Browse research from the Peninsula Medical School.

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Submissions from 2023

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The potential unintended consequences of Mental Health Act reforms in England and Wales on people with intellectual disability and/or autism, Rohit Shankar, Samuel Tromans, Kamaldeep Bhui, Indermeet Sawhney, Mahesh Odiyoor, Ken Courtenay, Ashok Roy, Harm Boer, Regi Alexander, Asit Biswas, Jane Mccarthy, Gautam Gulati, and Richard Laugharne

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Cross-cultural adaptation of the EAST and CASE screening tools for elder abuse in South Africa, Roxanne Jacobs, Nicolas Farina, Marguerite Schneider, and on behalf of the STRiDE programme

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Overexpression of Both Human Sodium Iodide Symporter (NIS) and BRG1-Bromodomain Synergistically Enhances Radioiodine Sensitivity by Stabilizing p53 through NPM1 Expression, J Na, C-H Lee, J-K Chung, and H Youn

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Routinely used interventions to improve attachment in infants and young children: a national survey and two systematic reviews, Barry Wright, Pasco Fearon, Megan Garside, Eleni Tsappis, Elaine Amoah, Danya Glaser, Victoria Allgar, Helen Minnis, Matthew Woolgar, Rachel Churchill, Dean McMillan, Peter Fonagy, Alison O’Sullivan, and Michelle McHale

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Understanding and Improving Older People’s Well-Being through Social Prescribing Involving the Cultural Sector: Interviews from a Realist Evaluation, Jordan Gorenberg, Stephanie Tierney, Geoff Wong, Amadea Turk, Sebastien Libert, Caroline Potter, Kathryn Eccles, Shona Forster, Kerryn Husk, Helen J. Chatterjee, Emma Webster, Beth McDougall, Harriet Warburton, Lucy Shaw, and Kamal R. Mahtani

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Using digital technologies to facilitate social inclusion during the COVID‐19 pandemic: Experiences of co‐resident and non‐co‐resident family carers of people with dementia from DETERMIND‐C19, B Hicks and DETERMIND team

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Comparison of Diagnostic Profiles of Deaf and Hearing Children with a Diagnosis of Autism, Rachel Hodkinson, Helen Phillips, Victoria Allgar, Alys Young, Couteur A Le, Andrew Holwell, Catarina Teige, and Barry Wright

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Graduates’ preparedness for the changing doctor‐patient relationship: a qualitative study, Nicola Brennan, Nicola Langdon, Natasha Keates, Karen Mattick, and Thomas Gale

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How Well Prepared Are Dental Students and New Graduates in Pakistan—A Cross-Sectional National Study, Muhammad Qasim Javed, Shazia Nawabi, Usman Anwer Bhatti, Sundus Atique, Mustafa Hussein AlAttas, Ayman M. Abulhamael, Daniel Zahra, and Kamran Ali

Hyphenating paper-based biosensors with smartphones, Michael J. Dillon and Katrina Campbell

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CSF rhinorrhoea after endonasal intervention to the skull base (CRANIAL): A multicentre prospective observational study, E Edlmann

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Equality pledges: A novel approach to embedding EDI and promoting positive culture change in a UK university, HR Watson, H Wisdom, C Michael, N Marshall, and H Neve

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An evidence-based approach to provide essential and desirable components to develop surveys on Sudden Unexpected Death in Epilepsy (SUDEP) for doctors: A focused review, R. Shankar, L. V. Watkins, S. Ashby, J. Hanna, W. Henley, and R. Laugharne

Awareness of social care needs in people with epilepsy and intellectual disability, R. Shankar, A. Gabrielsson, S. Tromans, H. Newman, P. Triantafyllopoulou, A. Hassiotis, P. Bassett, L. Watkins, I. Sawhney, M. Cooper, L. Griffiths, A. Pullen, A. Roy, H. Angus-Leppan, RH Thomas, M. Kinney, and P. Tittensor

Cardiovascular risk factors in secondary progressive multiple sclerosis: A cross‐sectional analysis from the MS‐STAT2 randomized controlled trial, Thomas Williams, Nevin John, Alberto Calvi, Alessia Bianchi, Floriana De Angelis, Anisha Doshi, Sarah Wright, Madiha Shatila, Marios C. Yiannakas, Fatima Chowdhury, Jon Stutters, Antonio Ricciardi, Ferran Prados, David MacManus, Marie Braisher, James Blackstone, Olga Ciccarelli, CAM Gandini Wheeler‐Kingshott, Frederik Barkhof, Jeremy Chataway, and Jeremy Hobart

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COVID-19 vaccine effectiveness against hospitalisation and death of people in clinical risk groups during the Delta variant period: English primary care network cohort study, Heather J. Whitaker, Ruby S.M. Tsang, Rachel Byford, Carole Aspden, Elizabeth Button, Praveen Sebastian Pillai, Gavin Jamie, Debasish Kar, John Williams, Mary Sinnathamby, Gemma Marsden, William H. Elson, Meredith Leston, Sneha Anand, Cecilia Okusi, Xuejuan Fan, Ezra Linley, Cathy Rowe, Silvia DArcangelo, Ashley D. Otter, Joanna Ellis, F.D. Richard Hobbs, Victoria Tzortziou-Brown, Maria Zambon, Mary Ramsay, Kevin E. Brown, Gayatri Amirthalingam, Nick J. Andrews, Simon de Lusignan, and Jamie Lopez Bernal

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Engaging youth at risk of violence in services: messages from research, Nick Axford, John Tredinnick-Rowe, S Rybczynska-Bunt, Lorna Burns, Finlay Green, and Tom Thompson

Fast-track extubation after orthotopic liver transplant associates with reduced incidence of acute kidney injury and renal replacement therapy: A propensity-matched analysis, J Fabes, G Wells, Z Abdi, R Bhatia, P Muehlschlegel, M Fortune-Ely, D Krzanicki, S Rahman, and M Spiro

Geographical variations in long term colorectal cancer outcomes in England: a contemporary population analysis revealing the north–south divide in colorectal cancer survival, Joshua Franklyn, Joe Lomax, Amy Baker, Muhammad Abdalkoddus, Joanne Hosking, Mark G. Coleman, and Sebastian Smolarek

Goal-Directed Haemodynamic Therapy Improves Patient Outcomes in Kidney Transplantation, J Fabes, Midani A Al, AS Sarna, DH Hadi, SA Naji, NR Banga, GL Jones, PD Berry, and MD Wittenberg

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Longitudinal realist evaluation of the Dementia PersonAlised Care Team (D-PACT) intervention: protocol, Hannah Wheat, Lauren Weston, Tomasina M. Oh, Sarah Morgan-Trimmer, Wendy Ingram, Sarah Griffiths, Rod Sheaff, Paul Clarkson, Antonieta Medina-Lara, Crispin Musicha, Stuart Spicer, Obioha Ukoumunne, Victoria Allgar, Siobhan Creanor, Michael Clark, Cath Quinn, Alex Gude, Rose McCabe, Saqba Batool, Lorna Smith, Debra Richards, Hannah Shafi, Bethany Warwick, Reena Lasrado, Basharat Hussain, Hannah Jones, Sonia Dalkin, Angela Bate, Ian Sherriff, Louise Robinson, and Richard Byng

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Modern cemented Furlong hemiarthroplasty: Are dislocations rates better?, C. U. Menakaya, M. Shah, H. Ingoe, R. Malhotra, A. Mannan, T. Boddice, V. Allgar, S. Gopal, A. Mohsen, and N. Muthukumar

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Oral microbes and the formation of cerebral abscesses: A single-centre retrospective study, Raul Bescos, Holly Roy, Ewen McColl, Umar Rehman, Elizabeth Cray, Louise A. Belfield, King David Nweze, Kevin Tsang, William Singleton, Peter Whitfield, and Zoe Brookes

Poo Matters! A scoping review of impact of constipation on epilepsy, Rohit Shankar, Alexandra Gabrielsson, Samuel Tromans, Lance Watkins, Lisa Burrows, and Richard Laugharne

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Post-COVID syndrome and adults with intellectual disability: another vulnerable population forgotten?, R Shankar, B Perera, A Roy, and et al

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Presentation, management, and outcomes of cauda equina syndrome up to one year after surgery, using clinician and participant reporting: a multi-centre prospective cohort study, Julie Woodfield, Ingrid Hoeritzauer, Aimun A.B. Jamjoom, Josephine Jung, Simon Lammy, Savva Pronin, Cathal J. Hannan, Anna Watts, Laura Hughes, Richard D.C. Moon, Stacey Darwish, Holly Roy, Phillip C. Copley, Michael T.C. Poon, Paul Thorpe, Nisaharan Srikandarajah, Gordan Grahovac, Andreas K. Demetriades, Niall Eames, Philip J. Sell, Patrick F.X. Statham, Mohamed Abdelsadg, Motaz MS Abulaila, Usman Ahmed, Qasim Ajmi, Rafid Al-Mahfoudh, Chadi Ali, Meriem Amarouche, Amin Andalib, M Arora, M Arora, Mariam Awan, Mirza A Baig, Antony Bateman, Iwan Bennett, Imran Bhatti, Peter Bodkin, Lalasa Bommireddy, George Bonanos, Anouk Borg, Alexandros Boukas, James Bourne, Rachael Brennan, J Brown, K Brown, Oliver Burton, Christopher Busby, Neil Chiverton, Simon Clark, Phillip C. Copley, S Cudlip, Y Cunningham, R Dardis, Stacey Darwish, B Davies, Andreas K. Demetriades, S Deore, C Derham, M Dherijha, G Dobson, J Duncan, A Durnford, AZE Durst, EW Dyson, Niall Eames, Ellie Edlmann, A Edwards-Bailey, A Elserius, B Elson, V Fadelalla, DM Fountain, A Gardner, A Ghosh, JR Gill, SA Glasmacher, R Gordon, Gordan Grahovac, R Grenfell, A Habeebullah, N Haliasos, T Hammett, Cathal J. Hannan, CS Hill, Ingrid Hoeritzauer, D Holmes, K Hossain-Ibrahim, Laura Hughes, M Hussain, S Hussain, and R Ibrahim

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Review and update of the Health of the Nation Outcome Scales for People with Learning Disabilities (HoNOS-LD), Jon Painter, Nicola Adams, Barry Ingham, Michael James, Madiha Majid, Ashok Roy, Rohit Shankar, and Mark Smith

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Survey of parents of children with intellectual disabilities and/or autism who experience chronic constipation, Rohit Shankar, James Rooney, Rebecca Hodge, Jade Smith, Kelly Vanstone, and Richard Laugharne

Submissions from 2022

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Evincing Offence: How Digital Forensics Turns Big Data into Evidence for Policing Sexual Abuse, Brian Rappert, Dana Wilson-Kovacs, Hannah Wheat, and Sabina Leonelli

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Management of transgender patients in critical care, L Flower, A Cheung, S Connal, and et al

Nature of β-1,3-Glucan-Exposing Features on Candida albicans Cell Wall and Their Modulation, Leandro Jose De Assis, JM Bain, C Liddle, I Leaves, C Hacker, da Silva R Peres, R Yuecel, A Bebes, D Stead, DS Childers, A Pradhan, K Mackenzie, K Lagree, DE Larcombe, Q Ma, GM Avelar, MG Netea, LP Erwig, AP Mitchell, GD Brown, NAR Gow, and AJP Brown

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Taking the biscuit: defining excessive quantities of free refreshments in a healthcare library, Andrew Tabner, Stuart G. Spicer, Kerryn Husk, Holly Blake, Caroline White, Suzanne Toft, and Graham Johnson

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Withdrawing Antipsychotics for Challenging Behaviours in Adults with Intellectual Disabilities: Experiences and Views of Prescribers, G de Kuijper, J de Haan, S Deb, and R Shankar

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Withdrawing Antipsychotics for Challenging Behaviours in Adults with Intellectual Disabilities: Experiences and Views of Prescribers, Gerda de Kuijper, Joke de Haan, Shoumitro Deb, and Rohit Shankar

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Traditional Beliefs, Practices, and Migration: A Risk to Malaria Transmission in Rural Nepal, KR Awasthi, J Jancey, ACA Clements, RK Sah, and et al

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Barriers to healthcare and their relationship to well-being and social support for autistic adults during COVID-19, Charlotte Featherstone, Richard A. Sharpe, Nick Axford, Sheena Asthana, Susan Ball, and Kerryn Husk

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Antidepressants Trial in Parkinson's Disease (ADepT-PD): protocol for a randomised placebo-controlled trial on the effectiveness of escitalopram and nortriptyline on depressive symptoms in Parkinson’s disease, A. Schrag, C. Carroll, G. Duncan, S. Molloy, L. Grover, R. Hunter, R. Brown, N. Freemantle, J. Whipps, M. A. Serfaty, and G. Lewis

Evaluation of Simvastatin as a Disease-Modifying Treatment for Patients With Parkinson Disease: A Randomized Clinical Trial, Camille Carroll, Kara N. Stevens, Siobhan Creanor, Alison Jeffery, Alan Whone, John Zajicek, Andy Foggo, Ben Jones, Rebecca Chapman, Laura Cocking, Jonny Wilks, and Doug Webb

F-box receptor mediated control of substrate stability and subcellular location organizes cellular development of Aspergillus nidulans, Bayram Ö Sarikaya, Ö Bayram, B Karahoda, C Meister, AM Köhler, S Thieme, N Elramli, D Frawley, J McGowan, DA Fitzpatrick, K Schmitt, Leandro Jose De Assis, O Valerius, GH Goldman, and GH Braus

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Exploring right ventricular function applicability in a prediction model to identify preterm infants with early bronchopulmonary dysplasia (REPORT-BPD study): a mixed-methods observational cohort feasibility study protocol, Wisam S. Muhsen, Eirik Nestaas, Joanne Hosking, and Jos Latour

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Brief opportunistic interventions by general practitioners to promote smoking cessation: a conversation analytic study, H. Wheat, R. K. Barnes, P. Aveyard, F. Stevenson, and R. Begh

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Heat shock protein amplification improves cerebellar myelination in the Npc1nih mouse model, James Gray, María E. Fernández-Suárez, Maysa Falah, D Smith, C Smith, Ecem Kaya, Ashley M. Palmer, Cathrine K. Fog, Thomas Kirkegaard, and Frances M. Platt

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Neural network detection of pacemakers for MRI safety, M Thurston, H Wit, and D Kim

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Novel DNM1L variants impair mitochondrial dynamics through divergent mechanisms, JDC Pereira Baptista

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What matters most to adults with a tracheostomy in ICU and the implications for clinical practice: a qualitative systematic review and metasynthesis, Helen Newman, Gemma Clunie, Sarah Wallace, Christina Smith, Daniel Martin, and Natalie Pattison

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Remote care in UK general practice: baseline data on 11 case studies, T Greenhalgh, SE Shaw, Nishio A Alvarez, R Byng, A Clarke, F Dakin, S Faulkner, N Hemmings, L Husain, A Kalin, E Ladds, L Moore, R Rosen, S Rybczynska-Bunt, J Wherton, and S Wieringa

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Withdrawing Antipsychotics for Challenging Behaviours in Adults with Intellectual Disabilities: Experiences and Views of Experts by Experience, G de Kuijper, J de Haan, S Deb, and R Shankar

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Withdrawing Antipsychotics for Challenging Behaviours in Adults with Intellectual Disabilities: Experiences and Views of Experts by Experience, Gerda de Kuijper, Joke de Haan, Shoumitro Deb, and Rohit Shankar

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What multi-disciplinary delivery models for Occupational Health services are effective for whom? An umbrella review, Elizabeth Shaw, M Nunns, Stuart Spicer, Hassanat Lawal, G. J. Melendez-Torres, Ruth Garside, Kristin Liabo, and J Thompson-Coon

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Monogenic causes of Premature Ovarian Insufficiency are rare and mostly recessive, S Shekari, S Stankovic, EJ Gardner, G Hawkes, KA Kentistou, RN Beaumont, A Mörseburg, AR Wood, G Mishra, F Day, J Baptista, CF Wright, MN Weedon, E Hoffmann, KS Ruth, K Ong, JRB Perry, and A Murray

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The Liverpool alcohol‐related liver disease algorithm identifies twice as many emergency admissions compared to standard methods when applied to Hospital Episode Statistics for England, Ashwin Dhanda, Keith Bodger, Steve Hood, Clive Henn, Michael Allison, Chioma Amasiatu, Robyn Burton, Matthew Cramp, Ewan Forrest, Meetal Khetani, Alastair MacGilchrist, Steven Masson, Richard Parker, Nick Sheron, Ken Simpson, Nikhil Vergis, Martin White, Ahmed Saleh, Alex Boyd, Alison Brind, Alka Joshi, Angie Rund, Ankur Srivastava, Anne McCune, Anthony Gartland, Ben Hudson, Bill Stableforth, Christopher John, Ema Maxan, Esther Unitt, Frederica Beetteridge, Heather Lewis, Helen Fellows, Ihteshamul Haq, Janisha Patel, Jennifer Ryan, Jeremy Cobbold, Keith Pohl, Kevin Raeburn, Lynsey Corless, and Michael Johnston

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The role of mindfulness training in sustaining weight reduction: retrospective cohort analysis, Rohit Shankar, Petra Hanson, Maria Lange, Dominic Oduro-Donkor, Emma Shuttlewood, Martin O. Weickert, Harpal S. Randeva, Vinod Menon, Regi T. Alexander, Paul Basset, and Tom M. Barber

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Examining Quality, Use and Impact of Psychotropic (Use) in older adults with intellectual disabilities (EQUIP): study protocol: Original, Ashleigh Gorman, Rohit Shankar, Marina Odalović, Philip McCallion, Éilish Burke, Malcolm Maclachlan, Mary McCarron, Martin Henman, Maeve Moran, Juliette O'Connell, Mike Walsh, and Marie O'Dwyer

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Oral microbes and the formation of cerebral abscesses: a single-centre retrospective study, Holly Roy, Raul Bescos, Ewen McColl, Umar Rehman, Elizabeth Cray, Louise A. Belfield, King David Nweze, Kevin Tsang, William Singleton, Peter Whitfield, and Zoe Brookes

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The role of mindfulness training in sustaining weight reduction: retrospective cohort analysis, P Hanson, M Lange, D Oduro-Donkor, E Shuttlewood, and et al

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Antihypertensives in dementia: Good or bad for the brain?, Lucy Beishon, Victoria J. Haunton, and Ronney B. Panerai

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Understanding how language revitalisation works: a realist synthesis, Brandon Wiltshire, Steven Bird, and Rebecca Hardwick

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Digital Peer-Supported Self-Management Intervention Codesigned by People With Long COVID: Mixed Methods Proof-of-Concept Study, H Wright, A Turner, S Ennis, C Percy, and et al

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Publisher Correction: Brain charts for the human lifespan, RAI Bethlehem, J Seidlitz, SR White, and et al

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Real-world effectiveness of pneumococcal vaccination in older adults: Cohort study using the UK Clinical Practice Research Datalink, AJ Streeter, LR Rodgers, J Masoli, NX Lin, A Blé, W Hamilton, and WE Henley

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The economic case for hospital discharge services for people experiencing homelessness in England: An in‐depth analysis with different service configurations providing specialist care, Michela Tinelli, Raphael Wittenberg, Michelle Cornes, Robert W. Aldridge, Michael Clark, Richard Byng, Graham Foster, James Fuller, Andrew Hayward, Nigel Hewett, Alan Kilmister, Jill Manthorpe, Joanne Neale, Elizabeth Biswell, and Martin Whiteford

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A paperless approach to clinical trial systems: from specification to validation and beyond., MP Bailey, H Abraham, D Maddock, R Ashford, and C Hayward

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Social prescribing for children and young people, Marcello Bertotti, Dan Hayes, Vashti Berry, Paul Jarvis-Beesley, and Kerryn Husk

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Could a Medication Help With Bleeding Between the Skull and the Brain?, A Chari, KS Lee, A Alamri, PJA Hutchinson, AG Kolias, and E Edlmann

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Comment on: Disease gene identification strategies for exome sequencing by Gilissen et al. 2012, Julia Baptista

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Cost-effectiveness of mirtazapine for agitated behaviors in dementia: findings from a randomized controlled trial, Catherine Henderson, Martin Knapp, Susan Stirling, Lee Shepstone, Juliet High, Clive Ballard, Peter Bentham, Alistair Burns, Nicolas Farina, Chris Fox, Julia Fountain, Paul Francis, Robert Howard, Iracema Leroi, Gill Livingston, Ramin Nilforooshan, Shirley Nurock, JT O’Brien, Annabel Price, Ann Marie Swart, Naji Tabet, Tanya Telling, Alan J. Thomas, and Sube Banerjee

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Development and evaluation of a collaborative care intervention for male prison leavers with mental health problems: the Engager research programme, Richard Byng, Charlotte Lennox, Tim Kirkpatrick, Cath Quinn, Rob Anderson, Sarah Louise Brand, Lynne Callaghan, Lauren Carroll, Graham Durcan, Laura Gill, Sara Goodier, Jonathan Graham, Rebecca Greer, Mark Haddad, Tirril Harris, William Henley, Rachael Hunter, Mike Maguire, Sarah Leonard, Susan Michie, Christabel Owens, Mark Pearson, Sarah Rybczynska-Bunt, Caroline Stevenson, Amy Stewart, Alex Stirzaker, Rod Taylor, Roxanne Todd, Florian Walter, Fiona C. Warren, Lauren Weston, Nat Wright, and Jenny Shaw

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Progress and challenges in the harmonisation of European undergraduate dental education: a systematic literature review with narrative synthesis., Marie Bryce, Daniel Zahra, Lorna Burns, Sally Hanks, and Thomas Gale

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Traboulsi syndrome caused by mutations in ASPH: An autosomal recessive disorder with overlapping features of Marfan syndrome, Gabriela Jones, Katie Johnson, Jacqueline Eason, Mark Hamilton, Deborah Osio, Farah Kanani, Julia Baptista, and Mohnish Suri

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Direct isolation of single cells from living brains of Drosophila melanogaster without dissociation for transcriptome analysis, Claudia S. Barros and Torsten Bossing

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A process evaluation, with mediation analysis, of a web-based intervention to augment primary care exercise referral schemes: the e-coachER randomised controlled trial, Jeffrey Lambert, A Taylor, Adam Streeter, Colin Greaves, Wendy M. Ingram, Sarah Dean, Kate Jolly, Nanette Mutrie, RS Taylor, Lucy Yardley, Lisa Price, and John Campbell

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Tauroursodeoxycholic acid in patients with amyotrophic lateral sclerosis: The TUDCA-ALS trial protocol, Alberto Albanese, TUDCA-ALS Study Group, Albert Christian Ludolph, Christopher J. McDermott, Philippe Corcia, Philip Van Damme, Leonard H. Van den Berg, Orla Hardiman, Gilberto Rinaldi, Nicola Vanacore, Brian Dickie, Paolo Tornese, Antoniangela Cocco, Maria Lo Giudice, Michela Matteoli, Eliana Lauranzano, Maria Luisa Malosio, Chiara Adriana Elia, Flavia Lombardo, Flavia Mayer, Maria Puopolo, Stefania Spila Alegiani, Adriano Chiò, Umberto Manera, Cristina Moglia, Andrea Calvo, Paolina Salamone, Giuseppe Fuda, Carlo Colosimo, Cristina Spera, Giuseppe Stipa, Domenico Frondizi, Christian Lunetta, Valeria Sansone, Claudia Tarlarini, Francesca Gerardi, Vincenzo Silani, Alberto Doretti, Eleonora Colombo, Gianluca Demirtzidis, Gioacchino Tedeschi, Francesca Trojsi, Carla Passaniti, Stefania Ballestrero, Johannes Dorst, Ulrike Weiland, Andrea Fromm, Maximilian Wiesenfarth, Katharina Kandler, Simon Witzel, and Oliver Hanemann

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Inhibition of YAP/TAZ-driven TEAD activity prevents growth of NF2-null schwannoma and meningioma, David B. Parkinson

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A Tailored Approach: A model for literature searching in complex systematic reviews, Chris Cooper, Andrew Booth, Kerryn Husk, Rebecca Lovell, Julia Frost, Ute Schauberger, Nicky Britten, and Ruth Garside

Hemocytes are essential for Drosophila melanogaster post-embryonic development, independent of control of the microbiota, Alf Herzig, Holly N. Stephenson, Robert Streeck, Florian Grüblinger, and Christian Goosmann

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A group-based behavioural intervention for weight management (PROGROUP) versus usual care in adults with severe obesity: a feasibility randomised controlled trial protocol, Dawn Swancutt, Mark Tarrant, Wendy Ingram, Sarah Baldrey, Lorna Burns, Richard Byng, Raff Calitri, Siobhan Creanor, Sarah Dean, Lucy Evans, Laura Gill, Elizabeth Goodwin, Lily Hawkins, Chris Hayward, Sarah Hind, Laura Hollands, Joanne Hosking, Jenny Lloyd, Shokraneh Moghadam, Helen Neilens, Mary O’Kane, Steve Perry, Rod Sheaff, Anne Spencer, Adrian Taylor, Thomas Ward, Ross Watkins, John Wilding, and Jonathan Pinkney

Incisional hernia following colorectal cancer surgery according to suture technique: Hughes Abdominal Repair Randomized Trial (HART), J Torkington, R. Harries, S. O'Connell, L. Knight, S. Islam, N. Bashir, A. Watkins, G. Fegan, J. Cornish, B. Rees, H. Cole, H. Jarvis, S Jones, I. Russell, D. Bosanquet, A. Cleves, B. Sewell, A. Farr, N. Zbrzyzna, N. Fiera, R. Ellis-Owen, Z Hilton, C. Parry, A. Bradbury, P. Wall, J. Hill, D. Winter, K. Cocks, D. Harris, and J Hilton

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Dexamethasone reduces vascular endothelial growth factor in comparison to placebo in post-operative chronic subdural hematoma samples: A target for future drug therapy?, Ellie Edlmann, Susan Giorgi-Coll, Eric P. Thelin, Peter J. Hutchinson, and Keri L.H. Carpenter

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Germline homozygous missense DEPDC5 variants cause severe refractory early-onset epilepsy, macrocephaly and bilateral polymicrogyria, Athina Ververi, Sara Zagaglia, Lara Menzies, Julia Baptista, Richard Caswell, Stephanie Baulac, Sian Ellard, Sally Lynch, Thomas S. Jacques, Maninder Singh Chawla, Martin Heier, Mari Ann Kulseth, Inger Lise Mero, Anne Katrine Våtevik, Ichraf Kraoua, Rhouma H Ben, Younes T Ben, Zouhour Miladi, Youssef Turki I Ben, Wendy D. Jones, Emma Clement, Christin Eltze, Kshitij Mankad, Ashirwad Merve, Jennifer Parker, Bethan Hoskins, Ronit Pressler, Sniya Sudhakar, Catherine Devile, Tessa Homfray, Marios Kaliakatsos, Robert Robinson, Sara Margrete Bøen Keim, Imen Habibi, Alexandre Reymond, Sanjay M. Sisodiya, and Jane A. Hurst

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Germline homozygous missense DEPDC5 variants cause severe refractory early-onset epilepsy, macrocephaly and bilateral polymicrogyria, A Ververi, S Zagaglia, SM Sisodiya, JA Hurst, and et al

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Multiplex Lateral Flow Assay and the Sample Preparation Method for the Simultaneous Detection of Three Marine Toxins, Clare Mills, Michael J. Dillon, Prabir Kumar Kulabhusan, Diana Senovilla-Herrero, and Katrina Campbell

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A systematic review identifying outcome measures used in evaluating adults sustaining cervical spine fractures, Phillip C. Copley, Daniel Tadross, Nadia Salloum, Julie Woodfield, Ellie Edlmann, Michael Poon, Sadaquate Khan, and Paul M. Brennan

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‘Pushing back’: People newly diagnosed with dementia and their experiences of the Covid‐19 pandemic restrictions in England, J Dixon, B Hicks, K Gridley, R Perach, and et al

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Adaptation of the STRiDE dementia survey into the Indonesian context in North Sumatra, Fasihah Irfani Fitri, Ika Mariana Gultom, Eka Mahendrayana, Engki Irawan, Aldy S. Rambe, Tara Puspitarini Sani, Yuda Turana, Imelda Theresia, Nicolas Farina, and Sube Banerjee

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Bi-allelic LETM1 variants perturb mitochondrial ion homeostasis leading to a clinical spectrum with predominant nervous system involvement, JDC Pereira Baptista

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Cataract, abnormal electroretinogram and visual evoked potentials in a child with SMA-LED2 - extending the phenotype, Agata Oliwa, Shuko Joseph, Eoghan Millar, Iain Horrocks, Dawn Penman, Julia Baptista, Thomas Cullup, Panayiotis Constantinou, Anne Marie Heuchan, Ruth Hamilton, and Cheryl Longman

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Early computed tomography coronary angiography in adults presenting with suspected acute coronary syndrome: the RAPID-CTCA RCT, Alasdair J. Gray, Carl Roobottom, Jason E. Smith, Steve Goodacre, Katherine Oatey, Rachel O’Brien, Robert F. Storey, Nick Curzen, Liza Keating, Attila Kardos, Dirk Felmeden, Robert J. Lee, Praveen Thokala, Steff C. Lewis, and David E. Newby

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Pharmacogenomics: an opportunity for personalised psychotropic prescribing in adults with intellectual disabilities, B Perera, C Steward, K Courtenay, T Andrews, and R Shankar

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Rapid exome sequencing in critically ill children impacts acute and long-term management of patients and their families: a retrospective regional evaluation, JDC Pereira Baptista

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Optimising a person-centred approach to stopping medicines in older people with multimorbidity and polypharmacy using the DExTruS framework: a realist review, Amadea Turk, Geoffrey Wong, Kamal R. Mahtani, Michelle Maden, Ruaraidh Hill, Ed Ranson, Emma Wallace, Janet Krska, Dee Mangin, Richard Byng, Daniel Lasserson, and Joanne Reeve

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Virtual Care and the Inverse Care Law: Implications for Policy, Practice, Research, Public and Patients, H Alami, P Lehoux, SE Shaw, and et al

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Mixed-methods feasibility cluster randomised controlled trial of a paramedic-administered breathlessness management intervention for acute-on-chronic breathlessness (BREATHE): Study findings, Ann Hutchinson, Victoria Allgar, Judith Cohen, David C. Currow, Susan Griffin, Simon Hart, Kelly Hird, Andrew Hodge, Suzanne Mason, Matthew Northgraves, Joanne Reeve, Flavia Swan, and Miriam J. Johnson

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Tailoring cultural offers to meet the needs of older people during uncertain times: a rapid realist review, Stephanie Tierney, Sebastien Libert, Jordan Gorenberg, Geoff Wong, Amadea Turk, Kerryn Husk, Helen J. Chatterjee, Kathryn Eccles, Caroline Potter, Emma Webster, Beth McDougall, Harriet Warburton, Lucy Shaw, Nia Roberts, and Kamal R. Mahtani

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Personalising knowledge assessments to remove compensation and thereby improve preparation for safe practice - developing content adaptive progress testing, S Burr, J Kisielewska, D Zahra, I Hodgins, I Robinson, P Millin, T Gale, N Santos, and J Pêgo

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Antidepressant prescribing for adult people with an intellectual disability living in England, Rohit Shankar and David Branford

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Evaluation of a complex intervention for prisoners with common mental health problems, near to and after release: the Engager randomised controlled trial, Richard Byng, Tim Kirkpatrick, Charlotte Lennox, Fiona C. Warren, Rob Anderson, Sarah Louise Brand, Lynne Callaghan, Lauren Carroll, Graham Durcan, Laura Gill, Sara Goodier, Jonathan Graham, Rebecca Greer, Mark Haddad, Tirril Harris, William Henley, Rachael Hunter, Sarah Leonard, Mike Maguire, Susan Michie, Christabel Owens, Mark Pearson, Cath Quinn, Sarah Rybczynska-Bunt, Caroline Stevenson, Amy Stewart, Alex Stirzaker, Roxanne Todd, Florian Walter, Lauren Weston, Nat Wright, Rod S. Taylor, and Jenny Shaw

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Pharmacogenomics: An opportunity for personalised psychotropic prescribing in adults with intellectual disabilities, Rohit Shankar, Bhathika Perera, Charles Steward, Ken Courtenay, and Timothy Andrews

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Effectiveness of a targeted telephone-based case management service on activity in an Emergency Department in the UK: a pragmatic difference-in-differences evaluation, Julian Elston, Felix P. Gradinger, Adam J. Streeter, Stephen Macey, and Susan Martin

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Outcome and mortality of hospital admission with COVID-19 for individuals with parkinsonian syndromes, L Sorrell, A King, J Inches, J Rideout, JR Sneyd, C Kobylecki, R Chaudhuri, R Walker, H Martin, and C Carroll

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Longitudinal expression profiling identifies a poor risk subset of patients with ABC-type Diffuse Large B Cell Lymphoma, F Bewicke-Copley, K Korfi, S Araf, and et al