Browse research from the School of Biomedical Sciences.
Submissions from 2024
Comparative evaluation of swabbing sites for Omicron variant detection in PCR testing, Tom Fowler, Edward Blandford, David Chapman, Matthias E Futschik, Raghavendran Kulasegaran-Shylini, Sarah Tunkel, Carolyn Lewis, Alasdair Fellows, Ellie Sheppard, Leanne McCabe, Peter Marks, Paul E Klapper, Andrew Dodgson, Malur Sudhanva, Mike Kidd, Andy Vail, Susan Hopkins, and Tim Peto
Combined effect of sprint interval training and post-exercise blood flow restriction on muscle deoxygenation responses during ramp incremental cycling, Brynmor C. Breese, Stephen J. Bailey, and Richard A. Ferguson
Air quality and mental illness: Role of bioaerosols, causal mechanisms and research priorities, Kamaldeep Bhui, Marcella Ucci, Prashant Kumar, Simon K. Jackson, Corinne Whitby, Ian Colbeck, Christian Pfrang, Zaheer A. Nasir, and Frederic Coulon
Runx2 regulates peripheral nerve regeneration to promote Schwann cell migration and re-myelination, Rong Hu, Xinpeng Dun, Lolita Singh, and Matthew C. Banton
Self-swabbing versus assisted swabbing for viral detection by qRT-PCR: the experience from SARS-CoV-2 based on a meta-analysis of six prospectively designed evaluations conducted in a UK setting, Tom Fowler, David Chapman, Matthias E Futschik, Sarah A Tunkel, Edward Blandford, Elena Turek, Olumide Kolade, Sergio Souza da Cunha, Andrew Dodgson, Paul Klapper, Malur Sudhanva, Lindsey Davies, Sue Hill, Susan Hopkins, and Tim Peto
Endotoxin, a novel biomarker for the rapid risk assessment of faecal contamination of coastal and transitional waters, Simon Jackson, Christian R. Good, Alistair White, and Joao Brandao
Immunogenicity and Protective Capacity of Sugar ABC Transporter Substrate-Binding Protein against Streptococcus suis Serotype 2, 7 and 9 Infection in Mice, Juxiang Liu, Beibei Li, Zujie Yan, Ruyi Pan, Junjie Zhang, Jianhe Sun, Xiaochun Ma, Nihua Dong, Xiaohui Yao, Jianchao Wei, Ke Liu, Yafeng Qiu, Katie Sealey, Hester Nichols, Michael A. Jarvis, Mathew Upton, Xiangdong Li, and Zhiyong Ma
Lysophosphatidylcholine Acetyltransferase 2 (LPCAT2) Influences the Gene Expression of the Lipopolysaccharide Receptor Complex in Infected RAW264.7 Macrophages, Depending on the E. coli Lipopolysaccharide Serotype, Victory Ibigo Poloamina, Hanaa Alrammah, Wondwossen Abate, Neil D. Avent, Gyorgy Fejer, and Simon K. Jackson
Faster detection of asymptomatic COVID-19 cases among care home staff in England through the combination of SARS-CoV-2 testing technologies, Finola Ryan, Joanna Cole-Hamilton, Niharika Dandamudi, Matthias E Futschik, Alexander Needham, Rida Saquib, Raghavendran Kulasegaran-Shylini, Edward Blandford, Michael Kidd, Éamonn O'Moore, Ian Hall, Malur Sudhanva, Paul Klapper, Andrew Dodgson, Adam Moore, Madeleine Duke, Sarah Tunkel, Chris Kenny, and Tom Fowler
Discovery of SQSTM1/p62-dependent P-bodies that regulate the NLRP3 inflammasome, Boxun Lu, Shouqing Luo, Elizabeth R. Barrow, Evelina Valionyte, Chris R. Baxter, Yi Yang, Sharon Herath, William A. O'Connell, Justyna Lopatecka, Alexander Strachan, Waldemar Woznica, Holly N. Stephenson, Gyorgy Fejer, and Vikram Sharma
A simple method for rapid cloning of complete herpesvirus genomes, Wolfram Brune, Jan Knickmann, Laura Staliunaite, Olha Puhach, Eleonore Ostermann, Thomas Günther, Jenna Nichols, Michael A. Jarvis, Sebastian Voigt, Adam Grundhoff, and Andrew J. Davison
Midterm Clinical Outcomes of Reimplantation Versus Remodeling Valve-Sparing Aortic Root Replacement in Patients With Connective Tissue Disorders: A Meta-Analysis, Samuel Burton, Alexander C. Reynolds, Nicola King, Amit Modi, and Sanjay Asopa
Mitochondrial involvement in sarcopenia, Charles Affourtit and Jane E. Carré
Comparison of biomedical science students’ perceptions of online versus paper-based examinations, MMF Subhan, Elizabeth Winters, Kris Jeremy, and William G. Mitchell
Double testing with lateral flow antigen test devices for COVID-19: does a second test in quick succession add value?, Matthias E Futschik, Sarah A Tunkel, Elena Turek, David Chapman, Zareen Thorlu-Bangura, Raghavendran Kulasegaran-Shylini, Edward Blandford, Andrew Dodgson, Paul E Klapper, Malur Sudhanva, Derrick Crook, John Bell, Susan Hopkins, Tim Peto, and Tom Fowler
Editorial: Bacteriocins and other ribosomally synthesised and post-translationally modified peptides (RiPPs) as modulators of the microbiome, Harsh Mathur, Paul D. Cotter, Des Field, Caitriona Guinane, Maire Begley, Mathew Upton, and Hilario C. Mantovani
Rapid antigen testing for SARS-CoV-2 by lateral flow assay: A field evaluation of self- and professional testing at UK community testing sites, Matthias E Futschik, Samuel Johnson, Elena Turek, David Chapman, Simon Carr, Zareen Thorlu-Bangura, Paul E Klapper, Malur Sudhanva, Andrew Dodgson, Joanna R Cole-Hamilton, Nick Germanacos, Raghavendran Kulasegaran-Shylini, Edward Blandford, Sarah Tunkel, Timothy Peto, Susan Hopkins, and Tom Fowler
Short- and Midterm Outcomes of Off- and On-Pump Coronary Artery Bypass in Patients with a Mean Age of 65 or More: Systematic Review and Meta-Analysis, Jake Trotman, Toluwalase Eboka, Neil Smart, and Nicola King
The effect of breathing hypoxic gas (15% FIO2) on physiological and behavioral outcomes during simulated driving in healthy subjects, Mirza M.F. Subhan, Jaspreet Kaur, Lebbathana Manokaran, and Michael Thynne
Submissions from 2023
Urinary tract infections: a review of the current diagnostics landscape, Braith Grey, Mathew Upton, and Lovleen Tina Joshi
Hypoxia-Induced FNDC3B Promotes EGR1/FSTL1 Mediated Angiogenesis in Glioma, de Weijer L van, E Ercolano, T Zhang, M Shah, M Banton, J Na, C Adams, D Hilton, K Kurian, and C Hanemann
An organotypic oral mucosal infection model to study host-pathogen interactions, Samantha J. Gould, Andrew D. Foey, and Vehid M. Salih
Isolation and genome sequencing of cytomegaloviruses from Natal multimammate mice (Mastomys natalensis), Frederick Hansen, Matej Vučak, Jenna Nichols, Joseph Hughes, Sidy Bane, Salvatore Camiolo, Silva Filipe A da, Eleonore Ostermann, Laura Staliunaite, Baca Chan, Thekla Mauch, Nafomon Sogoba, Daniel N. Streblow, Sebastian Voigt, Lisa Oestereich, Bernhard Ehlers, Alec J. Redwood, Heinz Feldmann, Wolfram Brune, Kyle Rosenke, Michael A. Jarvis, and Andrew J. Davison
Toll-like receptor 4 and macrophage scavenger receptor 1 crosstalk regulates phagocytosis of a fungal pathogen, Chinaemerem U. Onyishi, Guillaume E. Desanti, Alex L. Wilkinson, Samuel Lara-Reyna, Eva Maria Frickel, Gyorgy Fejer, Olivier D. Christophe, Clare E. Bryant, Subhankar Mukhopadhyay, Siamon Gordon, and Robin C. May
Calculation of ATP production rates using the Seahorse XF Analyzer, Brandon R. Desousa, Kristen K.O. Kim, Anthony E. Jones, Andréa B. Ball, Wei Y. Hsieh, Pamela Swain, Danielle H. Morrow, Alexandra J. Brownstein, David A. Ferrick, Orian S. Shirihai, Andrew Neilson, David A. Nathanson, George W. Rogers, Brian P. Dranka, Anne N. Murphy, Charles Affourtit, Steven J. Bensinger, Linsey Stiles, Natalia Romero, and Ajit S. Divakaruni
An attenuated herpesvirus vectored vaccine candidate induces T-cell responses against highly conserved porcine reproductive and respiratory syndrome virus M and NSP5 proteins that are unable to control infection, Brito RCF de, Kerry Holtham, Jessica Roser, Jack E. Saunders, Yvonne Wezel, Summer Henderson, Thekla Mauch, Beatriz Sanz-Bernardo, Jean Pierre Frossard, Matthieu Bernard, Fabian Z.X. Lean, Alejandro Nunez, Simon Gubbins, Nicolás M. Suárez, Andrew J. Davison, Michael J. Francis, Michael Huether, Hafid Benchaoui, Jeremy Salt, Veronica L. Fowler, Michael A. Jarvis, and Simon P. Graham
What’s really down the hospital plughole?, J. Butler and M. Upton
RHD molecular analysis—from discovery to next generation sequencing, Tracey E. Madgett, Wajnat A. Tounsi, Amr J. Halawani, and Neil D. Avent
A Comparative Meta-Analysis Identifying Salivary Cytokines, IL-6, IL-8 and TNF-a, and Lactate Dehydrogenase as Potential Non-Invasive Diagnostic Biomarkers of Oral Squamous Cell Carcinoma, Vehid Salih, Matthew Perry, Mohammed Haseeb Chohan, Paul Laurance-Young, and Andrew Foey
The Potential of Probiotics as Ingestible Adjuvants and Immune Modulators for Antiviral Immunity and Management of SARS-CoV-2 Infection and COVID-19, Sophie Tomkinson, Cloe Triscott, Emily Schenk, and Andrew Foey
A metabologenomics approach to unlock the metabolome of the novel Antarctic deep-sea isolate Lacinutrix shetlandiensis sp. nov. WUR7, Giovanni A. Vitale, Grant G. January, Ernest Oppong-Danquah, Sala G Della, Esposito F Palma, Deniz Tasdemir, and Pascale D de
Air quality and mental health: evidence, challenges and future directions, Kamaldeep Bhui, Joanne B. Newbury, Rachel M. Latham, Marcella Ucci, Zaheer A. Nasir, Briony Turner, Catherine O'Leary, Helen L. Fisher, Emma Marczylo, Philippa Douglas, Stephen Stansfeld, Simon K. Jackson, Sean Tyrrel, Andrey Rzhetsky, Rob Kinnersley, Prashant Kumar, Caroline Duchaine, and Frederic Coulon
Bovine Herpesvirus-4 Based Vaccine Provides Protective Immunity against Streptococcus suis Disease in a Rabbit Model, Nihua Dong, Hester Nichols, Q Sun, Xiaojun Chen, Jiayang Zheng, Zhixin Guan, Hailong Zhang, Andrew Davison, Yvonne Wezel, Z Li, B Li, Ke Liu, Donghua Shao, Yafeng Qiu, J Sun, X Li, Mathew Upton, Zhiyong Ma, Michael A. Jarvis, and Jianchao Wei
Genistein and coumestrol reduce MCF-7 breast cancer cell viability and inhibit markers of preferential metastasis, bone matrix attachment and tumor-induced osteoclastogenesis, Mezban S. Al-Thamiree and SW Fox
The effects of acute hypoxia on cognitive and cardiovascular parameters in healthy subjects, R Ravi and MMF Subhan
Combined molnupiravir-nirmatrelvir treatment improves the inhibitory effect on SARS-CoV-2 in macaques, Kyle Rosenke, Matt C. Lewis, F Feldmann, Eric Bohrnsen, Benjamin Schwarz, Atsushi Okumura, W. Forrest Bohler, Julie Callison, Carl Shaia, Catharine M. Bosio, Jamie Lovaglio, Greg Saturday, Michael A. Jarvis, and H Feldmann
Whole genomes of deep-sea sponge-associated bacteria exhibit high novel natural product potential, Poppy J. Hesketh-Best, Grant G. January, Matthew J. Koch, Philip J. Warburton, Kerry L. Howell, and Mathew Upton
Optimization of sniff nasal inspiratory pressure (SNIP) measurement methodology in healthy subjects., M Subhan
Is penicillin allergy de-labelling about to find its place in UK antimicrobial stewardship strategy?, Neil Powell, Mathew Upton, Bridie Kent, Sarah Tonkin-Crine, and Jonathan Sandoe
Subunit Vaccine Targeting Phosphate ABC Transporter ATP-Binding Protein, PstB, Provides Cross-Protection against Streptococcus suis Serotype 2, 7, and 9 in Mice, Zujie Yan, Xiaohui Yao, Ruyi Pan, Junjie Zhang, X Ma, Nihua Dong, Jianchao Wei, K Liu, Yafeng Qiu, Katie Sealey, Hester Nichols, Michael A. Jarvis, Mathew Upton, X Li, Z Ma, J Liu, and B Li
Subunit Vaccine Targeting Phosphate ABC Transporter ATP-Binding Protein, PstB, Provides Cross-Protection against Streptococcus suis Serotype 2, 7, and 9 in Mice, Zujie Yan, Xiaohui Yao, Ruyi Pan, Junjie Zhang, X Ma, Nihua Dong, Jianchao Wei, K Liu, Yafeng Qiu, Katie Sealey, Hester Nichols, Michael A. Jarvis, Mathew Upton, X Li, Z Ma, J Liu, and B Li
Supervised physical activity and the incidence of gestational diabetes mellitus: a systematic review and meta-analysis, G. Bennett, N. King, K. Redfern, and B. C. Breese
Transcatheter aortic valve implantation versus surgical aortic valve replacement in dialysis-dependent patients: a meta-analysis, Samuel Burton, Alexander Reynolds, Nicola King, Amit Modi, and Sanjay Asopa
Submissions from 2022
Endotoxin as a Marker for Water Quality, Anas A. Sattar, Christian R. Good, Margaux Saletes, João Brandão, and Simon K. Jackson
Dietary Intakes of Folate, Vitamin D and Iodine during the First Trimester of Pregnancy and the Association between Supplement Use and Demographic Characteristics amongst White Caucasian Women Living with Obesity in the UK, Kathy M. Redfern, Heidi J. Hollands, C. Ross Welch, Jonathan H. Pinkney, and Gail A. Rees
OXA-66 structure and oligomerisation of OXAAb enzymes, Y Takebayashi, SR Henderson, DY Chirgadze, PJ Warburton, and BA Evans
Metabolomics Profiling of Vitamin D Status in Relation to Dyslipidemia, Hanaa Mousa, Mohamed A. Elrayess, Ilhame Diboun, Simon K. Jackson, and Susu M. Zughaier
Nitrite lowers the oxygen cost of ATP supply in cultured skeletal muscle cells by stimulating the rate of glycolytic ATP synthesis, Anthony G. Wynne and Charles Affourtit
Possible Regulation of Toll-Like Receptor 4 By Lysine Acetylation Through LPCAT2 Activity in RAW264.7 Cells., Victory Ibigo Poloamina, Wondwossen Abate, Gyorgy Fejer, and Simon K. Jackson
Molnupiravir inhibits SARS-CoV-2 variants including Omicron in the hamster model, K Rosenke, Atsushi Okumura, Matthew C. Lewis, F Feldmann, Kimberly Meade-White, W. Forrest Bohler, Amanda Griffin, R Rosenke, Carl Shaia, Michael A. Jarvis, and H Feldmann
Acute bioenergetic insulin sensitivity of skeletal muscle cells: ATP-demand-provoked glycolysis contributes to stimulation of ATP supply, Rosie A. Donnell, Jane E. Carré, and Charles Affourtit
Hypertension alters the function and expression profile of the peptide cotransporters PEPT1 and PEPT2 in the rodent renal proximal tubule, Othman A. Alghamdi, Nicola King, Nicholas M. Andronicos, Graham L. Jones, Belal Chami, Paul K. Witting, and Pierre D.J. Moens
First Trimester Noninvasive Prenatal Diagnosis of Maternally Inherited Beta-Thalassemia Mutations, Tracey E. Madgett
Rh Blood Group D Antigen Genotyping Using a Portable Nanopore-based Sequencing Device: Proof of Principle, Tracey E. Madgett, Wajnat A. Tounsi, Vasileios P. Lenis, Silja M. Tammi, Susanna Sainio, Katri Haimila, and Neil D. Avent
Epstein-Barr Virus-Encoded BILF1 Orthologues From Porcine Lymphotropic Herpesviruses Display Common Molecular Functionality, Maša Mavri, Valentina Kubale, Daniel P. Depledge, Jianmin Zuo, Christene A. Huang, Judith Breuer, Milka Vrecl, Michael A. Jarvis, Eva Jarc Jovičić, Toni Petan, Bernhard Ehlers, Mette M. Rosenkilde, and Katja Spiess
The Impact of Waxy Wheat Flour, Inulin and Guar Gum on Post-Prandial Glycaemic and Satiety Indices, Sensory Attributes and Shelf Life of Tandoori and Pita Breads, Yaseen Galali, Gail Rees, and Victor Kuri
SARS-CoV-2 reinfection prevents acute respiratory disease in Syrian hamsters but not replication in the upper respiratory tract, Frederick Hansen, Kimberly Meade-White, Chad Clancy, R Rosenke, Atsushi Okumura, David W. Hawman, F Feldmann, Benjamin Kaza, Michael A. Jarvis, K Rosenke, and H Feldmann
Three-Week Old Pigs Are Not Susceptible to Productive Infection with SARS-COV-2, Elaine Haddock, Julie Callison, Stephanie N. Seifert, Atsushi Okumura, Tsing Lee Tang-Huau, Shanna S. Leventhal, Matthew C. Lewis, Jamie Lovaglio, Patrick W. Hanley, Carl Shaia, David W. Hawman, Vincent J. Munster, Michael A. Jarvis, Juergen A. Richt, and Heinz Feldmann
Hospital sink traps as a potential source of the emerging multidrug-resistant pathogen Cupriavidus pauculus: characterization and draft genome sequence of strain MF1, James Butler, Sean D. Kelly, Katie J. Muddiman, Alexandros Besinis, and Mathew Upton
Do Micronutrient and Omega-3 Fatty Acid Supplements Affect Human Maternal Immunity during Pregnancy? A Scoping Review, G Rees, L Brough, GM Orsatti, A Lodge, and S Walker
Submissions from 2021
Air quality and mental health: evidence, challenges and future directions, K Bhui, J Newbury, R Latham, M Ucci, Z Nasar, B Turner, C O'Leary, HL Fisher, E Marczylo, P Douglas, S Stansfeld, S Jackson, S Tyrrel, A Rzhetsky, R Kinnersley, P Kumar, C Duchaine, and F Coulon
Impact of growth media and pressure on the diversity and antimicrobial activity of isolates from two species of hexactinellid sponge, Matthew J. Koch, Poppy J. Hesketh-Best, Gary Smerdon, Philip J. Warburton, Kerry Howell, and Mathew Upton
Single-Cell Regulatory Network Inference and Clustering Identifies Cell-Type Specific Expression Pattern of Transcription Factors in Mouse Sciatic Nerve, Mingchao Li, Qing Min, Matthew C. Banton, and Xinpeng Dun
UK B.1.1.7 (Alpha) variant exhibits increased respiratory replication and shedding in nonhuman primates, Kyle Rosenke, F Feldmann, Atsushi Okumura, Frederick Hansen, Tsing Lee Tang-Huau, Kimberly Meade-White, Benjamin Kaza, Julie Callison, Matthew C. Lewis, Brian J. Smith, Patrick W. Hanley, Jamie Lovaglio, Michael A. Jarvis, Carl Shaia, and H Feldmann
Meta-Analysis Reveals Transcription Factor Upregulation in Cells of Injured Mouse Sciatic Nerve, Mingchao Li, Matthew C. Banton, Qing Min, David B. Parkinson, and Xinpeng Dun
Plasmid fitness costs are caused by specific genetic conflicts enabling resolution by compensatory mutation, JPJ Hall, RCT Wright, E Harrison, KJ Muddiman, AJ Wood, S Paterson, and MA Brockhurst
Forward and Reverse Genetics of B Cell Malignancies: From Insertional Mutagenesis to CRISPR-Cas, Joanna C. Dawes and Anthony G. Uren
Respiratory Parameters for the Classification of Dysfunctional Insulin Secretion by Pancreatic Islets, Uma D. Kabra, Charles Affourtit, and Martin Jastroch
UK B.1.1.7 variant exhibits increased respiratory replication and shedding in nonhuman primates, K Rosenke, F Feldmann, A Okumura, F Hansen, T Tang-Huau, K Meade-White, B Kaza, BJ Smith, PW Hanley, J Lovaglio, MA Jarvis, C Shaia, and H Feldmann
Editorial: Bacteriocins and Other Ribosomally Synthesised and Post-translationally Modified Peptides (RiPPs) as Alternatives to Antibiotics, Harsh Mathur, Des Field, Mathew Upton, and Paul D. Cotter
Study the influence of waxy wheat flour, inulin and guar gum on quality and microstructure of Pita and Tandoori breads: response surface methodology aids functional food development, Yaseen Galali, Gail Rees, and Victor Kuri
Effect of methionine feeding on oxidative stress, intracellular calcium and contractility in cardiomyocytes isolated from male and female rats, Shatha A. Demerchi, Nicola King, James R. McFarlane, and Pierre D.J. Moens
Mastomys natalensis Has a Cellular Immune Response Profile Distinct from Laboratory Mice, Tsing Lee Tang-Huau, Kyle Rosenke, Kimberly Meade-White, Aaron Carmody, Brian J. Smith, Catharine M. Bosio, Michael A. Jarvis, and Heinz Feldmann
Orally delivered MK-4482 inhibits SARS-CoV-2 replication in the Syrian hamster model, K Rosenke, Frederick Hansen, Benjamin Schwarz, F Feldmann, Elaine Haddock, R Rosenke, Kent Barbian, Kimberly Meade-White, Atsushi Okumura, Shanna Leventhal, David W. Hawman, Emily Ricotta, Catharine M. Bosio, Craig Martens, Greg Saturday, H Feldmann, and Michael A. Jarvis
Lassa Virus Treatment Options, Frederick Hansen, Michael A. Jarvis, Heinz Feldmann, and Kyle Rosenke
HTK versus multidose cardioplegias for myocardial protection in adult cardiac surgery: A meta‐analysis, Alexander C. Reynolds, Sanjay Asopa, Amit Modi, and Nicola King
Single Cell Transcriptome Data Analysis Defines the Heterogeneity of Peripheral Nerve Cells in Homeostasis and Regeneration, Bing Chen, Matthew C. Banton, Lolita Singh, David B. Parkinson, and Xin Peng Dun
Pandemic Struggles of the Mad Professor, Nicola King
Drug repurposing for next-generation combination therapies against multidrug-resistant bacteria, Yuan Liu, Ziwen Tong, Jingru Shi, Ruichao Li, Mathew Upton, and Zhiqiang Wang
Targeting Ebola virus replication through pharmaceutical intervention, Frederick Hansen, Heinz Feldmann, and Michael A. Jarvis
Bridging the gap: Using reservoir ecology and human serosurveys to estimate Lassa virus spillover in West Africa, Andrew J. Basinski, Elisabeth Fichet-Calvet, Anna R. Sjodin, Tanner J. Varrelman, Christopher H. Remien, Nathan C. Layman, Brian H. Bird, David J. Wolking, Corina Monagin, Bruno M. Ghersi, Peter A. Barry, Michael A. Jarvis, Paul E. Gessler, and Scott L. Nuismer
The relationship between gestational weight gain, maternal upper-body subcutaneous fat changes and infant birth size: a pilot observational study amongst women with obesity, Kathy M. Redfern, Heidi J. Hollands, Joanne Hosking, C. Ross Welch, Jonathan H. Pinkney, and Gail A. Rees
Fat mass prediction equations and reference ranges for Saudi Arabian Children aged 8–12 years using machine technique method, RB Alkutbe, A Alruban, H Alturki, A Sattar, H Al-Hazzaa, and G Rees
Variability in carbapenemase activity of intrinsic OxaAb (OXA-51-like) β-lactamase enzymes in Acinetobacter baumannii., Yuiko Takebayashi, Jacqueline Findlay, Kate J. Heesom, Philip J. Warburton, Matthew B. Avison, and Benjamin A. Evans
The Phylogenetic Structure of Reptile, Avian and Uropathogenic Escherichia coli with Particular Reference to Extraintestinal Pathotypes, Marta Książczyk, Bartłomiej Dudek, Maciej Kuczkowski, Robert O’Hara, Kamila Korzekwa, Anna Wzorek, Agnieszka Korzeniowska-Kowal, Mathew Upton, Adam Junka, Alina Wieliczko, Radosław Ratajszczak, and Gabriela Bugla-Płoskońska
Effect of ageing and hypertension on the expression and activity of PEPT2 in normal and hypertrophic hearts, Othman Alghamdi, Nicola King, Graham L. Jones, and Pierre D.J. Moens
Submissions from 2020
Defining the Syrian hamster as a highly susceptible preclinical model for SARS-CoV-2 infection, Kyle Rosenke, Kimberly Meade-White, Michael Letko, Chad Clancy, Frederick Hansen, Yanan Liu, Atsushi Okumura, Tsing Lee Tang-Huau, Rong Li, Greg Saturday, F Feldmann, Dana Scott, Zhongde Wang, Vincent Munster, Michael A. Jarvis, and H Feldmann
A rapid response vaccine development strategy for newcastle disease in poultry, SR R. Maremagae, CC C. Bezuidenhout, AM M. Murphy, MA A. Jarvis, P Naicker, and P. J. Lebea
Hydroxychloroquine prophylaxis and treatment is ineffective in macaque and hamster SARS-CoV-2 disease models, Kyle Rosenke, Michael A. Jarvis, F Feldmann, Benjamin Schwarz, Atsushi Okumura, Jamie Lovaglio, Greg Saturday, Patrick W. Hanley, Kimberly Meade-White, Brandi N. Williamson, Frederick Hansen, L Pérez-Pérez, Shanna Leventhal, Tsing Lee Tang-Huau, Julie Callison, Elaine Haddock, Kaitlin A. Stromberg, Graham Sewell, Dana Scott, Catharine M. Bosio, David Hawman, Wit E de, and H Feldmann
Characterising a human endogenous retrovirus(HERV)-derived tumour-associated antigen: enriched RNA-Seq analysis of HERV-K(HML-2) in mantle cell lymphoma cell lines, Witold Tatkiewicz, James Dickie, Franchesca Bedford, Alexander Jones, Mark Atkin, Michele Kiernan, Emmanuel Atangana Maze, Bora Agit, Garry Farnham, Alexander Kanapin, and Robert Belshaw
Next-generation sequencing of 35 RHD variants in 16 253 serologically D− pregnant women in the Finnish population, Silja M. Tammi, Wajnat A. Tounsi, Susanna Sainio, Michele Kiernan, Neil D. Avent, Tracey E. Madgett, and Katri Haimila
Microplegia in cardiac surgery: Systematic review and meta‐analysis, Claire M. Owen, Sanjay Asopa, Neil A. Smart, and Nicola King
Multiple DNA viruses identified in multimammate mouse (Mastomys natalensis) populations from across regions of sub-Saharan Africa, Sébastien Calvignac-Spencer, Léonce Kouadio, Emmanuel Couacy-Hymann, Nafomon Sogoba, Kyle Rosenke, Andrew J. Davison, Fabian Leendertz, Michael A. Jarvis, Heinz Feldmann, and Bernhard Ehlers
Modulation of Rab7a-mediated growth factor receptor trafficking inhibits islet beta cell apoptosis and autophagy under conditions of metabolic stress, Nirun V. Hewawasam, Fadel Lhaf, Henry A. Taylor, Katrina Viloria, Amazon Austin, Aileen King, P Jones, L Jones, Mark D. Turner, and Natasha J. Hill
Bayesian estimation of Lassa virus epidemiological parameters: Implications for spillover prevention using wildlife vaccination, Scott L. Nuismer, Christopher H. Remien, Andrew J. Basinski, Tanner Varrelman, Nathan Layman, Kyle Rosenke, Brian Bird, Michael Jarvis, Peter Barry, Patrick W. Hanley, and Elisabeth Fichet-Calvet
Plasmodium berghei LAPs form an extended protein complex that facilitates crystalloid targeting and biogenesis, Annie Z. Tremp, Sadia Saeed, Vikram Sharma, Edwin Lasonder, and Johannes T. Dessens
The High Osmolarity Glycerol Mitogen-Activated Protein Kinase regulates glucose catabolite repression in filamentous fungi, Gerhard H. Braus, Assis LJ de, LP Silva, Li Liu, Kerstin Schmitt, Oliver Valerius, LNA Ries, and GH Goldman
Evaluation of drugs for potential repurposing against COVID-19 using a tier-based scoring system, Michael A. Jarvis, Frederick A. Hansen, Kyle Rosenke, Elaine Haddock, Christopher Rollinson, Simon Rule, Graham Sewell, Andrew Hughes, and Heinz Feldmann
Flowering poration – a synergistic multi-mode antibacterial mechanism by a bacteriocin fold, Katharine Hammond, Helen Lewis, Samantha Halliwell, Florie Desriac, Brunello Nardone, Jascindra Ravi, Bart W. Hoogenboom, Mathew Upton, Jeremy P. Derrick, and Maxim G. Ryadnov
The Aspergillus fumigatus transcription factor RglT is important for gliotoxin biosynthesis and self-protection, and virulence, Laure N.A. Ries, Lakhansing Pardeshi, Zhiqiang Dong, Kaeling Tan, Jacob L. Steenwyk, Ana Cristina Colabardini, Filho JA Ferreira, Castro PA de, Lilian P. Silva, Nycolas W. Preite, Fausto Almeida, Assis LJ de, Santos RAC dos, Paul Bowyer, Michael Bromley, Rebecca A. Owens, Sean Doyle, Marilene Demasi, Diego C.R. Hernández, Luís Eduardo S. Netto, Monica T. Pupo, Antonis Rokas, Flavio V. Loures, Koon H. Wong, and Gustavo H. Goldman
