Browse research from the Peninsula Medical School.

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Submissions from 2019

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Effects and acceptability of implementing improved cookstoves and heaters to reduce household air pollution: a FRESH AIR study, F van Gemert, C de Jong, B Kirenga, P Musinguzi, and et al

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Can medicines development improve outcomes in asthma and chronic obstructive pulmonary disease management by driving effectiveness?, R Jones, D Leather, L Yates, H Svedsater, L Jacques, S Collier, and D Powell

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Association of smoking and cardiometabolic parameters with albuminuria in people with type 2 diabetes mellitus: a systematic review and meta-analysis, Debasish Kar, Clare Gillies, Mintu Nath, Kamlesh Khunti, Melanie J. Davies, and Samuel Seidu

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Multisystem impairment in South African adolescents with Perinatally acquired HIV on antiretroviral therapy ( ART ), LJ Frigati, K Brown, S Mahtab, L Githinji, and et al

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Motivational interviewing for smoking cessation, Nicola Lindson, Tom P. Thompson, Anne Ferrey, Jeffrey D. Lambert, and Paul Aveyard

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Impact of Quantitative Assessment of Parkinson’s Disease-Associated Symptoms Using Wearable Technology on Treatment Decisions, Camille Carroll, Christopher Kobylecki, Monty Silverdale, and Chris Thomas

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Continuous Free Cortisol Profiles – Circadian Rhythms in Healthy Men, R Bhake, V Kluckner, H Stassen, GM Russell, and et al

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Evaluating the recruitment process into UK anaesthesia core training: a national data linkage study of doctors’ performance at selection and subsequent postgraduate training, Paul A. Tiffin, Margaret Aslet, Lewis W. Paton, and Thomas Gale

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Dual-action CXCR4-targeting liposomes in leukemia: function blocking and drug delivery, C McCallion, AD Peters, A Booth, K Rees-Unwin, J Adams, R Rahi, A Pluen, CV Hutchinson, SJ Webb, and J Burthem

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Longitudinal evaluation of a countywide alternative to the Quality and Outcomes Framework in UK General Practice aimed at improving Person Centred Coordinated Care, James Close, Ben Fosh, Hannah Wheat, Jane Horrell, William Lee, Richard Byng, Michael Bainbridge, Richard Blackwell, Louise Witts, Louise Hall, and Helen Lloyd

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Age and Proficiency in the Bilingual Brain Revisited: Activation Patterns Across Different L2-Learner Types, Tomasina M. Oh, Steven Graham, Philina Ng, Ing Berne Yeh, Bernard P.L. Chan, and Andrew M. Edwards

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A qualitative research synthesis exploring professional touch in healthcare practice using the threshold concept framework, Andy Wearn, Lynn Clouder, Sarah Barradell, and Hilary Neve

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Improving the Early Learning of Children Growing Up in Poverty: A Rapid Review of the Evidence, N Axford and B Albers

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Is collecting patient feedback 'a futile exercise' in the context of recertification?, Rebecca Baines, Daniel Zahra, Marie Bryce, de Bere S Regan, Martin Roberts, and Julian Archer

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The need for novel strategies to address postoperative pain associated with cardiac surgery: A commentary and introduction to “SMArTVIEW”, C Ouellette, S Henry, A Turner, W Clyne, and et al

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The Patient Safety Collaborative Evaluation Study (The PiSCES Study), W Sheaff, R Bethune, N Doran, S Ball, A Medina-Lara, I Lang, M Fornasiero, J McGregor-Harper, and M Harris

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Local radio to promote mental health awareness: A public health initiative, Rohit Shankar, Karen A. Cocksedge, Joshana Guliani, William Henley, Tamsyn Anderson, Sara Roberts, Laurence Reed, Daphne Skinnard, Sarah Fisher, Beth Chapman, Joanna Willcox, Ellen Wilkinson, and Richard Laugharne

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Repositioning the Boundaries between Public and Private Healthcare Providers in the English NHS, Rod Sheaff, Joyce Halliday, Mark Exworthy, Alex Gibson, Pauline W. Allen, Jonathan Clark, Sheena Asthana, and Russell Mannion

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The relationships between symptoms, disability, perceived health and quality of life in amyotrophic lateral sclerosis/motor neuron disease, Carolyn Anne Young, John Ealing, Christopher McDermott, Tim Williams, Ammar Al-Chalabi, Tahir Majeed, Georgina Burke, Ashwin Pinto, David Dick, Kevin Talbot, Timothy Harrower, Jannette Walsh, Siddharthan Chandran, C. Oliver Hanemann, Roger Mills, and Alan Tennant

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Clathrin-containing adhesion complexes, John G. Lock, Francesco Baschieri, Matthew C. Jones, JD Humphries, Guillaume Montagnac, Staffan Strömblad, and MJ Humphries

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Effect of Constant versus Variable Small-Group Facilitators on Student Basic Science Knowledge in an Enquiry-Based Dental Curriculum, Svetislav Zaric, Daniel Zahra, Jon Bennett, Louise Belfield, Kamran Ali, Clare Mcilwaine, Malcolm Bruce, Gill Jones, Zoe L. Brookes, and Catherine Coelho

Evolution of prodromal parkinsonian features in a cohort of GBA mutation-positive individuals: a 6-year longitudinal study, Anthony H.V. Schapira, Micol Avenali, Marco Toffoli, Stephen Mullin, Alisdair McNeil, Derralynn A. Hughes, A. Mehta, and Fabio Blandini

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The Central Autonomic Network and Regulation of Bladder Function, Alexander L. Green and Holly Ann Roy

Head first – Review of epilepsy head injury risk and protection, Rohit Shankar, Caryn Jory, Katy Oak, Catriona Organ, and Brendan Mclean

Additional behavioural support as an adjunct to pharmacotherapy for smoking cessation, Jamie Hartmann-Boyce, Bosun Hong, Jonathan Livingstone-Banks, Hannah Wheat, and Thomas R. Fanshawe

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STRIPAK Members Orchestrate Hippo and Insulin Receptor Signaling to Promote Neural Stem Cell Reactivation, Claudia S. Barros, Jon Gil-Ranedo, Eleanor Gonzaga, Karolina J. Jaworek, Christian Berger, and Torsten Bossing

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National prospective observational study of inpatient management of adults with epistaxis – a National Trainee Research Collaborative delivered investigation, N Mehta, K Stevens, ME Smith, RJ Williams, and et al

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Outcomes following surgery in subgroups of comatose and very elderly patients with chronic subdural hematoma, Paul M. Brennan, on behalf of the British Neurosurgical Trainee Research Collaborative (BNTRC), Edward Christopher, Michael T.C. Poon, Laurence J. Glancz, Peter J. Hutchinson, Angelos G. Kolias, F. T. Afshari, A. I. Ahmed, S. Alli, R. Al-Mahfoudh, J. Bal, A. Belli, A. Borg, D. Bulters, N. Carleton-Bland, A. Chari, D. Coope, I. C. Coulter, C. J. Cowie, G. Critchley, S. Dambatta, D. D’Aquino, B. Dhamija, G. Dobson, M. D. Fam, W. P. Gray, B. A. Gregson, P. J. Grover, and J. Halliday

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Oral bovine colostrum supplementation does not increase circulating insulin-like growth factor-1 concentration in healthy adults: results from short- and long-term administration studies, G Davison, AW Jones, T Marchbank, and RJ Playford

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‘Left with a title but nothing else’: The challenges of embedding professional recognition schemes for teachers within higher education institutions, Lucy Spowart, Jennie Winter, Rebecca Turner, Penny Burden, Kathryn Ann Botham, Reema Muneer, der Sluis H van, and Isabel Huet

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A phase III trial of tirasemtiv as a potential treatment for amyotrophic lateral sclerosis, Jeremy M. Shefner, on behalf of the VITALITY-ALS STUDY GROUP, Merit E. Cudkowicz, Orla Hardiman, Bettina M. Cockroft, Jacqueline H. Lee, Fady I. Malik, Lisa Meng, Stacy A. Rudnicki, Andrew A. Wolff, Jinsy A. Andrews, and Oliver Hanemann

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Sociodemographic and educational characteristics of doctors applying for psychiatry training in the UK: secondary analysis of data from the UK Medical Education Database project, Thomas C.E. Gale, Paul J. Lambe, Tristan Price, and Martin J. Roberts

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Crossing boundaries: Global reorientation following transfer from the inside to the outside of an arena, Mark Haselgrove, Matthew G. Buckley, Luke J. Holden, Stuart G. Spicer, and Alastair D. Smith

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Utilization of volumetric magnetic resonance imaging for baseline and surveillance imaging in Neuro-oncology, Samantha J. Mills, Mark R. Radon, Richard D. Baird, C. Oliver Hanemann, Debbie Keatley, Joanne Lewis, Jonathan Pollock, Paul Sanghera, Thomas Santarius, Gillian Whitfield, Rasheed Zakaria, and D. J Michael

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Identifying and managing concerns about GPs in England: an interview study and case-series analysis, Abigail Tazzyman, Marie Bryce, Alan Boyd, and Kieran Walshe

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Characterization of the urinary metabolic profile of cholangiocarcinoma in a United Kingdom population, M Alsaleh, T Barbera, H Reeves, M Cramp, S Ryder, H Gabra, K Nash, Y-L Shen, E Holmes, R Williams, and S Taylor-Robinson

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Reflections on the Researcher-in-Residence model co-producing knowledge for action in an Integrated Care Organisation: a mixed methods case study using an impact survey and field notes, Felix Gradinger, Julian Elston, Sheena Asthana, Susan Martin, and Richard Byng

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G240 Prevalence and patterns of mental health-related paediatric hospital admissions, RS Bates, TV Newlove-Delgado, K Husk, and V Berry

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Ibrutinib for the treatment of relapsed/refractory mantle cell lymphoma: extended 3.5-year follow up from a pooled analysis, S Rule, M Dreyling, A Goy, G Hess, and et al

Mitogen-Activated Protein Kinase Cross-Talk Interaction Modulates the Production of Melanins in Aspergillus fumigatus, AO Manfiolli, FS Siqueira, Reis TF dos, Dijck P Van, S Schrevens, S Hoefgen, M Föge, M Straßburger, Leandro Jose De Assis, T Heinekamp, MC Rocha, S Janevska, AA Brakhage, I Malavazi, GH Goldman, and V Valiante

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Capital punishment, my sixth great grandfather, and me-an essay by J Robert Sneyd, J. Robert Sneyd

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Comparing psychiatric care experiences shared online with validated questionnaires; do they include the same content?, Rebecca Baines, John Donovan, de Bere S Regan, Julian Archer, and Ray Jones

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Sustainability of equality: a paradox for democracy, S Burr, YL Leung, and KS McManus

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Self-Management Support Intervention for Parents of Children with Developmental Disorders: The Role of Gratitude and Hope, F Martin, W Clyne, G Pearce, and A Turner

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WFDC2 contributes to epithelial-mesenchymal transition (EMT) by activating AKT signaling pathway and regulating MMP-2 expression, Y Chen, L Huang, S Wang, J-L Li, and et al

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Correction: Dexamethasone for adult patients with a symptomatic chronic subdural haematoma (Dex-CSDH) trial: Study protocol for a randomised controlled trial (Trials (2018) 19:670 DOI: 10.1186/s13063-018-3050-4), Angelos G. Kolias, Ellie Edlmann, Eric P. Thelin, Diederik Bulters, Patrick Holton, Nigel Suttner, Kevin Owusu-Agyemang, Yahia Z. Al-Tamimi, Daniel Gatt, Simon Thomson, Ian A. Anderson, Oliver Richards, Peter Whitfield, Monica Gherle, Karen Caldwell, Carol Davis-Wilkie, Silvia Tarantino, Garry Barton, Hani J. Marcus, Aswin Chari, Paul Brennan, Antonio Belli, Simon Bond, Carole Turner, Lynne Whitehead, Ian Wilkinson, and Peter J. Hutchinson

Acute myeloid leukaemia: an unusual cause of biliary strictures., David Sheridan, Adele Beck, Hannah Hunter, and Simon Jackson

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Prospective comparative study of the effects of lidocaine on urodynamic and sensory parameters in bladder pain syndrome, I Offiah, E Dilloughery, SB McMahon, and BA O’Reilly

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Causes of death among homeless people: a population-based cross-sectional study of linked hospitalisation and mortality data in England., Robert W. Aldridge, Dee Menezes, Dan Lewer, Michelle Cornes, Hannah Evans, Ruth M. Blackburn, Richard Byng, Michael Clark, Spiros Denaxas, James Fuller, Nigel Hewett, Alan Kilmister, Serena Luchenski, Jill Manthorpe, Martin McKee, Joanne Neale, Alistair Story, Michela Tinelli, Martin Whiteford, Fatima Wurie, and Andrew Hayward

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Comprehensive analysis of aspergillus nidulans PKA phosphorylome identifies a novel mode of CreA regulation, Mark R. Martena, Liliane F.C. Ribeiro, Cynthia Chelius, Karthik R. Boppidi, Nisha S. Naik, Simin Hossain, Jessica J.J. Ramsey, Jyothi Kumar, Lucas F. Ribeiro, Marc Ostermeier, Bao Tran, Young Ah Goo, Leandro J. Assis, Mevlut Ulas, Ozgur Bayram, Gustavo H. Goldman, Stephen Lincoln, Ranjan Srivastava, and Steven D. Harris

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Quality of stepped-wedge trial reporting can be reliably assessed using an updated CONSORT: crowd-sourcing systematic review, K Hemming, K Carroll, J Thompson, and The SW-CRT Review Group

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Gene expression meta-analysis of Parkinson's disease and its relationship with Alzheimer's disease, Xinzhong Li, Jack Kelly, Rana Moyeed, Camille Carroll, and Diego Albani

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Valproate MHRA Guidance: Limitations and Opportunities, Rohit Shankar, Lance Watkins, Hannah Cock, Heather Angus-Leppan, Kim Morley, and Mike Wilcock

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Novel use of tranexamic acid to reduce the need for Nasal Packing in Epistaxis (NoPac) randomised controlled trial: research protocol., A Reuben, A Appelboam, A Barton, PJ Vickery, and et al

Intellectual disability and epilepsy, Rohit Shankar, Lance Watkins, and Stephen Brown

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A variant in the MICA gene is associated with liver fibrosis progression in chronic hepatitis C through TGF-β1 dependent mechanisms., Jacob George, Rasha El Sharkawy, Ali Bayoumi, Mayada Metwally, Alessandra Mangia, Thomas Berg, Manuel Romero-Gomez, Maria Lorena Abate, William L. Irving, David Sheridan, Gregory J. Dore, Ulrich Spengler, Pietro Lampertico, Elisabetta Bugianesi, Martin Weltman, Lindsay Mollison, Wendy Cheng, Stephen Riordan, Rosanna Santoro, Rocío Gallego-Durán, Janett Fischer, Jacob Nattermann, R D'Ambrosio, Duncan McLeod, Elizabeth Powell, Olivier latchoumanin, Khaled Thabet, Mustafa A.M. Najim, Mark W. Douglas, Christopher Liddle, Jacob George, Mohammed Eslam, and Liver Disease Genetics Consortium (ILDGC) International

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Phase 0 trial investigating the intra-tumoural concentration and activity of Sorafenib in Neurofibromatosis type 2, C. Oliver Hanemann, Sylwia Ammoun, D. Gareth Evans, David A. Hilton, Adam Streeter, and Christopher Hayward

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RN181 is a tumour suppressor in gastric cancer by regulation of the ERK/MAPK–cyclin D1/CDK4 pathway, S Wang, X Wang, Y Gao, Y Peng, and et al

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Corrigendum to "Coital Incontinence: What Can We Learn From Urodynamic Assessment?" [Urology 85 (2015) 1034-1038]., C Madhu, H Hashim, D Enki, M Yassin, and M Drake

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Reflective practice for patient benefit: an analysis of doctors' appraisal portfolios in Scotland, Judy Wakeling, Sarah Holmes, Alan Boyd, John Tredinnick-Rowe, Niall Cameron, Martin Marshall, Marie Bryce, and Julian Archer

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Accuracy of FibroScan Controlled Attenuation Parameter and Liver Stiffness Measurement in Assessing Steatosis and Fibrosis in Patients With Non-alcoholic Fatty Liver Disease., Philip N. Newsome, Peter J. Eddowes, Magali Sasso, Michael Allison, Emmanouil Tsochatzis, Quentin M. Anstee, David Sheridan, Indra N. Guha, Jeremy F. Cobbold, Jonathan J. Deeks, Valérie Paradis, and Pierre Bedossa

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Protocol for a feasibility randomised controlled trial of targeted oxygen therapy in mechanically ventilated critically ill patients, Daniel S. Martin, Chris Brew-Graves, Neil McCartan, Gavin Jell, Ingrid Potyka, Jia Stevens, Norman R. Williams, Margaret McNeil, BR O’Driscoll, Monty Mythen, and Michael P.W. Grocott

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Improving communication for learning with students: expectations, feedback and feedforward, T Ley, J Kisielewska, T Collett, and SA Burr

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Molecular and translational advances in meningiomas, Kenneth Aldape, Suganth Suppiah, Farshad Nassiri, Wenya Linda Bi, Ian F. Dunn, Clemens Oliver Hanemann, Craig M. Horbinski, Rintaro Hashizume, CD James, Christian Mawrin, Houtan Noushmehr, Arie Perry, Felix Sahm, Andrew Sloan, Deimling A Von, Patrick Y. Wen, Gelareh Zadeh, Karolyn Au, Jill Barnhartz-Sloan, Priscilla K. Brastianos, Nicholas Butowski, Carlos Carlotti, Michael D. Cusimano, Francesco Dimeco, Katharine Drummond, Evanthia Galanis, Caterina Giannini, Roland Goldbrunner, Brent Griffith, Christel Herold-Mende, Roland Goldbrunner, Brent Griffith, Rintaro Hashizume, Clemens Oliver Hanemann, Christel Herold-Mende, Craig M. Horbinski, Raymond Y. Huang, D James, Michael D. Jenkinson, Christine Jungk, and Timothy J. Kaufman

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Reforming regulatory relationships: The impact of medical revalidation on doctors, employers, and the General Medical Council in the United Kingdom, Abigail Tazzyman, Marie Bryce, Jane Ferguson, Kieran Walshe, Alan Boyd, Tristan Price, and John Tredinnick-Rowe

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Refining a model of collaborative care for people with a diagnosis of bipolar, schizophrenia or other psychoses in England: a qualitative formative evaluation, Elina Baker, Ruth Gwernan-Jones, Nicky Britten, Maria Cox, Catherine McCabe, Ameeta Retzer, Laura Gill, Humera Plappert, Siobhan Reilly, Vanessa Pinfold, Linda Gask, Richard Byng, and Max Birchwood

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11.39 Association of british neurologists sustainability special interest group (ABN sustainability SIG): formation, objectives and invitation, A Cheesman, D Blackburn, C Carroll, A Cohen, J Coebergh, D Sokhi, SH Wong, and J Woolmore

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137 Usability testing of a non-motor symptom app in PD, T Dominey, S Mullin, E Edwards, J Whipps, S Whipps, and C Carroll

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163 Development of clinical and patient-reported quality metrics for multiple sclerosis: a UK pilot study report, G Giovannoni, S White, N Mistry, S Calhoun, C Young, M Coutts, M Roberts, P Anderson, R Bernstein, and J Hobart

A Retrospective Cohort Study of the Survival Rate of 88 Zygomatic Implants Placed Over an 18-year Period, Harjot Bansal, Harpal Chana, Graham Smith, and Daniel Zahra

A serious game to train patient safety outside the classroom: a pilot study of acceptability, Victoria K. Field, Tom Gale, Cor Kalkman, Pamela Kato, and Catherine T. Ward

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Aspergillus fumigatushigh osmolarity glycerol mitogen activated protein kinases saka and mpkc physically interact during osmotic and cell wall stresses, Gustavo H. Goldman, Adriana Oliveira Manfiolli, Eliciane Cevolani Mattos, Leandro José De Assis, Lilian Pereira Silva, Mevlüt Ulas, Neil Andrew Brown, Rafael Silva-Rocha, and Özgür Bayram

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Assessment of Clinically Meaningful Improvements in Self-Reported Walking Ability in Participants with Multiple Sclerosis: Results from the Randomized, Double-blind, Phase III ENHANCE Trial of Prolonged-release Fampridine, Jeremy Hobart, Tjalf Ziemssen, Peter Feys, Michael Linnebank, Andrew D. Goodman, Rachel Farrell, Raymond Hupperts, Andrew R. Blight, Veronica Englishby, Manjit McNeill, Ih Chang, and Jacob Elkins

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Best practice guidelines for training professional carers in the administration of buccal (oromucosal) midazolam for the treatment of prolonged and/or clusters of epileptic seizures in the community, Rohit Shankar

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Bile acid metabolism is altered in those with insulin resistance after gestational diabetes mellitus, Negar Maghsoodi, Nicholas Shaw, Gemma F. Cross, Jamshid Alaghband-Zadeh, Anthony S. Wierzbicki, Jonathan Pinkney, Ann Millward, and Royce P. Vincent

Cardiovascular autonomic responses in patients with Parkinson disease to pedunculopontine deep brain stimulation, Alexander L. Green, Jonathan A. Hyam, Holly A. Roy, Yongzhi Huang, Sean Martin, Shouyan Wang, Jodi Rippey, Terry J. Coyne, Ian Stewart, Graham Kerr, Peter Silburn, David J. Paterson, and Tipu Z. Aziz

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Computational instantaneous wave‐free ratio (IFR) for patient‐specific coronary artery stenoses using 1D network models, Perumal Nithiarasu, Jason M. Carson, Carl Roobottom, and Robin Alcock

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Correction to: Dexamethasone for adult patients with a symptomatic chronic subdural haematoma (Dex-CSDH) trial: study protocol for a randomised controlled trial, Angelos G. Kolias, Ellie Edlmann, Eric P. Thelin, Diederik Bulters, Patrick Holton, Nigel Suttner, Kevin Owusu-Agyemang, Yahia Z. Al-Tamimi, Daniel Gatt, Simon Thomson, Ian A. Anderson, Oliver Richards, Peter Whitfield, Monica Gherle, Karen Caldwell, Carol Davis-Wilkie, Silvia Tarantino, Garry Barton, Hani J. Marcus, Aswin Chari, Paul Brennan, Antonio Belli, Simon Bond, Carole Turner, Lynne Whitehead, Ian Wilkinson, and Peter J. Hutchinson

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Dex-CSDH randomised, placebo-controlled trial of dexamethasone for chronic subdural haematoma: report of the internal pilot phase, Ellie Edlmann, Eric P. Thelin, Karen Caldwell, Carole Turner, Peter Whitfield, Diederik Bulters, Patrick Holton, Nigel Suttner, Kevin Owusu-Agyemang, Yahia Z. Al-Tamimi, Daniel Gatt, Simon Thomson, Ian A. Anderson, Oliver Richards, Monica Gherle, Emma Toman, Dipankar Nandi, Phillip Kane, Beatrice Pantaleo, Carol Davis-Wilkie, Silvia Tarantino, Garry Barton, Hani J. Marcus, Aswin Chari, Antonio Belli, Simon Bond, Rafael Gafoor, Sarah Dawson, Lynne Whitehead, Paul Brennan, Ian Wilkinson, Angelos G. Kolias, and Peter J.A. Hutchinson

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DNA methylation profiling to predict recurrence risk in meningioma: development and validation of a nomogram to optimize clinical management, Kenneth D. Aldape, F Nassiri, Y Mamatjan, S Suppiah, Jetan H. Badhiwala, Sheila Mansouri, Shirin Karimi, Olli Saarela, L Poisson, Irina Gepfner-Tuma, Jens Schittenhelm, Ho Keung Ng, H Noushmehr, Patrick Harter, Peter Baumgarten, Michael Weller, Matthias Preusser, C Herold-Mende, M Tatagiba, G Tabatabai, F Sahm, Deimling A von, Karolyn Au, Jill Barnhartz-Sloan, Wenya Linda Bi, Priscilla K. Brastianos, Nicholas Butowski, Carlos Carlotti, Michael D. Cusimano, Francesco Dimeco, Katharine Drummond, Ian F. Dunn, Evanthia Galanis, Caterina Giannini, Roland Goldbrunner, Brent Griffith, Rintaro Hashizume, C. Oliver Hanemann, C Herold-Mende, Craig Horbinski, and Raymond Y. Huang

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Endo-β-1,3-glucanase (GH16 family) from trichoderma harzianum participates in cell wall biogenesis but is not essential for antagonism against plant pathogens, Roberto Nascimento Silva, Marcela Suriani Ribeiro, Renato Graciano de Paula, Aline Raquel Voltan, Raphaela Georg de Castro, Cláudia Batista Carraro, Leandro José de Assis, Andrei Stecca Steindorff, Gustavo Henrique Goldman, Cirano José Ulhoa, and Valdirene Neves Monteiro

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Evaluation of a countywide alternative to QOF, aimed at improving person-centred coordinated care, J Close, B Fosh, R Byng, R Blackwell, L Witts, L Hall, and H Lloyd

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Evaluation of the detection of GBA missense mutations and other variants using the Oxford Nanopore MinION, Christos Proukakis, M Leija‐Salazar, Fritz J. Sedlazeck, Marco Toffoli, Stephen Mullin, Katya Mokretar, Maria Athanasopoulou, Aimee Donald, Reena Sharma, Derralynn Hughes, and Anthony H.V. Schapira

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Evaluation of the impact of the NICE head injury guidelines on inpatient mortality from traumatic brain injury: an interrupted time series analysis, Carl Marincowitz, Fiona Lecky, Victoria Allgar, and Trevor Sheldon

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Evolution and clustering of prodromal parkinsonian features in GBA1 carriers, Anthony H.V. Schapira, Stephen Mullin, Michelle Beavan, Jonathan Bestwick, Alisdair McNeill, Christos Proukakis, Timothy Cox, Derralynn Hughes, Atul Mehta, and Henrik Zetterberg

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Exploring how patients respond to GP recommendations for mental health treatment: an analysis of communication in primary care consultations, Joseph Ford, Felicity Thomas, Richard Byng, and Rose McCabe

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From mental disorder to shared understanding: a non-categorical approach to support individuals with distress in primary care, Richard Byng, Nora Groos, and Christopher Dowrick

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Gender incongruence in children, adolescents and adults, Susan Bewley, Damian Clifford, Margaret McCartney, and Richard Byng

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Gender incongruence in children, adolescents, and adults: response to Dr White, M McCartney, S Bewley, D Clifford, and R Byng

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Going to extremes: the Goldilocks/Lagom principle and data distribution, Henry J. Leese, Thozhukat Sathyapalan, Victoria Allgar, Daniel R. Brison, and Roger Sturmey

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Hemizygous UBA5 missense mutation unmasks recessive disorder in a patient with infantile-onset encephalopathy, acquired microcephaly, small cerebellum, movement disorder and severe neurodevelopmental delay, Karen J. Low, J. Baptista, M. Babiker, R. Caswell, C. King, S. Ellard, and I. Scurr

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How data science can advance mental health research, TC Russ, E Woelbert, KAS Davis, JD Hafferty, and et al

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How Group-Based Interventions Can Improve Services for People with Severe Obesity, Mark Tarrant, Dawn Swancutt, and Jonathan Pinkney

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Impact of “enhanced” intermediate care located in a health & wellbeing hub at the integrated care organisation (ico) in torbay and south devon, uk, J Elston, F Gradinger, S Asthana, M Fox, L Dawson, D Butler, and R Byng

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Implementation and impact of co-locating the voluntary sector with a multidisciplinary, cross-sector community hub at the Integrated Care Organisation (ICO) in Torbay and South Devon, UK, F Gradinger, J Elston, S Asthana, C Lilley-Woolnough, C Myers, M Fox, D Butler, and R Byng

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Insulin Resistance during normal child growth and development is associated with a distinct blood metabolic phenotype (Earlybird 72), Joanne Hosking, Jonathan Pinkney, Alison Jeffery, Ornella Cominetti, Silva L Da, Sebastiano Collino, Martin Kussmann, Jorg Hager, and Francois Pierre Martin

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It's more than just a referral: Development of an evidence-informed exercise and depression toolkit, Krista Glowacki, Kelly Arbour-Nicitopoulos, Meghan Burrows, Leslie Chesick, Lyn Heinemann, Sarah Irving, Raymond W. Lam, Soultana Macridis, Erin Michalak, Aidan Scott, Adrian Taylor, and Guy Faulkner

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Measuring upper limb function in multiple sclerosis clinical trials: definition, conceptualisation and measurement, S Parker, L Burke, and J Hobart

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Mitochondria in neurodegenerative diseases, Fang Lin and Shou Qing Luo

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Mitochondrial integrity in neurodegeneration, Oleg Anichtchik, Katrina Cowan, and Shouqing Luo