoph P. Berg, Aparna Goel, Mitchell L. Shiffman, John M. Vierling, Pol Boudes, Alexandra Steinberg, Yun Jung Choi, and Charles A. McWherter

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Impact of COVID‐19 on social prescribing across an Integrated Care System: A Researcher in Residence study, Debra Westlake, Julian Elston, Alex Gude, Felix Gradinger, Kerryn Husk, and Sheena Asthana

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Minimum clinically important difference of the Social Functioning in Dementia Scale (SF-DEM): cross-sectional study and Delphi survey, T Levene, G Livingston, S Banerjee, and A Sommerlad

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Oxygen Targets During Mechanical Ventilation in the ICU: A Systematic Review and Meta-Analysis, Andrew F. Cumpstey, Alex H. Oldman, Daniel S. Martin, Andrew Smith, and Michael P.W. Grocott

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Assessing the experience of person‐centred coordinated care of people with chronic conditions in the Netherlands: Validation of the Dutch P3CEQ, Mieke Rijken, James Close, Juliane Menting, Manon Lette, Annerieke Stoop, Nick Zonneveld, Bruin S de, Helen Lloyd, and M Heymans

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Bone health, intellectual disability and epilepsy: An observational community-based study, Rohit Shankar, Robert Winterhalder, Joanne McCabe, Charlotte Young, Kirsten Lamb, Indermeet Sawhney, Caryn Jory, and Maire O'Dwyer

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‘Everyone is trying to outcompete each other’: A qualitative study of medical student attitudes to a novel peer‐assessed undergraduate teamwork module, Helen R. Watson, Mary Kate Dolley, Mohammad Perwaiz, Jocelyn Saxelby, Gianluca Bertone, Steven Burr, Tracey Collett, Robert Jeffery, and Daniel Zahra

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An 8‐year study of admissions and discharges to a specialist intellectual disability inpatient unit, J Abraham, K Purandare, J McCabe, A Wijeratne, and et al

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Effect of post-operative goal-directed fluid therapy (GDFT) on organ function after orthotopic liver transplantation: Secondary outcome analysis of the COLT randomised control trial, Farid Froghi, Vignesh Gopalan, Zachos Anastasiou, Rahul Koti, Kurinchi Gurusamy, Christine Eastgate, Margaret McNeil, Helder Filipe, Manuel Pinto, Jeshika Singh, Louise Longworth, Susan Mallett, Nick Schofield, Douglas Thorburn, Daniel Martin, and Brian R. Davidson

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Patients with moderate to severe COVID-19 have an impaired cytokine response with an exhausted and senescent immune phenotype, Ashwin D. Dhanda, Dan Felmlee, Paula Boeira, Prebashan Moodley, Huey Tan, Leticia De Paula Scalioni, Kristen Lilly, David A. Sheridan, and Matthew E. Cramp

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Therapeutic use of serious games in mental health: scoping review, A Dewhirst, R Laugharne, and R Shankar

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Dietary Nitrate Supplementation Does Not Alter Exercise Efficiency at High Altitude – Further Results From the Xtreme Alps Study, Philip J. Hennis, Andrew F. Cumpstey, Alasdair F. O’Doherty, Bernadette O. Fernandez, Edward T. Gilbert-Kawai, Kay Mitchell, Helen Moyses, Alexandra Cobb, Paula Meale, Helmut Pöhnl, Monty G. Mythen, Michael P.W. Grocott, Denny Z.H. Levett, Daniel S. Martin, and Martin Feelisch

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Bone health in adults with epilepsy and intellectual disability, Rohit Shankar and Robert Winterhalder

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Culturally adapted pulmonary rehabilitation for adults living with post-tuberculosis lung disease in Kyrgyzstan: protocol for a randomised controlled trial with blinded outcome measures, A Akylbekov, MW Orme, AV Jones, and et al

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Epilepsy Mortality: Leading Causes of Death, Co-morbidities, Cardiovascular Risk and Prevention, Rohit Shankar, Christopher M. DeGiorgio, and Brian D. Moseley

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Clinical trials in pediatric ALS: a TRICALS feasibility study, Tessa Kliest, Eijk RPA Van, Ammar Al-Chalabi, Alberto Albanese, Peter M. Andersen, Maria Del Mar Amador, Geir BrÅthen, Veronique Brunaud-Danel, Lev Brylev, William Camu, Carvalho M De, Cristina Cereda, Hakan Cetin, Delia Chaverri, Adriano Chiò, Philippe Corcia, Philippe Couratier, Marchi F De, Claude Desnuelle, Es MA Van, JesÚs Esteban, Massimiliano Filosto, Redondo A GarcÍa, Julian Grosskreutz, Clemens O. Hanemann, Trygve HolmØy, Helle HØyer, Caroline Ingre, Blaz Koritnik, Magdalena Kuzma-Kozakiewicz, Thomas Lambert, Peter N. Leigh, Christian Lunetta, Jessica Mandrioli, Christopher J. Mcdermott, Thomas Meyer, Jesus S. Mora, Susanne Petri, MÓnica Povedano, Evy Reviers, and Nilo Riva

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Strengthening Angel Shark Conservation in the Northeastern Mediterranean Sea, I Giovos, D Katsada, RNA Spyridopoulou, D Poursanidis, and et al

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Impact of ‘Enhanced’ Intermediate Care Integrating Acute, Primary and Community Care and the Voluntary Sector in Torbay and South Devon, UK, Julian Elston, Felix Gradinger, Sheena Asthana, Matthew Fox, Louise Dawson, Dawn Butler, and Richard Byng

Seizures and emergency department: characteristics and factors of repeat adult attendees, Rohit Shankar, Sarah Lennard, William Henley, Brendan McLean, Jon Allard, Mary Parrett, Mark Jadav, and Richard Laugharne

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‘Do I have the capacity to make capacity judgements?’ Researcher reflections from a person-centred dementia support study, Sarah Griffiths, Alex Gude, Leanne Greene, Lauren Weston, Caroline L. Sutcliffe, Hannah Wheat, Tomasina M. Oh, and Richard Byng

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What factors have influenced quality of life in people with dementia and their family carers during the COVID-19 pandemic: a qualitative study, Stephanie Daley, Nazire Akarsu, Elise Armsby, Nicolas Farina, Yvonne Feeney, Bethany Fine, Laura Hughes, Joanna Pooley, Naji Tabet, Georgia Towson, and Sube Banerjee

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Loot box engagement: relationships with educational attainment, employment status and earnings in a cohort of 16,000 UK gamers, James Close, Stuart Gordon Spicer, Laura Louise Nicklin, J Lloyd, and H Lloyd

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A randomized, double-blind, placebo-controlled phase II trial to explore the effects of a GABAA-α5 NAM (basmisanil) on intellectual disability associated with Down syndrome, Celia Goeldner, Clematis Study Group, Priya S. Kishnani, Brian G. Skotko, Julian Lirio Casero, Joerg F. Hipp, Michael Derks, Maria Clemencia Hernandez, Omar Khwaja, Sian Lennon-Chrimes, Jana Noeldeke, Sabine Pellicer, Lisa Squassante, Jeannie Visootsak, Christoph Wandel, Paulo Fontoura, Xavier Liogier d’Ardhuy, Rafael De La Torre Fornell, Paul Glue, Julie Hoover-Fong, Sonja Uhlmann, Jorge Malagón Valdez, Andrew Marshall, Federico Martinón-Torres, Lorenzo Redondo-Collazo, Carmen Rodriguez-Tenreiro, Valeria Marquez Chin, Adriana G. Michel Reynoso, Ed A. Mitchell, Rebecca F. Slykerman, Sarah Loveday, Fernando Moldenhauer, Ramon Novell, Cesar Ochoa, Michael S. Rafii, Anne Sophie Rebillat, Damien Sanlaville, Pierre Sarda, Rohit Shankar, Margaret Pulsifer, Casey L. Evans, Alexandra M. Silva, Mary Ellen McDonough, Maria Stanley, Lindsay M. McCary, Stefano Vicari, William Wilcox, Giuseppe Zampino, and Alessandro Zuddas

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Changes to postdiagnostic dementia support in England and Wales during the COVID-19 pandemic: a qualitative study, A Wheatley, M Poole, and L Robinson

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COVID-19 vaccine hesitancy and anti-vaxxers – supporting healthcare workers to navigate the unvaccinated: Reflections from clinical practice, J Hoare, M Mendelson, and L Frenkel

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Therapeutic use of serious games in mental health: Scoping review, Rohit Shankar, Alice Dewhirst, and Richard Laugharne

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Adapting and validating the Autism Diagnostic Interview - Revised for use with deaf children and young people, Barry Wright, Helen Phillips, Victoria Allgar, Jennifer Sweetman, Rachel Hodkinson, Emily Hayward, Amelia Ralph-Lewis, Catarina Teige, Martin Bland, and Couteur A Le

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Adapting and validating the Autism Diagnostic Observation Schedule Version 2 for use with deaf children and young people, Helen Phillips, Barry Wright, Victoria Allgar, Helen McConachie, Jennifer Sweetman, Rebecca Hargate, Rachel Hodkinson, Martin Bland, Hannah George, Anna Hughes, Emily Hayward, Las Heras VFG De, and Couteur A Le

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Emotions, psychological safety and recommendations for designing remediation programmes, Nicola Brennan

Positive Behavioural Support in the UK: A State of the Nation Report, Rohit Shankar

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Theory protection: do humans protect existing associative links?, Stuart G. Spicer, Chris J. Mitchell, Andy J. Wills, Katie L. Blake, and Peter M. Jones

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Challenges and opportunities in the care of chronic subdural haematoma: perspectives from a multi-disciplinary working group on the need for change, DJ Stubbs, B Davies, P Hutchinson, DK Menon, TH Bashford, E Edlmann, A Bateman, P Braude, R Burnstein, S Camp, G Carr, PJ Clarkson, J Coles, J Dhesi, J Dinsmore, M Dixon-Woods, A Ercole, N Evans, A Figaji, S Griffin, P Grundy, P Hartley, A Joannides, A Kolias, F Lecky, P May, I Moppett, S Morris, M Nathanson, J Outtrim, N Owen, N Phillips, T Quinn, S Ralhan, D Sapsford, DJH Shipway, C Skitterall, M Smith, M Swart, W Thomas, K Walton, N Wareham, P Whitfield, SR Wilson, and M Vindlacheruvu

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Developmental impact of glutamate transporter overexpression on dopaminergic neuron activity and stereotypic behavior, M Cohan, Jared M. Kopelman, Hannah Yueh, Hannah Yueh, Natasha Greene, Alexander Z. Harris, Peter D. Balsam, E. David Leonardo, Edgar R. Kramer, Jeremy Veenstra-VanderWeele, and Susanne E. Ahmari

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Covid-19 and the quality of life of people with dementia and their carers—The TFD-C19 study, Stephanie Daley, Nicolas Farina, Laura Hughes, Elise Armsby, Nazire Akarsu, Joanna Pooley, Georgia Towson, Yvonne Feeney, Naji Tabet, Bethany Fine, and Sube Banerjee

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Gambling and Gaming in the United Kingdom during the COVID-19 Lockdown, James Close, Stuart Gordon Spicer, Laura Louise Nicklin, J Lloyd, Ben Whalley, and H Lloyd

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Hypothesis: Disrupted Regulation of the Intracranial Vascular and Cerebrospinal Fluid Circulations Causes Nocturia, Holly A. Roy, Matthew D. Smith, Hollie Blaber, Christopher H. Fry, Erlick A. Pereira, and Marcus J. Drake

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Efficacy and safety of VNS therapy or continued medication management for treatment of adults with drug-resistant epilepsy: systematic review and meta-analysis, Sarah Batson, Rohit Shankar, Joan Conry, Jane Boggs, Rodney Radtke, Stephen Mitchell, Francesca Barion, Joanna Murphy, and Vanessa Danielson

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Tangrams: a simple visual tool for communicating the complexities of professionalism, H Neve and S Hanks

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The self-management abilities test (SMAT): a tool to identify the self-management abilities of adults with bronchiectasis, KR Smalley, L Aufegger, K Flott, EK Mayer, and A Darzi

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Factors Associated With Relapse and Treatment of Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease in the United Kingdom, Chanjira Satukijchai, Romina Mariano, Silvia Messina, Mario Sa, Mark R. Woodhall, Neil P. Robertson, Lim Ming, Evangeline Wassmer, Rachel Kneen, Saif Huda, Anu Jacob, Camilla Blain, Christopher Halfpenny, Cheryl Hemingway, Eoin O'Sullivan, Jeremy Hobart, Leonora K. Fisniku, Roswell Martin, Ruth Dopson, Sarah A. Cooper, Victoria Williams, Patrick J. Waters, Sithara Ramdas, MI Leite, and Jacqueline Palace

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Receipt of help by people with cognitive impairment: results from the English Longitudinal Study of Ageing, S Read, B Hu, J Dixon, N Brimblecombe, and et al

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COVID-19 pandemic impact on psychotropic prescribing for adults with intellectual disability: An observational study in English specialist community services, Rohit Shankar, Danial Naqvi, Bhathika Perera, Sarah Mitchell, and Rory Sheehan

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Efficacy and Safety of VNS Therapy or Continued Medication Management for Treatment of Adults with Drug-Resistant Epilepsy: Systematic Review and Meta-Analysis: Preprint, Sarah Batson, Rohit Shankar, Joan Conry, Jane Boggs, Rodney Radtke, Stephen Mitchell, Francesca Barion, Joanna Murphy, and Vanessa Danielson

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A review of the pharmacotherapeutic considerations for managing epilepsy in people with autism, Rohit Shankar, Lance V. Watkins, and Maire O’Dwyer

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Correction to: Epilepsy related multimorbidity, polypharmacy and risks in adults with intellectual disabilities: a national study, Rohit Shankar, James J. Sun, Bhathika Perera, William Henley, Heather Angus-Leppan, Indermeet Sawhney, Lance Watkins, Kiran N. Purandare, Mogbeyiteren Eyeoyibo, Mark Scheepers, Geraldine Lines, Robert Winterhalder, Samantha Ashby, Silva R De, Jonjo Miller, David E. Philpott, Chris Ashwin, Joshua Howkins, Harriet Slater, and David Medhurst

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COVID-19 pandemic impact on psychotropic prescribing for adults with intellectual disability: an observational study in English specialist community services, D Naqvi, B Perera, S Mitchell, R Sheehan, and R Shankar

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Description of the cross‐cultural process adopted in the STRiDE (STrengthening Responses to dementia in DEveloping countries) program: A methodological overview, Nicolas Farina, Roxanne Jacobs, Tara Puspitarini Sani, Marguerite Schneider, Imelda Theresia, Yuda Turana, Fasihah Irfani Fitri, Emiliano Albanese, K Lorenz‐Dant, Sumaiyah Docrat, PD Toit, Cleusa P. Ferri, Ishtar Govia, A Comas‐Herrera, Aliaa Ibnidris, Martin Knapp, and Sube Banerjee

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Efficacy of prolonged-release fampridine versus placebo on walking ability, dynamic and static balance, physical impact of multiple sclerosis, and quality of life: an integrated analysis of MOBILE and ENHANCE, Raymond Hupperts, Claudio Gasperini, Jan Lycke, Tjalf Ziemssen, Peter Feys, Shan Xiao, Carlos Acosta, Thijs Koster, and Jeremy Hobart

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Engaging Stakeholders in Realist Programme Theory Building: Insights from the Prospective Phase of a Primary Care Dementia Support Study, Sarah Griffiths, Lauren Weston, Sarah Morgan-Trimmer, Hannah Wheat, Alex Gude, Lorna Manger, Tomasina M. Oh, Paul Clarkson, Cath Quinn, Rod Sheaff, Mike Clark, Ian Sherriff, and Richard Byng

Epilepsy related multimorbidity, polypharmacy and risks in adults with intellectual disabilities: a national study, Rohit Shankar, James J. Sun, Bhathika Perera, William Henley, Heather Angus-Leppan, Indermeet Sawhney, Lance Watkins, Kiran N. Purandare, Mogbeyiteren Eyeoyibo, Mark Scheepers, Geraldine Lines, Robert Winterhalder, Samantha Ashby, Silva R De, Jonjo Miller, David E. Philpott, Chris Ashwin, Joshua Howkins, Harriet Slater, and David Medhurst

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Human Endogenous Retrovirus Type K promotes proliferation of Merlin-negative schwannoma and meningioma which can be inhibited by anti-retroviral and anti-TEAD drugs, CO Hanemann, E Maze, B Agit, S Reeves, D Hilton, DB Parkinson, L Laraba, E Ercolano, K Kurian, R Belshaw, and S Ammoun

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Intraductal fully covered self-expanding metal stents in the management of post-liver transplant anastomotic strictures: a UK wide experience, Wafaa Ahmed, Dave Kyle, Amardeep Khanna, John Devlin, David Reffitt, Zeino Zeino, George Webster, Simon Phillpotts, Robert Gordon, Gareth Corbett, William Gelson, Manu Nayar, Haider Khan, Matthew Cramp, Jonathan Potts, Waleed Fateen, Hamish Miller, Bharat Paranandi, Matthew Huggett, Simon M. Everett, Vinod S. Hegade, Rebecca O’Kane, Ryan Scott, Neil McDougall, Phillip Harrison, and Deepak Joshi

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POSC289 Cost-Effectiveness of Vagus Nerve Stimulation with Anti-Seizure Medication Versus Anti-Seizure Medication Alone in the Management of Drug Resistant Epilepsy in England, C Raspin, Rohit Shankar, Francesca Barion, V Pollit, Joanna Murphy, L Sawyer, and Vanessa Danielson

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Predictors and determinants of albuminuria in people with prediabetes and diabetes based on smoking status: A cross-sectional study using the UK Biobank data, Debasish Kar, Aya El-Wazir, Gayathri Delanerolle, Anna Forbes, James P. Sheppard, Mintu Nath, Mark Joy, Nicholas Cole, J. Ranjit Arnold, Andrew Lee, Michael Feher, Melanie J. Davies, Kamlesh Khunti, Simon de Lusignan, and Elizabeth Goyder

Rapid development of a ventilator for use during the COVID-19 pandemic: Clinical, human factor & engineering considerations, M Wittenberg, J Fabes, D Strange, M Griffin, D Lock, and M Spiro

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Real Talk: A Realist Dialogic Approach in a Realist Evaluation, Emilie Francis-Auton, Mitchell N. Sarkies, Chiara Pomare, Janet C. Long, Rebecca Hardwick, Hoa Mi Nguyen, and Jeffrey Braithwaite

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Self-management intervention to reduce pulmonary exacerbations by supporting treatment adherence in adults with cystic fibrosis: a randomised controlled trial, Martin J. Wildman, CFHealthHub Study Team, Alicia O’Cathain, Chin Maguire, Madelynne A. Arden, Marlene Hutchings, Judy Bradley, Stephen J. Walters, Pauline Whelan, John Ainsworth, Iain Buchan, Laura Mandefield, Laura Sutton, Paul Tappenden, Rachel A. Elliott, Zhe Hui Hoo, Sarah J. Drabble, Daniel Beever, H. Cantrill, J. Nicholl, S. Michie, S. Waterhouse, L. Robinson, A. Scott, S. Antrobus, E. Lumley, A. N. Biz, D. Hind, C. Orchard, and E. Nash

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“What works” registries of interventions to improve child and youth psychosocial outcomes: A critical appraisal, Nick Axford, Louise Morpeth, Gretchen Bjornstad, Tim Hobbs, and Vashti Berry

Submissions from 2021

Perceptions about mental healthcare for people with epilepsy in Africa, Rohit Shankar, Chloe Gilkinson, Michael Kinney, Tolu Olaniyan, Bankole Murtala, Margaret Sipilon, Andrew Malunga, and Sohna M. Joof

An 8-year study of admissions and discharges to a specialist intellectual disability inpatient unit, Rohit Shankar, Julie Abraham, Kiran Purandare, Joanne McCabe, Anusha Wijeratne, Evelina Eggleston, Katy Oak, Richard Laugharne, and Ashok Roy

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Key components of post-diagnostic support for people with dementia and their carers: A qualitative study, C Bamford, A Wheatley, G Brunskill, L Booi, and et al

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P-P06 Ward based goal directed fluid therapy (GDFT) in acute pancreatitis (GAP) trial: a feasibility randomised controlled trial [ISRCTN 36077283], F Froghi, F Soggiu, F Ricciardi, C Vindrola-Padros, L Floros, D Martin, H Filipe, M Varcada, K Gurusamy, S Bhattacharya, A Fanshawe, B Dolcea, P Mathur, and B Davidson

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Ward based goal directed fluid therapy (GDFT) in acute pancreatitis (GAP) trial: a feasibility randomised controlled trial [ISRCTN 36077283], F Froghi, F Soggiu, F Ricciardi, C Vindrola-Padros, L Floros, D Martin, H Filipe, M Varcada, K Gurusamy, S Bhattacharya, A Fanshawe, B Dolcea, P Mathur, and B Davidson

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A report from the NIHR UK working group on remote trial delivery for the COVID-19 pandemic and beyond, Jane A.H. Masoli, Kim Down, Gary Nestor, Sharon Hudson, John T. O’Brien, James D. Williamson, Carolyn A. Young, and Camille Carroll

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Is activation of GDNF/RET signaling the answer for successful treatment of Parkinson's disease? A discussion of data from the culture dish to the clinic, Edgar R. Kramer and James A. Conway

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The Current Provision of Mental Health Services for Individuals with Mild Intellectual Disability: A Scoping Review, Rohit Shankar, Catherine Walton, David Medhurst, and Giri Madhavan

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Drivers of international migration of doctors to and from the United Kingdom, N Brennan, N Langdon, M Bryce, T Gale, A Knapton, L Burns, and N Humphries

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The caspase-6–p62 axis modulates p62 droplets based autophagy in a dominant-negative manner, Evelina Valionyte, Yi Yang, Sophie A. Griffiths, Amelia T. Bone, Elizabeth R. Barrow, Vikram Sharma, Boxun Lu, and Shouqing Luo

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Protocol for a prospective double-blind, randomised, placebo-controlled feasibility trial of octreotide infusion during liver transplantation, Jeremy Fabes, Gareth Ambler, Bina Shah, Norman R. Williams, Daniel Martin, Brian R. Davidson, and Michael Spiro

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A multicentre prospective double blinded randomised controlled trial of intravenous iron (ferric Derisomaltose (FDI)) in Iron deficient but not anaemic patients with chronic kidney disease on functional status, S. Bhandari, V. Allgar, A. Lamplugh, I. Macdougall, and P. A. Kalra

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Developmental Impact of Glutamate Transporter Overexpression on Dopaminergic Neuron Activity and Stereotypic Behavior, M Chohan, J Kopelman, H Yueh, Z Fazlali, N Greene, A Harris, P Balsam, ED Leonardo, E Kramer, J Veenstra-Vanderweele, and S Ahmari

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Human endogenous retrovirus type K promotes proliferation and confers sensitivity to anti-retroviral drugs in Merlin-negative schwannoma and meningioma., Emmanuel A. Maze, Bora Agit, Shona Reeves, David A. Hilton, David B. Parkinson, Liyam Laraba, Emanuela Ercolano, Kathreena M. Kurian, C. Oliver Hanemann, Robert D. Belshaw, and Sylwia Ammoun

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The remote assessment of parkinsonism supporting the ongoing development of interventions in Gaucher disease, Abigail Louise Higgins, Marco Toffoli, Stephen Mullin, Chiao Yin Lee, Sofia Koletsi, Micol Avenali, Fabio Blandini, and Anthony H.V. Schapira

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OPTIMISE: MS study protocol: a pragmatic, prospective observational study to address the need for, and challenges with, real world pharmacovigilance in multiple sclerosis, Ruth Dobson, Matthew Craner, Ed Waddingham, Aleisha Miller, Ana Cavey, Stewart Webb, Cheryl Hemingway, Jeremy Hobart, Nikos Evangelou, Neil Scolding, David Rog, Richard Nicholas, Monica Marta, Camilla Blain, Carolyn Anne Young, Helen L. Ford, and Paul M. Matthews

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Mental Health Provision in UK Secondary Schools, Megan Garside, Barry Wright, Roshanak Nekooi, and Victoria Allgar

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Health and wellbeing outcomes and social prescribing pathways in community‐based support for autistic adults: A systematic mapping review of reviews, Charlotte Featherstone, Richard A. Sharpe, Nick Axford, Sheena Asthana, and Kerryn Husk

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Health and wellbeing outcomes and social prescribing pathways in community‐based support for autistic adults: A systematic mapping review of reviews, C Featherstone, RA Sharpe, N Axford, S Asthana, and K Husk

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Attention-deficit hyperactivity disorder in people with intellectual disability: Statistical approach to developing a bespoke screening tool, Rohit Shankar, Indermeet Sawhney, Bhathika Perera, Paul Bassett, Asif Zia, and Regi T. Alexander

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A digital self-management program (help to overcome problems effectively) for people living with cancer: Feasibility randomized controlled trial, H Wright, F Martin, W Clyne, CCT Clark, and et al

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A feasibility randomised controlled trial of targeted oxygen therapy in mechanically ventilated critically ill patients, Daniel S. Martin, Margaret McNeil, Chris Brew-Graves, Helder Filipe, Ronan O’Driscoll, Jia Liu Stevens, Rachel Burnish, Andrew F. Cumpstey, Norman R. Williams, Michael G. Mythen, and Michael P.W. Grocott

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Attention-deficit hyperactivity disorder in people with intellectual disability: statistical approach to developing a bespoke screening tool, I Sawhney, B Perera, P Bassett, and et al

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Letter to the Editor. A UK perspective on gender diversity in American neurosurgery training programs, Ellie Edlmann, Phillip Copley, Mark Hughes, and Julie Woodfield

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People with epilepsy and intellectual disability: More than a sum of two conditions, FM Snoeijen-Schouwenaars, C Young, C Rowe, and et al

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Mapping of population disparities in the cholangiocarcinoma urinary metabolome, Munirah Alsaleh, Zoe Leftley, Thomas O’Connor, Thomas Hughes, Thomas A. Barbera, Larry K. Koomson, Abigail Zabron, Helen Reeves, Matthew Cramp, Stephen D. Ryder, Shaun Greer, Martin Prince, Paiboon Sithithaworn, Narong Khuntikeo, Watcharin Loilome, Puangrat Yongvanit, I. Jane Cox, Roger Williams, Christopher A. Wadsworth, Elaine Holmes, Kathryn Nash, Ross Andrews, and Simon D. Taylor-Robinson

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Study of mirtazapine for agitated behaviours in dementia (SYMBAD): a randomised, double-blind, placebo-controlled trial, Sube Banerjee, Juliet High, Susan Stirling, Lee Shepstone, Ann Marie Swart, Tanya Telling, Catherine Henderson, Clive Ballard, Peter Bentham, Alistair Burns, Nicolas Farina, Chris Fox, Paul Francis, Robert Howard, Martin Knapp, Iracema Leroi, Gill Livingston, Ramin Nilforooshan, Shirley Nurock, John O'Brien, Annabel Price, Alan J. Thomas, and Naji Tabet

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The Effect of Pre-operative Exercise Intervention on Patient Outcomes Following Bariatric Surgery: a Systematic Review and Meta-analysis, Belinda J. Durey, Dominic Fritche, Daniel S. Martin, and Lawrence M.J. Best

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The impact of smoking cessation on multiple sclerosis disease progression, Jeff Rodgers, Tim Friede, Frederick W. Vonberg, Cris S. Constantinescu, Alasdair Coles, Jeremy Chataway, Martin Duddy, Hedley Emsley, H Ford, Leonora Fisniku, Ian Galea, Timothy Harrower, Jeremy Hobart, Huseyin Huseyin, Christopher M. Kipps, Monica Marta, Gavin V. Mcdonnell, Brendan Mclean, Owen R. Pearson, David Rog, Klaus Schmierer, Basil Sharrack, Agne Straukiene, Heather C. Wilson, DV Ford, Rod M. Middleton, and Richard Nicholas