Browse research from the Peninsula Medical School.

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Submissions from 2018

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Trial of intraoperative cell salvage versus transfusion in ovarian cancer (TIC TOC): protocol for a randomised controlled feasibility study, K Galaal, A Lopes, C Pritchard, A Barton, and et al

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Redesigning gender identity services: an opportunity to generate evidence, Richard Byng, Susan Bewley, Damian Clifford, and Margaret McCartney

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Remediating doctors' performance to restore patient safety: a realist review protocol., Tristan Price, Nicola Brennan, Jennifer Cleland, Linda Prescott-Clements, Amanda Wanner, Lyndsey Withers, Geoff Wong, and Julian Archer

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The impact of emergency department patient-controlled analgesia (PCA) on the incidence of chronic pain following trauma and non-traumatic abdominal pain., M Rockett, S Creanor, R Squire, A Barton, and et al

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Analysis of question text properties for equality monitoring., Daniel Zahra and Steven A. Burr

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SHERPA: a new model for clinical decision making in patients with multimorbidity, Edmund Jack, Neal Maskrey, and Richard Byng

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Learning to become a primary care professional: insights from threshold concept theory., Hilary Neve

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Updated results from the phase 3 HELIOS study of ibrutinib, bendamustine and rituximab in 1 relapsed chronic lymphocytic leukemia/small lymphocytic lymphoma, SAJ Rule

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Building programme theory to develop more adaptable and scalable complex interventions: Realist formative process evaluation prior to full trial, Sarah Louise Brand, Cath Quinn, Mark Pearson, Charlotte Lennox, Christabel Owens, Tim Kirkpatrick, Lynne Callaghan, Alex Stirzaker, Susan Michie, Mike Maguire, Jennifer Shaw, and Richard Byng

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Teaching sociology to undergraduate medical students, K Kendall, T Collett, Iongh A de, S Forrest, and M Kelly

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Prolonged-release fampridine in multiple sclerosis: clinical data and real-world experience – report of an expert meeting, Philipp Albrecht, IK Bjorna, David Brassat, Rachel Farrell, Peter Feys, Jeremy Hobart, Raymond Hupperts, Michael Linnebank, J Magdic, Celia Oreja-Guevara, Carlo Pozzilli, Antonio Vasco Salgado, and Tjalf Ziemssen

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Randomised controlled trial of the Limit of Detection of Troponin and ECG Discharge (LoDED) strategy versus usual care in adult patients with chest pain attending the emergency department: study protocol, E Carlton, S Campbell, J Ingram, R Kandiyali, and et al

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Designing a care pathway for high risk parkinson’s patients, TLY Chloe, T Dominey, E Pearson, F Murphy, and C Carroll

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Evaluating the clinical utility of the parkinson’s kinetigraph (PKG), L Hutchinson, T Dominey, E Pearson, F Murphy, L Bell, and C Carroll

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Exercise for people with Parkinson’s: a practical approach, Bhanu Ramaswamy, Julie Jones, and Camille Carroll

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First comprehensive tool for screening pain in Parkinson's disease: The King's Parkinson's Disease Pain Questionnaire (KPPQ)., P. Martinez-Martin, A. M. Rizos, J. Wetmore, A. Antonini, P. Odin, S. Pal, R. Sophia, C. Carroll, D. Martino, C. Falup-Pecurariu, B. Kessel, T. Andrews, D. Paviour, C. Trenkwalder, K. R. Chaudhuri, and EUROPAR & MDS Non-Motor PD Study Group

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Improving community exercise provision in Parkinson’s, M Palin, J Rideout, C Carroll, and V Evans

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Responding effectively to adult mental health patient feedback in an online environment: A coproduced framework, Rebecca Baines, John Donovan, de Bere S Regan, Julian Archer, and Ray Jones

Sudden unexpected death in epilepsy in children: A focused review of incidence and risk factors, Khalid Hamandi, Anurag Saxena, Lliwen Jones, Rohit Shankar, Brendan McLean, and Craig G.J. Newman

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The feasibility of following up prisoners, with mental health problems, after release: A pilot trial employing an innovative system, for engagement and retention in research, with a harder to engage population., Cath Quinn, Richard Byng, Deborah Shenton, Cordet Smart, S Mitchie, Amy Stewart, Rod Taylor, Mike Maguire, Tirril Harris, and Jenny Shaw

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Validation of Multisource Feedback in Assessing Medical Performance: A Systematic Review, SAG Stevens, J Read, R Baines, A Chatterjee, and J Archer

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Towards commissioning for workplace compassion: a support guide, W Clyne and K Deeny

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Neuromodulation for Pelvic and Urogenital Pain, Holly Roy, Ifeoma Offiah, and Anu Dua

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Public Health and Well-being Innovation in the Natural Environment Sector: Lessons from the UK and Finland, J Tredinnick-Rowe, T Taylor, and A Tuohino

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Multicentred randomised controlled trial of an augmented exercise referral scheme using web-based behavioural support in individuals with metabolic, musculoskeletal and mental health conditions: protocol for the e-coachER trial, Wendy Ingram, Douglas Webb, RS Taylor, Nana Anokye, Lucy Yardley, Kate Jolly, Nanette Mutrie, John L. Campbell, SG Dean, Colin Greaves, Mary Steele, Jeffrey D. Lambert, Chloe McAdam, Ben Jane, Jennie King, Ray B. Jones, Paul Little, Anthony Woolf, Jo Erwin, Nigel Charles, Rohini H. Terry, AH Taylor, and TS Comm

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Diverse Healthcare Providers: Behaviour in response to commissioners, patients and innovations, WR Sheaff, J Halliday, M Exworthy, A Gibson, P Allen, J Clark, S Asthana, and R Mannion

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Chronic respiratory symptoms and lung abnormalities among people with a history of tuberculosis in Uganda: a national survey., Kampen SC van, Rupert Jones, Harriet Kisembo, Rein M.G.J. Houben, Yinghui Wei, Frank R. Mugabe, Elizeus Rutebemberwa, and Bruce Kirenga

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A holistic remediation intervention for struggling undergraduate medical students affords sustained Progress Test performance recovery, CP Gray and N Toms

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An integrated genomic analysis of anaplastic meningioma identifies prognostic molecular signatures., Grace Collord, Patrick Tarpey, Natalja Kurbatova, Inigo Martincorena, Sebastian Moran, Manuel Castro, Tibor Nagy, Graham Bignell, Francesco Maura, MD Young, Jorge Berna, Jose M.C. Tubio, Chris E. McMurran, AMH Young, Mathijs Sanders, Imran Noorani, Stephen J. Price, Colin Watts, Elke Leipnitz, Matthias Kirsch, Gabriele Schackert, Danita Pearson, Abel Devadass, Zvi Ram, V. Peter Collins, Kieren Allinson, Michael D. Jenkinson, Rasheed Zakaria, Khaja Syed, C. Oliver Hanemann, Jemma Dunn, MW McDermott, Ramez W. Kirollos, George S. Vassiliou, Manel Esteller, Sam Behjati, Alvis Brazma, Thomas Santarius, and U McDermott

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Cell adhesion is regulated by CDK1 during the cell cycle, Matthew C. Jones, Janet A. Askari, JD Humphries, and MJ Humphries

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Might children rust? What are the risks of supplemental oxygen in acute illness, Daniel Martin and Mark J. Peters

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Decreasing the risk of sudden unexpected death in epilepsy: structured communication of risk factors for premature mortality in people with epilepsy, R Shankar, W Henley, C Boland, R Laugharne, and et al

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Home visits: A new screening tool for frailty? A retrospective exploratory study, D Attwood, K Stevens, L Jones, L Harris, and F Roberts

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Organisation and delivery of liaison psychiatry services in general hospitals in England: results of a national survey, A Walker, JR Barrett, W Lee, RM West, and et al

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Proton Pump Inhibitor use as a risk factor for Enterobacteriaceal infection: a case-control study, R Cunningham, L Jones, DG Enki, and R Tischhauser

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Sweden shows how the Nordic model could improve women’s wellbeing and create a better society, Harriet Evans, Richard Byng, Lynne Callaghan, and Anna Fisher

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Twelve tips for teaching twelve transferable skills, HR Watson and SA Burr

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A zinc-finger fusion protein refines Gal4-defined neural circuits., Shamprasad Varija Raghu, Farhan Mohammad, Jia Yi Chua, Joanne Shi Woon Lam, Mavis Loberas, Sadhna Sahani, Claudia S. Barros, and Adam Claridge-Chang

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Does pulmonary rehabilitation alter patients’ experiences of living with chronic respiratory disease? A qualitative study., RCM Jones, H Muyinda, B Kirenga, W Katagira, and J Pooler

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The National Health Service (NHS) in 'crisis': the role played by a shift from horizontal to vertical principles of equity., Sheena Asthana and Alex Gibson

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Design and implementation of a tool for conversion of search strategies between PubMed and Ovid MEDLINE, AA Wanner and N Baumann

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Patient-reported outcomes with initiation of fluticasone furoate/vilanterol versus continuing usual care in the asthma Salford Lung Study, H Svedsater, R Jones, N Bosanquet, L Jacques, J Lay-Flurrie, DA Leather, J Vestbo, S Collier, and A Woodcock

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Risk of thromboembolism in patients developing critical illness-associated atrial fibrillation, B Clayton, S Ball, J Read, and S Waddy

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The impact of patient feedback on the medical performance of qualified doctors: a systematic review, Rebecca Baines, Bere SR de, Sebastian Stevens, Jamie Read, Martin Marshall, Mirza Lalani, Marie Bryce, and Julian Archer

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Threshold Concepts, Action Poetry and the Health Professions: An Interview with Ray Land, HA Neve, R Land, and L martindale

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Policing the profession? Regulatory reform, restratification and the emergence of Responsible Officers as a new locus of power in UK medicine, Marie Bryce, Kayleigh Luscombe, Alan Boyd, Abigail Tazzyman, John Tredinnick-Rowe, Kieran Walshe, and Julian Archer

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Association between blood eosinophil count and risk of readmission for patients with asthma: historical cohort study, RCM Jones, M Kerkhof, DB Price, T Tran, den Berge M van, G Brusselle, G Gopalan, J Kocks, A Menzies-Gow, J Nuevo, I Pavord, and S Rastogi

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Perampanel in routine clinical use across Europe: Pooled, multicenter, observational data, Eugen Trinka, Alexandra Rohracher, Georg Zimmermann, Vicente Villanueva, Iñigo Garamendi, Josemir W. Sander, Tim Wehner, Rohit Shankar, Elinor Ben-Menachem, Martin J. Brodie, Max C. Pensel, Giancarlo Di Gennaro, Aude Maurousset, Adam Strzelczyk, Sylvain Rheims, Attila Rácz, Katja Menzler, Vicente Bertol-Alegre, Irene García-Morales, Francisco Javier López-González, Manuel Toledo, and Katherine J. Carpenter

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International research and guidelines on post-tuberculosis chronic lung disorders: a systematic scoping review., Kampen SC van, A Wanner, M Edwards, AD Harries, BJ Kirenga, J Chakaya, and R Jones

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Research skills in medical education, HR Watson and SA Burr

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Engaging "seldom heard" groups in research and intervention development: Offender mental health., Charlie Taylor, Laura Gill, Andy Gibson, Richard Byng, and Cath Quinn

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When another assessment attempt is bad for progress., SA Burr, JM Morrison, and VM Salih

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Getting a balance between generalisation and specialisation in mental health services: A defence of general services, Richard Laugharne, Matthew Thompson, Alind Srivastava, Simon Marlow, and Rohit Shankar

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Web-based intervention using behavioral activation and physical activity for adults with depression (The eMotion study): Pilot randomized controlled trial, Jeffrey D. Lambert, Colin J. Greaves, Paul Farrand, Lisa Price, Anne M. Haase, and Adrian H. Taylor

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Noninvasive options for ‘wearing-off’ in Parkinson's disease: a clinical consensus from a panel of UK Parkinson's disease specialists, CB Carroll, R Fackrell, D Grosset, B Mohamed, P Reddy, M Parry, K Chaudhuri, and T Foltynie

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A British Society for Haematology Good Practice Paper on the Diagnosis and Investigation of Patients with Mantle Cell Lymphoma, P McKay, M Leach, B Jackson, S Robinson, and SAJ Rule

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Guideline for the Management of Mantle Cell Lymphoma, SAJ Rule, P McKay, M Leach, R Jackson, and S Robinson

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Intervention Delivery Fidelity Assessment of a Counseling-Based Intervention for Promoting Smoking Reduction and Increasing Physical Activity, Tom P. Thompson, Jeffrey D. Lambert, Colin J. Greaves, and Adrian H. Taylor

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Machine-learning based identification of undiagnosed dementia in primary care: a feasibility study, Emmanuel A. Jammeh, Camille B. Carroll, SW Pearson, Javier Escudero, Athanasios Anastasiou, Peng Zhao, Todd Chenore, John Zajicek, and Emmanuel Ifeachor

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Postoperative Remote Automated Monitoring: Need for and State of the Science, MH McGillion and PROTECT Network Investigators

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Quality after the QOF? Before dismantling it, we need a redefined measure of ‘quality’, James Close, Richard Byng, Jose M. Valderas, Nicky Britten, and Helen Lloyd

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The transcription factor GATA4 is overexpressed in malignant meningioma enhancing proliferation via downregulation of miR-15 family members, C Negroni, E Ercolano, C Adams, D Hilton, D Baiz, and CO Hanemann

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Trends of testing for and diagnosis of α 1 -antitrypsin deficiency in the UK: more testing is needed, JB Soriano, SJ Lucas, R Jones, M Miravitlles, and et al

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Under representation of people with epilepsy and intellectual disability in research, Rohit Shankar, Charles Rowe, Alje Van Hoorn, William Henley, Richard Laugharne, David Cox, Raj Pande, Ashok Roy, and Josemir W. Sander

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B cell development is critically dependent on NFATc1 activity, Sabrina Giampaolo, Gabriela Wójcik, Stefan Klein-Hessling, Edgar Serfling, and Amiya K. Patra

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Supplementary search methods were more effective and offered better value than bibliographic database searching: a case study from public health and environmental enhancement., Chris Cooper, Rebecca Lovell, Kerryn Husk, Andrew Booth, and Ruth Garside

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Orbital infections: a complete cycle 7-year audit and a management guideline, M Atfeh, K Singh, and HS Khalil

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Confidentiality, anonymity and amnesty for midwives in distress seeking online support – Ethical?, S Pezaro, W Clyne, and C Gerada

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Correction to: Ret is essential to mediate GDNF’s neuroprotective and neuroregenerative effect in a Parkinson disease mouse model, Anja Drinkut, Karsten Tillack, Durga P. Meka, Jorg B. Schulz, Sebastian Kügler, and Edgar R. Kramer

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Health trainer-led motivational intervention plus usual care for people under community supervision compared with usual care alone: a study protocol for a parallel-group pilot randomised controlled trial (STRENGTHEN), Tom P. Thompson, Lynne Callaghan, Emma Hazeldine, Cath Quinn, Samantha Walker, Richard Byng, Gary Wallace, Siobhan Creanor, Colin Green, Annie Hawton, Jill Annison, Julia Sinclair, Jane Senior, and Adrian H. Taylor

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International consensus on quality standards for multiple sclerosis care: results from a modified Delphi process, J Hobart, A Bowen, L Eberhard, G Pepper, and G Giovannoni

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PO-511 High miR-9 levels represent a novel prognostic biomarker to predict development of malignant meningioma, D Baiz, C Negroni, S Ferluga, E Ercolano, C Adams, and OC Hanemann

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Targeting Gpr52 lowers mutant HTT levels and rescues Huntington's disease-associated phenotypes., Haikun Song, H Li, Shimeng Guo, Yuyin Pan, Yuhua Fu, Zijian Zhou, Z Li, Xue Wen, Xiaoli Sun, Bingqing He, Haifeng Gu, Quan Zhao, Cen Wang, Ping An, Shouqing Luo, Youhong Hu, Xin Xie, and Boxun Lu

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A pilot randomised controlled trial investigating a mindfulness-based stress reduction (MBSR) intervention in individuals with pulmonary arterial hypertension (PAH): the PATHWAYS study, RMR Tulloh, V Garratt, J Tagney, J Turner-Cobb, and et al

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Etiology and treatment of Parkinson Disease, E Kramer

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Physical activity for antenatal and postnatal depression in women attempting to quit smoking: randomised controlled trial, Amanda Daley, Muhammad Riaz, S Lewis, Paul Aveyard, Tim Coleman, Isaac Manyonda, Robert West, B Lewis, Bess Marcus, Adrian Taylor, Judith Ibison, Andrew Kent, and Michael Ussher

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Achieving Integrated Care for Older People: What Kind of Ship? Comment on “Achieving Integrated Care for Older People: Shuffling the Deckchairs or Making the System Watertight for the Future?”, Rod Sheaff

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Ultramicroscopy/lightsheet-microscopy in dementia, E Kramer

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A systematic review and consensus definitions for standardised end-points in perioperative medicine: pulmonary complications, RM Pearse and StEP-COMPAC Group

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Children’s Compliance With Wrist-Worn Accelerometry Within a Cluster-Randomized Controlled Trial: Findings From the Healthy Lifestyles Programme, L Price, K Wyatt, J Lloyd, C Abraham, and et al

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Desperately seeking outcomes: quantifying the effectiveness of community mental healthcare using Health of the Nation Outcome Scales, R Laugharne, S Eaves, A Mascas, K Psatha, and et al

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Desperately seeking outcomes: Quantifying the effectiveness of community mental healthcare using Health of the Nation Outcome Scales, Richard Laugharne, Scott Eaves, Alin Mascas, Kiki Psatha, Gill Dinnis, Jonathan Trower, and Rohit Shankar

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Differential phosphorylation and n-terminal configuration of capsid subunits in parvovirus assembly and viral trafficking, J Gil-Ranedo, E Hernando, N Valle, L Riolobos, B Maroto, and JM Almendral

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Evaluating the development of medical revalidation in England and its impact on organisational performance and medical practice: overview report, J Archer, K Bloor, C Bojke, A Boyd, M Bryce, J Ferguson, N Gutacker, C Hillier, K Luscombe, T Price, de Bere S Regan, A Tazzyman, J Tredinnick-Rowe, and K Walshe

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‘It's a silver lining’: A template analysis of satisfaction and quality of life following post‐mastectomy breast reconstruction, H Matthews, A Turner, I Williamson, and W Clyne

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Mental Health in UK Biobank - development, implementation and results from an online questionnaire completed by 157,366 participants, WE Lee, K Davis, J Coleman, M Adams, and et al

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Personal wellbeing networks, social capital and severe mental illness: findings from an exploratory study, Daryl Sweet, Richard Byng, Martin Webber, Doyo Gragn Enki, Ian Porter, John Larsen, Peter Huxley, and Vanessa Pinfold

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UMbRELLA: Evaluating the regulatory impacts of medical revalidation – final report., J Archer, N Cameron, M Lewis, M Marshall, J O'Hanlon, de Bere S Regan, K Walshe, R Baines, A Boyd, M Bryce, J Ferguson, E Gabe-Thomas, S Holmes, M Lalani, T Price, P Rae, M Roberts, S Stevens, A Tazzyman, J Tredinnick-Rowe, J Wakeling, and D Zahra

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The International Landscape of Medical Licensing Examinations: A Typology Derived From a Systematic Review, Tristan Price, Nick Lynn, Lee Coombes, Martin Roberts, Tom Gale, de Bere S Regan, and Julian Archer

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Has the time come to stratify and score SUDEP risk to inform people with epilepsy of their changes in safety?, Rohit Shankar, Craig Newman, Alistair Gales, Brendan N. McLean, Jane Hanna, Samantha Ashby, Matthew C. Walker, and Josemir W. Sander

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IMPACT OF DEMENTIA CARE HOME LEARNING COMMUNITY IN DEMENTIA CARE HOMES IN TORBAY, DEVON, UK, A Rana, D Somerfield, and R Sheaff

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Using Social Media to Generate and Collect Primary Data: The #ShowsWorkplaceCompassion Twitter Research Campaign, W Clyne, S Pezaro, K Deeny, and R Kneafsey

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A Case of Invasive Sinonasal Carcinosarcoma: The Importance of Early Detection, J Yuen, V Varadarajan, M Stavrakas, S Muquit, and H Khalil

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Moral narratives and mental health: rethinking understandings of distress and healthcare support in contexts of austerity and welfare reform, Felicity Thomas, Lorraine Hansford, Joseph Ford, Katrina Wyatt, Rosemarie McCabe, and Richard Byng

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Discrimination, harassment and non-reporting in UK medical education, Jonathan Broad, Marion Matheson, Fabienne Verrall, Anna K. Taylor, Daniel Zahra, Louise Alldridge, and Gene Feder

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The Evolving Purposes of Medical Revalidation in the United Kingdom: A Qualitative Study of Professional and Regulatory Narratives, Abigail Tazzyman, Jane Ferguson, Kieran Walshe, Alan Boyd, John Tredinnick-Rowe, Charlotte Hillier, De Bere S Regan, and Julian Archer

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Interventions for reducing unplanned paediatric admissions: an observational study in one hospital, Kerryn Husk, Vashti Berry, Richard Tozer, Gina Skipwith, Robert Radmore, Susan Ball, Obioha C. Ukoumunne, and Stuart Logan

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Prescribing gardening and conservation activities for health and wellbeing in older people, Kerryn Husk, Rebecca Lovell, and Ruth Garside

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Implication of Major Adverse Postoperative Events and Myocardial Injury on Disability and Survival: A Planned Subanalysis of the ENIGMA-II Trial., WS Beattie and et al

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The Role of Pedagogy in Clinical Education, J Tredinnick-Rowe