The H50Q Mutation Induces a 10-fold Decrease in the Solubility of α-Synuclein

Authors

John Christodoulou, University College London
Riccardo Porcari, University College London
Christos Proukakis, University College London
Christopher A. Waudby, University College London
Benedetta Bolognesi, Pompeu Fabra University
P. Patrizia Mangione, University College London
Jack F.S. Paton, University College London
Stephen Mullin, Peninsula Medical School
Lisa D. Cabrita, University College London
Amanda Penco, University of Genoa
Annalisa Relini, University of Genoa
Guglielmo Verona, University College London
Michele Vendruscolo, University of Cambridge
Monica Stoppini, University of Pavia
Gian Gaetano Tartaglia, Pompeu Fabra University
Carlo Camilloni, University of Cambridge
Anthony H.V. Schapira, University College London
Vittorio Bellotti, University College London

ORCID

• Stephen Mullin: 0000-0002-1936-394X

DOI Link

10.1074/jbc.m114.610527

DOI

10.1074/jbc.m114.610527

Publication Date

2015-01-01

Publication Title

Journal of Biological Chemistry

Volume

290

Issue

4

ISSN

0021-9258

First Page

2395

Last Page

2404

Recommended Citation

Christodoulou, J., Porcari, R., Proukakis, C., Waudby, C., Bolognesi, B., Mangione, P., Paton, J., Mullin, S., Cabrita, L., Penco, A., Relini, A., Verona, G., Vendruscolo, M., Stoppini, M., Tartaglia, G., Camilloni, C., Schapira, A., & Bellotti, V. (2015) 'The H50Q Mutation Induces a 10-fold Decrease in the Solubility of α-Synuclein', Journal of Biological Chemistry, 290(4), pp. 2395-2404. Available at: 10.1074/jbc.m114.610527