Browse research from the Peninsula Medical School.

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Submissions from 2020

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Engaging Young People During the COVID-19 Pandemic, F Green, T Hobbs, N Axford, D Ellis, J Mannes, M Murphy, R Lily, L Burns, S Rybczynska-Bunt, T Thompson, and J Tredinnick-Rowe

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Step Together Integrating Care for People with Epilepsy and a Learning Disability, Rohit Shankar, Sarah Mitchell, Mark Scheepers, Ashley Liew, Helen Cross, Brendan Mclean, Phil Tittensor, Dominic Slowie, Helen Toker-Lester, Angie Pullen, Matthew C. Walker, Josemir W. Sander, Ashok Roy, Hannah Cock, and Regi Alexander

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Barriers and Enablers in Implementing Electronic Consultations in Primary Care: Scoping Review, Rebecca Baines, John Tredinnick-Rowe, Ray Jones, and Arunangsu Chatterjee

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Comparing endocrown restorations on permanent molars and premolars: a systematic review and meta-analysis, RM Thomas, A Kelly, N Tagiyeva, and S Kanagasingam

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Intergroup ‘Skype’ Quiz Sessions in Care Homes to Reduce Loneliness and Social Isolation in Older People, Sonam Zamir, Catherine Hennessy, Adrian Taylor, and Ray Jones

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Integration and Comparison of Transcriptomic and Proteomic Data for Meningioma, Jemma Dunn, Vasileios P. Lenis, David A. Hilton, Rolf Warta, Christel Herold-Mende, C. Oliver Hanemann, and Matthias E. Futschik

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A qualitative evaluation of the effect of a longitudinal dementia education programme on healthcare student knowledge and attitudes, S Daley, Y Feeney, W Grosvenor, M Hebditch, and et al

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COVID-19 deaths in people with intellectual disability in the UK and Ireland: descriptive study, B Perera, R Laugharne, W Henley, A Zabel, and et al

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How accessible and acceptable are current GP referral mechanisms for IAPT for low-income patients? Lay and primary care perspectives, F. Thomas, L. Hansford, J. Ford, K. Wyatt, R. McCabe, and R. Byng

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What works in managing complex conditions in older people in primary and community care? A state‐of‐the‐art review, R Frost, G Rait, A Wheatley, J Wilcock, and et al

Putative Membrane Receptors Contribute to Activation and Efficient Signaling of Mitogen-Activated Protein Kinase Cascades during Adaptation of Aspergillus fumigatus to Different Stressors and Carbon Sources, LP Silva, D Frawley, LJD Assis, C Tierney, AB Fleming, O Bayram, and GH Goldman

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'You're just a locum': professional identity and temporary workers in the medical profession, Jane Ferguson, Abigail Tazzyman, Kieran Walshe, Marie Bryce, Alan Boyd, Julian Archer, Tristan Price, and John Tredinnick-Rowe

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Introducing the Parkinson’s KinetiGraph into Routine Parkinson’s Disease Care: A 3-Year Single Centre Experience, Thea Dominey, Angie A. Kehagia, Terry Gorst, Emma Pearson, Fiona Murphy, Emma King, and Camille Carroll

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COVID-19 deaths in people with intellectual disability in the UK and Ireland: Descriptive study, Bhathika Perera, Richard Laugharne, William Henley, Abigail Zabel, Kirsten Lamb, David Branford, Ken Courtanay, Regi Alexander, Kiran Purandare, Anusha Wijeratne, Vishwa Radhakrishnan, Eileen Mcnamara, Youshan Daureeawoo, Indermeet Sawhney, Mark Scheepers, Gordon Taylor, and Rohit Shankar

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Selective Overexpression of EAAT3 in Midbrain Dopamine Neurons Leads to Increased OCD-like Behaviors., N Greene, M Chohan, J Kopelman, E Kramer, S Ahmari, and J Veenstra-VanderWeele

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Conservative or liberal oxygen therapy in adults after cardiac arrest, Paul J. Young, Michael Bailey, Rinaldo Bellomo, Stephen Bernard, Janet Bray, Pekka Jakkula, Markku Kuisma, Diane Mackle, Daniel Martin, Jerry P. Nolan, Rakshit Panwar, Matti Reinikainen, Markus B. Skrifvars, and Matt Thomas

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Knowledge, skills and attitudes of older people and staff about getting up from the floor following a fall: a qualitative investigation, Dawn R. Swancutt, Suzy V. Hope, Benjamin P. Kent, Maria Robinson, and Victoria A. Goodwin

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Do the severity of Intellectual Disability and /or the presence of neurodevelopmental disorders influence the onset of dementia in people with Down syndrome?, Merryn Anderson, Katy Oak, Rebecca Goodey, Karen Dodd, and Rohit Shankar

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Human adaptation to hypoxia in critical illness, Helen T. McKenna, Andrew J. Murray, and Daniel S. Martin

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Exploring patient and public involvement (PPI) and co-production approaches in mental health research: learning from the PARTNERS2 research programme, Dawn Allen, Laura Gill, and Charley Hobson-Merrett

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Task-shifted approaches to postdiagnostic dementia support: a qualitative study exploring professional views and experiences, A Wheatley, C Bamford, G Brunskill, K Harrison Dening, and et al

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An anaesthetic and intensive care perspective on infection control measures for the prevention of airborne transmission of SARS-CoV-2, HR O'Mahony and Daniel S. Martin

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UK psychiatrists' experience of withdrawal of antipsychotics prescribed for challenging behaviours in adults with intellectual disabilities and/or autism, Shoumitro Deb, Tom Nancarrow, Bharati Limbu, Rory Sheehan, Mike Wilcock, David Branford, Ken Courtenay, Bhathika Perera, and Rohit Shankar

Epilepsy, an orphan disorder within the neurodevelopmental family, Rohit Shankar, Bhathika Perera, and Rhys H. Thomas

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European perspective of perampanel response in people with Intellectual Disability, Jon Allard, William Henley, Francesca Snoeijen-Schouwenaars, Jans van Ool, In Tan, H. Jurgen Schelhaas, Marian H.J.M. Majoie, Sharon Hudson, Brendan McLean, and Rohit Shankar

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Favourable outcomes for high-risk diffuse large B-cell lymphoma (IPI 3–5) treated with front-line R-CODOX-M/R-IVAC chemotherapy: results of a phase 2 UK NCRI trial, AK McMillan, EH Phillips, AA Kirkwood, S Barrans, and et al

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Oxygen targets in the intensive care unit during mechanical ventilation for acute respiratory distress syndrome: a rapid review, Andrew F. Cumpstey, Alex H. Oldman, Andrew F. Smith, Daniel Martin, and Michael P.W. Grocott

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UK psychiatrists’ experience of withdrawal of antipsychotics prescribed for challenging behaviours in adults with intellectual disabilities and/or autism, S Deb, T Nancarrow, B Limbu, R Sheehan, and et al

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Contributions of Fat and Carbohydrate Metabolism to Glucose Homeostasis in Childhood Change With Age and Puberty: A 12-Years Cohort Study (EARLYBIRD 77), Ornella Cominetti, Joanne Hosking, Alison Jeffery, Jonathan Pinkney, and Francois Pierre Martin

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ACCEPT - combining acalabrutinib with rituximab, cyclophosphamide, doxorubicin, vincristine and prednisolone (R-CHOP) for Diffuse Large B-cell Lymphoma (DLBCL): study protocol for a Phase Ib/II open-label non-randomised clinical trial, A Davies, S Barrans, C Burton, K Mercer, and et al

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Adult liver transplantation: A UK clinical guideline - part 1: pre-operation, Charles Millson, Aisling Considine, Matthew E. Cramp, Andrew Holt, Stefan Hubscher, John Hutchinson, Kate Jones, Joanna Leithead, Steven Masson, Krish Menon, Darius Mirza, James Neuberger, Raj Prasad, Anthony Pratt, Wendy Prentice, Liz Shepherd, Ken Simpson, Doug Thorburn, Rachel Westbrook, and Dhiraj Tripathi

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A Systematic Approach to Review of in vitro Methods in Brain Tumour Research (SAToRI-BTR): Development of a Preliminary Checklist for Evaluating Quality and Human Relevance, Mike Bracher, GJ Pilkington, C. Oliver Hanemann, and K Pilkington

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Final 5-year findings from the phase 3 HELIOS study of ibrutinib plus bendamustine and rituximab in patients with relapsed/refractory chronic lymphocytic leukemia/small lymphocytic lymphoma, GAM Fraser, S Rule, and et al

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Awareness of bone health risks in people with epilepsy and intellectual disability, Indermeet Sawhney, Asif Zia, Bahar Yazdi, and Rohit Shankar

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FGF5 Regulates Schwann Cell Migration and Adhesion, Bing Chen, Rong Hu, Qing Min, Yankun Li, David B. Parkinson, and Xin Peng Dun

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Promoting learning from null or negative results in prevention science trials, Nick Axford, Vashti Berry, Jenny Lloyd, Tim Hobbs, and Katrina Wyatt

Topological features of integrin adhesion complexes revealed by multiplexed proximity biotinylation, Megan R. Chastney, Craig Lawless, JD Humphries, Stacey Warwood, Matthew C. Jones, David Knight, Claus Jorgensen, and MJ Humphries

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Barriers and facilitators to GP–patient communication about emotional concerns in UK primary care: a systematic review, Daisy Parker, Richard Byng, Chris Dickens, Debbie Kinsey, and Rose McCabe

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Dementia prevention, intervention, and care: 2020 report of the Lancet Commission, G Livingston, J Huntley, A Sommerlad, and et al

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Developing a roadmap to improve trial delivery for underserved groups: results from a UK multi-stakeholder process, Miles D. Witham, Eleanor Anderson, Camille Carroll, Paul M. Dark, Kim Down, Alistair S. Hall, Joanna Knee, Rebecca H. Maier, Gail A. Mountain, Gary Nestor, Laurie Oliva, Sarah R. Prowse, Amanda Tortice, James Wason, and Lynn Rochester

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The Effectiveness of a Community-Based Mentoring Program for Children Aged 5–11 Years: Results from a Randomized Controlled Trial, Nick Axford, Gretchen Bjornstad, Justin Matthews, Laura Whybra, Vashti Berry, Obioha C. Ukoumunne, Tim Hobbs, Zoe Wrigley, Lucy Brook, Rod Taylor, Tim Eames, Angeliki Kallitsoglou, Sarah Blower, and Georgina Warner

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Effect of zinc treatment on clinical outcomes in patients with liver cirrhosis: A systematic review and meta-analysis, Huey K. Tan, Adam Streeter, Matthew E. Cramp, and Ashwin D. Dhanda

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Oxidative stress in alcohol-related liver disease, Huey K. Tan, Euan Yates, Kristen Lilly, and Ashwin D. Dhanda

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Efficacy and Safety of Alemtuzumab Through 9 Years of Follow-up in Patients with Highly Active Disease: Post Hoc Analysis of CARE-MS I and II Patients in the TOPAZ Extension Study, Tjalf Ziemssen, Ann D. Bass, Regina Berkovich, Giancarlo Comi, Sara Eichau, Jeremy Hobart, Samuel F. Hunter, Christopher LaGanke, Volker Limmroth, Daniel Pelletier, Carlo Pozzilli, Sven Schippling, Livia Sousa, Anthony Traboulsee, Bernard M.J. Uitdehaag, Wijmeersch B Van, Zia Choudhry, Nadia Daizadeh, and Barry A. Singer

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Epilepsy, anti-seizure medication, intellectual disability and challenging behaviour – Everyone's business, no one's priority, M. O. Kinney, V. Chester, S. Tromans, R. T. Alexander, H. Angus-Leppan, M. Bagary, H. Cock, J. Devapriam, A. Hassiotis, M. Mula, M. Reuber, H. Ring, A. Roy, M. Scheepers, and R. Shankar

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Migrating Schwann cells direct axon regeneration within the peripheral nerve bridge, Qing Min, David B. Parkinson, and Xin Peng Dun

Clinical guidance on pharmacotherapy for the treatment of attention-deficit hyperactivity disorder (ADHD) for people with intellectual disability, Jonjo Miller, Bhathika Perera, and Rohit Shankar

Creating Capable Communities for People with Intellectual Disabilities: Challenges and Opportunities, Rohit Shankar, Sarah Lennard, Richard Sharpe, Rebecca Goodey, and Sharon Hudson

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Integrating the voluntary sector in personalised care: mixed methods study of the outcomes from wellbeing co-ordination for adults with complex needs, Felix Gradinger, Julian Elston, Sheena Asthana, Chloe Myers, Sue Wroe, and Richard Byng

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State of the Art and Future Challenges in Multiple Sclerosis Research and Medical Management: An Insight into the 5th International Porto Congress of Multiple Sclerosis, María José Sá, dos Reis R Soares, Ayse Altintas, Elisabeth Gulowsen Celius, Claudia Chien, Giancarlo Comi, Francesc Graus, Jan Hillert, Jeremy Hobart, Gulfaraz Khan, Najib Kissani, Dawn Langdon, Maria Isabel Leite, Darin T. Okuda, Jacqueline Palace, Regina María Papais-Alvarenga, Inês Mendes-Pinto, and Fu Dong Shi

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EEG Markers in Emotionally Unstable Personality Disorder—A Possible Outcome Measure for Neurofeedback: A Narrative Review, Cailín Boland, Virupakshi Jalihal, Catriona Organ, Katy Oak, Brendan McLean, Richard Laugharne, Wessel Woldman, Randy Beck, and Rohit Shankar

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Creating Capable Communities for People with Intellectual Disabilities: Challenges and Opportunities, S Lennard, R Sharpe, R Goodey, S Hudson, and R Shankar

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Measuring quality of life in ALS/MND: validation of the WHOQOL-BREF, Carolyn A. Young, Roger Mills, Ammar Al-Chalabi, Georgina Burke, Siddharthan Chandran, David J. Dick, John Ealing, C. Oliver Hanemann, Timothy Harrower, Christopher J. Mcdermott, Tahir Majeed, Ashwin Pinto, Kevin Talbot, Jannette Walsh, Timothy L. Williams, and Alan Tennant

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General practitioners’ and psychiatrists’ attitudes towards antidepressant withdrawal, J McCabe, M Wilcock, K Atkinson, R Laugharne, and R Shankar

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Open letter from UK based academic scientists to the secretaries of state for digital, culture, media and sport and for health and social care regarding the need for independent funding for the prevention and treatment of gambling harms, Heather Wardle, James Banks, Paul Bebbington, Lindsey Blank, Jones OBE H Bowden, Stephanie Bramley, Christopher Bunn, Emma Casey, Rebecca Cassidy, Samuel R. Chamberlain, James Close, Nathan Critchlow, Fiona Dobbie, Carolyn Downs, Simon Dymond, Emanuele Fino, Elizabeth Goyder, Cindy Gray, Mark Griffiths, Peter Grindrod, Lee Hogan, Alice Hoon, Kate Hunt, Richard James, Bev John, Jill Manthorpe, Jim McCambridge, David McDaid, Martin McKee, Sally McManus, Antony Moss, Caroline Norrie, David J. Nutt, Jim Orford, Rob Pryce, Richard Purves, Gerda Reith, A Roberts, E Roberts, Gareth Roderique-Davies, J Rogers, RD Rogers, Stephen Sharman, John Strang, Richard Tunney, John Turner, Robert West, and David Zendle

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Port dumping and participation in England: Developing an ecosystem approach through local ecological knowledge, Jeremy Anbleyth-Evans, Shaw Nozaki Lacy, Carolina Aguirre-Muñoz, and John Tredinnick-Rowe

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Rationing bytes: managing demand for digital forensic examinations, Brian Rappert, Hannah Wheat, and Dana Wilson-Kovacs

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The Potential of MLN3651 in Combination with Selumetinib as a Treatment for Merlin-Deficient Meningioma, Rimmer J Lyons, Emanuela Ercolano, Daniele Baiz, Mahindra Makhija, Allison Berger, Todd Sells, Steve Stroud, David Hilton, Claire L. Adams, and C. Oliver Hanemann

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Research with older people in a world with COVID-19: identification of current and future priorities, challenges and opportunities, Sarah J. Richardson, Camille B. Carroll, Jacqueline Close, Adam L. Gordon, J O'Brien, Terence J. Quinn, Lynn Rochester, Avan A. Sayer, Susan D. Shenkin, der Velde N van, Jean Woo, and Miles D. Witham

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Trace element deficiency is highly prevalent and associated with infection and mortality in patients with alcoholic hepatitis, Ashwin Dhanda, Stephen Atkinson, Nikhil Vergis, Doyo Enki, Andrew Fisher, Robert Clough, Matthew Cramp, and Mark Thursz

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In reply to: Helmich and Bloem (2020) “The Impact of the COVID-19 Pandemic on Parkinson’s Disease: Hidden Sorrows and Emerging Opportunities”, Emma Edwards and Camille Carroll

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Admission Decision-Making in Hospital Emergency Departments: The Role of the Accompanying Person, Susanna Rance, Debra Westlake, Heather Brant, Ingrid Holme, Ruth Endacott, Jonathan Pinkney, and Richard Byng

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General practitioners' and psychiatrists' attitudes towards antidepressant withdrawal, Joanne McCabe, Mike Wilcock, Kate Atkinson, Richard Laugharne, and Rohit Shankar

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Marked variability in bioactivity between commercially available bovine colostrum for human use; implications for clinical trials, RJ Playford, M Cattell, and T Marchbank

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HuR/ELAVL1 drives malignant peripheral nerve sheath tumor growth and metastasis, Marta Palomo-Irigoyen, Encarni Pérez-Andrés, Marta Iruarrizaga-Lejarreta, Adrián Barreira-Manrique, Miguel Tamayo-Caro, Laura Vila-Vecilla, Leire Moreno-Cugnon, Nagore Beitia, Daniela Medrano, David Fernández-Ramos, Juan José Lozano, Satoshi Okawa, José L. Lavín, Natalia Martín-Martín, James D. Sutherland, Juan VG de, Monika Gonzalez-Lopez, Nuria Macías-Cámara, David Mosén-Ansorena, Liyam Laraba, CO Hanemann, Emanuela Ercolano, David B. Parkinson, Christopher W. Schultz, Marcos J. Araúzo-Bravo, Alex M. Ascensión, Daniela Gerovska, Haizea Iribar, Ander Izeta, Ander Izeta, Philipp Krastel, Alessandro Provenzani, Pierfausto Seneci, Ruben D. Carrasco, Sol A Del, María Luz Martinez-Chantar, Rosa Barrio, Eduard Serra, Conxi Lazaro, Adrienne M. Flanagan, Myriam Gorospe, Nancy Ratner, Ana M. Aransay, Arkaitz Carracedo, Marta Varela-Rey, and Ashwin Woodhoo

Management evaluation of metastasis in the brain (MEMBRAIN)—a United Kingdom and Ireland prospective, multicenter observational study, J Jung, J Tailor, E Dalton, LJ Glancz, J Roach, R Zakaria, S Lammy, A Chari, KP Budohoski, LJ Livermore, K Yu, MD Jenkinson, PM Brennan, L Brazil, C Bunce, E Bourmpaki, K Ashkan, F Vergani, S Achawa, R Al-Mahfoudh, E Albanese, M Amoo, R Ashida, K Benton, H Bhatt, I Coulter, P D’Urso, A Dapaah, K Dawson, and G Dobson

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GDNF and Parkinson’s Disease: Where Next? A Summary from a Recent Workshop, Roger A. Barker, A Bjorklund, Don M. Gash, Alan Whone, Laar A Van, Jeffrey H. Kordower, Krystof Bankiewicz, Karl Kieburtz, Mart Saarma, Sigrid Booms, Henri J. Huttunen, Adrian P. Kells, Massimo S. Fiandaca, A. Jon Stoessl, David Eidelberg, Howard Federoff, Merja H. Voutilainen, David T. Dexter, Jamie Eberling, Patrik Brundin, Lyndsey Isaacs, Leah Mursaleen, Eros Bresolin, Camille Carroll, Alasdair Coles, Brian Fiske, Helen Matthews, Codrin Lungu, Richard K. Wyse, Simon Stott, and Anthony E. Lang

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Challenges to well-being for general practice trainee doctors: a qualitative study of their experiences and coping strategies, Sarah Ansell, James Read, and Marie Bryce

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A historical database cohort study addressing the clinical patterns prior to idiopathic pulmonary fibrosis (IPF) diagnosis in UK primary care, R Jones, D Thickett, J Voorham, and D Price

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Defining the characteristics of intermediate care models including transitional care: an international Delphi study, Duygu Sezgin, Rónán O’Caoimh, Mark R. O’Donovan, Mohamed A. Salem, Siobhán Kennelly, Luz Lopez Samaniego, Cristina Arnal Carda, Rafael Rodriguez-Acuña, Marco Inzitari, Teija Hammar, Claire Holditch, Janet Prvu Bettger, Martin Vernon, Áine Carroll, Felix Gradinger, Gaston Perman, Martin Wilson, Antoine Vella, Antonio Cherubini, Helen Tucker, Maria Pia Fantini, Graziano Onder, Regina Roller-Wirnsberger, Luis Miguel Gutiérrez-Robledo, Matteo Cesari, Paula Bertoluci, Magdalena Kieliszek, der Vlegel-Brouwer W van, Michelle Nelson, Leocadio Rodríguez Mañas, Eleftheria Antoniadou, François Barriere, Sebastian Lindblom, Grace Park, Isidoro Pérez, Dolores Alguacil, Douglas Lowdon, Maria Eugenia Alkiza, Cristina Alonso Bouzon, John Young, Ana Carriazo, Aaron Liew, and Anne Hendry

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Help to Overcome Problems Effectively for Cancer Survivors: Development and Evaluation of a Digital Self-Management Program, F Martin, H Wright, L Moody, B Whiteman, and et al

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How healthcare systems shape a purchaser’s strategies and actions when managing chronic care, Bart A.C. Noort, Kees Ahaus, der Vaart T van, Naomi Chambers, and Rod Sheaff

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Clinical features and genetic risk of demyelination following anti-TNF treatment, Simeng Lin, Harry D. Green, Peter Hendy, Neel M. Heerasing, Neil Chanchlani, Benjamin Hamilton, Gareth J. Walker, Graham A. Heap, Jeremy Hobart, Roswell J. Martin, Alasdair J. Coles, Peter M. Irving, Guy Chung-Faye, J. R.Fraser Cummings, Ellina Lytvyak, Vibeke Andersen, Andrew R. Wood, Jessica Tyrrell, Robin N. Beaumont, Michael N. Weedon, Nicholas A. Kennedy, Alexander Spiers, Timothy Harrower, James R. Goodhand, and Tariq Ahmad

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Speech Therapy in the Treatment of Globus Pharyngeus: Development of a Mobile Application to Improve Patient Access, Hisham Khalil, D Grech-Marguerat, Marios Stavrakas, Abdulaziz Abushaala, Robert Hart, and Arunangsu Chatterjee

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Favourable outcomes for high‐risk Burkitt lymphoma patients (IPI 3‐5) treated with rituximab plus CODOX‐M/IVAC: Results of a phase 2 UK NCRI trial, EH Phillips, C Burton, AA Kirkwood, S Barrans, and et al

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Perioperative Quality Initiative (POQI) consensus statement on fundamental concepts in perioperative fluid management: fluid responsiveness and venous capacitance, GS Martin, DA Kaufman, PE Marik, NI Shapiro, DZH Levett, J Whittle, DB MacLeod, D Chappell, J Lacey, T Woodcock, K Mitchell, MLNG Malbrain, TM Woodcock, D Martin, CHE Imray, MW Manning, H Howe, MPW Grocott, MG Mythen, TJ Gan, and TE Miller

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Is It Possible to Conduct a Multi-Arm Multi-Stage Platform Trial in Parkinson’s Disease: Lessons Learned from Other Neurodegenerative Disorders and Cancer, Marie Louise Zeissler, Vivien Li, Mahesh K.B. Parmar, and Camille Buchholz Carroll

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The effectiveness of the KiVa bullying prevention program in Wales, UK: results from a pragmatic cluster randomised controlled trial, Nick Axford, Gretchen Bjornstad, Suzy Clarkson, Obioha C. Ukoumunne, Zoe Wrigley, Justin Matthews, and Vashti Berry

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Ben Fine. Micro-economics. A Critical Companion. London 2016 (Pluto), W Sheaff

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Resource pack to support workplace compassion, W Clyne and K Deeny

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Preferences of nursing and medical students for working with older adults and people with dementia: a systematic review, M Hebditch, S Daley, J Wright, and et al

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Postoperative Remote Automated Monitoring and Virtual Hospital-to-Home Care System Following Cardiac and Major Vascular Surgery: User Testing Study, M McGillion, C Ouellette, A Good, and et al

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Valproate risk form—Surveying 215 clinicians involving 4775 encounters, Heather Angus-Leppan, Melika M. Moghim, Hannah Cock, Lucy Kinton, Marie Synnott Wells, and Rohit Shankar

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Correction to:: Do pain, anxiety and depression influence quality of life for people with amyotrophic lateral sclerosis/motor neuron disease? A national study reconciling previous conflicting literature (Journal of Neurology, (2020), 267, 3, (607-615), 10.1007/s00415-019-09615-3), Rhiannon Edge, Roger Mills, Alan Tennant, Peter J. Diggle, Carolyn A. Young, Ammar Al-Chalabi, Timothy L. Williams, David J. Dick, Kevin Talbot, Georgina Burke, Tahir Majeed, John Ealing, Christopher J. McDermott, Ashwin Pinto, Siddharthan Chandran, Jannette Walsh, C. Oliver Hanemann, and Timothy Harrower

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Do pain, anxiety and depression influence quality of life for people with amyotrophic lateral sclerosis/motor neuron disease? A national study reconciling previous conflicting literature, the TONiC study group, Rhiannon Edge, Roger Mills, Alan Tennant, Peter J. Diggle, Carolyn A. Young, Ammar Al-Chalabi, Timothy L. Williams, David J. Dick, Kevin Talbot, Georgina Burke, Tahir Majeed, John Ealing, Christopher J. McDermott, Ashwin Pinto, Siddharthan Chandran, Jannette Walsh, Oliver Hanemann, and Timothy Harrower

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Mental health services for adults with mild intellectual disability, Rohit Shankar, Fabian Haut, and Ken Courtenay

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Women’s Digital Care Record report, Health Education England

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Adult liver transplantation: UK clinical guideline - part 2: surgery and post-operation, Charles Millson, Aisling Considine, Matthew E. Cramp, Andrew Holt, Stefan Hubscher, John Hutchinson, Kate Jones, Joanna Leithead, Steven Masson, Krish Menon, Darius Mirza, James Neuberger, Raj Prasad, Anthony Pratt, Wendy Prentice, Liz Shepherd, Ken Simpson, Doug Thorburn, Rachel Westbrook, and Dhiraj Tripathi

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Genome-wide association study of pain in Parkinson's disease implicates TRPM8 as a risk factor, Nigel M. Williams, Leon Hubbard, Cynthia Sandor, Caleb Webber, Hannah Hendry, Camille Carroll, Michael Lawton, K. Ray Chaudhuri, Huw Morris, Michele T. Hu, Donald G. Grosset, Christopher Kobylecki, and Monty Silverdale

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Lacosamide in the general population and in people with intellectual disability: Similar responses?: Similar responses?, Jon Allard, William Henley, Brendan Mclean, Adrian Sellers, Sharon Hudson, Sanjeev Rajakulendran, Adrian Pace, Sarah Pashley, Melissa Maguire, Monica Mohan, Shan Ellawela, Phil Tittensor, Sunil Ram, Manny Bagary, and Rohit Shankar

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Recovery from recurrent depression with mindfulness-based cognitive therapy and antidepressants: a qualitative study with illustrative case studies, Alice Tickell, Richard Byng, Catherine Crane, Felix Gradinger, Rachel Hayes, James Robson, Jessica Cardy, Alice Weaver, Nicola Morant, and Willem Kuyken

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Reply to Tasker and to Lellouche and L’Her, Edward Palmer, Daniel Martin, Mervyn Singer, and Steve Harris

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Managerial workarounds in three European DRG systems, Rod Sheaff, Verdiana Morando, Naomi Chambers, Mark Exworthy, Ann Mahon, Richard Byng, and Russell Mannion

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Patients’ experiences of seeking help for emotional concerns in primary care: doctor as drug, detective and collaborator, Daisy Parker, Richard Byng, Chris Dickens, and Rose McCabe

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A Rapid Robust Method for Subgrouping Non-NF2 Meningiomas According to Genotype and Detection of Lower Levels of M2 Macrophages in AKT1 E17K Mutated Tumours, Claire L. Adams, Emanuela Ercolano, Sara Ferluga, Agbolahan Sofela, Foram Dave, Caterina Negroni, Kathreena M. Kurian, David A. Hilton, and C. Oliver Hanemann

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Capturing the role of context in complex system change: an application of the Canadian Context and Capabilities for Integrating Care (CCIC) Framework to the English Context, Sheena Asthana, Felix Gradinger, Julian Elston, Susan Martin, and Richard Byng

Expanding Clinical Presentations Due to Variations in THOC2 mRNA Nuclear Export Factor, Raman Kumar, Elizabeth Palmer, Alison E. Gardner, Renee Carroll, Siddharth Banka, Ola Abdelhadi, Dian Donnai, Ype Elgersma, Cynthia J. Curry, Alice Gardham, Mohnish Suri, Rishikesh Malla, Lauren Ilana Brady, Mark Tarnopolsky, Dimitar N. Azmanov, Vanessa Atkinson, Michael Black, Gareth Baynam, Lauren Dreyer, Robin Z. Hayeems, Christian R. Marshall, Gregory Costain, Marja W. Wessels, Julia Baptista, James Drummond, Melanie Leffler, Michael Field, and Jozef Gecz

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Improving epilepsy management with EpSMon: A Templar to highlight the multifaceted challenges of incorporating digital technologies into routine clinical practice, C Newman, S Ashby, B McLean, and R Shankar

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On brain atlas choice and automatic segmentation methods: a comparison of MAPER & FreeSurfer using three atlas databases, SN Yaakub, RA Heckemann, SS Keller, and et al

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Recurrent TTN metatranscript‐only c.39974–11T>G splice variant associated with autosomal recessive arthrogryposis multiplex congenita and myopathy, SJ Bryen, LJ Ewans, J Pinner, and et al