Browse research from the Peninsula Medical School.

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Submissions from 2024

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Knowledge, attitudes and practices of psychiatrists in India regarding sudden unexpected death in epilepsy (SUDEP) and seizure-related harm, Surobhi Chatterjee, Shivangini Singh, Sujita Kumar kar, and Rohit Shankar

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Does proactive care in care homes improve survival? A quality improvement project, David Attwood, Suzy Hope, Stuart Spicer, Adam Gordon, James Boorer, Wendy Ellis, Michelle Earley, Jillian Denovan, Gerard Hart, Maria Williams, Nicholas Burdett, and Melissa Lemon

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Awareness, attitudes, and beliefs of dementia in Indonesia, Nicolas Farina, Esra Hassan, Imelda Theresia, Fasihah Irfani Fitri, Ika Suswanti, Tara Puspitarini Sani, Sara Evans-Lacko, Sube Banerjee, and Yuda Turana

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Adult brain tumour research in 2024, Karin Purshouse, Helen J. Bulbeck, Alasdair G. Rooney, Karen E. Noble, Ross D. Carruthers, Gerard Thompson, Petra Hamerlik, Christina Yap, Kathreena M. Kurian, Sarah J. Jefferies, Juanita S. Lopez, Michael D. Jenkinson, C. Oliver Hanemann, and Lucy F. Stead

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Evaluating the clinical and cost-effectiveness of a conservative approach to oxygen therapy for invasively ventilated adults in intensive care, Daniel S. Martin, Tasnin Shahid, Doug W. Gould, Alvin Richards-Belle, James C. Doidge, Julie Camsooksai, Walton N. Charles, Miriam Davey, Amelia Francis Johnson, Roger M. Garrett, Michael P.W. Grocott, Joanne Jones, Lamprini Lampro, Lorna Miller, B. Ronan O’Driscoll, Anthony J. Rostron, Zia Sadique, Tamas Szakmany, Paul J. Young, Kathryn M. Rowan, David A. Harrison, and Paul R. Mouncey

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Dementia screening in rural Kenya: The prevalence and impact of screening positive for dementia, C Musyimi, D Ndetei, L Muyela, J Masila, and N Farina

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The barriers to and facilitators of implementing early mobilisation for patients with delirium on intensive care units, Jacqueline Bennion, Christopher Manning, Stephanie K. Mansell, Roger Garrett, and Daniel Martin

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Perampanel for the treatment of epilepsy with genetic aetiology, Norman Delanty, Rajiv Mohanraj, Rohit Shankar, Tim Wehner, Linda J. Stephen, Wendyl D'Souza, Sheri Cappucci, Rob McMurray, Ricardo Sainz-Fuertes, and Vicente Villanueva

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Pharmacological management of fragile X syndrome, Lance V. Watkins, Seungyoun Moon, Lisa Burrows, Samuel Tromans, Julian Barwell, and Rohit Shankar

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Mental Imagery to Reduce Alcohol-related harm in patients with alcohol use disorder and alcohol-related liver damaGE, Ashwin Dhanda, Jackie Andrade, Hannah Allende, Victoria Allgar, Matthew Bailey, Lynne Callaghan, Laura Cocking, Elizabeth Goodwin, Annie Hawton, Christopher Hayward, Ben Hudson, Wendy Ingram, Alison Jeffery, Angela King, Victoria Lavers, Joe Lomax, C Anne McCune, Crispin Musicha, Richard Parker, Christopher Rollinson, Jonny Wilks, and E Siobhan Creanor

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Transition Hub for Children Looked After: Feasibility and Pilot Study Report, Nick Axford, Vashti Berry, Lynne Callaghan, Kate Allen, Lucy Cartwright, Rebecca S Bates, Sarah Rybczynska-Bunt, Jane Horrell, and Kristin Liabo

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Deep Learning Detection of Aneurysm Clips for Magnetic Resonance Imaging Safety, M Courtman, D Kim, H Wit, H Wang, L Sun, E Ifeachor, S Mullin, and M Thurston

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Exploring the relationships between psychological variables and loot box engagement, part 2: exploratory analyses of complex relationships, Stuart Gordon Spicer, James Close, Laura Louise Nicklin, Maria Uther, Ben Whalley, Chris Fullwood, Jonathan Parke, J Lloyd, and H Lloyd

Submissions from 2023

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Exploring basic science knowledge retention within a cohort of undergraduate medical students in the United Kingdom: A longitudinal study, Idrees Zafar, John Chilton, James Edwards, Helen Watson, and Daniel Zahra

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Modifiable Risk Factors for Dementia in Indonesia: Results from STRiDE Project, Fitri F. Irfani, Nicolas Farina, Yuda Turana, Imelda Theresia, Tara Puspitarini Sani, Ika Suswanti, and Sube Banerjee

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Embedding Patient Input in Outcome Measures for Long‐Term Disease‐Modifying Parkinson Disease Trials, C Gonzalez‐Robles, Michèle Bartlett, Matthew Burnell, Caroline S. Clarke, Shlomi Haar, Michele T. Hu, Brook Huxford, Ashwani Jha, Michael Lawton, Alastair Noyce, Paola Piccini, Kuhan Pushparatnam, Lynn Rochester, Carroll Siu, Wamelen D van, CH Williams‐Gray, Marie Louise Zeissler, Henrik Zetterberg, Camille B. Carroll, Thomas Foltynie, Rimona S. Weil, and Anette Schrag

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Real world impact of Christmas BMJ research, Stuart Spicer, Graham Johnson, Andrew Tabner, Jill Matthews, and Kerryn Husk

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A novel patient-derived meningioma spheroid model as a tool to study and treat epithelial-to-mesenchymal transition (EMT) in meningiomas, de Weijer LL van, Emanuela Ercolano, Ting Zhang, Maryam Shah, Matthew C. Banton, Juri Na, Claire L. Adams, David Hilton, Kathreena M. Kurian, and C. Oliver Hanemann

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The Dementia Severity Rating Scale: a potential community screening tool for dementia in low- and middle-income countries, Yuda Turana, Nicolas Farina, Imelda Theresia, Fasihah Irfani Fitri, Ika Suswanti, Roxanne Jacobs, Marguerite Schneider, Tara Puspitarini Sani, Adelina Comas-Herrera, Emiliano Albanese, Ishtar Govia, Cleusa P. Ferri, Martin Knapp, and Sube Banerjee

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Audit and feedback to reduce unwarranted clinical variation at scale: a realist study of implementation strategy mechanisms, Mitchell Sarkies, Emilie Francis-Auton, Janet Long, Natalie Roberts, Johanna Westbrook, Jean Frederic Levesque, Diane E. Watson, Rebecca Hardwick, Kim Sutherland, Gary Disher, Peter Hibbert, and Jeffrey Braithwaite

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Investigating trial design variability in trials of disease-modifying therapies in Parkinson’s disease: a scoping review protocol, Marie Louise Zeissler, Timothy Boey, Danny Chapman, Gary Rafaloff, Thea Dominey, Karen G. Raphael, Susan Buff, Hari Venkatesh Pai, Emma King, Paul Sharpe, Fintan O’Brien, and Camille B. Carroll

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Early computed tomography coronary angiography and preventative treatment in patients with suspected acute coronary syndrome: A secondary analysis of the RAPID-CTCA trial, Kang Ling Wang, Mohammed N. Meah, Anda Bularga, Katherine Oatey, Rachel O'Brien, Jason E. Smith, Nick Curzen, Attila Kardos, Liza Keating, Dirk Felmeden, Robert F. Storey, Steve Goodacre, Carl Roobottom, David E. Newby, and Alasdair J. Gray

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Exploring the relationships between psychological variables and loot box engagement, part 1: pre-registered hypotheses, James Close, Stuart Gordon Spicer, Laura Louise Nicklin, Maria Uther, Ben Whalley, Chris Fullwood, Jonathan Parke, J Lloyd, and H Lloyd

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National study of NAFLD management identifies variation in delivery of care in the UK between 2019 to 2022, Wenhao Li, David Sheridan, Stuart McPherson, William Alazawi, Kush Abeysekera, Tom Marjot, Paul Brennan, Sara Mahgoub, Tessa Cacciottolo, Theresa Hydes, Tim Hardy, Gio McGinty, Oliver Tavabie, Jennifer Cathcart, Chirantha Premathilaka, Ashis Mukhopadhya, Arshiya Bhat, Shahnaz Begum, Bashar Abushaban, Meha Bhuva, Sophie Sinclair, Damien Leith, Cullen McCulloch, Joanna Leithead, Richard Fox, MH Shah, Eugene Campbell, Edward Brown, Dina Mansour, F Shah, Michael Allison, Jonathan Chan, Victoria Roberts, Gautham Appanna, Mandour Omer Mandour, Georgina Slee, Vicki Wong, Sreelakshmi Kotha, Katrina Pekarska, Richard Parker, Cyril Sieberhagen, Thomas Ngan, Esra Asilmaz, Hamish Miller, Jeremy Cobbold, Dom Crocombe, Manolis Tsochatzis, Sudeep Tanwar, Aruna Dias, Gurmit Singh, S Agrawal, P Chhabra, A Gurung, R Veettil, RD Abeles, D Chatterjee, M Carbonell, Z Mohamed, A El-Sayed, A Johnson, Damien Leith, S Barclay, K Kelly, J Munonye, D Coates, O Bamidele, T Johnston, D Samuel, B Ball, R Arscott-Samuel, P Hams, M Armstrong, A Elkhol, K Shailesh, V Bains, P Manousou, T Gupta, S Than, E Unitt, V Gordon, A Wakefield, S Gilchrist, I Cozma, S Saeed, S Umrani, and K Olsen

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Patient safety in remote primary care encounters: multimethod qualitative study combining Safety I and Safety II analysis, Rebecca Payne, Aileen Clarke, Nadia Swann, Dael J van, Natassia Brenman, Rebecca Rosen, Adam Mackridge, Lucy Moore, Asli Kalin, Emma Ladds, Nina Hemmings, Sarah Rybczynska-Bunt, Stuart Faulkner, Isabel Hanson, Sophie Spitters, Sietse Wieringa, Francesca H. Dakin, Sara E. Shaw, Joseph Wherton, Richard Byng, Laiba Husain, and Trisha Greenhalgh

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Identification of druggable regulators of cell secretion via a kinome-wide screen and high-throughput immunomagnetic cell sorting, Mahmoud Labib

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An International Multi-Stakeholder Delphi Survey Study on the Design of Disease Modifying Parkinson’s Disease Trials, Marie Louise Zeissler, Kevin McFarthing, Karen G. Raphael, Gary Rafaloff, Richard Windle, and Camille B. Carroll

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A pragmatic randomized controlled exploratory trial of the effectiveness of Eye Movement Desensitization and Reprocessing therapy for psychotic disorder, Simon Marlow, Richard Laugharne, Jon Allard, Paul Bassett, Stefan Priebe, Joanne Ledger, Jacqueline Kerr, Deborah Priest, Alje Vanhoorn, Cailin Boland, and Rohit Shankar

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A programme evaluation of ‘First Steps’: A peer-conceived, developed and led self-management intervention for people after a Parkinson's diagnosis, Johnny Collett, Sophie Lawrie, Sally Bromley, Peter Harling, Alex Reed, Natasha Brusco, Shelly Coe, Jan Coebergh, Camille Carroll, Helen C. Roberts, Michele T. Hu, and Helen Dawes

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The potential for medicinal cannabis to help manage challenging behaviour in people with intellectual disability: A perspective review, Laura Korb, Samuel Tromans, Bhathika Perera, Nagina Khan, Lisa Burrows, Richard Laugharne, Angela Hassiotis, Victoria Allgar, Daryl Efron, Ian Maidment, and Rohit Shankar

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Exploring recent patterns of migration of doctors to the United Kingdom: a mixed-methods study, N. Brennan, N. Langdon, T. Gale, N. Humphries, A. Knapton, and M. Bryce

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EVALUATING THE MANAGEMENT OF CHRONIC PELVIC GIRDLE PAIN FOLLOWING PREGNANCY (EMAPP): A RANDOMISED CONTROLLED FEASIBILITY TRIAL, B Halliday, S Chatfield, L Cameron, J Hosking, J Shawe, A hawston, C Hayward, K Carter, and J Freeman

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A modular, deep learning-based holistic intent sensing system tested with Parkinson’s disease patients and controls, Joseph Russell, Jemma Inches, Camille B. Carroll, and Jeroen H.M. Bergmann

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Gelation of cytoplasmic expanded CAG RNA repeats suppresses global protein synthesis, Yuyin Pan, J Lu, Xinran Feng, S Lu, Y Yang, G Yang, Shudan Tan, Liang Wang, Pilong Li, Shouqing Luo, and B Lu

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Phenotypic effect of GBA1 variants in individuals with and without Parkinson's disease: The RAPSODI study, Marco Toffoli, Harneek Chohan, Stephen Mullin, Aaron Jesuthasan, Selen Yalkic, Sofia Koletsi, Elisa Menozzi, Soraya Rahall, Naomi Limbachiya, Nadine Loefflad, Abigail Higgins, Jonathan Bestwick, Sara Lucas-Del-Pozo, Federico Fierli, Audrey Farbos, Roxana Mezabrovschi, Chiao Lee-Yin, Anette Schrag, David Moreno-Martinez, Derralynn Hughes, Alastair Noyce, Kevin Colclough, Aaron R. Jeffries, Christos Proukakis, and Anthony H.V. Schapira

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The effect of conservative oxygen therapy on mortality in adult critically ill patients: A systematic review and meta-analysis of randomised controlled trials, Daniel S. Martin, Helen T. Mckenna, Kathryn M. Rowan, Doug W. Gould, Paul R. Mouncey, Michael P.W. Grocott, and David A. Harrison

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JAK3 Inhibition Regulates Stemness and Thereby Controls Glioblastoma Pathogenesis, William Smedley and Amiya Patra

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Open‐label, clinical trial extension: Two‐year safety and efficacy results of seladelpar in patients with primary biliary cholangitis, Marlyn J. Mayo, John M. Vierling, Christopher L. Bowlus, Cynthia Levy, Gideon M. Hirschfield, Guy W. Neff, Michael R. Galambos, Stuart C. Gordon, Brian B. Borg, Stephen A. Harrison, Paul J. Thuluvath, Aparna Goel, Mitchell L. Shiffman, Mark G. Swain, David E.J. Jones, Palak Trivedi, Andreas E. Kremer, Richard J. Aspinall, David A. Sheridan, Yvonne Dörffel, Ke Yang, Yun Jung Choi, and Charles A. McWherter

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Engagement with engager: what factors are associated with attendance in a complex intervention for men with common mental health problems, near to and after release from prison, Charlotte Lennox, Stuart G. Spicer, Sarah Leonard, and Richard Byng

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Medical students' perceptions of a novel international adaptive progress test, Jolanta Kisielewska, Paul Millin, Neil Rice, Jose Miguel Pego, Steven Burr, Michal Nowakowski, and Thomas Gale

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A narrative review of adaptive testing and its application to medical education., S Burr, T Gale, J Kisielewska, P Millin, JM Pêgo, G Pinter, I Robinson, and D Zahra

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Autistic adults’ experiences of managing wellbeing and implications for social prescribing, Charlotte Featherstone, Richard Sharpe, Nick Axford, Sheena Asthana, and Kerryn Husk

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Correction: Continuous Subcutaneous Foslevodopa/Foscarbidopa in Parkinson’s Disease: Safety and Efficacy Results From a 12-Month, Single-Arm, Open-Label, Phase 3 Study, Jason Aldred, Eric Freire-Alvarez, Alexander V. Amelin, Angelo Antonini, Bruno Bergmans, Filip Bergquist, Manon Bouchard, Kumar Budur, Camille Carroll, K. Ray Chaudhuri, Susan R. Criswell, Erik H. Danielsen, Florin Gandor, Jia Jia, Thomas E. Kimber, Hideki Mochizuki, Weining Z. Robieson, Amy M. Spiegel, David G. Standaert, Saritha Talapala, Maurizio F. Facheris, and Victor S.C. Fung

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Adding web-based support to exercise referral schemes improves symptoms of depression in people with elevated depressive symptoms: A secondary analysis of the e-coachER randomised controlled trial, Jeffrey Lambert, Adrian Taylor, Adam Streeter, Colin Greaves, Wendy M. Ingram, Sarah Dean, Kate Jolly, Nanette Mutrie, Lisa Price, and John Campbell

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A pragmatic, multicentre, double-blind, placebo-controlled randomised trial to assess the safety, clinical and cost-effectiveness of mirtazapine and carbamazepine in people with Alzheimer’s disease and agitated behaviours: the HTA-SYMBAD trial, Sube Banerjee, Nicolas Farina, Catherine Henderson, Juliet High, Susan Stirling, Lee Shepstone, Julia Fountain, Clive Ballard, Peter Bentham, Alistair Burns, Chris Fox, Paul Francis, Robert Howard, Martin Knapp, Iracema Leroi, Gill Livingston, Ramin Nilforooshan, Shirley Nurock, John O’brien, Annabel Price, Alan J. Thomas, Ann Marie Swart, Tanya Telling, and Naji Tabet

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Genome-wide Analysis of Motor Progression in Parkinson Disease, Carrasco A. Martínez, R Real, M Lawton, Reynolds R Hertfelder, M Tan, L Wu, N Williams, C Carroll, J-C Corvol, M Hu, D Grosset, J Hardy, M Ryten, Y Ben-Shlomo, M Shoai, and HR Morris

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Quality standards for the management of alcohol-related liver disease: consensus recommendations from the British Association for the Study of the Liver and British Society of Gastroenterology ARLD special interest group, Richard Parker, Michael Allison, Seonaid Anderson, Richard Aspinall, Sara Bardell, Vikram Bains, Ryan Buchanan, Lynsey Corless, Ian Davidson, Pauline Dundas, Jeff Fernandez, Ewan Forrest, Erica Forster, Dennis Freshwater, Ruth Gailer, Robert Goldin, Vanessa Hebditch, Steve Hood, Arron Jones, Victoria Lavers, Deborah Lindsay, James Maurice, Joanne McDonagh, Sarah Morgan, Tania Nurun, Christopher Oldroyd, Elizabeth Oxley, Sally Pannifex, Graham Parsons, Thomas Phillips, Nicole Rainford, Neil Rajoriya, Paul Richardson, J. Ryan, Joanne Sayer, Mandy Smith, Ankur Srivastava, Emma Stennett, Jennifer Towey, Roya Vaziri, Ian Webzell, Andrew Wellstead, Ashwin Dhanda, and Steven Masson

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Transporting an evidence-based program to a new country: a narrative description and analysis of pre-implementation adaptation, Finlay Green, Nick Axford, Ntale Eastmond, Vashti Berry, Julia Mannes, Kate Allen, Lynne Callaghan, and Tim Hobbs

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A magneto-activated nanoscale cytometry platform for molecular profiling of small extracellular vesicles, Kangfu Chen, Bill T.V. Duong, Sharif U. Ahmed, Piriththiv Dhavarasa, Z Wang, Mahmoud Labib, Connor Flynn, Jingya Xu, Yi Y. Zhang, H Wang, Xiaolong Yang, Jagotamoy Das, Hossein Zargartalebi, Yuan Ma, and Shana O. Kelley

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Integration and Evaluation of a Community-Level Dementia Screening Program in Kenya (DEM-SKY): A Protocol, Christine Musyimi, David Ndetei, Levi Abisai Muyela, Joe Masila, Elizabeth Mutunga, and Nicolas Farina

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Outcome Measures for Disease-Modifying Trials in Parkinson’s Disease: Consensus Paper by the EJS ACT-PD Multi-Arm Multi-Stage Trial Initiative, Cristina Gonzalez-Robles, Rimona S. Weil, Wamelen D van, Michèle Bartlett, Matthew Burnell, Caroline S. Clarke, Michele T. Hu, Brook Huxford, Ashwani Jha, Christian Lambert, Michael Lawton, Georgia Mills, Alastair Noyce, Paola Piccini, Kuhan Pushparatnam, Lynn Rochester, Carroll Siu, Caroline H. Williams-Gray, Marie Louise Zeissler, Henrik Zetterberg, Camille B. Carroll, Thomas Foltynie, and Anette Schrag

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How Safety Culture Surveys Influence the Quality and Safety of Healthcare Organisations, RM Bethune, S Ball, N Doran, M Harris, A Medina-Lara, M Fornasiero, M Hill, I Lang, J McGregor-Harper, and R Sheaff

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Recommendations from Diabetes UK's 2022 diabetes and physical activity workshop, Anna Morris, Chris Bright, Matthew Cocks, Neil Gibson, Louise Goff, Colin Greaves, Simon Griffin, Ben Jane, Florence Kinnafick, Paul Robb, Michelle Roberts, David Salman, John Saxton, Adrian Taylor, Daniel West, Thomas Yates, Rob C. Andrews, and Jason M.R. Gill

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Review of the validity of DOPS as an assessment tool for the procedural skills of surgical trainees, M. Rela and T. Price

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Genetic meta-analysis of levodopa induced dyskinesia in Parkinson’s disease, Alejandro Martinez-Carrasco, Raquel Real, Michael Lawton, Hirotaka Iwaki, Manuela M.X. Tan, Lesley Wu, Nigel M. Williams, Camille Carroll, Michele T.M. Hu, Donald G. Grosset, John Hardy, Mina Ryten, Tom Foltynie, Yoav Ben-Shlomo, Maryam Shoai, and Huw R. Morris

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The development and validation of the Discrimination and Stigma Scale Ultra Short for People Living with Dementia, Jem Bhatt, Elaine Brohan, Drew Blasco, Déborah Oliveira, Ioannis Bakolis, Adelina Comas-Herrera, Francesco D'Amico, Nicolas Farina, Martin Knapp, Madeleine Stevens, Graham Thornicroft, Emma Wilson, Maximilian Salcher-Konrad, Lawrence H. Yang, and Sara Evans-Lacko

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The role of digital transformation in addressing health inequalities in coastal communities: barriers and enablers, Sheena Asthana and Samantha Prime

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Continuous Subcutaneous Foslevodopa/Foscarbidopa in Parkinson’s Disease: Safety and Efficacy Results From a 12-Month, Single-Arm, Open-Label, Phase 3 Study, Jason Aldred, Eric Freire-Alvarez, Alexander V. Amelin, Angelo Antonini, Bruno Bergmans, Filip Bergquist, Manon Bouchard, Kumar Budur, Camille Carroll, K. Ray Chaudhuri, Susan R. Criswell, Erik H. Danielsen, Florin Gandor, Jia Jia, Thomas E. Kimber, Hideki Mochizuki, Weining Z. Robieson, Amy M. Spiegel, David G. Standaert, Saritha Talapala, Maurizio F. Facheris, and Victor S.C. Fung

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Practical diagnosis of cirrhosis in non-alcoholic fatty liver disease using currently available non-invasive fibrosis tests, J Boursier, Marine Roux, Charlotte Costentin, Julien Chaigneau, Céline Fournier-Poizat, Aldo Trylesinski, CM Canivet, Sophie Michalak, Bail B Le, Valérie Paradis, Pierre Bedossa, Nathalie Sturm, Ledinghen V de, Justine Barthelon, J Boursier, Paul Cales, C Canivet, Thomas Decaens, Adèle Delamarre, Paul Hermabessiere, Marie Irles-Depé, Ledinghen V de, Marie Noelle Hilleret, Isabelle Fouchard-Hubert, Adrien Lannes, Bail B Le, Valérie Moal, Fréderic Oberti, Michael Allison, Quentin M. Anstee, Jeremy F. Cobbold, Jonathan J. Deeks, Peter J. Eddowes, Indra N. Guha, David Sheridan, Emmanuel Tsochatzis, and Philip N. Newsome

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A pilot examination of the validity of stylus and finger drawing on visuomotor-mediated tests on ACEmobile, Rupert Noad, Craig Newman, Jade Chynoweth, Jacob Mayers, Stephen Hall, and Donnchadh Murphy

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How is transition to medical practice shaped by a novel transitional role? A mixed-methods study, Bryan Burford, Karen Mattick, Daniele Carrieri, Anna Goulding, Thomas Gale, Nicola Brennan, and Gillian Vance

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From the individual to the organisation: Transferring learning from Global Health Projects into Organisational Change, A Inman, L Spowart, L Hardy, and M Dillon

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Commodification and healthcare in the third sector in England: from gift to commodity – and back?, Rod Sheaff, Angela Ellis-Paine, Mark Exworthy, Rebecca Hardwick, and Chris Q. Smith

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A Qualitative Exploration of Patient and Staff Experiences of the Receipt and Delivery of Specialist Weight Management Services in the UK, Ross Watkins, Dawn Swancutt, Mia Alexander, Shokraneh Moghadam, Steve Perry, Sarah Dean, Rod Sheaff, Jonathan Pinkney, Mark Tarrant, and Jenny Lloyd

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Liquidity and uncertainty: digital adaptation of a complex intervention for people with severe mental illness during the COVID-19 lockdown, J Frost, C Hobson-Merrett, L Gask, M Clark, V Pinfold, H Plappert, S Reilly, J Gibson, D Richards, R Denyer, and R Byng

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Do clinical trials prepare to fail by failing to prepare? An examination of MS trials and recommendations for patient-reported outcome measure selection, Jeremy Hobart, Tanuja Chitnis, Jiwon Oh, Laurie Burke, Miriam King, Pamela Vo, Jo Vandercappellen, and Andrew Lloyd

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How to … define clinical education research terminology: A glossary, Gabrielle M. Finn, Ben Charmer, Oliver E. Burton, Aqua Asif, Matthew H.V. Byrne, Nicola Brennan, and Megan E.L. Brown

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Clinical features and outcomes of hospitalised patients with COVID-19 and Parkinsonian disorders: A multicentre UK-based study, Lexy Sorrell, Valentina Leta, Anton Barnett, Kara Stevens, Angela King, Jemma Inches, Christopher Kobylecki, Richard Walker, KR Chaudhuri, Hannah Martin, Jane Rideout, JR Sneyd, Sarah Campbell, and Camille Carroll

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Health promotion and public health, Tamar Avades and Ashwin Dhanda

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Factors associated with dementia attitudes in an adolescent cohort: structural equation modelling, Esra Hassan, Ben Hicks, Naji Tabet, and Nicolas Farina

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Commentary on “Why am I still in hospital? Evaluation of delayed discharges from two learning disability assessment and treatment units in England”, Rohit Shankar

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Efficient Delivery of Biological Cargos into Primary Cells by Electrodeposited Nanoneedles via Cell-Cycle-Dependent Endocytosis, Z Wang, H Wang, Sichun Lin, Mahmoud Labib, Sharif Ahmed, Jagotamoy Das, Stephane Angers, Edward H. Sargent, and Shana O. Kelley

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Perioperative redox changes in patients undergoing hepato-pancreatico-biliary cancer surgery, JL Stevens, HT McKenna, H Filipe, L Lau, BO Fernandez, AJ Murray, M Feelisch, and DS Martin

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Giant worm-shaped ESCRT scaffolds surround actin-independent integrin clusters, Femmy C. Stempels, Muwei Jiang, Harry M. Warner, Magda Lena Moser, Maaike H. Janssens, Sjors Maassen, Iris H. Nelen, Boer R de, William F. Jiemy, David Knight, Julian Selley, Ronan O’cualain, Maksim V. Baranov, Thomas C.Q. Burgers, Roberto Sansevrino, Dragomir Milovanovic, Peter Heeringa, Matthew C. Jones, Rifka Vlijm, Beest M ter, and den Bogaart G van

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Towards a multi-arm multi-stage platform trial of disease modifying approaches in Parkinson’s disease, Tom Foltynie, Sonia Gandhi, Cristina Gonzalez-Robles, Marie Louise Zeissler, Georgia Mills, Roger Barker, James Carpenter, Anette Schrag, Anthony Schapira, Oliver Bandmann, Stephen Mullin, Joy Duffen, Kevin McFarthing, Jeremy Chataway, Mahesh Parmar, Camille Carroll, Yoav Ben Shlomo, Mark Edwards, Alan Whone, Carl Counsell, Caroline Clarke, Matthew Burnell, Dorothy Salathiel, Sue Whipps, Anna Jewell, Tom Barber, Rimona Weil, Caroline Williams Gray, Michele Hu, Lynn Rochester, Paola Piccini, Henrik Zetterberg, Alastair Noyce, Ray Chaudhuri, Michael Lawton, Ashwani Jha, Carroll Siu, Michèle Bartlett, Wamelen D van, Simon Stott, George Tofaris, Esther Sammler, Heather Mortiboys, Li Wei, Alan Wong, Susan Duty, David Dexter, Paula Scurfield, Edwin Jabbari, Huw Morris, D Breen, C Lambert, P Korlipara, M Silverdale, K Bhatia, A Yarnall, R Khengar, H Collins, F Hudson, G Baxendale, R Croucher, S Bartolomeur-Pires, J Allison, A Morgan, S Wonnacott, D Athauda, E Henderson, S Clegg, K Matthews, E Deeson, L Miller, J Handley, H Matthews, A Batla, N Bakshi, B Port, R Ellis-Doyle, SL Collins, J Rudiger, R Chapman, J Cedarbaum, A Lang, B Fiske, R Wyse, A Boxer, D Wilson, JC Corvol, and J Harris

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Comprehensive measurement of the prevalence of dementia in low- and middle-income countries: STRiDE methodology and its application in Indonesia and South Africa, Nicolas Farina, Roxanne Jacobs, Yuda Turana, Fasihah Irfani Fitri, Marguerite Schneider, Imelda Theresia, Sumaiyah Docrat, Tara Puspitarini Sani, Lydia Augustina, Emiliano Albanese, Adelina Comas-Herrera, Toit P Du, Cleusa P. Ferri, Ishtar Govia, Aliaa Ibnidris, Martin Knapp, and Sube Banerjee

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Patient-reported outcomes in multiple sclerosis: a prospective registry cohort study, Annalaura Lerede, Jeff Rodgers, Rod M. Middleton, Adam Hampshire, Richard Nicholas, Alasdair Coles, Jeremy Chataway, Martin Duddy, Hedley Emsley, H Ford, Leonora Fisniku, Ian Galea, Timothy Harrower, Jeremy Hobart, Huseyin Huseyin, Christopher M. Kipps, Monica Marta, Gavin V. McDonnell, Brendan McLean, Owen Pearson, David Rog, Klaus Schmierer, Basil Sharrack, Agne Straukiene, and DV Ford

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Transition theory and the emotional journey to medical educator identity: A qualitative interview study, J Browne and T Collett

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Conversation Analysis of Clients’ Active Resistance to Veterinarians’ Proposals for Long-Term Dietary Change in Companion Animal Practice in Ontario, Canada, Hannah Wheat, Clare MacMartin, and Jason B. Coe

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A blended future? A cross‐sectional study demonstrating the impacts of the COVID‐19 pandemic on student experiences of well‐being, teaching and learning, John K. Chilton, Sally Hanks, and Helen R. Watson

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Measures Determining Dementia-Related Attitudes in Adolescents: A Scoping Review, Esra Hassan, Ben Hicks, Naji Tabet, and Nicolas Farina

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Practitioners’ Ability to Remotely Develop Understanding for Personalised Care and Support Planning: a Thematic Analysis of Multiple Data Sources from the Feasibility Phase of the Dementia PersonAlised Care Team (D-PACT) Intervention., H Wheat

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Measuring Fatigue in Multiple Sclerosis: There may be Trouble Ahead, James Close, Jo Vandercappellen, Miriam King, and Jeremy Hobart

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Using a Stages Model to Reveal the Politics in the Health Policy Process Comment on "Modelling the Health Policy Process: One Size Fits All or Horses for Courses?", Rod Sheaff

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Dementia in South Africa: A Situational Analysis, Roxanne Jacobs, Marguerite Schneider, Nicolas Farina, Toit P du, Sumaiyah Docrat, Adelina Comas-Herrera, and Martin Knapp

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Constraints and affordances for UK doctors‐in‐training to exercise agency: A dialogical analysis, Karen Mattick, Anna Goulding, Daniele Carrieri, Nicola Brennan, Bryan Burford, Gillian Vance, and Tim Dornan

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A high-dimensional microfluidic approach for selection of aptamers with programmable binding affinities, Dingran Chang, Z Wang, Connor D. Flynn, Alam Mahmud, Mahmoud Labib, H Wang, Armin Geraili, Xiangling Li, Jiaqi Zhang, Edward H. Sargent, and Shana O. Kelley

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Estimating the number of people living with dementia at different stages of the condition in India: A Delphi process, Nicolas Farina, Jayeeta Rajagopalan, Suvarna Alladi, Aliaa Ibnidris, Cleusa P. Ferri, Martin Knapp, and Adelina Comas-Herrera

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Dietary Patterns and Practices and Leucocyte Telomere Length: Findings from the UK Biobank, Vasiliki Bountziouka, Christopher P. Nelson, Qingning Wang, Crispin Musicha, Veryan Codd, and Nilesh J. Samani

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Drugless and radiographer led: the start of a new era for CT coronary angiography, Gareth Morgan-Hughes, Rebecca Mcnally, Christopher Gibbs Gibbs, Stelios Iacovides, Prabesh Kirat-Rai, Nang Thiriphoo, Alison Powell, Colin Stuckey, Ross Thorpe, Louisa Mayo, and Carl Roobottom

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Guiding principles for effective collaborative implementation strategies for multisite hospital improvement initiatives: a mixed-method realist evaluation of collaborative strategies used in four multisite initiatives at public hospitals in New South Wales, Australia, Janet C. Long, Mitchell N. Sarkies, Emilie Francis-Auton, Natalie Roberts, Rebecca Hardwick, Hoa Mi Nguyen, Jean Frederic Levesque, Diane E. Watson, Johanna Westbrook, Peter D. Hibbert, Frances Rapport, and Jeffrey Braithwaite

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Strategies are needed to support people with alcohol use disorder and alcohol-related liver disease to take part in randomised clinical trials: results from the MIRAGE pilot trial of functional imagery training, A Dhanda, V Allgar, J Andrade, L Callaghan, B Hudson, W Ingram, A King, V Lavers, J Lomax, A McCune, C Musicha, R Parker, C Rollinson, and S Creanor

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Randomized, controlled clinical trial of the DIALIVE liver dialysis device versus standard of care in patients with acute-on- chronic liver failure, Banwari Agarwal, Rafael Bañares Cañizares, Faouzi Saliba, Maria Pilar Ballester, Dana Rodica Tomescu, Daniel Martin, Vanessa Stadlbauer, Gavin Wright, Mohammed Sheikh, Carrie Morgan, Carlos Alzola, Phillip Lavin, Daniel Green, Rahul Kumar, Sophie Caroline Sacleux, Gernot Schilcher, Sebastian Koball, Andrada Tudor, Jaak Minten, Gema Domenech, Juan Jose Aragones, Karl Oettl, Margret Paar, Katja Waterstradt, Stefanie M. Bode-Boger, Luis Ibáñez-Samaniego, Amir Gander, Carolina Ramos, Alexandru Chivu, Jan Stange, Georg Lamprecht, Moises Sanchez, Rajeshwar P. Mookerjee, Andrew Davenport, Nathan Davies, Marco Pavesi, Fausto Andreola, Agustin Albillos, Jeremy Cordingley, Hartmut Schmidt, Juan Antonio Carbonell-Asins, Vicente Arroyo, Javier Fernandez, Steffen Mitzner, and Rajiv Jalan

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SARS-CoV-2 infection causes periodontal fibrotic pathogenesis through deregulating mitochondrial beta-oxidation, Yan Gao, Wai Ling Kok, Vikram Sharma, Charlotte Sara Illsley, Sally Hanks, Christopher Tredwin, and Bing Hu

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The role of the voluntary, community and social enterprise sector in Early Help: Critical reflections from embedded social care research, T El‐Hoss, Felicity Thomas, Felix Gradinger, and Susanne Hughes

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Loneliness and social networks of older adults in rural communities: a narrative synthesis systematic review, Basharat Hussain, Mahrukh Mirza, Rebecca Baines, Lorna Burns, Sebastian Stevens, Sheena Asthana, and Arunangsu Chatterjee

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Longitudinal realist evaluation of the dementia PersonAlised care team (D-PACT) intervention: protocol, Hannah Wheat, Lauren Weston, Tomasina M. Oh, Sarah Morgan-Trimmer, Wendy Ingram, Sarah Griffiths, Rod Sheaff, Paul Clarkson, Antonieta Medina-Lara, Crispin Musicha, Stuart Spicer, Obioha Ukoumunne, Victoria Allgar, Siobhan Creanor, Michael Clark, Cath Quinn, Alex Gude, Rose McCabe, Saqba Batool, Lorna Smith, Debra Richards, Hannah Shafi, Bethany Warwick, Reena Lasrado, Basharat Hussain, Hannah Jones, Sonia Dalkin, Angela Bate, Ian Sherriff, Louise Robinson, and Richard Byng

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UK speech and language therapists’ assessment of children's expressive language, and functional impairment and impact, following the CATALISE publications, Hannah Waine, Sally Bates, Pauline Frizelle, and Tomasina M. Oh

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Improving nocturnal event monitoring in people with intellectual disability in community using an artificial intelligence camera, Sarah Lennard, Rachel Newman, Brendan McLean, Caryn Jory, David Cox, Charlotte Young, Eve Corson, and Rohit Shankar

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The effectiveness of a primary care-based collaborative care model to improve quality of life in people with severe mental illness: PARTNERS2 cluster randomised controlled trial, Richard Byng, Siobhan Creanor, Benjamin Jones, Joanne Hosking, Humera Plappert, Sheriden Bevan, Nicky Britten, Michael Clark, Linda Davies, Julia Frost, Linda Gask, Bliss Gibbons, John Gibson, Pollyanna Hardy, Charley Hobson-Merrett, Peter Huxley, Alison Jeffery, Steven Marwaha, Tim Rawcliffe, Siobhan Reilly, Debra Richards, Ruth Sayers, Lynsey Williams, Vanessa Pinfold, and Maximillian Birchwood