Browse research from the School of Biomedical Sciences.

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Submissions from 2023

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Urinary tract infections: a review of the current diagnostics landscape, Braith Grey, Mathew Upton, and Lovleen Tina Joshi

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Runx2 regulates peripheral nerve regeneration to promote Schwann cell migration and re-myelination, Rong Hu, Xinpeng Dun, Lolita Singh, and Matthew C. Banton

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An organotypic oral mucosal infection model to study host-pathogen interactions, Samantha J. Gould, Andrew D. Foey, and Vehid M. Salih

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Toll-like receptor 4 and macrophage scavenger receptor 1 crosstalk regulates phagocytosis of a fungal pathogen, Chinaemerem U. Onyishi, Guillaume E. Desanti, Alex L. Wilkinson, Samuel Lara-Reyna, Eva Maria Frickel, Gyorgy Fejer, Olivier D. Christophe, Clare E. Bryant, Subhankar Mukhopadhyay, Siamon Gordon, and Robin C. May

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Isolation and genome sequencing of cytomegaloviruses from Natal multimammate mice (Mastomys natalensis), Frederick Hansen, Matej Vučak, Jenna Nichols, Joseph Hughes, Sidy Bane, Salvatore Camiolo, Silva Filipe A da, Eleonore Ostermann, Laura Staliunaite, Baca Chan, Thekla Mauch, Nafomon Sogoba, Daniel N. Streblow, Sebastian Voigt, Lisa Oestereich, Bernhard Ehlers, Alec J. Redwood, Heinz Feldmann, Wolfram Brune, Kyle Rosenke, Michael A. Jarvis, and Andrew J. Davison

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An attenuated herpesvirus vectored vaccine candidate induces T-cell responses against highly conserved porcine reproductive and respiratory syndrome virus M and NSP5 proteins that are unable to control infection, Brito RCF de, Kerry Holtham, Jessica Roser, Jack E. Saunders, Yvonne Wezel, Summer Henderson, Thekla Mauch, Beatriz Sanz-Bernardo, Jean Pierre Frossard, Matthieu Bernard, Fabian Z.X. Lean, Alejandro Nunez, Simon Gubbins, Nicolás M. Suárez, Andrew J. Davison, Michael J. Francis, Michael Huether, Hafid Benchaoui, Jeremy Salt, Veronica L. Fowler, Michael A. Jarvis, and Simon P. Graham

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Calculation of ATP production rates using the Seahorse XF Analyzer, Brandon R. Desousa, Kristen K.O. Kim, Anthony E. Jones, Andréa B. Ball, Wei Y. Hsieh, Pamela Swain, Danielle H. Morrow, Alexandra J. Brownstein, David A. Ferrick, Orian S. Shirihai, Andrew Neilson, David A. Nathanson, George W. Rogers, Brian P. Dranka, Anne N. Murphy, Charles Affourtit, Steven J. Bensinger, Linsey Stiles, Natalia Romero, and Ajit S. Divakaruni

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RHD molecular analysis—from discovery to next generation sequencing, Tracey E. Madgett, Wajnat A. Tounsi, Amr J. Halawani, and Neil D. Avent

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A metabologenomics approach to unlock the metabolome of the novel Antarctic deep-sea isolate Lacinutrix shetlandiensis sp. nov. WUR7, Giovanni A. Vitale, Grant G. January, Ernest Oppong-Danquah, Sala G Della, Esposito F Palma, Deniz Tasdemir, and Pascale D de

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The Potential of Probiotics as Ingestible Adjuvants and Immune Modulators for Antiviral Immunity and Management of SARS-CoV-2 Infection and COVID-19, Sophie Tomkinson, Cloe Triscott, Emily Schenk, and Andrew Foey

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Air quality and mental health: evidence, challenges and future directions, Kamaldeep Bhui, Joanne B. Newbury, Rachel M. Latham, Marcella Ucci, Zaheer A. Nasir, Briony Turner, Catherine O'Leary, Helen L. Fisher, Emma Marczylo, Philippa Douglas, Stephen Stansfeld, Simon K. Jackson, Sean Tyrrel, Andrey Rzhetsky, Rob Kinnersley, Prashant Kumar, Caroline Duchaine, and Frederic Coulon

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Bovine Herpesvirus-4 Based Vaccine Provides Protective Immunity against Streptococcus suis Disease in a Rabbit Model, Nihua Dong, Hester Nichols, Q Sun, Xiaojun Chen, Jiayang Zheng, Zhixin Guan, Hailong Zhang, Andrew Davison, Yvonne Wezel, Z Li, B Li, Ke Liu, Donghua Shao, Yafeng Qiu, J Sun, X Li, Mathew Upton, Zhiyong Ma, Michael A. Jarvis, and Jianchao Wei

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What’s really down the hospital plughole?, J. Butler and M. Upton

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Genistein and coumestrol reduce MCF-7 breast cancer cell viability and inhibit markers of preferential metastasis, bone matrix attachment and tumor-induced osteoclastogenesis, Mezban S. Al-Thamiree and SW Fox

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Optimization of sniff nasal inspiratory pressure (SNIP) measurement methodology in healthy subjects., M Subhan

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Whole genomes of deep-sea sponge-associated bacteria exhibit high novel natural product potential, Poppy J. Hesketh-Best, Grant G. January, Matthew J. Koch, Philip J. Warburton, Kerry L. Howell, and Mathew Upton

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Subunit Vaccine Targeting Phosphate ABC Transporter ATP-Binding Protein, PstB, Provides Cross-Protection against Streptococcus suis Serotype 2, 7, and 9 in Mice, Zujie Yan, Xiaohui Yao, Ruyi Pan, Junjie Zhang, X Ma, Nihua Dong, Jianchao Wei, K Liu, Yafeng Qiu, Katie Sealey, Hester Nichols, Michael A. Jarvis, Mathew Upton, X Li, Z Ma, J Liu, and B Li

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Subunit Vaccine Targeting Phosphate ABC Transporter ATP-Binding Protein, PstB, Provides Cross-Protection against Streptococcus suis Serotype 2, 7, and 9 in Mice, Zujie Yan, Xiaohui Yao, Ruyi Pan, Junjie Zhang, X Ma, Nihua Dong, Jianchao Wei, K Liu, Yafeng Qiu, Katie Sealey, Hester Nichols, Michael A. Jarvis, Mathew Upton, X Li, Z Ma, J Liu, and B Li

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The effects of acute hypoxia on cognitive and cardiovascular parameters in healthy subjects, R Ravi and MMF Subhan

Submissions from 2022

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Combined molnupiravir-nirmatrelvir treatment improves the inhibitory effect on SARS-CoV-2 in macaques, Kyle Rosenke, Matt C. Lewis, F Feldmann, Eric Bohrnsen, Benjamin Schwarz, Atsushi Okumura, W. Forrest Bohler, Julie Callison, Carl Shaia, Catharine M. Bosio, Jamie Lovaglio, Greg Saturday, Michael A. Jarvis, and H Feldmann

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Endotoxin as a Marker for Water Quality, Anas A. Sattar, Christian R. Good, Margaux Saletes, João Brandão, and Simon K. Jackson

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Is penicillin allergy de-labelling about to find its place in UK antimicrobial stewardship strategy?, Neil Powell, Mathew Upton, Bridie Kent, Sarah Tonkin-Crine, and Jonathan Sandoe

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Supervised physical activity and the incidence of gestational diabetes mellitus: a systematic review and meta-analysis, G. Bennett, N. King, K. Redfern, and B. C. Breese

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Dietary Intakes of Folate, Vitamin D and Iodine during the First Trimester of Pregnancy and the Association between Supplement Use and Demographic Characteristics amongst White Caucasian Women Living with Obesity in the UK, Kathy M. Redfern, Heidi J. Hollands, C. Ross Welch, Jonathan H. Pinkney, and Gail A. Rees

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Metabolomics Profiling of Vitamin D Status in Relation to Dyslipidemia, Hanaa Mousa, Mohamed A. Elrayess, Ilhame Diboun, Simon K. Jackson, and Susu M. Zughaier

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OXA-66 structure and oligomerisation of OXAAb enzymes, Y Takebayashi, SR Henderson, DY Chirgadze, PJ Warburton, and BA Evans

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Nitrite lowers the oxygen cost of ATP supply in cultured skeletal muscle cells by stimulating the rate of glycolytic ATP synthesis, Anthony G. Wynne and Charles Affourtit

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Hypertension alters the function and expression profile of the peptide cotransporters PEPT1 and PEPT2 in the rodent renal proximal tubule, Othman A. Alghamdi, Nicola King, Nicholas M. Andronicos, Graham L. Jones, Belal Chami, Paul K. Witting, and Pierre D.J. Moens

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Possible Regulation of Toll-Like Receptor 4 By Lysine Acetylation Through LPCAT2 Activity in RAW264.7 Cells., Victory Ibigo Poloamina, Wondwossen Abate, Gyorgy Fejer, and Simon K. Jackson

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First Trimester Noninvasive Prenatal Diagnosis of Maternally Inherited Beta-Thalassemia Mutations, Tracey E. Madgett

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Molnupiravir inhibits SARS-CoV-2 variants including Omicron in the hamster model, K Rosenke, Atsushi Okumura, Matthew C. Lewis, F Feldmann, Kimberly Meade-White, W. Forrest Bohler, Amanda Griffin, R Rosenke, Carl Shaia, Michael A. Jarvis, and H Feldmann

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Acute bioenergetic insulin sensitivity of skeletal muscle cells: ATP-demand-provoked glycolysis contributes to stimulation of ATP supply, Rosie A. Donnell, Jane E. Carré, and Charles Affourtit

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Epstein-Barr Virus-Encoded BILF1 Orthologues From Porcine Lymphotropic Herpesviruses Display Common Molecular Functionality, Maša Mavri, Valentina Kubale, Daniel P. Depledge, Jianmin Zuo, Christene A. Huang, Judith Breuer, Milka Vrecl, Michael A. Jarvis, Eva Jarc Jovičić, Toni Petan, Bernhard Ehlers, Mette M. Rosenkilde, and Katja Spiess

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The Impact of Waxy Wheat Flour, Inulin and Guar Gum on Post-Prandial Glycaemic and Satiety Indices, Sensory Attributes and Shelf Life of Tandoori and Pita Breads, Yaseen Galali, Gail Rees, and Victor Kuri

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SARS-CoV-2 reinfection prevents acute respiratory disease in Syrian hamsters but not replication in the upper respiratory tract, Frederick Hansen, Kimberly Meade-White, Chad Clancy, R Rosenke, Atsushi Okumura, David W. Hawman, F Feldmann, Benjamin Kaza, Michael A. Jarvis, K Rosenke, and H Feldmann

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Three-Week Old Pigs Are Not Susceptible to Productive Infection with SARS-COV-2, Elaine Haddock, Julie Callison, Stephanie N. Seifert, Atsushi Okumura, Tsing Lee Tang-Huau, Shanna S. Leventhal, Matthew C. Lewis, Jamie Lovaglio, Patrick W. Hanley, Carl Shaia, David W. Hawman, Vincent J. Munster, Michael A. Jarvis, Juergen A. Richt, and Heinz Feldmann

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Do Micronutrient and Omega-3 Fatty Acid Supplements Affect Human Maternal Immunity during Pregnancy? A Scoping Review, G Rees, L Brough, GM Orsatti, A Lodge, and S Walker

Submissions from 2021

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Hospital sink traps as a potential source of the emerging multidrug-resistant pathogen Cupriavidus pauculus: characterization and draft genome sequence of strain MF1, James Butler, Sean D. Kelly, Katie J. Muddiman, Alexandros Besinis, and Mathew Upton

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Air quality and mental health: evidence, challenges and future directions, K Bhui, J Newbury, R Latham, M Ucci, Z Nasar, B Turner, C O'Leary, HL Fisher, E Marczylo, P Douglas, S Stansfeld, S Jackson, S Tyrrel, A Rzhetsky, R Kinnersley, P Kumar, C Duchaine, and F Coulon

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Impact of growth media and pressure on the diversity and antimicrobial activity of isolates from two species of hexactinellid sponge, Matthew J. Koch, Poppy J. Hesketh-Best, Gary Smerdon, Philip J. Warburton, Kerry Howell, and Mathew Upton

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Single-Cell Regulatory Network Inference and Clustering Identifies Cell-Type Specific Expression Pattern of Transcription Factors in Mouse Sciatic Nerve, Mingchao Li, Qing Min, Matthew C. Banton, and Xinpeng Dun

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UK B.1.1.7 (Alpha) variant exhibits increased respiratory replication and shedding in nonhuman primates, Kyle Rosenke, F Feldmann, Atsushi Okumura, Frederick Hansen, Tsing Lee Tang-Huau, Kimberly Meade-White, Benjamin Kaza, Julie Callison, Matthew C. Lewis, Brian J. Smith, Patrick W. Hanley, Jamie Lovaglio, Michael A. Jarvis, Carl Shaia, and H Feldmann

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Meta-Analysis Reveals Transcription Factor Upregulation in Cells of Injured Mouse Sciatic Nerve, Mingchao Li, Matthew C. Banton, Qing Min, David B. Parkinson, and Xinpeng Dun

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Plasmid fitness costs are caused by specific genetic conflicts enabling resolution by compensatory mutation, JPJ Hall, RCT Wright, E Harrison, KJ Muddiman, AJ Wood, S Paterson, and MA Brockhurst

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Forward and Reverse Genetics of B Cell Malignancies: From Insertional Mutagenesis to CRISPR-Cas, Joanna C. Dawes and Anthony G. Uren

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Respiratory Parameters for the Classification of Dysfunctional Insulin Secretion by Pancreatic Islets, Uma D. Kabra, Charles Affourtit, and Martin Jastroch

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UK B.1.1.7 variant exhibits increased respiratory replication and shedding in nonhuman primates, K Rosenke, F Feldmann, A Okumura, F Hansen, T Tang-Huau, K Meade-White, B Kaza, BJ Smith, PW Hanley, J Lovaglio, MA Jarvis, C Shaia, and H Feldmann

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Study the influence of waxy wheat flour, inulin and guar gum on quality and microstructure of Pita and Tandoori breads: response surface methodology aids functional food development, Yaseen Galali, Gail Rees, and Victor Kuri

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Editorial: Bacteriocins and Other Ribosomally Synthesised and Post-translationally Modified Peptides (RiPPs) as Alternatives to Antibiotics, Harsh Mathur, Des Field, Mathew Upton, and Paul D. Cotter

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Mastomys natalensis Has a Cellular Immune Response Profile Distinct from Laboratory Mice, Tsing Lee Tang-Huau, Kyle Rosenke, Kimberly Meade-White, Aaron Carmody, Brian J. Smith, Catharine M. Bosio, Michael A. Jarvis, and Heinz Feldmann

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Lassa Virus Treatment Options, Frederick Hansen, Michael A. Jarvis, Heinz Feldmann, and Kyle Rosenke

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Targeting Ebola virus replication through pharmaceutical intervention, Frederick Hansen, Heinz Feldmann, and Michael A. Jarvis

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Single Cell Transcriptome Data Analysis Defines the Heterogeneity of Peripheral Nerve Cells in Homeostasis and Regeneration, Bing Chen, Matthew C. Banton, Lolita Singh, David B. Parkinson, and Xin Peng Dun

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Orally delivered MK-4482 inhibits SARS-CoV-2 replication in the Syrian hamster model, K Rosenke, Frederick Hansen, Benjamin Schwarz, F Feldmann, Elaine Haddock, R Rosenke, Kent Barbian, Kimberly Meade-White, Atsushi Okumura, Shanna Leventhal, David W. Hawman, Emily Ricotta, Catharine M. Bosio, Craig Martens, Greg Saturday, H Feldmann, and Michael A. Jarvis

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Bridging the gap: Using reservoir ecology and human serosurveys to estimate Lassa virus spillover in West Africa, Andrew J. Basinski, Elisabeth Fichet-Calvet, Anna R. Sjodin, Tanner J. Varrelman, Christopher H. Remien, Nathan C. Layman, Brian H. Bird, David J. Wolking, Corina Monagin, Bruno M. Ghersi, Peter A. Barry, Michael A. Jarvis, Paul E. Gessler, and Scott L. Nuismer

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Drug repurposing for next-generation combination therapies against multidrug-resistant bacteria, Yuan Liu, Ziwen Tong, Jingru Shi, Ruichao Li, Mathew Upton, and Zhiqiang Wang

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HTK versus multidose cardioplegias for myocardial protection in adult cardiac surgery: A meta‐analysis, Alexander C. Reynolds, Sanjay Asopa, Amit Modi, and Nicola King

Submissions from 2020

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The relationship between gestational weight gain, maternal upper-body subcutaneous fat changes and infant birth size: a pilot observational study amongst women with obesity, Kathy M. Redfern, Heidi J. Hollands, Joanne Hosking, C. Ross Welch, Jonathan H. Pinkney, and Gail A. Rees

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Effect of ageing and hypertension on the expression and activity of PEPT2 in normal and hypertrophic hearts, Othman Alghamdi, Nicola King, Graham L. Jones, and Pierre D.J. Moens

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The Phylogenetic Structure of Reptile, Avian and Uropathogenic Escherichia coli with Particular Reference to Extraintestinal Pathotypes, Marta Książczyk, Bartłomiej Dudek, Maciej Kuczkowski, Robert O’Hara, Kamila Korzekwa, Anna Wzorek, Agnieszka Korzeniowska-Kowal, Mathew Upton, Adam Junka, Alina Wieliczko, Radosław Ratajszczak, and Gabriela Bugla-Płoskońska

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Fat mass prediction equations and reference ranges for Saudi Arabian Children aged 8–12 years using machine technique method, RB Alkutbe, A Alruban, H Alturki, A Sattar, H Al-Hazzaa, and G Rees

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Effect of methionine feeding on oxidative stress, intracellular calcium and contractility in cardiomyocytes isolated from male and female rats, Shatha A. Demerchi, Nicola King, James R. McFarlane, and Pierre D.J. Moens

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Defining the Syrian hamster as a highly susceptible preclinical model for SARS-CoV-2 infection, Kyle Rosenke, Kimberly Meade-White, Michael Letko, Chad Clancy, Frederick Hansen, Yanan Liu, Atsushi Okumura, Tsing Lee Tang-Huau, Rong Li, Greg Saturday, F Feldmann, Dana Scott, Zhongde Wang, Vincent Munster, Michael A. Jarvis, and H Feldmann

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Variability in carbapenemase activity of intrinsic OxaAb (OXA-51-like) β-lactamase enzymes in Acinetobacter baumannii., Yuiko Takebayashi, Jacqueline Findlay, Kate J. Heesom, Philip J. Warburton, Matthew B. Avison, and Benjamin A. Evans

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A rapid response vaccine development strategy for newcastle disease in poultry, SR R. Maremagae, CC C. Bezuidenhout, AM M. Murphy, MA A. Jarvis, P Naicker, and P. J. Lebea

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Hydroxychloroquine prophylaxis and treatment is ineffective in macaque and hamster SARS-CoV-2 disease models, Kyle Rosenke, Michael A. Jarvis, F Feldmann, Benjamin Schwarz, Atsushi Okumura, Jamie Lovaglio, Greg Saturday, Patrick W. Hanley, Kimberly Meade-White, Brandi N. Williamson, Frederick Hansen, L Pérez-Pérez, Shanna Leventhal, Tsing Lee Tang-Huau, Julie Callison, Elaine Haddock, Kaitlin A. Stromberg, Graham Sewell, Dana Scott, Catharine M. Bosio, David Hawman, Wit E de, and H Feldmann

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Modulation of Rab7a-mediated growth factor receptor trafficking inhibits islet beta cell apoptosis and autophagy under conditions of metabolic stress, Nirun V. Hewawasam, Fadel Lhaf, Henry A. Taylor, Katrina Viloria, Amazon Austin, Aileen King, P Jones, L Jones, Mark D. Turner, and Natasha J. Hill

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Microplegia in cardiac surgery: Systematic review and meta‐analysis, Claire M. Owen, Sanjay Asopa, Neil A. Smart, and Nicola King

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Next-generation sequencing of 35 RHD variants in 16 253 serologically D− pregnant women in the Finnish population, Silja M. Tammi, Wajnat A. Tounsi, Susanna Sainio, Michele Kiernan, Neil D. Avent, Tracey E. Madgett, and Katri Haimila

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Flowering poration – a synergistic multi-mode antibacterial mechanism by a bacteriocin fold, Katharine Hammond, Helen Lewis, Samantha Halliwell, Florie Desriac, Brunello Nardone, Jascindra Ravi, Bart W. Hoogenboom, Mathew Upton, Jeremy P. Derrick, and Maxim G. Ryadnov

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Plasmodium berghei LAPs form an extended protein complex that facilitates crystalloid targeting and biogenesis, Annie Z. Tremp, Sadia Saeed, Vikram Sharma, Edwin Lasonder, and Johannes T. Dessens

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Evaluation of drugs for potential repurposing against COVID-19 using a tier-based scoring system, Michael A. Jarvis, Frederick A. Hansen, Kyle Rosenke, Elaine Haddock, Christopher Rollinson, Simon Rule, Graham Sewell, Andrew Hughes, and Heinz Feldmann

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Bayesian estimation of Lassa virus epidemiological parameters: Implications for spillover prevention using wildlife vaccination, Scott L. Nuismer, Christopher H. Remien, Andrew J. Basinski, Tanner Varrelman, Nathan Layman, Kyle Rosenke, Brian Bird, Michael Jarvis, Peter Barry, Patrick W. Hanley, and Elisabeth Fichet-Calvet

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Rethinking animal models of sepsis – working towards improved clinical translation whilst integrating the 3Rs, Manasi Nandi, Simon K. Jackson, Duncan Macrae, Manu Shankar-Hari, Jordi L. Tremoleda, and Elliot Lilley

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Test–retest reliability of pulmonary oxygen uptake and muscle deoxygenation during moderate- and heavy-intensity cycling in youth elite-cyclists, A Nimmerichter, BC Breese, B Prinz, M Zoeger, C Rumpl, and CA Williams

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Multiple DNA viruses identified in multimammate mouse (Mastomys natalensis) populations from across regions of sub-Saharan Africa, Sébastien Calvignac-Spencer, Léonce Kouadio, Emmanuel Couacy-Hymann, Nafomon Sogoba, Kyle Rosenke, Andrew J. Davison, Fabian Leendertz, Michael A. Jarvis, Heinz Feldmann, and Bernhard Ehlers

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Ubiquitin activation is essential for schizont maturation in Plasmodium falciparum blood-stage development, Judith L. Green, Yang Wu, Vesela Encheva, Edwin Lasonder, Adchara Prommaban, Simone Kunzelmann, Evangelos Christodoulou, Munira Grainger, Ngoc Truongvan, Sebastian Bothe, Vikram Sharma, Wei Song, Irene Pinzuti, Chairat Uthaipibull, Somdet Srichairatanakool, Veronique Birault, Gordon Langsley, Hermann Schindelin, Benjamin Stieglitz, Ambrosius P. Snijders, and Anthony A. Holder

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Lysophosphatidylcholine acyltransferase 2 (LPCAT2) co-localises with TLR4 and regulates macrophage inflammatory gene expression in response to LPS, W. Abate, H. Alrammah, M. Kiernan, A. J. Tonks, and S. K. Jackson

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Vesiculation of Red Blood Cells in the Blood Bank: A Multi-Omics Approach towards Identification of Causes and Consequences, Leal JK Freitas, Edwin Lasonder, Vikram Sharma, Jürgen Schiller, Giuseppina Fanelli, Sara Rinalducci, Roland Brock, and Giel Bosman

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Influence of muscle oxygenation and nitrate-rich beetroot juice supplementation on o2 uptake kinetics and exercise tolerance, S Cocksedge, B Breese, P Morgan, L Nogueira, C Thompson, L Wylie, A Jones, and S Bailey

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Genomics–Metabolomics Profiling Disclosed Marine Vibrio spartinae 3.6 as a Producer of a New Branched Side Chain Prodigiosin, Giovanni Andrea Vitale, Martina Sciarretta, Esposito F Palma, Grant Garren January, Marianna Giaccio, Boyke Bunk, Cathrin Spröer, Felizitas Bajerski, Deborah Power, Carmen Festa, Maria Chiara Monti, MV D’Auria, and Pascale D de

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Nutrient Extraction Lowers Postprandial Glucose Response of Fruit in Adults with Obesity as well as Healthy Weight Adults, Rabab Alkutbe, Kathy Redfern, Michael Jarvis, and Gail Rees

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A Novel Lactic Acid Bacteria Mixture: Macrophage-Targeted Prophylactic Intervention in Colorectal Cancer Management, Petra Hradicka, Jane Beal, Monika Kassayova, Andrew Foey, and Vlasta Demeckova

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Effect of L-Methionine Feeding on Serum Homocysteine and Glutathione Levels in Male and Female Wistar Rats, Demerchi S. Ahmad, McFarlane J Robert, Jean Moens P Dominique, and N King

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Purification and characterization of nisin P produced by a strain of Streptococcus gallolyticus, Abdu Aldarhami, Arif Felek, Vikram Sharma, and Mathew Upton

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Characterising a human endogenous retrovirus(HERV)-derived tumour-associated antigen: enriched RNA-Seq analysis of HERV-K(HML-2) in mantle cell lymphoma cell lines, Witold Tatkiewicz, James Dickie, Franchesca Bedford, Alexander Jones, Mark Atkin, Michele Kiernan, Emmanuel Atangana Maze, Bora Agit, Garry Farnham, Alexander Kanapin, and Robert Belshaw

Submissions from 2019

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NAD (P) transhydrogenase has vital non‐mitochondrial functions in malaria parasite transmission, Sadia Saeed, Annie Z. Tremp, Vikram Sharma, Edwin Lasonder, and Johannes T. Dessens

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Comparative analysis of total salivary lipopolysaccharide chemical and biological properties with periodontal status, Clare Mcilwaine, Alexander Strachan, Zoe Harrington, Matthew Jerreat, Louise A. Belfield, Viktor Sandor, Andrew Foey, and Svetislav Zaric

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Relationship between Initial High-Sensitivity Cardiac Troponin-T Morbidity and Mortality in Patients after ST-Elevation Myocardial Infarction in Erbil City, Iraq, HMH Ameen, MH Alwan, and N King

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Oropouche virus cases identified in Ecuador using an optimised qRT-PCR informed by metagenomic sequencing, Emma L. Wise, Sully Márquez, Jack Mellors, Verónica Paz, Barry Atkinson, Bernardo Gutierrez, Sonia Zapata, Josefina Coloma, Oliver G. Pybus, Simon K. Jackson, Gabriel Trueba, Gyorgy Fejer, Christopher H. Logue, and Steven T. Pullan

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Time-resolved characterization of the mechanisms of toxicity induced by silica and amino-modified polystyrene on alveolar-like macrophages, Sarah Deville, Birgit Honrath, Quynh T.D. Tran, Gyorgy Fejer, Ivo Lambrichts, Inge Nelissen, Amalia M. Dolga, and Anna Salvati

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Relationship between (non)linear phase II pulmonary oxygen uptake kinetics with skeletal muscle oxygenation and age in 11 to 15 y olds, BC Breese, ZL Saynor, AR Barker, N Armstrong, and CA Williams

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Effect of vitamin D supplementation on endothelial function – An updated systematic review with meta-analysis and meta-regression, Nick L. Pincombe, Melissa J. Pearson, Neil A. Smart, Nicola King, and Gudrun Dieberg

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Use of an Outbred Rat Hepacivirus Challenge Model for Design and Evaluation of Efficacy of Different Immunization Strategies for Hepatitis C Virus, Erwan Atcheson, Wenqin Li, Carly M. Bliss, Senthil Chinnakannan, Kathrin Heim, Hannah Sharpe, Claire Hutchings, Isabelle Dietrich, Dung Nguyen, Amit Kapoor, Michael A. Jarvis, Paul Klenerman, Eleanor Barnes, and Peter Simmonds

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Post-exercise hypotension and skeletal muscle oxygenation is regulated by nitrate-reducing activity of oral bacteria, C. Cutler, M. Kiernan, J. R. Willis, L. Gallardo-Alfaro, P. Casas-Agustench, D. White, M. Hickson, T. Gabaldon, and R. Bescos

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Cytomegalovirus distribution and evolution in hominines, Sripriya Murthy, K O’Brien, Anthony Agbor, Samuel Angedakin, Mimi Arandjelovic, Emmanuel Ayuk Ayimisin, Emma Bailey, Richard A. Bergl, Gregory Brazzola, Paula Dieguez, Manasseh Eno-Nku, Henk Eshuis, Barbara Fruth, Thomas R. Gillespie, Yisa Ginath, Maryke Gray, Ilka Herbinger, Sorrel Jones, Laura Kehoe, Hjalmar Kühl, Deo Kujirakwinja, Kevin Lee, Nadège F. Madinda, Guillain Mitamba, Emmanuel Muhindo, Radar Nishuli, Lucy J. Ormsby, Klara J. Petrzelkova, Andrew J. Plumptre, Martha M. Robbins, Volker Sommer, Heegde M Ter, Angelique Todd, Raymond Tokunda, Erin Wessling, Michael A. Jarvis, Fabian H. Leendertz, Bernhard Ehlers, and Sébastien Calvignac-Spencer

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Antagonistic Interactions between Benzo[a]pyrene and Fullerene (C60) in Toxicological Response of Marine Mussels, Audrey Barranger, Laura M. Langan, Vikram Sharma, Graham A. Rance, Yann Aminot, Nicola J. Weston, Farida Akcha, Michael N. Moore, Volker M. Arlt, Andrei N. Khlobystov, James W. Readman, and Awadhesh N. Jha

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Biocide Resistance and Transmission of Clostridium difficile Spores Spiked onto Clinical Surfaces from an American Health Care Facility, Calie Dyer, Lee P. Hutt, Robert Burky, and Lovleen Tina Joshi

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Mitochondrial Activity and Skeletal Muscle Insulin Resistance in Kidney Disease, Jane E. Carré and C Affourtit

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Assessing methodologies for fucoidan extraction from South African brown algae, GG January, RK Naidoo, B Kirby-McCullough, and R Bauer