Browse research from the School of Biomedical Sciences.

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Submissions from 2024

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Air quality and mental illness: Role of bioaerosols, causal mechanisms and research priorities, Kamaldeep Bhui, Marcella Ucci, Prashant Kumar, Simon K. Jackson, Corinne Whitby, Ian Colbeck, Christian Pfrang, Zaheer A. Nasir, and Frederic Coulon

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Runx2 regulates peripheral nerve regeneration to promote Schwann cell migration and re-myelination, Rong Hu, Xinpeng Dun, Lolita Singh, and Matthew C. Banton

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Endotoxin, a novel biomarker for the rapid risk assessment of faecal contamination of coastal and transitional waters, Simon Jackson, Christian R. Good, Alistair White, and Joao Brandao

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Immunogenicity and Protective Capacity of Sugar ABC Transporter Substrate-Binding Protein against Streptococcus suis Serotype 2, 7 and 9 Infection in Mice, Juxiang Liu, Beibei Li, Zujie Yan, Ruyi Pan, Junjie Zhang, Jianhe Sun, Xiaochun Ma, Nihua Dong, Xiaohui Yao, Jianchao Wei, Ke Liu, Yafeng Qiu, Katie Sealey, Hester Nichols, Michael A. Jarvis, Mathew Upton, Xiangdong Li, and Zhiyong Ma

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Lysophosphatidylcholine Acetyltransferase 2 (LPCAT2) Influences the Gene Expression of the Lipopolysaccharide Receptor Complex in Infected RAW264.7 Macrophages, Depending on the E. coli Lipopolysaccharide Serotype, Victory Ibigo Poloamina, Hanaa Alrammah, Wondwossen Abate, Neil D. Avent, Gyorgy Fejer, and Simon K. Jackson

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Discovery of SQSTM1/p62-dependent P-bodies that regulate the NLRP3 inflammasome, Boxun Lu, Shouqing Luo, Elizabeth R. Barrow, Evelina Valionyte, Chris R. Baxter, Yi Yang, Sharon Herath, William A. O'Connell, Justyna Lopatecka, Alexander Strachan, Waldemar Woznica, Holly N. Stephenson, Gyorgy Fejer, and Vikram Sharma

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A simple method for rapid cloning of complete herpesvirus genomes, Wolfram Brune, Jan Knickmann, Laura Staliunaite, Olha Puhach, Eleonore Ostermann, Thomas Günther, Jenna Nichols, Michael A. Jarvis, Sebastian Voigt, Adam Grundhoff, and Andrew J. Davison

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Midterm Clinical Outcomes of Reimplantation Versus Remodeling Valve-Sparing Aortic Root Replacement in Patients With Connective Tissue Disorders: A Meta-Analysis, Samuel Burton, Alexander C. Reynolds, Nicola King, Amit Modi, and Sanjay Asopa

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Mitochondrial involvement in sarcopenia, Charles Affourtit and Jane E. Carré

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Editorial: Bacteriocins and other ribosomally synthesised and post-translationally modified peptides (RiPPs) as modulators of the microbiome, Harsh Mathur, Paul D. Cotter, Des Field, Caitriona Guinane, Maire Begley, Mathew Upton, and Hilario C. Mantovani

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Short- and Midterm Outcomes of Off- and On-Pump Coronary Artery Bypass in Patients with a Mean Age of 65 or More: Systematic Review and Meta-Analysis, Jake Trotman, Toluwalase Eboka, Neil Smart, and Nicola King

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The effect of breathing hypoxic gas (15% FIO2) on physiological and behavioral outcomes during simulated driving in healthy subjects, Mirza M.F. Subhan, Jaspreet Kaur, Lebbathana Manokaran, and Michael Thynne

Submissions from 2023

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Urinary tract infections: a review of the current diagnostics landscape, Braith Grey, Mathew Upton, and Lovleen Tina Joshi

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An organotypic oral mucosal infection model to study host-pathogen interactions, Samantha J. Gould, Andrew D. Foey, and Vehid M. Salih

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Isolation and genome sequencing of cytomegaloviruses from Natal multimammate mice (Mastomys natalensis), Frederick Hansen, Matej Vučak, Jenna Nichols, Joseph Hughes, Sidy Bane, Salvatore Camiolo, Silva Filipe A da, Eleonore Ostermann, Laura Staliunaite, Baca Chan, Thekla Mauch, Nafomon Sogoba, Daniel N. Streblow, Sebastian Voigt, Lisa Oestereich, Bernhard Ehlers, Alec J. Redwood, Heinz Feldmann, Wolfram Brune, Kyle Rosenke, Michael A. Jarvis, and Andrew J. Davison

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Toll-like receptor 4 and macrophage scavenger receptor 1 crosstalk regulates phagocytosis of a fungal pathogen, Chinaemerem U. Onyishi, Guillaume E. Desanti, Alex L. Wilkinson, Samuel Lara-Reyna, Eva Maria Frickel, Gyorgy Fejer, Olivier D. Christophe, Clare E. Bryant, Subhankar Mukhopadhyay, Siamon Gordon, and Robin C. May

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Calculation of ATP production rates using the Seahorse XF Analyzer, Brandon R. Desousa, Kristen K.O. Kim, Anthony E. Jones, Andréa B. Ball, Wei Y. Hsieh, Pamela Swain, Danielle H. Morrow, Alexandra J. Brownstein, David A. Ferrick, Orian S. Shirihai, Andrew Neilson, David A. Nathanson, George W. Rogers, Brian P. Dranka, Anne N. Murphy, Charles Affourtit, Steven J. Bensinger, Linsey Stiles, Natalia Romero, and Ajit S. Divakaruni

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An attenuated herpesvirus vectored vaccine candidate induces T-cell responses against highly conserved porcine reproductive and respiratory syndrome virus M and NSP5 proteins that are unable to control infection, Brito RCF de, Kerry Holtham, Jessica Roser, Jack E. Saunders, Yvonne Wezel, Summer Henderson, Thekla Mauch, Beatriz Sanz-Bernardo, Jean Pierre Frossard, Matthieu Bernard, Fabian Z.X. Lean, Alejandro Nunez, Simon Gubbins, Nicolás M. Suárez, Andrew J. Davison, Michael J. Francis, Michael Huether, Hafid Benchaoui, Jeremy Salt, Veronica L. Fowler, Michael A. Jarvis, and Simon P. Graham

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What’s really down the hospital plughole?, J. Butler and M. Upton

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RHD molecular analysis—from discovery to next generation sequencing, Tracey E. Madgett, Wajnat A. Tounsi, Amr J. Halawani, and Neil D. Avent

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A Comparative Meta-Analysis Identifying Salivary Cytokines, IL-6, IL-8 and TNF-a, and Lactate Dehydrogenase as Potential Non-Invasive Diagnostic Biomarkers of Oral Squamous Cell Carcinoma, Vehid Salih, Matthew Perry, Mohammed Haseeb Chohan, Paul Laurance-Young, and Andrew Foey

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The Potential of Probiotics as Ingestible Adjuvants and Immune Modulators for Antiviral Immunity and Management of SARS-CoV-2 Infection and COVID-19, Sophie Tomkinson, Cloe Triscott, Emily Schenk, and Andrew Foey

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A metabologenomics approach to unlock the metabolome of the novel Antarctic deep-sea isolate Lacinutrix shetlandiensis sp. nov. WUR7, Giovanni A. Vitale, Grant G. January, Ernest Oppong-Danquah, Sala G Della, Esposito F Palma, Deniz Tasdemir, and Pascale D de

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Air quality and mental health: evidence, challenges and future directions, Kamaldeep Bhui, Joanne B. Newbury, Rachel M. Latham, Marcella Ucci, Zaheer A. Nasir, Briony Turner, Catherine O'Leary, Helen L. Fisher, Emma Marczylo, Philippa Douglas, Stephen Stansfeld, Simon K. Jackson, Sean Tyrrel, Andrey Rzhetsky, Rob Kinnersley, Prashant Kumar, Caroline Duchaine, and Frederic Coulon

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Bovine Herpesvirus-4 Based Vaccine Provides Protective Immunity against Streptococcus suis Disease in a Rabbit Model, Nihua Dong, Hester Nichols, Q Sun, Xiaojun Chen, Jiayang Zheng, Zhixin Guan, Hailong Zhang, Andrew Davison, Yvonne Wezel, Z Li, B Li, Ke Liu, Donghua Shao, Yafeng Qiu, J Sun, X Li, Mathew Upton, Zhiyong Ma, Michael A. Jarvis, and Jianchao Wei

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Genistein and coumestrol reduce MCF-7 breast cancer cell viability and inhibit markers of preferential metastasis, bone matrix attachment and tumor-induced osteoclastogenesis, Mezban S. Al-Thamiree and SW Fox

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The effects of acute hypoxia on cognitive and cardiovascular parameters in healthy subjects, R Ravi and MMF Subhan

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Combined molnupiravir-nirmatrelvir treatment improves the inhibitory effect on SARS-CoV-2 in macaques, Kyle Rosenke, Matt C. Lewis, F Feldmann, Eric Bohrnsen, Benjamin Schwarz, Atsushi Okumura, W. Forrest Bohler, Julie Callison, Carl Shaia, Catharine M. Bosio, Jamie Lovaglio, Greg Saturday, Michael A. Jarvis, and H Feldmann

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Whole genomes of deep-sea sponge-associated bacteria exhibit high novel natural product potential, Poppy J. Hesketh-Best, Grant G. January, Matthew J. Koch, Philip J. Warburton, Kerry L. Howell, and Mathew Upton

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Optimization of sniff nasal inspiratory pressure (SNIP) measurement methodology in healthy subjects., M Subhan

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Is penicillin allergy de-labelling about to find its place in UK antimicrobial stewardship strategy?, Neil Powell, Mathew Upton, Bridie Kent, Sarah Tonkin-Crine, and Jonathan Sandoe

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Subunit Vaccine Targeting Phosphate ABC Transporter ATP-Binding Protein, PstB, Provides Cross-Protection against Streptococcus suis Serotype 2, 7, and 9 in Mice, Zujie Yan, Xiaohui Yao, Ruyi Pan, Junjie Zhang, X Ma, Nihua Dong, Jianchao Wei, K Liu, Yafeng Qiu, Katie Sealey, Hester Nichols, Michael A. Jarvis, Mathew Upton, X Li, Z Ma, J Liu, and B Li

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Subunit Vaccine Targeting Phosphate ABC Transporter ATP-Binding Protein, PstB, Provides Cross-Protection against Streptococcus suis Serotype 2, 7, and 9 in Mice, Zujie Yan, Xiaohui Yao, Ruyi Pan, Junjie Zhang, X Ma, Nihua Dong, Jianchao Wei, K Liu, Yafeng Qiu, Katie Sealey, Hester Nichols, Michael A. Jarvis, Mathew Upton, X Li, Z Ma, J Liu, and B Li

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Supervised physical activity and the incidence of gestational diabetes mellitus: a systematic review and meta-analysis, G. Bennett, N. King, K. Redfern, and B. C. Breese

Submissions from 2022

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Endotoxin as a Marker for Water Quality, Anas A. Sattar, Christian R. Good, Margaux Saletes, João Brandão, and Simon K. Jackson

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Dietary Intakes of Folate, Vitamin D and Iodine during the First Trimester of Pregnancy and the Association between Supplement Use and Demographic Characteristics amongst White Caucasian Women Living with Obesity in the UK, Kathy M. Redfern, Heidi J. Hollands, C. Ross Welch, Jonathan H. Pinkney, and Gail A. Rees

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OXA-66 structure and oligomerisation of OXAAb enzymes, Y Takebayashi, SR Henderson, DY Chirgadze, PJ Warburton, and BA Evans

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Metabolomics Profiling of Vitamin D Status in Relation to Dyslipidemia, Hanaa Mousa, Mohamed A. Elrayess, Ilhame Diboun, Simon K. Jackson, and Susu M. Zughaier

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Nitrite lowers the oxygen cost of ATP supply in cultured skeletal muscle cells by stimulating the rate of glycolytic ATP synthesis, Anthony G. Wynne and Charles Affourtit

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Possible Regulation of Toll-Like Receptor 4 By Lysine Acetylation Through LPCAT2 Activity in RAW264.7 Cells., Victory Ibigo Poloamina, Wondwossen Abate, Gyorgy Fejer, and Simon K. Jackson

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Molnupiravir inhibits SARS-CoV-2 variants including Omicron in the hamster model, K Rosenke, Atsushi Okumura, Matthew C. Lewis, F Feldmann, Kimberly Meade-White, W. Forrest Bohler, Amanda Griffin, R Rosenke, Carl Shaia, Michael A. Jarvis, and H Feldmann

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Acute bioenergetic insulin sensitivity of skeletal muscle cells: ATP-demand-provoked glycolysis contributes to stimulation of ATP supply, Rosie A. Donnell, Jane E. Carré, and Charles Affourtit

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Hypertension alters the function and expression profile of the peptide cotransporters PEPT1 and PEPT2 in the rodent renal proximal tubule, Othman A. Alghamdi, Nicola King, Nicholas M. Andronicos, Graham L. Jones, Belal Chami, Paul K. Witting, and Pierre D.J. Moens

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First Trimester Noninvasive Prenatal Diagnosis of Maternally Inherited Beta-Thalassemia Mutations, Tracey E. Madgett

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Rh Blood Group D Antigen Genotyping Using a Portable Nanopore-based Sequencing Device: Proof of Principle, Tracey E. Madgett, Wajnat A. Tounsi, Vasileios P. Lenis, Silja M. Tammi, Susanna Sainio, Katri Haimila, and Neil D. Avent

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Epstein-Barr Virus-Encoded BILF1 Orthologues From Porcine Lymphotropic Herpesviruses Display Common Molecular Functionality, Maša Mavri, Valentina Kubale, Daniel P. Depledge, Jianmin Zuo, Christene A. Huang, Judith Breuer, Milka Vrecl, Michael A. Jarvis, Eva Jarc Jovičić, Toni Petan, Bernhard Ehlers, Mette M. Rosenkilde, and Katja Spiess

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The Impact of Waxy Wheat Flour, Inulin and Guar Gum on Post-Prandial Glycaemic and Satiety Indices, Sensory Attributes and Shelf Life of Tandoori and Pita Breads, Yaseen Galali, Gail Rees, and Victor Kuri

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SARS-CoV-2 reinfection prevents acute respiratory disease in Syrian hamsters but not replication in the upper respiratory tract, Frederick Hansen, Kimberly Meade-White, Chad Clancy, R Rosenke, Atsushi Okumura, David W. Hawman, F Feldmann, Benjamin Kaza, Michael A. Jarvis, K Rosenke, and H Feldmann

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Three-Week Old Pigs Are Not Susceptible to Productive Infection with SARS-COV-2, Elaine Haddock, Julie Callison, Stephanie N. Seifert, Atsushi Okumura, Tsing Lee Tang-Huau, Shanna S. Leventhal, Matthew C. Lewis, Jamie Lovaglio, Patrick W. Hanley, Carl Shaia, David W. Hawman, Vincent J. Munster, Michael A. Jarvis, Juergen A. Richt, and Heinz Feldmann

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Hospital sink traps as a potential source of the emerging multidrug-resistant pathogen Cupriavidus pauculus: characterization and draft genome sequence of strain MF1, James Butler, Sean D. Kelly, Katie J. Muddiman, Alexandros Besinis, and Mathew Upton

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Do Micronutrient and Omega-3 Fatty Acid Supplements Affect Human Maternal Immunity during Pregnancy? A Scoping Review, G Rees, L Brough, GM Orsatti, A Lodge, and S Walker

Submissions from 2021

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Air quality and mental health: evidence, challenges and future directions, K Bhui, J Newbury, R Latham, M Ucci, Z Nasar, B Turner, C O'Leary, HL Fisher, E Marczylo, P Douglas, S Stansfeld, S Jackson, S Tyrrel, A Rzhetsky, R Kinnersley, P Kumar, C Duchaine, and F Coulon

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Impact of growth media and pressure on the diversity and antimicrobial activity of isolates from two species of hexactinellid sponge, Matthew J. Koch, Poppy J. Hesketh-Best, Gary Smerdon, Philip J. Warburton, Kerry Howell, and Mathew Upton

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Single-Cell Regulatory Network Inference and Clustering Identifies Cell-Type Specific Expression Pattern of Transcription Factors in Mouse Sciatic Nerve, Mingchao Li, Qing Min, Matthew C. Banton, and Xinpeng Dun

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UK B.1.1.7 (Alpha) variant exhibits increased respiratory replication and shedding in nonhuman primates, Kyle Rosenke, F Feldmann, Atsushi Okumura, Frederick Hansen, Tsing Lee Tang-Huau, Kimberly Meade-White, Benjamin Kaza, Julie Callison, Matthew C. Lewis, Brian J. Smith, Patrick W. Hanley, Jamie Lovaglio, Michael A. Jarvis, Carl Shaia, and H Feldmann

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Meta-Analysis Reveals Transcription Factor Upregulation in Cells of Injured Mouse Sciatic Nerve, Mingchao Li, Matthew C. Banton, Qing Min, David B. Parkinson, and Xinpeng Dun

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Plasmid fitness costs are caused by specific genetic conflicts enabling resolution by compensatory mutation, JPJ Hall, RCT Wright, E Harrison, KJ Muddiman, AJ Wood, S Paterson, and MA Brockhurst

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Forward and Reverse Genetics of B Cell Malignancies: From Insertional Mutagenesis to CRISPR-Cas, Joanna C. Dawes and Anthony G. Uren

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Respiratory Parameters for the Classification of Dysfunctional Insulin Secretion by Pancreatic Islets, Uma D. Kabra, Charles Affourtit, and Martin Jastroch

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UK B.1.1.7 variant exhibits increased respiratory replication and shedding in nonhuman primates, K Rosenke, F Feldmann, A Okumura, F Hansen, T Tang-Huau, K Meade-White, B Kaza, BJ Smith, PW Hanley, J Lovaglio, MA Jarvis, C Shaia, and H Feldmann

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Editorial: Bacteriocins and Other Ribosomally Synthesised and Post-translationally Modified Peptides (RiPPs) as Alternatives to Antibiotics, Harsh Mathur, Des Field, Mathew Upton, and Paul D. Cotter

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Study the influence of waxy wheat flour, inulin and guar gum on quality and microstructure of Pita and Tandoori breads: response surface methodology aids functional food development, Yaseen Galali, Gail Rees, and Victor Kuri

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Effect of methionine feeding on oxidative stress, intracellular calcium and contractility in cardiomyocytes isolated from male and female rats, Shatha A. Demerchi, Nicola King, James R. McFarlane, and Pierre D.J. Moens

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Mastomys natalensis Has a Cellular Immune Response Profile Distinct from Laboratory Mice, Tsing Lee Tang-Huau, Kyle Rosenke, Kimberly Meade-White, Aaron Carmody, Brian J. Smith, Catharine M. Bosio, Michael A. Jarvis, and Heinz Feldmann

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Orally delivered MK-4482 inhibits SARS-CoV-2 replication in the Syrian hamster model, K Rosenke, Frederick Hansen, Benjamin Schwarz, F Feldmann, Elaine Haddock, R Rosenke, Kent Barbian, Kimberly Meade-White, Atsushi Okumura, Shanna Leventhal, David W. Hawman, Emily Ricotta, Catharine M. Bosio, Craig Martens, Greg Saturday, H Feldmann, and Michael A. Jarvis

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Lassa Virus Treatment Options, Frederick Hansen, Michael A. Jarvis, Heinz Feldmann, and Kyle Rosenke

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HTK versus multidose cardioplegias for myocardial protection in adult cardiac surgery: A meta‐analysis, Alexander C. Reynolds, Sanjay Asopa, Amit Modi, and Nicola King

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Single Cell Transcriptome Data Analysis Defines the Heterogeneity of Peripheral Nerve Cells in Homeostasis and Regeneration, Bing Chen, Matthew C. Banton, Lolita Singh, David B. Parkinson, and Xin Peng Dun

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Drug repurposing for next-generation combination therapies against multidrug-resistant bacteria, Yuan Liu, Ziwen Tong, Jingru Shi, Ruichao Li, Mathew Upton, and Zhiqiang Wang

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Targeting Ebola virus replication through pharmaceutical intervention, Frederick Hansen, Heinz Feldmann, and Michael A. Jarvis

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Bridging the gap: Using reservoir ecology and human serosurveys to estimate Lassa virus spillover in West Africa, Andrew J. Basinski, Elisabeth Fichet-Calvet, Anna R. Sjodin, Tanner J. Varrelman, Christopher H. Remien, Nathan C. Layman, Brian H. Bird, David J. Wolking, Corina Monagin, Bruno M. Ghersi, Peter A. Barry, Michael A. Jarvis, Paul E. Gessler, and Scott L. Nuismer

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The relationship between gestational weight gain, maternal upper-body subcutaneous fat changes and infant birth size: a pilot observational study amongst women with obesity, Kathy M. Redfern, Heidi J. Hollands, Joanne Hosking, C. Ross Welch, Jonathan H. Pinkney, and Gail A. Rees

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Fat mass prediction equations and reference ranges for Saudi Arabian Children aged 8–12 years using machine technique method, RB Alkutbe, A Alruban, H Alturki, A Sattar, H Al-Hazzaa, and G Rees

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Variability in carbapenemase activity of intrinsic OxaAb (OXA-51-like) β-lactamase enzymes in Acinetobacter baumannii., Yuiko Takebayashi, Jacqueline Findlay, Kate J. Heesom, Philip J. Warburton, Matthew B. Avison, and Benjamin A. Evans

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The Phylogenetic Structure of Reptile, Avian and Uropathogenic Escherichia coli with Particular Reference to Extraintestinal Pathotypes, Marta Książczyk, Bartłomiej Dudek, Maciej Kuczkowski, Robert O’Hara, Kamila Korzekwa, Anna Wzorek, Agnieszka Korzeniowska-Kowal, Mathew Upton, Adam Junka, Alina Wieliczko, Radosław Ratajszczak, and Gabriela Bugla-Płoskońska

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Effect of ageing and hypertension on the expression and activity of PEPT2 in normal and hypertrophic hearts, Othman Alghamdi, Nicola King, Graham L. Jones, and Pierre D.J. Moens

Submissions from 2020

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Defining the Syrian hamster as a highly susceptible preclinical model for SARS-CoV-2 infection, Kyle Rosenke, Kimberly Meade-White, Michael Letko, Chad Clancy, Frederick Hansen, Yanan Liu, Atsushi Okumura, Tsing Lee Tang-Huau, Rong Li, Greg Saturday, F Feldmann, Dana Scott, Zhongde Wang, Vincent Munster, Michael A. Jarvis, and H Feldmann

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A rapid response vaccine development strategy for newcastle disease in poultry, SR R. Maremagae, CC C. Bezuidenhout, AM M. Murphy, MA A. Jarvis, P Naicker, and P. J. Lebea

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Hydroxychloroquine prophylaxis and treatment is ineffective in macaque and hamster SARS-CoV-2 disease models, Kyle Rosenke, Michael A. Jarvis, F Feldmann, Benjamin Schwarz, Atsushi Okumura, Jamie Lovaglio, Greg Saturday, Patrick W. Hanley, Kimberly Meade-White, Brandi N. Williamson, Frederick Hansen, L Pérez-Pérez, Shanna Leventhal, Tsing Lee Tang-Huau, Julie Callison, Elaine Haddock, Kaitlin A. Stromberg, Graham Sewell, Dana Scott, Catharine M. Bosio, David Hawman, Wit E de, and H Feldmann

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Characterising a human endogenous retrovirus(HERV)-derived tumour-associated antigen: enriched RNA-Seq analysis of HERV-K(HML-2) in mantle cell lymphoma cell lines, Witold Tatkiewicz, James Dickie, Franchesca Bedford, Alexander Jones, Mark Atkin, Michele Kiernan, Emmanuel Atangana Maze, Bora Agit, Garry Farnham, Alexander Kanapin, and Robert Belshaw

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Next-generation sequencing of 35 RHD variants in 16 253 serologically D− pregnant women in the Finnish population, Silja M. Tammi, Wajnat A. Tounsi, Susanna Sainio, Michele Kiernan, Neil D. Avent, Tracey E. Madgett, and Katri Haimila

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Microplegia in cardiac surgery: Systematic review and meta‐analysis, Claire M. Owen, Sanjay Asopa, Neil A. Smart, and Nicola King

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Multiple DNA viruses identified in multimammate mouse (Mastomys natalensis) populations from across regions of sub-Saharan Africa, Sébastien Calvignac-Spencer, Léonce Kouadio, Emmanuel Couacy-Hymann, Nafomon Sogoba, Kyle Rosenke, Andrew J. Davison, Fabian Leendertz, Michael A. Jarvis, Heinz Feldmann, and Bernhard Ehlers

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Modulation of Rab7a-mediated growth factor receptor trafficking inhibits islet beta cell apoptosis and autophagy under conditions of metabolic stress, Nirun V. Hewawasam, Fadel Lhaf, Henry A. Taylor, Katrina Viloria, Amazon Austin, Aileen King, P Jones, L Jones, Mark D. Turner, and Natasha J. Hill

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Bayesian estimation of Lassa virus epidemiological parameters: Implications for spillover prevention using wildlife vaccination, Scott L. Nuismer, Christopher H. Remien, Andrew J. Basinski, Tanner Varrelman, Nathan Layman, Kyle Rosenke, Brian Bird, Michael Jarvis, Peter Barry, Patrick W. Hanley, and Elisabeth Fichet-Calvet

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Plasmodium berghei LAPs form an extended protein complex that facilitates crystalloid targeting and biogenesis, Annie Z. Tremp, Sadia Saeed, Vikram Sharma, Edwin Lasonder, and Johannes T. Dessens

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Evaluation of drugs for potential repurposing against COVID-19 using a tier-based scoring system, Michael A. Jarvis, Frederick A. Hansen, Kyle Rosenke, Elaine Haddock, Christopher Rollinson, Simon Rule, Graham Sewell, Andrew Hughes, and Heinz Feldmann

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Flowering poration – a synergistic multi-mode antibacterial mechanism by a bacteriocin fold, Katharine Hammond, Helen Lewis, Samantha Halliwell, Florie Desriac, Brunello Nardone, Jascindra Ravi, Bart W. Hoogenboom, Mathew Upton, Jeremy P. Derrick, and Maxim G. Ryadnov

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The Aspergillus fumigatus transcription factor RglT is important for gliotoxin biosynthesis and self-protection, and virulence, Laure N.A. Ries, Lakhansing Pardeshi, Zhiqiang Dong, Kaeling Tan, Jacob L. Steenwyk, Ana Cristina Colabardini, Filho JA Ferreira, Castro PA de, Lilian P. Silva, Nycolas W. Preite, Fausto Almeida, Assis LJ de, Santos RAC dos, Paul Bowyer, Michael Bromley, Rebecca A. Owens, Sean Doyle, Marilene Demasi, Diego C.R. Hernández, Luís Eduardo S. Netto, Monica T. Pupo, Antonis Rokas, Flavio V. Loures, Koon H. Wong, and Gustavo H. Goldman

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Test–retest reliability of pulmonary oxygen uptake and muscle deoxygenation during moderate- and heavy-intensity cycling in youth elite-cyclists, A Nimmerichter, BC Breese, B Prinz, M Zoeger, C Rumpl, and CA Williams

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Rethinking animal models of sepsis – working towards improved clinical translation whilst integrating the 3Rs, Manasi Nandi, Simon K. Jackson, Duncan Macrae, Manu Shankar-Hari, Jordi L. Tremoleda, and Elliot Lilley

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Lysophosphatidylcholine acyltransferase 2 (LPCAT2) co-localises with TLR4 and regulates macrophage inflammatory gene expression in response to LPS, W. Abate, H. Alrammah, M. Kiernan, A. J. Tonks, and S. K. Jackson

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Ubiquitin activation is essential for schizont maturation in Plasmodium falciparum blood-stage development, Judith L. Green, Yang Wu, Vesela Encheva, Edwin Lasonder, Adchara Prommaban, Simone Kunzelmann, Evangelos Christodoulou, Munira Grainger, Ngoc Truongvan, Sebastian Bothe, Vikram Sharma, Wei Song, Irene Pinzuti, Chairat Uthaipibull, Somdet Srichairatanakool, Veronique Birault, Gordon Langsley, Hermann Schindelin, Benjamin Stieglitz, Ambrosius P. Snijders, and Anthony A. Holder

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Genomics–Metabolomics Profiling Disclosed Marine Vibrio spartinae 3.6 as a Producer of a New Branched Side Chain Prodigiosin, Giovanni Andrea Vitale, Martina Sciarretta, Esposito F Palma, Grant Garren January, Marianna Giaccio, Boyke Bunk, Cathrin Spröer, Felizitas Bajerski, Deborah Power, Carmen Festa, Maria Chiara Monti, MV D’Auria, and Pascale D de

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Influence of muscle oxygenation and nitrate-rich beetroot juice supplementation on o2 uptake kinetics and exercise tolerance, S Cocksedge, B Breese, P Morgan, L Nogueira, C Thompson, L Wylie, A Jones, and S Bailey

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Vesiculation of Red Blood Cells in the Blood Bank: A Multi-Omics Approach towards Identification of Causes and Consequences, Leal JK Freitas, Edwin Lasonder, Vikram Sharma, Jürgen Schiller, Giuseppina Fanelli, Sara Rinalducci, Roland Brock, and Giel Bosman

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Effect of L-Methionine Feeding on Serum Homocysteine and Glutathione Levels in Male and Female Wistar Rats, Demerchi S. Ahmad, McFarlane J Robert, Jean Moens P Dominique, and N King

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Nutrient Extraction Lowers Postprandial Glucose Response of Fruit in Adults with Obesity as well as Healthy Weight Adults, Rabab Alkutbe, Kathy Redfern, Michael Jarvis, and Gail Rees

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A Novel Lactic Acid Bacteria Mixture: Macrophage-Targeted Prophylactic Intervention in Colorectal Cancer Management, Petra Hradicka, Jane Beal, Monika Kassayova, Andrew Foey, and Vlasta Demeckova

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NAD (P) transhydrogenase has vital non‐mitochondrial functions in malaria parasite transmission, Sadia Saeed, Annie Z. Tremp, Vikram Sharma, Edwin Lasonder, and Johannes T. Dessens