Browse research from the Peninsula Medical School.

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Submissions from 2021

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X-linked Ohdo syndrome due to a novel MED12 variant detected by Rapid Exome Sequencing, Helen McDermott, Vidya Garikapati, Júlia Baptista, Harsha Gowda, and Swati Naik

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Divergent trajectories of cellular bioenergetics, intermediary metabolism and systemic redox status in survivors and non-survivors of critical illness, Helen T. McKenna, KA O’Brien, Bernadette O. Fernandez, Magdalena Minnion, Adam Tod, Ben D. McNally, James A. West, Julian L. Griffin, Michael P. Grocott, Michael G. Mythen, Martin Feelisch, Andrew J. Murray, and Daniel S. Martin

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Modern cemented Furlong hemiarthroplasty: Are dislocations rates better?, C. U. Menakaya, M. Shah, H. Ingoe, R. Malhotra, A. Mannan, T. Boddice, V. Allgar, S. Gopal, A. Mohsen, and N. Muthukumar

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Editorial: can quantitative fibrosis assessment be used to enhance prediction of outcomes in patients with alcohol-related liver disease?, Prebashan Moodley and Ashwin D. Dhanda

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Recurrent Chronic HEV in Severe Combined Immunodeficiency, Prebashan Moodley, Andrew F. Whyte, and Ashwin Dhanda

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Sex-based inequalities in contemporary UK hospital management of stable chest pain, Gareth Morgan-Hughes, Michelle Claire Williams, Margaret Loudon, Carl A. Roobottom, Stelios Iacovides, Franchesca Wotton, Alice Veitch, M Schmitt, and Russel Bull

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Downstream testing after CT coronary angiography: time for a rethink?, Gareth Morgan-Hughes, Michelle Claire Williams, Margaret Loudon, Carl A. Roobottom, Alice Veitch, Lingen R Van, Ben Holloway, Nicholas Bellenger, Matthias Schmitt, and Russel Bull

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Interleukin-2 receptor antibody induction with early low dose tacrolimus preserves post-liver transplant renal function in at risk individuals, JS Nayagam, OD Tavabie, B Norton, MJS McMahon, K Ramos, ISH Cadden, ME Cramp, K Menon, A Prachalias, K Agarwal, MA Heneghan, D Joshi, and VR Aluvihare

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Tangrams: a simple visual tool for communicating the complexities of professionalism, H Neve and S Hanks

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It’s the attraction of winning that draws you in” – A qualitative investigation of reasons and facilitators for videogame loot box engagement in UK gamers, Laura Louise Nicklin, Stuart Gordon Spicer, James Close, Jonathan Parke, Oliver Smith, T Rayman, H Lloyd, and J Lloyd

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A clinical study to optimise a sand fly biting protocol for use in a controlled human infection model of cutaneous leishmaniasis (the FLYBITE study), Vivak Parkash, Helen Ashwin, Jovana Sadlova, Barbora Vojtkova, Georgina Jones, Nina Martin, Elizabeth Greensted, Victoria Allgar, Shaden Kamhawi, Jesus G. Valenzuela, Alison M. Layton, Charles L. Jaffe, Petr Volf, Paul M. Kaye, and Charles J.N. Lacey

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Trajectory of Serum Bilirubin Predicts Spontaneous Recovery in a Real-World Cohort of Patients With Alcoholic Hepatitis, Richard Parker, Joaquin Cabezas, Jose Altamirano, Juan Pablo Arab, Meritxell Ventura-Cots, Ashish Sinha, Ashwin Dhanda, Marco Arrese, C. Anne McCune, Ian A. Rowe, Bernd Schnabl, Phillipe Mathurin, Debbie Shawcross, Juan G. Abraldes, Michael R. Lucey, Guadalupe Garcia-Tsao, Elizabeth Verna, Robert S. Brown, Francisco Bosques-Padilla, Victor Vargas, Alexandre Louvet, Andrew P. Holt, and Ramon Bataller

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Investigating smoking and nicotine dependence among people with severe mental illness during the COVID-19 pandemic: analysis of linked data from a UK Closing the Gap cohort, Emily Peckham, Victoria Allgar, Suzanne Crosland, Paul Heron, Gordon Johnston, Elizabeth Newbronner, Elena Ratschen, Panagiotis Spanakis, Ruth Wadman, Lauren Walker, and Simon Gilbody

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Assessment of hepatic steatosis by controlled attenuation parameter using the M and XL probes: an individual patient data meta-analysis, David Petroff, Valentin Blank, Philip N. Newsome, N/A Shalimar, Cosmin Sebastian Voican, Maja Thiele, Lédinghen V de, Stephan Baumeler, Wah Kheong Chan, Gabriel Perlemuter, Ana Carolina Cardoso, Sandeep Aggarwal, Magali Sasso, Peter J. Eddowes, Michael Allison, Emmanuel Tsochatzis, Quentin M. Anstee, David Sheridan, Jeremy F. Cobbold, Sylvie Naveau, Monica Lupsor-Platon, Sebastian Mueller, Aleksander Krag, Marie Irles-Depe, David Semela, GL-H Wong, VW-S Wong, Cristiane A. Villela-Nogueira, Harshit Garg, Olivier Chazouillères, Johannes Wiegand, and Thomas Karlas

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Adapting and validating the Autism Diagnostic Observation Schedule Version 2 for use with deaf children and young people, Helen Phillips, Barry Wright, Victoria Allgar, Helen McConachie, Jennifer Sweetman, Rebecca Hargate, Rachel Hodkinson, Martin Bland, Hannah George, Anna Hughes, Emily Hayward, Las Heras VFG De, and Couteur A Le

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Evaluation of a primary care-based collaborative care model (PARTNERS2) for people with diagnoses of schizophrenia, bipolar, or other psychoses: study protocol for a cluster randomised controlled trial, Humera Plappert, Charley Hobson-Merrett, Bliss Gibbons, Elina Baker, Sheridan Bevan, Michael Clark, Siobhan Creanor, Linda Davies, Rebecca Denyer, Julia Frost, Linda Gask, John Gibson, Laura Gill, Ruth Gwernan-Jones, Pollyanna Hardy, Joanne Hosking, Peter Huxley, Alison Jeffrey, Benjamin Jones, Steven Marwaha, Vanessa Pinold, Claire Planner, Tim Rawcliffe, Siobhan Reilly, Debra Richards, Lynsey Williams, Max Birchwood, and Richard Byng

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Mental Health and Wellbeing in Dentistry: A Rapid Evidence Assessment, Anastasios Plessas, Martha Paisi, Marie Bryce, Lorna Burns, Timothy O'Brien, Robert Witton, and Yaniv Hanoch

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Alcohol’s Impact on the Gut and Liver, Keith Pohl, Prebashan Moodley, and Ashwin D. Dhanda

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Optimising the delivery of remediation programmes for doctors: A realist review, Tristan Price, Geoff Wong, Lyndsey Withers, Amanda Wanner, Jennifer Cleland, Tom Gale, L Prescott‐Clements, Julian Archer, Marie Bryce, and Nicola Brennan

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Status of primary and secondary mental healthcare of people with severe mental illness: an epidemiological study from the UK PARTNERS2 programme, Siobhan Reilly, Catherine McCabe, Natalie Marchevsky, Maria Green, Linda Davies, Natalie Ives, Humera Plappert, Jon Allard, Tim Rawcliffe, John Gibson, Michael Clark, Vanessa Pinfold, Linda Gask, Peter Huxley, Richard Byng, and Max Birchwood

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The impact of smoking cessation on multiple sclerosis disease progression, Jeff Rodgers, Tim Friede, Frederick W. Vonberg, Cris S. Constantinescu, Alasdair Coles, Jeremy Chataway, Martin Duddy, Hedley Emsley, H Ford, Leonora Fisniku, Ian Galea, Timothy Harrower, Jeremy Hobart, Huseyin Huseyin, Christopher M. Kipps, Monica Marta, Gavin V. Mcdonnell, Brendan Mclean, Owen R. Pearson, David Rog, Klaus Schmierer, Basil Sharrack, Agne Straukiene, Heather C. Wilson, DV Ford, Rod M. Middleton, and Richard Nicholas

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Impact of influenza vaccination on amoxicillin prescriptions in older adults: A retrospective cohort study using primary care data, LR Rodgers, AJ Streeter, N Lin, W Hamilton, and WE Henley

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Clarifying realist analytic and interdisciplinary consensus processes in a complex health intervention: A worked example of Judgemental Rationality in action, Sarah Rybczynska-Bunt, Lauren Weston, Richard Byng, Alex Stirzaker, Charlotte Lennox, Mark Pearson, Sarah Brand, Mike Maguire, Graham Durcan, Jonathan Graham, Sarah Leonard, Jenny Shaw, Tim Kirkpatrick, Christabel Owens, and Cath Quinn

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Factors Associated With Relapse and Treatment of Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease in the United Kingdom, Chanjira Satukijchai, Romina Mariano, Silvia Messina, Mario Sa, Mark R. Woodhall, Neil P. Robertson, Lim Ming, Evangeline Wassmer, Rachel Kneen, Saif Huda, Anu Jacob, Camilla Blain, Christopher Halfpenny, Cheryl Hemingway, Eoin O'Sullivan, Jeremy Hobart, Leonora K. Fisniku, Roswell Martin, Ruth Dopson, Sarah A. Cooper, Victoria Williams, Patrick J. Waters, Sithara Ramdas, MI Leite, and Jacqueline Palace

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Categories of context in realist evaluation, Rod Sheaff, Natasha Doran, Michael Harris, Iain Lang, Antionieta Medina-Lara, Mauro Fornasiero, Susan Ball, Judith McGregor-Harper, and Rob Bethune

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The current status of perioperative hypnotics, the role of benzodiazepines and the case for remimazolam, J Sneyd, P Gambus, and A Rigby-Jones

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Biomarkers for differentiating grade II meningiomas from grade I, Agbolahan A. Sofela, Lucy McGavin, Peter C. Whitfield, and C. Oliver Hanemann

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Estimating the correlation between semi-competing risk survival endpoints, Lexy Sorrell, Yinghui Wei, M Wojtys, and Peter Rowe

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Representing uncertainty in the Rescorla-Wagner model: Blocking, the redundancy effect, and outcome base rate, SG Spicer, AJ Wills, PM Jones, CJ Mitchell, and L Dome

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Theory protection: do humans protect existing associative links?, Stuart G. Spicer, Chris J. Mitchell, Andy J. Wills, Katie L. Blake, and Peter M. Jones

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Loot boxes, problem gambling and problem video gaming: A systematic review and meta-synthesis, Stuart Gordon Spicer, N Laura, L Joanne, U Maria, H Lloyd, and James Close

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Clival Mucocele: A Rare Yet not Forgotten Pathology, M Stavrakas, HS Khalil, N Tsetsos, and S Muquit

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Bayesian statistics in the design and analysis of cluster randomised controlled trials and their reporting quality: a methodological systematic review, Adam J. Streeter, Amy Baker, Rana Moyeed, and Siobhan Creanor

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Challenges and opportunities in the care of chronic subdural haematoma: perspectives from a multi-disciplinary working group on the need for change, DJ Stubbs, B Davies, P Hutchinson, DK Menon, TH Bashford, E Edlmann, A Bateman, P Braude, R Burnstein, S Camp, G Carr, PJ Clarkson, J Coles, J Dhesi, J Dinsmore, M Dixon-Woods, A Ercole, N Evans, A Figaji, S Griffin, P Grundy, P Hartley, A Joannides, A Kolias, F Lecky, P May, I Moppett, S Morris, M Nathanson, J Outtrim, N Owen, N Phillips, T Quinn, S Ralhan, D Sapsford, DJH Shipway, C Skitterall, M Smith, M Swart, W Thomas, K Walton, N Wareham, P Whitfield, SR Wilson, and M Vindlacheruvu

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GP trainee responses to using SHERPA for multimorbidity consultations, Dawn R. Swancutt, Edmund Jack, Hilary A. Neve, John Tredinnick-Rowe, Nick Axford, and Richard Byng

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Mental Health and Physical Activity, yoga and other holistic movement practices (HMPs): A position statement, Adrian Taylor, Ana Abrantes, Mats Hallgren, Matthew Herring, Caterina Pesce, Simon Rosenbaum, and Megan Teychenne

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Editorial: Extending the evidence for if and how physical activity can support positive changes among substance users, Adrian H. Taylor, Tom P. Thompson, Ana Abrantes, and Mats Hallgren

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TARS Health Trainer Manual, T Thompson, A Taylor, L Callaghan, and C Greaves

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Intronic Haplotypes in the GBA Gene Do Not Predict Age at Diagnosis of Parkinson's Disease, Marco Toffoli, Abigail Higgins, Chiao Lee, Sofia Koletsi, Xiao Chen, Michael Eberle, Fritz J. Sedlazeck, Stephen Mullin, Christos Proukakis, and Anthony H.V. Schapira

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Identification of deliberate catheter motion at the left atrial posterior wall during pulmonary vein isolation: Validity of respiratory motion adjustment, DR Tomlinson, K Biscombe, J true, J Hosking, and AJ Streeter

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The caspase-6–p62 axis modulates p62 droplets based autophagy in a dominant-negative manner, Evelina Valionyte, Yi Yang, Sophie A. Griffiths, Amelia T. Bone, Elizabeth R. Barrow, Vikram Sharma, Boxun Lu, and Shouqing Luo

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Assessment of cytokines, microRNA and patient related outcome measures in conversion disorder/functional neurological disorder (CD/FND): The CANDO clinical feasibility study, der Feltz-Cornelis C van, Sally Brabyn, Jonathan Ratcliff, Danielle Varley, Victoria Allgar, Simon Gilbody, Chris Clarke, and Dimitris Lagos

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Digital health technology for non-motor symptoms in people with Parkinson's disease: Futile or future?, Wamelen DJ van, Jirada Sringean, Dhaval Trivedi, Camille B. Carroll, Anette E. Schrag, Per Odin, Angelo Antonini, Bastiaan R. Bloem, Roongroj Bhidayasiri, and K. Ray Chaudhuri

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Exenatide once weekly over 2 years as a potential disease-modifying treatment for Parkinson’s disease: protocol for a multicentre, randomised, double blind, parallel group, placebo controlled, phase 3 trial: The ‘Exenatide-PD3’ study, Nirosen Vijiaratnam, Christine Girges, Grace Auld, Marisa Chau, Kate Maclagan, Alexa King, Simon Skene, Kashfia Chowdhury, Steve Hibbert, Huw Morris, Patricia Limousin, Dilan Athauda, Camille B. Carroll, Michele T. Hu, Monty Silverdale, Gordon W. Duncan, Ray Chaudhuri, Christine Lo, Din S Del, Alison J. Yarnall, Lynn Rochester, Rachel Gibson, John Dickson, Rachael Hunter, Vincenzo Libri, and Thomas Foltynie

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A Case of Clinically Diagnosed ANCA Negative Granulomatosis With Polyangiitis, A Walkden, M Salem, M Stavrakas, and H Khalil

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Terms of Engagement for Working with Patients in a Person-Centred Partnership: A Secondary Analysis of Qualitative Data., Debra Westlake and Helen Lloyd

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Treatment threshold for intra‐operative hypotension in clinical practice—a prospective cohort study in older patients in the UK, A. J. Wickham, D. T. Highton, S. Clark, D. Fallaha, D. J.N. Wong, and D. S. Martin

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Adapting and validating the Autism Diagnostic Interview - Revised for use with deaf children and young people, Barry Wright, Helen Phillips, Victoria Allgar, Jennifer Sweetman, Rachel Hodkinson, Emily Hayward, Amelia Ralph-Lewis, Catarina Teige, Martin Bland, and Couteur A Le

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Current state-of-the-art diagnostics for Norovirus detection: Model approaches for point-of-care analysis, Maja A. Zaczek-Moczydlowska, Azadeh Beizaei, Michael Dillon, and Katrina Campbell

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Aesthetically Designing Video-Call Technology With Care Home Residents: A Focus Group Study, Sonam Zamir, Felicity Allman, Catherine Hagan Hennessy, Adrian Haffner Taylor, and Ray Brian Jones

Submissions from 2020

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De-mystifying the ‘Mixifusor’, AR Absalom, A Rigby-Jones, AR Rushton, and J Sneyd

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A Rapid Robust Method for Subgrouping Non-NF2 Meningiomas According to Genotype and Detection of Lower Levels of M2 Macrophages in AKT1 E17K Mutated Tumours, Claire L. Adams, Emanuela Ercolano, Sara Ferluga, Agbolahan Sofela, Foram Dave, Caterina Negroni, Kathreena M. Kurian, David A. Hilton, and C. Oliver Hanemann

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Port dumping and participation in England: Developing an ecosystem approach through local ecological knowledge, Jeremy Anbleyth-Evans, Shaw Nozaki Lacy, Carolina Aguirre-Muñoz, and John Tredinnick-Rowe

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Challenges to well-being for general practice trainee doctors: a qualitative study of their experiences and coping strategies, Sarah Ansell, James Read, and Marie Bryce

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Capturing the role of context in complex system change: an application of the Canadian Context and Capabilities for Integrating Care (CCIC) Framework to the English Context, Sheena Asthana, Felix Gradinger, Julian Elston, Susan Martin, and Richard Byng

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eHealth technologies and the know-do gap: exploring the role of knowledge mobilisation, Sheena Asthana, Rod Sheaff, Ray Jones, and Arunangsu Chatterjee

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Understanding Resource Allocation in social care for frail older people: lessons from a national survey, Sheena Asthana, Karen Stewart, Jane Hughes, David Challis, A Wordon, Sue Davies, Chengqiu Xie, and Alex Gibson

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Promoting learning from null or negative results in prevention science trials, Nick Axford, Vashti Berry, Jenny Lloyd, Tim Hobbs, and Katrina Wyatt

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The effectiveness of the KiVa bullying prevention program in Wales, UK: results from a pragmatic cluster randomised controlled trial, Nick Axford, Gretchen Bjornstad, Suzy Clarkson, Obioha C. Ukoumunne, Zoe Wrigley, Justin Matthews, and Vashti Berry

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The effectiveness of a therapeutic parenting program for children aged 6-11 years with behavioral or emotional difficulties: Results from a randomised controlled trial, Nick Axford, Gretchen Bjornstad, Justin Matthews, Sarah Heilmann, Anam Raja, Obioha C. Ukoumunne, Vashti Berry, Tom Wilkinson, Luke Timmons, Tim Hobbs, Tim Eames, Angeliki Kallitsoglou, Sarah Blower, and Georgina Warner

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The effectiveness of a therapeutic parenting program for children aged 6-11 years with behavioural or emotional difficulties: results from a randomized controlled trial, Nick Axford, Gretchen Bjornstad, Justin Matthews, Sarah Heilmann, Anam Raja, Obioha C. Ukoumunne, Vashti Berry, Tom Wilkinson, Luke Timmons, Tim Hobbs, Tim Eames, Angeliki Kallitsoglou, Sarah Blower, and Georgina Warner

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The Effectiveness of a Community-Based Mentoring Program for Children Aged 5–11 Years: Results from a Randomized Controlled Trial, Nick Axford, Gretchen Bjornstad, Justin Matthews, Laura Whybra, Vashti Berry, Obioha C. Ukoumunne, Tim Hobbs, Zoe Wrigley, Lucy Brook, Rod Taylor, Tim Eames, Angeliki Kallitsoglou, Sarah Blower, and Georgina Warner

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Parkin deficiency perturbs striatal circuit dynamics, Magdalena K. Baaske, Edgar R. Kramer, Durga Praveen Meka, Gerhard Engler, Andreas K. Engel, and Christian K.E. Moll

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Barriers and Enablers in Implementing Electronic Consultations in Primary Care: Scoping Review, Rebecca Baines, John Tredinnick-Rowe, Ray Jones, and Arunangsu Chatterjee

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GDNF and Parkinson’s Disease: Where Next? A Summary from a Recent Workshop, Roger A. Barker, A Bjorklund, Don M. Gash, Alan Whone, Laar A Van, Jeffrey H. Kordower, Krystof Bankiewicz, Karl Kieburtz, Mart Saarma, Sigrid Booms, Henri J. Huttunen, Adrian P. Kells, Massimo S. Fiandaca, A. Jon Stoessl, David Eidelberg, Howard Federoff, Merja H. Voutilainen, David T. Dexter, Jamie Eberling, Patrik Brundin, Lyndsey Isaacs, Leah Mursaleen, Eros Bresolin, Camille Carroll, Alasdair Coles, Brian Fiske, Helen Matthews, Codrin Lungu, Richard K. Wyse, Simon Stott, and Anthony E. Lang

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A Systematic Approach to Review of in vitro Methods in Brain Tumour Research (SAToRI-BTR): Development of a Preliminary Checklist for Evaluating Quality and Human Relevance, Mike Bracher, GJ Pilkington, C. Oliver Hanemann, and K Pilkington

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Assessing the impact of a new central venous access device training program for nurses: A Quasi-Experimental Evaluation study, Wendy Burt and Lucy Spowart

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FGF5 Regulates Schwann Cell Migration and Adhesion, Bing Chen, Rong Hu, Qing Min, Yankun Li, David B. Parkinson, and Xin Peng Dun

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OCD Candidate Gene SLC1A1/EAAT3 Impacts Dopamine Neuron Firing and Behavioral Flexibility, M Chohan, J Kopelman, E Kramer, P Balsam, S Ahmari, and J Veenstra-Vanderweele

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Contrasting impact of androgens on male and female adiposity, fat distribution and insulin resistance in childhood and adolescence (EarlyBird 75), Jade Chynoweth, Joanne Hosking, Alison Jeffery, and Jonathan Pinkney

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Measuring upper limb function in MS: Which existing patient reported outcomes are fit for purpose?, James Close, Kathryn Baines, Laurie Burke, and Jeremy Hobart

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Contributions of Fat and Carbohydrate Metabolism to Glucose Homeostasis in Childhood Change With Age and Puberty: A 12-Years Cohort Study (EARLYBIRD 77), Ornella Cominetti, Joanne Hosking, Alison Jeffery, Jonathan Pinkney, and Francois Pierre Martin

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A comparison of the quality of image acquisition between two different sidestream dark field video-microscopes, Jonny Coppel, Vassiliki Bountziouka, Daniel Martin, and Edward Gilbert-Kawai

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Oxygen targets in the intensive care unit during mechanical ventilation for acute respiratory distress syndrome: a rapid review, Andrew F. Cumpstey, Alex H. Oldman, Andrew F. Smith, Daniel Martin, and Michael P.W. Grocott

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Trace element deficiency is highly prevalent and associated with infection and mortality in patients with alcoholic hepatitis, Ashwin Dhanda, Stephen Atkinson, Nikhil Vergis, Doyo Enki, Andrew Fisher, Robert Clough, Matthew Cramp, and Mark Thursz

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Introducing the Parkinson’s KinetiGraph into Routine Parkinson’s Disease Care: A 3-Year Single Centre Experience, Thea Dominey, Angie A. Kehagia, Terry Gorst, Emma Pearson, Fiona Murphy, Emma King, and Camille Carroll

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Integration and Comparison of Transcriptomic and Proteomic Data for Meningioma, Jemma Dunn, Vasileios P. Lenis, David A. Hilton, Rolf Warta, Christel Herold-Mende, C. Oliver Hanemann, and Matthias E. Futschik

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The changing face of neurosurgery for the older person, Ellie Edlmann and Peter C. Whitfield

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In reply to: Helmich and Bloem (2020) “The Impact of the COVID-19 Pandemic on Parkinson’s Disease: Hidden Sorrows and Emerging Opportunities”, Emma Edwards and Camille Carroll

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Home Based Care: A care pathway innovation for Parkinson's disease, E Edwards, R Partridge, U Ankeny, J Langley, S Whipps, J Whipps, J Rideout, A Evans, S Bentley, M Swabey, H Matthews, N Stevens, R Chivers, T Dominey, K Triscott, and C Carroll

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Redesigning walking brochures using behaviour change theory: implications for walking intentions in natural environments, Lewis R. Elliott, Mathew P. White, Lora E. Fleming, Charles Abraham, and Adrian H. Taylor

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The effect of a dementia awareness class on changing dementia attitudes in adolescents, Nicolas Farina, Laura J. Hughes, Ellen Jones, Sahdia Parveen, Alys W. Griffiths, Kathleen Galvin, and Sube Banerjee

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Disease severity accounts for minimal variance of quality of life in people with dementia and their carers: analyses of cross-sectional data from the MODEM study, N Farina, Derek King, C Burgon, S Berwald, E Bustard, Y Feeney, R Habibi, A Comas-Herrera, Martin Knapp, and S Banerjee

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'You're just a locum': professional identity and temporary workers in the medical profession, Jane Ferguson, Abigail Tazzyman, Kieran Walshe, Marie Bryce, Alan Boyd, Julian Archer, Tristan Price, and John Tredinnick-Rowe

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Constitutive activation of the EGFR–STAT1 axis increases proliferation of meningioma tumor cells, Sara Ferluga, Daniele Baiz, David A. Hilton, Claire L. Adams, Emanuela Ercolano, Jemma Dunn, Kayleigh Bassiri, Kathreena M. Kurian, and Clemens O. Hanemann

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Management of hypoxaemia in the critically ill patient, Luke Flower and Daniel Martin

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Asking about self-harm and suicide in primary care: Moral and practical dimensions, Joseph Ford, Felicity Thomas, Richard Byng, and Rose McCabe

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Use of the Patient Health Questionnaire (PHQ-9) in Practice: Interactions between patients and physicians, Joseph Ford, Felicity Thomas, Richard Byng, and Rose McCabe

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Not so simple: the challenge of developing a non-motor symptoms app (NMS Assist) for people with Parkinson's (PwP), T Gorst, T Dominey, J Whipps, S Whipps, J Cooke, S Mullin, I Maramba, E Edwards, and C Carroll

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Integrating the voluntary sector in personalised care: mixed methods study of the outcomes from wellbeing co-ordination for adults with complex needs, Felix Gradinger, Julian Elston, Sheena Asthana, Chloe Myers, Sue Wroe, and Richard Byng

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Selective Overexpression of EAAT3 in Midbrain Dopamine Neurons Leads to Increased OCD-like Behaviors., N Greene, M Chohan, J Kopelman, E Kramer, S Ahmari, and J Veenstra-VanderWeele

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Engaging Young People During the COVID-19 Pandemic, F Green, T Hobbs, N Axford, D Ellis, J Mannes, M Murphy, R Lily, L Burns, S Rybczynska-Bunt, T Thompson, and J Tredinnick-Rowe

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Sex, gender and gender identity: a re-evaluation of the evidence, Lucy Griffin, Katie Clyde, Richard Byng, and Susan Bewley

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Letter on “Protection by exclusion? The (lack of) inclusion of adults who lack capacity to consent to research in clinical trials in the UK”, Sarah Griffiths, Lorna Manger, Rebecca Chapman, Lauren Weston, Ian Sherriff, Cath Quinn, Paul Clarkson, Caroline Sutcliffe, Karen Davies, and Richard Byng

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Hyperhidrosis Disease Severity Measure-Axillary (HDSM-Ax): Evaluation of Measurement Performance, Jeremy Hobart

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Cognition and its relation to brain health in patients with MS: Response to letter, Jeremy Hobart and Gavin Giovannoni

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Trial of Dexamethasone for Chronic Subdural Hematoma, P. J. Hutchinson, E. Edlmann, D. Bulters, A. Zolnourian, P. Holton, N. Suttner, K. Agyemang, S. Thomson, I. A. Anderson, Y. Z. Al-Tamimi, D. Henderson, P. C. Whitfield, M. Gherle, P. M. Brennan, A. Allison, E. P. Thelin, S. Tarantino, B. Pantaleo, K. Caldwell, C. Davis-Wilkie, H. Mee, E. A. Warburton, G. Barton, A. Chari, H. J. Marcus, A. T. King, A. Belli, P. K. Myint, I. Wilkinson, T. Santarius, C. Turner, S. Bond, and A. G. Kolias

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Protocol for the cultural adaptation of pulmonary rehabilitation and subsequent testing in a randomised controlled feasibility trial for adults with chronic obstructive pulmonary disease in Sri Lanka, AR Jayamaha, CH Perera, MW Orme, AV Jones, UKDC Wijayasiri, TD Amarasekara, RS Karunatillake, A Fernando, ALP Seneviratne, A Barton, R Jones, ZK Yusuf, RB Miah, D Malcolm, JA Matheson, RC Free, A Manise, MC Steiner, SW Wimalasekera, and SJ Singh

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Impact of direct‐acting antiviral agents on liver function in patients with chronic hepatitis C virus infection, Philip J. Johnson, Sarah Berhane, Alex J. Walker, FH Gordon, SD Ryder, S McPherson, A Sreedharan, AA Ustianowski, K Agarwal, D Mutimer, Takeshi Kumada, Hidenori Toyoda, William L. Irving, K Agarwal, M. Aldersley, A. Ala, R. Aspinall, E. Barnes, A. Brown, L. Corless, M. Cramp, D. Forton, G. Foster, M. Foxton, W. Gelson, D. Gorard, F Gordon, S. Khakoo, A. Lawson, S McPherson, S. Moreea, D Mutimer, M. Prince, P. Richardson, W. Rosenberg, S Ryder, A Sreedharan, B. Stone, A Ustianowski, S. Verma, and M. Wiselka

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Speech Therapy in the Treatment of Globus Pharyngeus: Development of a Mobile Application to Improve Patient Access, Hisham Khalil, D Grech-Marguerat, Marios Stavrakas, Abdulaziz Abushaala, Robert Hart, and Arunangsu Chatterjee