Browse research from the Peninsula Medical School.

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Submissions from 2020

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A novel lung health programme addressing awareness and behaviour-change aiming to prevent chronic respiratory diseases in rural Uganda: a two-year train-the-trainer programme, R Jones, B Kirenga, S Buteme, S Williams, and Gemert F van

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Applicability, safety, and biological activity of regulatory T cell therapy in liver transplantation, A Sánchez‐Fueyo, Gavin Whitehouse, Nathali Grageda, Matthew E. Cramp, Tiong Y. Lim, Marco Romano, Sarah Thirkell, Katie Lowe, Laura Fry, Julie Heward, Alex Kerr, Jakia Ali, Chris Fisher, Gillian Lewis, Andrew Hope, Elisavet Kodela, Mike Lyne, Farzin Farzaneh, Shahram Kordasti, I Rebollo‐Mesa, Lozano J Jose, Niloufar Safinia, Nigel Heaton, Robert Lechler, M Martínez‐Llordella, and Giovanna Lombardi

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Assessment of patients with lower urinary tract symptoms where an undiagnosed neurological disease is suspected: A report from an International Continence Society consensus working group, Marcus J. Drake, Holly A. Roy, Jeremy Nettleton, Camilla Blain, Catherine Dalton, Bilal Farhan, Ailton Fernandes, Petros Georgopoulos, Sabine Klepsch, John Lavelle, Evangelista Martinelli, Jalesh N. Panicker, Ivan Radoja, Christina Anastasia Rapidi, e Silva R Pereira, Katarina Tudor, and Adrian S. Wagg

Autism Spectrum Social Stories In Schools Trial 2 (ASSSIST2): study protocol for a randomised controlled trial analysing clinical and cost-effectiveness of Social Stories™ in primary schools, B Wright, C. Teige, J. Watson, R. Hodkinson, D. Marshall, D. Varley, V. Allgar, L. Mandefield, S. Parrott, E. Kingsley, R. Hargate, N. Mitchell, S Ali, D. McMillan, H. Wang, and C. Hewitt

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Book Review: Microeconomics: A Critical Companion by Ben Fine, R Sheaff

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British Obesity and Metabolic Surgery Society Guidelines on perioperative and postoperative biochemical monitoring and micronutrient replacement for patients undergoing bariatric surgery—2020 update, Mary O'Kane, Helen M. Parretti, Jonathan Pinkney, Richard Welbourn, Carly A. Hughes, Jessica Mok, Nerissa Walker, Denise Thomas, Jennifer Devin, Karen D. Coulman, Gail Pinnock, Rachel L. Batterham, Kamal K. Mahawar, Manisha Sharma, Alex I. Blakemore, Iris McMillan, and Julian H. Barth

Child mental health and resilience in the context of socioeconomic disadvantage: results from the Born in Bradford cohort study, Natalie Kirby, Barry Wright, and Victoria Allgar

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Cognition and its relation to brain health in patients with MS: Response to letter, Jeremy Hobart and Gavin Giovannoni

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Constitutive activation of the EGFR–STAT1 axis increases proliferation of meningioma tumor cells, Clemens O. Hanemann, Sara Ferluga, Daniele Baiz, David A. Hilton, Claire L. Adams, Emanuela Ercolano, Jemma Dunn, Kayleigh Bassiri, and Kathreena M. Kurian

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Contrasting impact of androgens on male and female adiposity, fat distribution and insulin resistance in childhood and adolescence (EarlyBird 75), Jade Chynoweth, Joanne Hosking, Alison Jeffery, and Jonathan Pinkney

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COVID-19: An update from England’s high consequence infectious diseases intensive care unit leads, Daniel Martin, Sarah Platt, Peter Hampshire, and Chris Meadows

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Disease severity accounts for minimal variance of quality of life in people with dementia and their carers: analyses of cross-sectional data from the MODEM study, N Farina, Derek King, C Burgon, S Berwald, E Bustard, Y Feeney, R Habibi, A Comas-Herrera, Martin Knapp, and S Banerjee

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Editorial: ‘Do we really need another review on the effects of physical activity on alcohol and other drug use disorders?’, Adrian H. Taylor, Tom P. Thompson, and Jane Horrell

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Effectiveness and safety of opicapone in Parkinson’s disease patients with motor fluctuations: the OPTIPARK open-label study, Patrício Soares-Da-Silva, Heinz Reichmann, Andrew Lees, José Francisco Rocha, Diogo Magalhães, and Camille Carroll

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Efficacy of three neuroprotective drugs in secondary progressive multiple sclerosis (MS-SMART): a phase 2b, multiarm, double-blind, randomised placebo-controlled trial, Jeremy Chataway, Angelis F De, Peter Connick, RA Parker, Domenico Plantone, Anisha Doshi, Nevin John, Jonathan Stutters, David MacManus, Carrasco F Prados, Frederik Barkhof, Sebastien Ourselin, Marie Braisher, Moira Ross, Gina Cranswick, Sue H. Pavitt, Gavin Giovannoni, Wheeler-Kingshott CA Gandini, Clive Hawkins, Basil Sharrack, Roger Bastow, Christopher J. Weir, Nigel Stallard, Siddharthan Chandran, Wheeler-Kingshott CAM Gandini, Thomas Williams, Tiggy Beyene, Vanessa Bassan, Alvin Zapata, Dawn Lyle, Thomas Williams, Marie Braisher, Tiggy Beyene, Vanessa Bassan, Alvin Zapata, Siddharthan Chandran, Peter Connick, Dawn Lyle, James Cameron, Daisy Mollison, Shuna Colville, Baljean Dhillon, Christopher J. Weir, RA Parker, Moira Ross, Gina Cranswick, Gavin Giovannoni, Sharmilee Gnanapavan, Richard Nicholas, Waqar Rashid, Julia Aram, Helen Ford, James Overell, Carolyn Young, Heinke Arndt, Martin Duddy, Joe Guadagno, Nikolaos Evangelou, Matthew Craner, Jacqueline Palace, Jeremy Hobart, Basil Sharrack, David Paling, Clive Hawkins, Seema Kalra, B McLean, Nigel Stallard, and Roger Bastow

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eHealth technologies and the know-do gap: exploring the role of knowledge mobilisation, Sheena Asthana, Rod Sheaff, Ray Jones, and Arunangsu Chatterjee

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Ensuring that COVID-19 Research is Inclusive - guidance from the NIHR INCLUDE project, Miles D. Witham, Eleanor Anderson, Camille B. Carroll, Paul M. Dark, Kim Down, Alistair S. Hall, Joanna Knee, Eamonn R. Maher, Rebecca H. Maier, Gail A. Mountain, Gary Nestor, JT O’Brien, Laurie Oliva, James Wason, and Lynn Rochester

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“Every structure we're taught goes out the window”: General practitioners' experiences of providing help for patients with emotional concerns', Daisy Parker, Richard Byng, Chris Dickens, and Rose McCabe

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FibroScan-AST (FAST) score for the non-invasive identification of patients with non-alcoholic steatohepatitis with significant activity and fibrosis: a prospective derivation and global validation study, Philip N. Newsome, Magali Sasso, Jonathan J. Deeks, Angelo Paredes, Jérôme Boursier, Wah Kheong Chan, Yusuf Yilmaz, Sébastien Czernichow, Ming Hua Zheng, Vincent Wai Sun Wong, Michael Allison, Emmanuel Tsochatzis, Quentin M. Anstee, David A. Sheridan, Peter J. Eddowes, Indra N. Guha, Jeremy F. Cobbold, Valérie Paradis, Pierre Bedossa, Véronique Miette, Céline Fournier-Poizat, Laurent Sandrin, and Stephen A. Harrison

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GATA-4, a potential novel therapeutic target for high-grade meningioma, regulates miR-497, a potential novel circulating biomarker for high-grade meningioma, C. Oliver Hanemann, Caterina Negroni, David A. Hilton, Emanuela Ercolano, Claire L. Adams, Kathreena M. Kurian, and Daniele Baiz

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Home Based Care: A care pathway innovation for Parkinson's disease, E Edwards, R Partridge, U Ankeny, J Langley, S Whipps, J Whipps, J Rideout, A Evans, S Bentley, M Swabey, H Matthews, N Stevens, R Chivers, T Dominey, K Triscott, and C Carroll

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Impact of socioeconomic status on participation and outcomes in the Salford Lung Studies, R Jones, A Nicholls, D Browning, ND Bakerly, A Woodcock, J Vestbo, D Leather, L Jacques, J Lay-Flurrie, H Svedsater, and S Collier

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Implementing large-system, value-based healthcare initiatives: a realist study protocol for seven natural experiments, Mitchell N. Sarkies, Emilie Francis-Auton, Janet C. Long, Andrew Partington, Chiara Pomare, Hoa Mi Nguyen, Wendy Wu, Johanna Westbrook, Richard O. Day, Jean Frederic Levesque, Rebecca Mitchell, Frances Rapport, Henry Cutler, Yvonne Tran, Robyn Clay-Williams, Diane E. Watson, Gaston Arnolda, Peter D. Hibbert, Reidar Lystad, Virginia Mumford, George Leipnik, Kim Sutherland, Rebecca Hardwick, and Jeffrey Braithwaite

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Letter: long-term abdominal drains in refractory ascites-evolving concept of palliative care in decompensated cirrhosis. Authors' reply, Sumita Verma, Lucia Macken, Stephen Bremner, and David Sheridan

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Letter on “Protection by exclusion? The (lack of) inclusion of adults who lack capacity to consent to research in clinical trials in the UK”, Sarah Griffiths, Lorna Manger, Rebecca Chapman, Lauren Weston, Ian Sherriff, Cath Quinn, Paul Clarkson, Caroline Sutcliffe, Karen Davies, and Richard Byng

Lowering Mutant Huntingtin Levels and Toxicity: Autophagy-Endolysosome Pathways in Huntington's Disease, Shouqing Luo, Evelina Valionyte, Yi Yang, Sheridan L. Roberts, Jack Kelly, and Boxun Lu

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Maturo, A. and Moretti, V.Digital Health and the Gamification of Life, Bingley: Emerald Publishing2017. 176 pp (pbk) £60.00 (ebk) £43.19 ISBN 978‐1‐78754‐366‐9, J Tredinnick‐Rowe

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Measuring upper limb function in MS: Which existing patient reported outcomes are fit for purpose?, Jeremy Hobart, James Close, Kathryn Baines, and Laurie Burke

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Not so simple: the challenge of developing a non-motor symptoms app (NMS Assist) for people with Parkinson's (PwP), T Gorst, T Dominey, J Whipps, S Whipps, J Cooke, S Mullin, I Maramba, E Edwards, and C Carroll

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OCD Candidate Gene SLC1A1/EAAT3 Impacts Dopamine Neuron Firing and Behavioral Flexibility, M Chohan, J Kopelman, E Kramer, P Balsam, S Ahmari, and J Veenstra-Vanderweele

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Oxygenation of the critically ill in selected intensive care units in the UK: are we usual?, Benjamin Post, Edward Palmer, Steve Harris, Mervyn Singer, and Daniel Martin

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Physical activity and the prevention, reduction, and treatment of alcohol and other drug use across the lifespan (The PHASE review): A systematic review, T. P. Thompson, J. Horrell, A. H. Taylor, A. Wanner, K. Husk, Y. Wei, S. Creanor, R. Kandiyali, J. Neale, J. Sinclair, M. Nasser, and G. Wallace

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PROTOCOL: A comparison of the effectiveness of cognitive behavioural interventions based on delivery features for elevated symptoms of depression in adolescents, Gretchen J. Bjornstad, Shreya Sonthalia, Benjamin Rouse, Luke Timmons, Laura Whybra, and Nick Axford

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Randomised clinical trial: palliative long-term abdominal drains vs large-volume paracentesis in refractory ascites due to cirrhosis, Sumita Verma, Lucia Macken, Stephen Bremner, Heather Gage, Morro Touray, Peter Williams, David Crook, Louise Mason, Debbie Lambert, Catherine J. Evans, Max Cooper, Jean Timeyin, Shani Steer, Mark Austin, Nick Parnell, Sam J. Thomson, David Sheridan, Mark Wright, Peter Isaacs, and Ahmed Hashim

Randomised, double-blind, placebo controlled multi-centre study to assess the efficacy, tolerability and safety of Enterosgel® in the treatment of irritable bowel syndrome with diarrhoea (IBS-D) in adults, Anu Kemppinen, Carol Howell, Victoria Allgar, Matthew Dodd, John Gregson, Charles Knowles, John McLaughlin, Preeti Pandya, Peter Whorwell, Elena Markaryan, and Yan Yiannakou

Recurrent De Novo NAHR Reciprocal Duplications in the ATAD3 Gene Cluster Cause a Neurogenetic Trait with Perturbed Cholesterol and Mitochondrial Metabolism, Sian Ellard, Adam C. Gunning, Klaudia Strucinska, Oreja M Muñoz, Andrew Parrish, Richard Caswell, Karen L. Stals, Romina Durigon, Karina Durlacher-Betzer, Mitchell H. Cunningham, Christopher M. Grochowski, Julia Baptista, Carolyn Tysoe, Emma Baple, Nayana Lahiri, Tessa Homfray, Ingrid Scurr, Catherine Armstrong, John Dean, Pelayo U Fernandez, Aleck W.E. Jones, Robert W. Taylor, Vinod K. Misra, Wan Hee Yoon, Caroline F. Wright, James R. Lupski, Antonella Spinazzola, Tamar Harel, and Ian J. Holt

Recurrent TTN metatranscript‐only c.39974–11T>G splice variant associated with autosomal recessive arthrogryposis multiplex congenita and myopathy, Sandra T. Cooper, Samantha J. Bryen, Lisa J. Ewans, Jason Pinner, Suzanna C. MacLennan, Sandra Donkervoort, Diana Castro, Ana Töpf, Gina O'Grady, Beryl Cummings, Katherine R. Chao, Ben Weisburd, Laurent Francioli, Fathimath Faiz, Adam M. Bournazos, Ying Hu, Carla Grosmann, Denise M. Malicki, Helen Doyle, Nanna Witting, John Vissing, Kristl G. Claeys, Kathryn Urankar, A Beleza‐Meireles, Julia Baptista, Sian Ellard, Marco Savarese, Mridul Johari, Anna Vihola, and Bjarne Udd

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Reducing Bureaucracy in Clinical Research: A Call for Action, J Gribben, E Macintyre, P Sonneveld, J Doorduijn, and et al

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Reforming medical regulation: a qualitative study of the implementation of medical revalidation in England, using Normalization Process Theory, Abigail Tazzyman, Jane Ferguson, Alan Boyd, Marie Bryce, John Tredinnick-Rowe, Tristan Price, and Kieran Walshe

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Remimazolam for anaesthesia or sedation, J. Robert Sneyd and Ann E. Rigby-Jones

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Seizure and Sudden Unexpected Death in Epilepsy (SUDEP) characteristics in an urban UK intellectual disability service, Rohit Shankar, James J. Sun, Bhathika Perera, William Henley, and Samantha Ashby

Should we, can we, halt the rise in prescribing for pain and distress?, Richard Byng

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Smartphone-based optical assays in the food safety field, J. L.D. Nelis, A. S. Tsagkaris, M. J. Dillon, J. Hajslova, and C. T. Elliott

Systematic review of current randomised control trials in chronic subdural haematoma and proposal for an international collaborative approach, E Edlmann, D. C. Holl, H. F. Lingsma, J. Bartek, A. Bartley, J. Duerinck, T. S.R. Jensen, J. Soleman, N. C. Shanbhag, B. Indira Devi, T. Laeke, A. M. Rubiano, K. Fugleholm, der Veken J van, M. Tisell, P. J. Hutchinson, R. Dammers, and A. G. Kolias

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The cardiac output optimisation following liver transplant (COLT) trial: a feasibility randomised controlled trial, Brian Davidson, D Martin, Rahul Koti, Kurinchi Gurusamy, Louise Longworth, Jeshika Singh, Farid Froghi, F Soggiu, Susan Mallett, Nick Schofield, Linda Selves, Douglas Thorburn, Christine Eastgate, Helder Filipe, Margaret McNeil, Zacharias Anastasiou, Lasitha Abeysundara, Janice Baker, Elaine Burrell, Judith C. Leen, James Cuell, Kate Flavin, Kate Fryer, Vignesh Gopalan, Vivienne Hannon, Katherine, Horner, Sarah James, Rupinda Kaur, K Martin, Vivienne Hannon, N/A Katherine, N/A Horner, Sarah James, Rupinda Kaur, Rahul Koti, Louise Longworth, D Martin, K Martin, Susan Mallet, and Margaret McNeil

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The changing face of neurosurgery for the older person, Ellie Edlmann and Peter C. Whitfield

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The effectiveness of a therapeutic parenting program for children aged 6-11 years with behavioral or emotional difficulties: Results from a randomised controlled trial, Nick Axford, Gretchen Bjornstad, Justin Matthews, Sarah Heilmann, Anam Raja, Obioha C. Ukoumunne, Vashti Berry, Tom Wilkinson, Luke Timmons, Tim Hobbs, Tim Eames, Angeliki Kallitsoglou, Sarah Blower, and Georgina Warner

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The effectiveness of a therapeutic parenting program for children aged 6-11 years with behavioural or emotional difficulties: results from a randomized controlled trial, Nick Axford, Gretchen Bjornstad, Justin Matthews, Sarah Heilmann, Anam Raja, Obioha C. Ukoumunne, Vashti Berry, Tom Wilkinson, Luke Timmons, Tim Hobbs, Tim Eames, Angeliki Kallitsoglou, Sarah Blower, and Georgina Warner

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The effect of a dementia awareness class on changing dementia attitudes in adolescents, Nicolas Farina, Laura J. Hughes, Ellen Jones, Sahdia Parveen, Alys W. Griffiths, Kathleen Galvin, and Sube Banerjee

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The evidence for switching dibenzazepines in people with epilepsy, Rohit Shankar, Lance Watkins, Marie O'Dwyer, Katy Oak, Charlotte Lawthom, Melissa Maguire, and Rhys Thomas

The mediating effects of theory linked process measures on 12 month accelerometer recorded physical activity within the e-coacher RCT involving primary care exercise referral participants, A Taylor, A Streeter, W Ingram, J Lambert, S Dean, R Taylor, K Jolly, N Mutrie, and C Greaves

The neurology-psychiatry interface in epilepsy, Valerie Murphy, Brian Hallahan, Henry O' Connell, Brenda Wright, Brendan D. Kelly, Gautam Gulati, and Rohit Shankar

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Use of the Patient Health Questionnaire (PHQ-9) in Practice: Interactions between patients and physicians, Joseph Ford, Felicity Thomas, Richard Byng, and Rose McCabe

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Using a Delphi process to inform the design of disease modifying trials in Parkinson's disease, M Zeissler, R Windle, K McFarthing, K Raphael, G Rafaloff, and C Carroll

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What approaches to social prescribing work, for whom, and in what circumstances? A realist review, Kerryn Husk, Kelly Blockley, Rebecca Lovell, Alison Bethel, Iain Lang, Richard Byng, and Ruth Garside

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Women’s Digital Care Record ‘Accelerators’: Project Analysis Report, Arunangsu Chatterjee

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β-Cell Glucose Sensitivity determines hyperglycaemia in Polycystic Ovary Syndrome, J Tomlinson, A Mari, A Tura, K Bond, E Stenhouse, T Dew, RP Vincent, and J Pinkney

Submissions from 2019

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Professionalism and leadership in medical education: how do they differ and how are they related?, LJ Hardy and H Neve

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Remediating professionalism lapses in medical students and doctors: a systematic review, Nicola Brennan, Tristan Price, Julian Archer, and Joe Brett

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Why does the NHS struggle to adopt eHealth innovations? A review of macro, meso and micro factors, Sheena Asthana, Ray Jones, and Rod Sheaff

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Timing is key to providing modified assessments for students with specific learning difficulties, CP Gray and SA Burr

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Winter anthropology in Finland: Exploring ‘green care’ in low light, J Tredinnick-Rowe

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Distinct VIP and PACAP Functions in the Distal Nerve Stump During Peripheral Nerve Regeneration, Xin Peng Dun, Patricia K. Woodley, Qing Min, Yankun Li, Nina F. Mulvey, and David B. Parkinson

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Long-term follow-up of patients with mantle cell lymphoma (MCL) treated with the selective Bruton’s tyrosine kinase inhibitor tirabrutinib (GS/ONO-4059), SA Rule, G Cartron, C Fegan, F Morschhauser, and et al

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Analysis of Schwann Cell Migration and Axon Regeneration Following Nerve Injury in the Sciatic Nerve Bridge, B Chen, Q Chen, David B. Parkinson, and Xin Peng Dun

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Statistical analysis plan for the Dex-CSDH trial: a randomised, double-blind, placebo-controlled trial of a 2-week course of dexamethasone for adult patients with a symptomatic chronic subdural haematoma, Annabel Allison, Ellie Edlmann, Angelos G. Kolias, Carol Davis-Wilkie, Harry Mee, Eric P. Thelin, Carole Turner, Peter J. Hutchinson, and Simon Bond

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Bim contributes to the progression of Huntington's disease-associated phenotypes, Shouqing Luo, Sheridan L. Roberts, Tracey Evans, Yi Yang, Yuhua Fu, Robert W. Button, Rebecca J. Sipthorpe, Katrina Cowan, Evelina Valionyte, Oleg Anichtchik, Huiliang Li, and Boxun Lu

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Gender dysphoria: scientific oversight falling between responsible institutions should worry us all, Richard Byng and Susan Bewley

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Identifying undetected dementia in UK primary care patients: a retrospective case-control study comparing machine-learning and standard epidemiological approaches, E Ford, P Rooney, S Oliver, R Hoile, and et al

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COPD’s early origins in low-and-middle income countries: what are the implications of a false start?, EA Brakema, FA van Gemert, RMJJ van der Kleij, and et al

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Perioperative management of adult cadaveric and live donor renal transplantation in the UK: a survey of national practice, CM Morkane, J Fabes, NR Banga, PD Berry, and CJ Kirwan

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The Association between Supraphysiologic Arterial Oxygen Levels and Mortality in Critically Ill Patients. A Multicenter Observational Cohort Study, Edward Palmer, Benjamin Post, Roman Klapaukh, Giampiero Marra, Niall S. MacCallum, David Brealey, Ari Ercole, Andrew Jones, Simon Ashworth, Peter Watkinson, Richard Beale, Stephen J. Brett, J. Duncan Young, Claire Black, Aasiyah Rashan, Daniel Martin, Mervyn Singer, and Steve Harris

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Exosome release and neuropathology induced by α-synuclein: new insights into protective mechanisms of Drp1 inhibition, Mei Cui, Rebecca Z. Fan, Min Guo, Shouqing Luo, and Kim Tieu

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Randomised Controlled Trial Of The Effect Of Tai Chi On Postural Balance Of People With Dementia, Samuel R. Nyman, Wendy Ingram, Jeanette Sanders, PW Thomas, S Thomas, Michael Vassallo, James Raftery, Iram Bibi, and Yolanda Barrado-Martín

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Dynamic expression of Slit1–3 and Robo1–2 in the mouse peripheral nervous system after injury, B Chen, L Carr, and X-P Dun

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OncoSim and OncoWiki: an authentic learning approach to teaching cancer genomics, Priska Schoenborn, Richard Osborne, Nick Toms, Karen Johnstone, Chlöe Milsom, Reema Muneer, Michael A. Jarvis, and Robert Belshaw

Evaluation of nationwide referral pathways, investigation and treatment of suspected cauda equina syndrome in the United Kingdom, Daniel M. Fountain, Simon C.L. Davies, Julie Woodfield, Mohammed Kamel, Paulina Majewska, Ellie Edlmann, Aimun A.B. Jamjoom, Ingrid Hoeritzauer, Mueez Waqar, Dominic E. Mahoney, Dillon Vyas, Moritz W.J. Schramm, Georgios Solomou, Francesca E.C. Dawkes, Heidi K. Grant, Jonathan E. Attwood, Alexandros Boukas, Dominic J. Ballard, Emma Toman, Matthew I. Sanders, Beverly Cheserem, Saurabh Sinha, and Patrick Statham

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Broad Substrate-Specific Phosphorylation Events Are Associated With the Initial Stage of Plant Cell Wall Recognition in Neurospora crassa, J. Philipp Benz, Maria Augusta C. Horta, Nils Thieme, Yuqian Gao, Kristin E. Burnum-Johnson, Carrie D. Nicora, Marina A. Gritsenko, Mary S. Lipton, Karthikeyan Mohanraj, Leandro José de Assis, Liangcai Lin, Chaoguang Tian, Gerhard H. Braus, Katherine A. Borkovich, Monika Schmoll, Luis F. Larrondo, Areejit Samal, and Gustavo H. Goldman

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Allele-selective lowering of mutant HTT protein by HTT–LC3 linker compounds, Z Li, C Wang, Z Wang, Chenggang Zhu, J Li, Tian Sha, Lixiang Ma, Chao Gao, Yi Yang, Y Sun, J Wang, X Sun, C Lu, Marian Difiglia, Yanai Mei, C Ding, Shouqing Luo, Yongjun Dang, Y Ding, Yiyan Fei, and B Lu

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Exercise interventions for smoking cessation, Michael H. Ussher, Guy E.J. Faulkner, Kathryn Angus, Jamie Hartmann-Boyce, and Adrian H. Taylor

Bridging the gap of risk communication and management using the SUDEP and Seizure Safety Checklist, Rohit Shankar, Samantha Ashby, Brendan McLean, and Craig Newman

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A qualitative study on the impact of First Steps- a peer-led, educational intervention for people newly diagnosed with Parkinson’s Disease., Andrew Soundy, Johnny Collett, Sophie Lawrie, Shelly Coe, Helen Roberts, Michele Hu, Sally Bromley, Peter Harling, Alex Reed, Jan Coeberg, Camille Carroll, and Helen Dawes

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The impact of patient complaints and compliments on medical performance: a systematic review, R Baines, T Price, J Archer, and M Bryce

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Using interpersonal process recall to understand empowerment processes in a collaborative care intervention for people with a diagnosis of psychosis, Elina Baker, Ruth Gwernan-Jones, Nicky Britten, Cathy McCabe, Laura Gill, Richard Byng, and Linda Gask

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Simvastatin as a neuroprotective treatment for Parkinson's disease (PD STAT): Protocol for a double-blind, randomised, placebo-controlled futility study, Camille B. Carroll, Douglas Webb, Kara Nicola Stevens, Jane Vickery, Vicky Eyre, Susan Ball, Richard Wyse, Mike Webber, Andy Foggo, John Zajicek, Alan Whone, and Siobhan Creanor

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Durable response with single-agent acalabrutinib in patients with relapsed or refractory mantle cell lymphoma, M Wang, S Rule, PL Zinzani, and et al

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Theory protection in associative learning: humans maintain certain beliefs in a manner that violates prediction error, Peter M. Jones, Stuart G. Spicer, Chris J. Mitchell, and Andy J. Wills

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Evaluation of teamwork assessment tools for interprofessional simulation: a systematic review, T. C. Gale, E. L. Wooding, and V. Maynard

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Does a social prescribing ‘holistic’ link-worker for older people with complex, multi-morbidity improve well-being and frailty and reduce health and social care use and costs? A 12-month before and after evaluation, Sheena Asthana, Julian Elston, Felix Gradinger, Richard Byng, Caroline Lilley-Woolnough, Sue Wroe, and Helen Harman

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How Can Schools Support Parents' Engagement in their Children's Learning? Evidence from Research and Practice, N Axford, V Berry, J Lloyd, D Moore, M Rogers, A Hurst, K Blockley, H Durkin, and J Minton

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Classic axon guidance molecules control correct nerve bridge tissue formation and precise axon regeneration, Xin Peng Dun and David Parkinson

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Continuous Free Cortisol Profiles in Healthy Men - Validation of Microdialysis Method, R Bhake, GM Russell, Y Kershaw, K Stevens, and et al

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Improving epilepsy management with EpSMon: A Templar to highlight the multifaceted challenges of incorporating digital technologies into routine clinical practice, Rohit Shankar, Craig Newman, Samantha Ashby, and Brendan McLean

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‘Mind the gaps’: the accessibility and implementation of an effective depression relapse prevention programme in UK NHS services: learning from mindfulness-based cognitive therapy through a mixed-methods study, Willem Kuyken, Jo Rycroft-Malone, Felix Gradinger, Griffiths H Owen, Rob Anderson, Rebecca Susan Crane, Andy Gibson, and Stewart W. Mercer

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Exploring threshold concepts in population health, Hilary Neve, Eleanor J. Hothersall, and Veena Rodrigues

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Learning from significant medical events: a systematic review, TJ Price, R Baines, M Marshall, N Cameron, M Bryce, and J Archer

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A rare heterozygous TREM2 coding variant identified in familial clustering of dementia affects an intrinsically disordered protein region and function of TREM2, M Karsak, K Glebov, M Scheffold, and et al

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A rare heterozygous TREM2 coding variant identified in familial clustering of dementia affects an intrinsically disordered protein region and function of TREM2, M Karsak, K Glebov, M Scheffold, T Bajaj, A Kawalia, I Karaca, S Rading, J Kornhuber, O Peters, M Diez‐Fairen, L Frölich, M Hüll, J Wiltfang, M Scherer, S Riedel‐Heller, A Schneider, MT Heneka, K Fliessbach, A Sharaf, H Thiele, M Lennarz, F Jessen, W Maier, C Kubisch, Z Ignatova, P Nürnberg, P Pastor, J Walter, and A Ramirez

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Global health competencies in UK postgraduate medical training: a scoping review and curricular content analysis, Amitava Banerjee, Nader Al-Shakarchi, Lucy Obolensky, Sarah Walpole, and Harry Hemingway

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Evidence for similarity in symptoms and mechanism: the extra-pulmonary symptoms of severe asthma and polysymptomatic presentation of fibromyalgia, Michael E. Hyland, Rupert C. Jones, Joseph W. Lanario, Yinghui Wei, and Matthew Masoli