Browse research from the School of Biomedical Sciences.
Submissions from 2008
Energization-dependent endogenous activation of proton conductance in skeletal muscle mitochondria., Nadeene Parker, Charles Affourtit, Antonio Vidal-Puig, and Martin D. Brand
Massive Autophosphorylation of the Ser/Thr-Rich Domain Controls Protein Kinase Activity of TRPM6 and TRPM7, K Clark, J Middelbeek, NA Morrice, and et al
The regulation of SIRT2 function by cyclin-dependent kinases affects cell motility, R Pandithage, R Lilischkis, K Harting, A Wolf, and et al
Regulation of multiple angiogenic pathways by Dll4 and Notch in human umbilical vein endothelial cells, LS Harrington, RCA Sainson, CK Williams, JM Taylor, and et al
Transforming growth factor-beta enables NFATc1 expression during osteoclastogenesis., SW Fox, KE Evans, and AC Lovibond
Key role of splenic myeloid DCs in the IFN-alphabeta response to adenoviruses in vivo., György Fejer, Lisa Drechsel, Jan Liese, Ulrike Schleicher, Zsolt Ruzsics, Nicola Imelli, Urs F. Greber, Simone Keck, Bernd Hildenbrand, Anne Krug, Christian Bogdan, and Marina A. Freudenberg
Resting CD4+ effector memory T cells are precursors of bystander-activated effectors: a surrogate model of rheumatoid arthritis synovial T-cell function., Fionula M. Brennan, Nicola M.G. Smith, Sally Owen, Ching Li, Parisa Amjadi, Patricia Green, Anna Andersson, Andrew C. Palfreeman, Philippa Hillyer, Andrew Foey, Jonathan T. Beech, and Marc Feldmann
Systems biology meets stress ecology: linking molecular and organismal stress responses in Daphnia magna, L-H Heckmann, RM Sibly, R Connon, HL Hooper, and et al
The two homologous chaperonin 60 proteins of Mycobacterium tuberculosis have distinct effects on monocyte differentiation into osteoclasts, VR Winrow, J Mesher, S Meghji, CJ Morris, M Maguire, S Fox, ARM Coates, P Tormay, DR Blake, and B Henderson
Submissions from 2007
Delta-like 4 Notch Ligand Regulates Tumor Angiogenesis, Improves Tumor Vascular Function, and Promotes Tumor Growth In vivo, J-L Li, RCA Sainson, W Shi, R Leek, and et al
The Potential of New Tumor Endothelium-Specific Markers for the Development of Antivascular Therapy, J-L Li and AL Harris
Interleukin-10 inhibits osteoclastogenesis by reducing NFATc1 expression and preventing its translocation to the nucleus., KE Evans and SW Fox
UniHI: an entry gate to the human protein interactome, Matthias E. Futschik, Gautam Chaurasia, Yasir Iqbal, Christian Hänig, Hanspeter Herzel, and Erich E. Wanker
Submissions from 2006
Up-Regulation of Endothelial Delta-like 4 Expression Correlates with Vessel Maturation in Bladder Cancer, NS Patel, MS Dobbie, M Rochester, G Steers, and et al
Up-regulation of the Notch ligand Delta-like 4 inhibits VEGF-induced endothelial cell function, CK Williams, J-L Li, M Murga, AL Harris, and G Tosato
Lung Nodule Detection in Screening Computed Tomography, I Gori, R Bellotti, P Cerello, SC Cheran, and et al
Submissions from 2005
Endogenous human cytomegalovirus gB is presented efficiently by MHC class II molecules to CD4+ CTL, David C. Johnson, Nagendra R. Hegde, Claire Dunn, David M. Lewinsohn, Michael A. Jarvis, and Jay A. Nelson
Notch signaling from tumor cells: A new mechanism of angiogenesis, J-L Li and AL Harris
Current insights into the role of transforming growth factor-beta in bone resorption, SW Fox and AC Lovibond
Submissions from 2004
Model selection and efficiency testing for normalization of cDNA microarray, Matthias Futschik and Toni Crompton
Submissions from 2003
Functional Interaction between the Bloom's Syndrome Helicase and the RAD51 Paralog, RAD51L3 (RAD51D), JP Braybrooke, J-L Li, L Wu, and et al
Characterisation of a sexual stage-specific gene encoding ORC1 homologue in the human malaria parasite Plasmodium falciparum, J-L Li and LS Cox
Complete analysis of the B‐cell response to a protein antigen, from in vivo germinal centre formation to 3‐D modelling of affinity maturation, CL Adams, MKL Macleod, EJ Milner-White, and et al
A longitudinal study of the effect of subcutaneous estrogen replacement on bone in young women with Turner's syndrome, G Khastgir, JWW Studd, SW Fox, J Jones, J aghband-Zadeh, and JWM Chow
Impact of VIP and cAMP on the regulation of TNF-alpha and IL-10 production: implications for rheumatoid arthritis, AD Foey, S Field, S Ahmed, A Jain, M Feldmann, FM Brennan, and R Williams
Supporting biosciences in the nursing curriculum: development and evaluation of an online resource, KA Gresty and DRE Cotton
TGF-beta-induced SOCS3 expression augments TNF-alpha-induced osteoclast formation, AC Lovibond, SJ Haque, TJ Chambers, and SW Fox
The possible role of TGF-beta-induced suppressors of cytokine signaling expression in osteoclast/macrophage lineage commitment in vitro, SW Fox, SJ Haque, AC Lovibond, and TJ Chambers
Submissions from 2002
Identification of a second proliferating cell nuclear antigen in the human malarial pathogen Plasmodium falciparum, J-L Li, AV Warren, and LS Cox
The Processing of Holliday Junctions by BLM and WRN Helicases Is Regulated by p53, Q Yang, R Zhang, XW Wang, EA Spillare, and et al
TNFα Potently Activates Osteoclasts, through a Direct Action Independent of and Strongly Synergistic with RANKL., K Fuller, C Murphy, S Fox, B Kirstein, and TJ Chambers
Cytokine regulation in RA synovial tissue: role of T cell/macrophage contact-dependent interactions., Fionula Brennan and Andrew Foey
Cytokine-stimulated T cells induce macrophage IL-10 production dependent on phosphatidylinositol 3-kinase and p70S6K: implications for rheumatoid arthritis, A Foey, P Green, B Foxwell, M Feldmann, and F Brennan
Submissions from 2001
Inhibition of the Bloom's and Werner's Syndrome Helicases by G-Quadruplex Interacting Ligands, J-L Li, RJ Harrison, AP Reszka, RM Brosh, and et al
Identification of an MCM4 homologue expressed specifically in the sexual stage of Plasmodium falciparum, J-L Li and LS Cox
Primary structure and sexual stage-specific expression of a LAMMER protein kinase of Plasmodium falciparum, J-L Li, GAT Targett, and DA Baker
Anabolic effect of estrogen replacement on bone in postmenopausal women with osteoporosis: Histomorphometric evidence in a longitudinal study., G Khastgir, J Studd, N Holland, J Alaghband-Zadeh, S Fox, and J Chow
Submissions from 2000
Guanylyl Cyclase Activity Associated with Putative Bifunctional Integral Membrane Proteins in Plasmodium falciparum, DJ Carucci, AA Witney, DK Muhia, DC Warhurst, and et al
The Bloom's syndrome gene product promotes branch migration of Holliday junctions, JK Karow, A Constantinou, J-L Li, SC West, and ID Hickson
Molecular cloning of a gene encoding a 20S proteasome β subunit from Plasmodium falciparum, G-D Li, J-L Li, M Mugthin, and SA Ward
Sexual stage-specific expression of a third calcium-dependent protein kinase from Plasmodium falciparum, J-L Li, DA Baker, and LS Cox
TGF-beta and IFN-gamma direct macrophage activation by TNF-alpha to osteoclastic or cytocidal phenotype., SW Fox, K Fuller, KE Bayley, and TJ Chambers
Submissions from 1999
A Family of PP2 Phosphatases in Plasmodium falciparum and Parasitic Protozoa: Reply, DA Baker and J-L Li
Submissions from 1998
Nitric oxide synthase expression in bone cells., SW Fox and JMW Chow
Submissions from 1996
Pfmrk, A MO15‐Related Protein Kinase from Plasmodium falciparum, J Li, KJH Robson, J Chen, GAT Targett, and DA Baker
Submissions from 1993
Serum-free medium for long-term growth, freezing, cloning and fusion of myelomas and hybridomas, J-L Li, Y-J Li, S Chao, M-H Ouyang, and Y-B Peng
