Browse research from the School of Biomedical Sciences.

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Submissions from 2016

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Cytomegalovirus-based vaccine expressing Ebola virus glycoprotein protects nonhuman primates from Ebola virus infection, Andrea Marzi, Aisling A. Murphy, F Feldmann, Christopher J. Parkins, Elaine Haddock, Patrick W. Hanley, Matthew J. Emery, Flora Engelmann, Ilhem Messaoudi, H Feldmann, and Michael A. Jarvis

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Palmitate-induced impairment of glucose-stimulated insulin secretion precedes mitochondrial dysfunction in mouse pancreatic islets, Jonathan Barlow, Verena Hirschberg Jensen, Martin Jastroch, and Charles Affourtit

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Self-disseminating vaccines for emerging infectious diseases, Aisling A. Murphy, Alec J. Redwood, and Michael A. Jarvis

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Identification of an antibacterial protein by functional screening of a human oral metagenomic library, Preeti Arivaradarajan, Philip J. Warburton, Gunasekaran Paramasamy, Sean P. Nair, Elaine Allan, and Peter Mullany

Submissions from 2015

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Lineage-Specific Methyltransferases Define the Methylome of the Globally Disseminated Escherichia coli ST131 Clone, Brian M. Forde, Minh Duy Phan, Jayde A. Gawthorne, Melinda M. Ashcroft, Mitchell Stanton-Cook, Sohinee Sarkar, Kate M. Peters, Kok Gan Chan, Teik Min Chong, Wai Fong Yin, Mathew Upton, Mark A. Schembri, and Scott A. Beatson

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Genetic identification of cytomegaloviruses in a rural population of Côte d’Ivoire, Augustin Etile Anoh, Chantal Akoua-Koffi, Emmanuel Couacy-Hymann, Maude Pauly, Grit Schubert, Arsène Mossoun, Sabrina Weiss, SAJ Leendertz, Michael A. Jarvis, FH Leendertz, and Bernhard Ehlers

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The expression of Toll-like receptor 4, 7 and co-receptors in neurochemical sub-populations of rat trigeminal ganglion sensory neurons, M. P. Helley, W. Abate, S. K. Jackson, J. H. Bennett, and S. W.N. Thompson

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Fetal Sex and RHD Genotyping with Digital PCR Demonstrates Greater Sensitivity than Real-time PCR, Kelly A. Sillence, Llinos A. Roberts, Heidi J. Hollands, Hannah P. Thompson, Michele Kiernan, Tracey E. Madgett, Welch C Ross, and Neil D. Avent

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Fast, Ultrasensitive Detection of Reactive Oxygen Species Using a Carbon Nanotube Based-Electrocatalytic Intracellular Sensor, Frankie J. Rawson, Jacqueline Hicks, Nicholas Dodd, Wondwossen Abate, David J. Garrett, Nga Yip, Gyorgy Fejer, Alison J. Downard, Kim H.R. Baronian, Simon K. Jackson, and Paula M. Mendes

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Antibiotic-resistant ST38, ST131 and ST405 strains are the leading uropathogenic Escherichia coli clones in Riyadh, Saudi Arabia., Majed F. Alghoribi, Tarek M. Gibreel, Garry Farnham, Johani SM Al, Hanan H. Balkhy, and Mathew Upton

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On the mechanism by which dietary nitrate improves human skeletal muscle function, Charles Affourtit, Stephen J. Bailey, Andrew M. Jones, Miranda J. Smallwood, and Paul G. Winyard

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Novel Human Embryonic Stem Cell Regulators Identified by Conserved and Distinct CpG Island Methylation State, Steve Pells, Eirini Koutsouraki, Sofia Morfopoulou, Sara Valencia-Cadavid, Simon R. Tomlinson, Ravi Kalathur, Matthias E. Futschik, and Sousa PA De

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StemChecker: a web-based tool to discover and explore stemness signatures in gene sets, José P. Pinto, Ravi K. Kalathur, Daniel V. Oliveira, Tânia Barata, RSR Machado, S Machado, Ivette Pacheco-Leyva, Isabel Duarte, and Matthias E. Futschik

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Third-generation cephalosporin resistance conferred by a chromosomally encoded blaCMY-23 gene in the Escherichia coli ST131 reference strain EC958., Minh Duy Phan, Kate M. Peters, Sohinee Sarkar, Brian M. Forde, Alvin W. Lo, Mitchell Stanton-Cook, Leah W. Roberts, Mathew Upton, Scott A. Beatson, and Mark A. Schembri

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Discovery of a polyomavirus in European badgers (Meles meles) and the evolution of host range in the family Polyomaviridae, Sarah C. Hill, Aisling A. Murphy, Matthew Cotten, Anne L. Palser, Phillip Benson, Sandrine Lesellier, Eamonn Gormley, Céline Richomme, Sylvia Grierson, Deirdre Ni Bhuachalla, Mark Chambers, Paul Kellam, María Laura Boschiroli, Bernhard Ehlers, Michael A. Jarvis, and Oliver G. Pybus

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Mitochondrialuncouplingprotein-2isnotinvolvedin palmitate-induced impairmentofglucose-stimulatedinsulinsecretion in INS-1Einsulinomacellsandisnotneededfortheamplification of insulin release, jensen V. hirschberg and Charles Affourtit

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Hyperbaric oxygen therapy accelerates osteoblast differentiation and promotes bone formation, H Al-Hadi, G Smerdon, and SW Fox

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Molecular characterization of a multidrug resistance IncF plasmid from the globally disseminated Escherichia coli ST131 clone., Minh Duy Phan, Brian M. Forde, Kate M. Peters, Sohinee Sarkar, Steven Hancock, Mitchell Stanton-Cook, Zakour NL Ben, Mathew Upton, Scott A. Beatson, and Mark A. Schembri

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Palmitate-induced impairment of glucose-stimulated insulin secretion by pancreatic beta cells is disconnected from concomitant mitochondrial respiratory defects, C Affourtit, J Barlow, VH Jensen, and M Jastroch

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Uncoupling protein-2 attenuates palmitoleate protection against the cytotoxic production of mitochondrial reactive oxygen species in INS-1E insulinoma cells., Jonathan Barlow, Jensen V Hirschberg, and Charles Affourtit

Submissions from 2014

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A novel phosphatidylinositol 3-kinase (PI3K) inhibitor directs a potent FOXO-dependent, p53-independent cell cycle arrest phenotype characterized by the differential induction of a subset of FOXO-regulated genes, Richard Hill, Ravi Kiran Reddy Kalathur, Sergio Callejas, Laura Colaço, Ricardo Brandão, Beatriz Serelde, Antonio Cebriá, Carmen Blanco-Aparicio, Joaquín Pastor, Matthias Futschik, Ana Dopazo, and Wolfgang Link

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Heat-killed probiotic bacteria differentially regulate colonic epithelial cell production of human β-defensin-2: dependence on inflammatory cytokines., N. Habil, W. Abate, J. Beal, and A. D. Foey

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Human cytomegalovirus-encoded pUL7 is a novel CEACAM1-like molecule responsible for promotion of angiogenesis., Jason D. Macmaniman, Andrew Meuser, Sara Botto, Patricia P. Smith, Fenyong Liu, Michael A. Jarvis, Jay A. Nelson, and Patrizia Caposio

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Multiple metabolomics of uropathogenic E. coli reveal different information content in terms of metabolic potential compared to virulence factors., Haitham AlRabiah, Yun Xu, Nicholas J.W. Rattray, Andrew A. Vaughan, Tarek Gibreel, Ali Sayqal, Mathew Upton, J. William Allwood, and Royston Goodacre

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Toward a systems-level understanding of gene regulatory, protein interaction, and metabolic networks in cyanobacteria, MA Hernández-Prieto, Trudi A. Semeniuk, and Matthias E. Futschik

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StemCellNet: an interactive platform for network-oriented investigations in stem cell biology, José P. Pinto, Kalathur RK Reddy, Rui S.R. Machado, Joana M. Xavier, José Bragança, and Matthias E. Futschik

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Targeting molecular networks for drug research, José P. Pinto, Rui S.R. Machado, Joana M. Xavier, and Matthias E. Futschik

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Implementation of Fourier transform infrared spectroscopy for the rapid typing of uropathogenic Escherichia coli., S. E. Dawson, T. Gibreel, N. Nicolaou, H. AlRabiah, Y. Xu, R. Goodacre, and M. Upton

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The bacterial skin microbiome in psoriatic arthritis, an unexplored link in pathogenesis: challenges and opportunities offered by recent technological advances., Madhura Castelino, Stephen Eyre, Mathew Upton, Pauline Ho, and Anne Barton

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Global dissemination of a multidrug resistant Escherichia coli clone., Nicola K. Petty, Zakour NL Ben, Mitchell Stanton-Cook, Elizabeth Skippington, Makrina Totsika, Brian M. Forde, Minh Duy Phan, Moriel D Gomes, Kate M. Peters, Mark Davies, Benjamin A. Rogers, Gordon Dougan, Jesüs Rodriguez-Baño, Alvaro Pascual, Johann D.D. Pitout, Mathew Upton, David L. Paterson, Timothy R. Walsh, Mark A. Schembri, and Scott A. Beatson

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Rab8 Binding to Immune Cell-Specific Adaptor LAX Facilitates Formation of trans-Golgi Network-Proximal CTLA-4 Vesicles for Surface Expression, MC Banton, KL Inder, E Valk, CE Rudd, and H Schneider

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Insulin acutely improves mitochondrial function of rat and human skeletal muscle by increasing coupling efficiency of oxidative phosphorylation., Raid B. Nisr and Charles Affourtit

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Application of Microarray and Functional-Based Screening Methods for the Detection of Antimicrobial Resistance Genes in the Microbiomes of Healthy Humans, Roderick M. Card, Philip J. Warburton, Nikki MacLaren, Peter Mullany, Elaine Allan, and Muna F. Anjum

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A workflow for bacterial metabolic fingerprinting and lipid profiling: application to Ciprofloxacin challenged Escherichia coli, J. William Allwood, Haitham AlRabiah, Elon Correa, Andrew Vaughan, Yun Xu, Mathew Upton, and Royston Goodacre

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Differentially Expressed MicroRNAs in Maternal Plasma for the Noninvasive Prenatal Diagnosis of Down Syndrome (Trisomy 21), J Kamhieh-Milz, Reham Fadl Hassan Moftah, Gürkan Bal, Matthias Futschik, Viktor Sterzer, Omid Khorramshahi, Martin Burow, Gundula Thiel, Annegret Stuke-Sontheimer, Rabih Chaoui, S Kamhieh-Milz, and Abdulgabar Salama

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Galleria mellonella infection model demonstrates high lethality of ST69 and ST127 uropathogenic E. coli., Majed F. Alghoribi, Tarek M. Gibreel, Andrew R. Dodgson, Scott A. Beatson, and Mathew Upton

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The complete genome sequence of Escherichia coli EC958: a high quality reference sequence for the globally disseminated multidrug resistant E. coli O25b:H4-ST131 clone., Brian M. Forde, Zakour NL Ben, Mitchell Stanton-Cook, Minh Duy Phan, Makrina Totsika, Kate M. Peters, Kok Gan Chan, Mark A. Schembri, Mathew Upton, and Scott A. Beatson

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UniHI 7: an enhanced database for retrieval and interactive analysis of human molecular interaction networks, Ravi Kiran Reddy Kalathur, José Pedro Pinto, Miguel A. Hernández-Prieto, Rui S.R. MacHado, Dulce Almeida, Gautam Chaurasia, and Matthias E. Futschik

Submissions from 2013

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Novel insights into pancreatic β-cell glucolipotoxicity from real-time functional analysis of mitochondrial energy metabolism in INS-1E insulinoma cells., Jonathan Barlow and Charles Affourtit

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International multicenter evaluation of the DiversiLab bacterial typing system for Escherichia coli and Klebsiella spp., Guido M. Voets, Hall MA Leverstein-van, Susanne Kolbe-Busch, der Zanden A van, Deirdre Church, Martin Kaase, Andrea Grisold, Mathew Upton, Elaine Cloutman-Green, Rafael Cantón, Alexander W. Friedrich, Ad C. Fluit, and DiversiLab Study Group

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The Serum Resistome of a Globally Disseminated Multidrug Resistant Uropathogenic Escherichia coli Clone, Minh Duy Phan, Kate M. Peters, Sohinee Sarkar, Samuel W. Lukowski, Luke P. Allsopp, Danilo Gomes Moriel, Maud E.S. Achard, Makrina Totsika, Vikki M. Marshall, Mathew Upton, Scott A. Beatson, and Mark A. Schembri

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A FimH inhibitor prevents acute bladder infection and treats chronic cystitis caused by multidrug-resistant uropathogenic Escherichia coli ST131., Makrina Totsika, Maria Kostakioti, Thomas J. Hannan, Mathew Upton, Scott A. Beatson, James W. Janetka, Scott J. Hultgren, and Mark A. Schembri

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Probiotics, prebiotics and immunomodulation of gut mucosal defences: homeostasis and immunopathology., Holly Hardy, Jennifer Harris, Eleanor Lyon, Jane Beal, and Andrew D. Foey

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Synthetic epidermicin NI01 can protect Galleria mellonella larvae from infection with Staphylococcus aureus, Tarek M. Gibreel and Mathew Upton

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Genome Sequence of Hydrothermal Arsenic-Respiring Bacterium Marinobacter santoriniensis NKSG1T., Kim M. Handley, Mathew Upton, Scott A. Beatson, Marina Héry, and Jonathan R. Lloyd

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Dynamic Circadian Protein–Protein Interaction Networks Predict Temporal Organization of Cellular Functions, Thomas Wallach, Katja Schellenberg, Bert Maier, Ravi Kiran Reddy Kalathur, Pablo Porras, Erich E. Wanker, Matthias E. Futschik, and Achim Kramer

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High-throughput phenotyping of uropathogenic E. coli isolates with Fourier transform infrared spectroscopy., Haitham Alrabiah, Elon Correa, Mathew Upton, and Royston Goodacre

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Macrophage subset sensitivity to endotoxin tolerisation by Porphyromonas gingivalis., Andrew D. Foey and St John Crean

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Novel Polyomaviruses of Nonhuman Primates: Genetic and Serological Predictors for the Existence of Multiple Unknown Polyomaviruses within the Human Population, Nelly Scuda, Nadege Freda Madinda, Chantal Akoua-Koffi, Edgard Valerie Adjogoua, Diana Wevers, Jörg Hofmann, Kenneth N. Cameron, SAJ Leendertz, Emmanuel Couacy-Hymann, Martha Robbins, Christophe Boesch, Michael A. Jarvis, Ugo Moens, Lawrence Mugisha, Sébastien Calvignac-Spencer, FH Leendertz, and Bernhard Ehlers

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Suppression of T cell-induced osteoclast formation, S Karieb and SW Fox

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Tailoring 3D Single-Walled Carbon Nanotubes Anchored to Indium Tin Oxide for Natural Cellular Uptake and Intracellular Sensing, F. J. Rawson, C. L. Yeung, S. K. Jackson, and P. M. Mendes

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TetAB(46), a predicted heterodimeric ABC transporter conferring tetracycline resistance in Streptococcus australis isolated from the oral cavity, Philip J. Warburton, Lena Ciric, Avigdor Lerner, Lorna A. Seville, Adam P. Roberts, Peter Mullany, and Elaine Allan

Submissions from 2012

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Huntington's Disease and its therapeutic target genes: a global functional profile based on the HD Research Crossroads database, Ravi Kiran R. Kalathur, Miguel A. Hernández-Prieto, and Matthias E. Futschik

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Iron Deprivation in Synechocystis : Inference of Pathways, Non-coding RNAs, and Regulatory Elements from Comprehensive Expression Profiling, Miguel A. Hernández-Prieto, Verena Schön, Jens Georg, Luísa Barreira, João Varela, Wolfgang R. Hess, and Matthias E. Futschik

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Lactobacillus casei strain Shirota selectively modulates macrophage subset cytokine production, N Habil, J Beal, and AD Foey

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Non Invasive Prenatal Diagnosis of Aneuploidy: Next Generation Sequencing or Fetal DNA Enrichment?, N. D. Avent, A. Webb, T. E. Madgett, T. Miran, K. Sillence, N. Kaushik, and M. Kiernan

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Zinc modifies the effect of phyto-oestrogens on osteoblast and osteoclast differentiation in vitro., S Karieb and SW Fox

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Escherichia coli-mediated impairment of ureteric contractility is uropathogenic E. coli specific., Rachel V. Floyd, Mathew Upton, Scott J. Hultgren, Susan Wray, Theodor V. Burdyga, and Craig Winstanley

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Underweight and overweight men have greater exercise-induced dyspnoea than normal weight men, MMF Subhan, SA Ali, SSI Bokhari, MN Khan, and HR Ahmad

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High metabolic potential may contribute to the success of ST131 uropathogenic Escherichia coli., Tarek M. Gibreel, Andrew R. Dodgson, John Cheesbrough, Frederick J. Bolton, Andrew J. Fox, and Mathew Upton

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Antimicrobial peptides as therapeutic agents., Mathew Upton, Paul Cotter, and John Tagg

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Increased water current induces micro-architectural changes to the vertebral bone of juvenile rainbow trout (Oncorhynchus mykiss), MAG Owen, B Eynon, S Woodgate, SJ Davies, and S Fox

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Oral health and pathology: a macrophage account., Rebecca Merry, Louise Belfield, Paul McArdle, Andrew McLennan, Stjohn Crean, and Andrew Foey

Submissions from 2011

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Butyrate regulation of distinct macrophage subsets: Opposing effects on M1 and M2 macrophages, AD Foey

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Probiotic bacterial strains differentially modulate macrophage cytokine production in a strain-dependent and cell subset-specific manner., N. Habil, W. Al-Murrani, J. Beal, and A. D. Foey

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Isolation of bacterial extrachromosomal DNA from human dental plaque associated with periodontal disease, using transposon-aided capture (TRACA), Philip J. Warburton, Elaine Allan, Stephanie Hunter, John Ward, Veronica Booth, William G. Wade, and Peter Mullany

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2D DIGE analysis of maternal plasma for potential biomarkers of Down Syndrome., Wendy E. Heywood, Tracey E. Madgett, Darrell Wang, Amanda Wallington, Julie Hogg, Kevin Mills, and Neil D. Avent

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Genetic Organisation, Mobility and Predicted Functions of Genes on Integrated, Mobile Genetic Elements in Sequenced Strains of Clostridium difficile, Michael S.M. Brouwer, Philip J. Warburton, Adam P. Roberts, Peter Mullany, and Elaine Allan

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Profound early control of highly pathogenic SIV by an effector memory T-cell vaccine., Scott G. Hansen, Julia C. Ford, Matthew S. Lewis, Abigail B. Ventura, Colette M. Hughes, Lia Coyne-Johnson, Nathan Whizin, Kelli Oswald, Rebecca Shoemaker, Tonya Swanson, Alfred W. Legasse, Maria J. Chiuchiolo, Christopher L. Parks, Michael K. Axthelm, Jay A. Nelson, Michael A. Jarvis, Michael Piatak, Jeffrey D. Lifson, and Louis J. Picker

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Uncoupling protein-2 attenuates glucose-stimulated insulin secretion in INS-1E insulinoma cells by lowering mitochondrial reactive oxygen species., Charles Affourtit, Martin Jastroch, and Martin D. Brand

Phytoestrogens directly inhibit TNF-α-induced bone resorption in RAW264.7 cells by suppressing c-fos-induced NFATc1 expression., S Karieb and SW Fox

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A Replicating Cytomegalovirus-Based Vaccine Encoding a Single Ebola Virus Nucleoprotein CTL Epitope Confers Protection against Ebola Virus, Yoshimi Tsuda, Patrizia Caposio, Christopher J. Parkins, Sara Botto, Ilhem Messaoudi, Luka Cicin-Sain, Heinz Feldmann, and Michael A. Jarvis

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Insights into a Multidrug Resistant Escherichia coli Pathogen of the Globally Disseminated ST131 Lineage: Genome Analysis and Virulence Mechanisms, Makrina Totsika, Scott A. Beatson, Sohinee Sarkar, P Minh-Duy, Nicola K. Petty, Nathan Bachmann, Marek Szubert, Hanna E. Sidjabat, David L. Paterson, Mathew Upton, and Mark A. Schembri

Submissions from 2010

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Expression profiling and cross-species RNA interference (RNAi) of desiccation-induced transcripts in the anhydrobiotic nematode Aphelenchus avenae, W Reardon, S Chakrabortee, TC Pereira, T Tyson, MC Banton, KM Dolan, BA Culleton, MJ Wise, AM Burnell, and A Tunnacliffe

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Mouse CD8alpha+ DCs and human BDCA3+ DCs are major producers of IFN-lambda in response to poly IC., Henning Lauterbach, Barbara Bathke, Stefanie Gilles, Claudia Traidl-Hoffmann, Christian A. Luber, György Fejer, Marina A. Freudenberg, Gayle M. Davey, David Vremec, Axel Kallies, Li Wu, Ken Shortman, Paul Chaplin, Mark Suter, Meredith O'Keeffe, and Hubertus Hochrein

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Biparental mucus feeding: a unique example of parental care in an Amazonian cichlid., Jonathan Buckley, Richard J. Maunder, Andrew Foey, Janet Pearce, Adalberto L. Val, and Katherine A. Sloman

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Comparison and consolidation of microarray data sets of human tissue expression, Jenny Russ and Matthias E. Futschik

Submissions from 2009

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A Novel Cre Recombinase Imaging System for Tracking Lymphotropic Virus Infection In Vivo, Bernadette M. Dutia, Stuart J. Reid, Derek D. Drummond, Yvonne Ligertwood, Ian Bennet, Willard Rietberg, Ondine Silvia, Michael A. Jarvis, and Anthony A. Nash

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Choreography of the Transcriptome, Photophysiology, and Cell Cycle of a Minimal Photoautotroph, Prochlorococcus, Erik R. Zinser, Debbie Lindell, Zackary I. Johnson, Matthias E. Futschik, Claudia Steglich, Maureen L. Coleman, Matthew A. Wright, Trent Rector, Robert Steen, Nathan McNulty, Luke R. Thompson, and Sallie W. Chisholm

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Effector memory T cell responses are associated with protection of rhesus monkeys from mucosal simian immunodeficiency virus challenge., Scott G. Hansen, Cassandra Vieville, Nathan Whizin, Lia Coyne-Johnson, Don C. Siess, Derek D. Drummond, Alfred W. Legasse, Michael K. Axthelm, Kelli Oswald, Charles M. Trubey, Michael Piatak, Jeffrey D. Lifson, Jay A. Nelson, Michael A. Jarvis, and Louis J. Picker

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Endotoxin emissions from commercial composting activities, Lewis Deacon, Louise Pankhurst, Jian Liu, Gillian H. Drew, Enda T. Hayes, Simon Jackson, J Longhurst, P Longhurst, Simon Pollard, and Sean Tyrrel

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UniHI 4: new tools for query, analysis and visualization of the human protein–protein interactome, Gautam Chaurasia, Soniya Malhotra, Jenny Russ, Sigrid Schnoegl, Christian Hänig, Erich E. Wanker, and Matthias E. Futschik

Submissions from 2008

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Key role of splenic myeloid DCs in the IFN-alphabeta response to adenoviruses in vivo., György Fejer, Lisa Drechsel, Jan Liese, Ulrike Schleicher, Zsolt Ruzsics, Nicola Imelli, Urs F. Greber, Simone Keck, Bernd Hildenbrand, Anne Krug, Christian Bogdan, and Marina A. Freudenberg

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Toll-like receptor and IL-12 signaling control susceptibility to contact hypersensitivity., Stefan F. Martin, Jan C. Dudda, Eva Bachtanian, Annalisa Lembo, Stefanie Liller, Christoph Dürr, Markus M. Heimesaat, Stefan Bereswill, György Fejer, Ralitsa Vassileva, Thilo Jakob, N Freudenberg, Christian C. Termeer, Caroline Johner, Chris Galanos, and MA Freudenberg

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The Challenge of Regulation in a Minimal Photoautotroph: Non-Coding RNAs in Prochlorococcus, Claudia Steglich, Matthias E. Futschik, Debbie Lindell, Bjoern Voss, Sallie W. Chisholm, and Wolfgang R. Hess

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Energization-dependent endogenous activation of proton conductance in skeletal muscle mitochondria., Nadeene Parker, Charles Affourtit, Antonio Vidal-Puig, and Martin D. Brand

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Transforming growth factor-beta enables NFATc1 expression during osteoclastogenesis., SW Fox, KE Evans, and AC Lovibond

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Resting CD4+ effector memory T cells are precursors of bystander-activated effectors: a surrogate model of rheumatoid arthritis synovial T-cell function., Fionula M. Brennan, Nicola M.G. Smith, Sally Owen, Ching Li, Parisa Amjadi, Patricia Green, Anna Andersson, Andrew C. Palfreeman, Philippa Hillyer, Andrew Foey, Jonathan T. Beech, and Marc Feldmann

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The two homologous chaperonin 60 proteins of Mycobacterium tuberculosis have distinct effects on monocyte differentiation into osteoclasts, VR Winrow, J Mesher, S Meghji, CJ Morris, M Maguire, S Fox, ARM Coates, P Tormay, DR Blake, and B Henderson

Submissions from 2007

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Interleukin-10 inhibits osteoclastogenesis by reducing NFATc1 expression and preventing its translocation to the nucleus., KE Evans and SW Fox

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UniHI: an entry gate to the human protein interactome, Gautam Chaurasia, Yasir Iqbal, Christian Hänig, Hanspeter Herzel, Erich E. Wanker, and Matthias E. Futschik

Submissions from 2005

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Current insights into the role of transforming growth factor-beta in bone resorption, SW Fox and AC Lovibond

Submissions from 2004

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Model selection and efficiency testing for normalization of cDNA microarray, Matthias Futschik and Toni Crompton

Submissions from 2003

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A longitudinal study of the effect of subcutaneous estrogen replacement on bone in young women with Turner's syndrome, G Khastgir, JWW Studd, SW Fox, J Jones, J aghband-Zadeh, and JWM Chow

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Impact of VIP and cAMP on the regulation of TNF-alpha and IL-10 production: implications for rheumatoid arthritis, AD Foey, S Field, S Ahmed, A Jain, M Feldmann, FM Brennan, and R Williams

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TGF-beta-induced SOCS3 expression augments TNF-alpha-induced osteoclast formation, AC Lovibond, SJ Haque, TJ Chambers, and SW Fox

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The possible role of TGF-beta-induced suppressors of cytokine signaling expression in osteoclast/macrophage lineage commitment in vitro, SW Fox, SJ Haque, AC Lovibond, and TJ Chambers

Submissions from 2002

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TNFα Potently Activates Osteoclasts, through a Direct Action Independent of and Strongly Synergistic with RANKL., K Fuller, C Murphy, S Fox, B Kirstein, and TJ Chambers

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Cytokine regulation in RA synovial tissue: role of T cell/macrophage contact-dependent interactions., Fionula Brennan and Andrew Foey

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Cytokine-stimulated T cells induce macrophage IL-10 production dependent on phosphatidylinositol 3-kinase and p70S6K: implications for rheumatoid arthritis, A Foey, P Green, B Foxwell, M Feldmann, and F Brennan