Mosaic tetracycline resistance genes encoding ribosomal protection proteins
dc.contributor.author | Warburton, PJ | |
dc.contributor.author | Amodeo, N | |
dc.contributor.author | Roberts, AP | |
dc.date.accessioned | 2016-08-18T08:21:35Z | |
dc.date.available | 2016-08-18T08:21:35Z | |
dc.date.issued | 2016-08-03 | |
dc.identifier.issn | 0305-7453 | |
dc.identifier.issn | 1460-2091 | |
dc.identifier.uri | http://hdl.handle.net/10026.1/5329 | |
dc.description.abstract |
First reported in 2003, mosaic tetracycline resistance genes are a subgroup of the genes encoding ribosomal protection proteins (RPPs). They are formed when two or more RPP-encoding genes recombine resulting in a functional chimera. To date, the majority of mosaic genes are derived from sections of three RPP genes, tet(O), tet(W) and tet(32), with others comprising tet(M) and tet(S). In this first review of mosaic genes, we report on their structure, diversity and prevalence, and suggest that these genes may be responsible for an under-reported contribution to tetracycline resistance in bacteria. | |
dc.format.extent | dkw304-dkw304 | |
dc.format.medium | Print-Electronic | |
dc.language | en | |
dc.language.iso | en | |
dc.publisher | Oxford University Press (OUP) | |
dc.subject | Animals | |
dc.subject | Bacteria | |
dc.subject | Bacterial Proteins | |
dc.subject | Genes, Bacterial | |
dc.subject | Humans | |
dc.subject | Recombinant Proteins | |
dc.subject | Tetracycline Resistance | |
dc.title | Mosaic tetracycline resistance genes encoding ribosomal protection proteins | |
dc.type | journal-article | |
dc.type | Review | |
plymouth.author-url | https://www.ncbi.nlm.nih.gov/pubmed/27494928 | |
plymouth.issue | 12 | |
plymouth.volume | 71 | |
plymouth.publication-status | Accepted | |
plymouth.journal | Journal of Antimicrobial Chemotherapy | |
dc.identifier.doi | 10.1093/jac/dkw304 | |
plymouth.organisational-group | /Plymouth | |
plymouth.organisational-group | /Plymouth/Faculty of Health | |
plymouth.organisational-group | /Plymouth/Faculty of Health/School of Biomedical Sciences | |
plymouth.organisational-group | /Plymouth/REF 2021 Researchers by UoA | |
plymouth.organisational-group | /Plymouth/REF 2021 Researchers by UoA/UoA01 Clinical Medicine | |
plymouth.organisational-group | /Plymouth/Users by role | |
plymouth.organisational-group | /Plymouth/Users by role/Academics | |
dc.publisher.place | England | |
dcterms.dateAccepted | 2016-06-29 | |
dc.identifier.eissn | 1460-2091 | |
dc.rights.embargoperiod | No embargo | |
rioxxterms.versionofrecord | 10.1093/jac/dkw304 | |
rioxxterms.licenseref.uri | http://www.rioxx.net/licenses/all-rights-reserved | |
rioxxterms.licenseref.startdate | 2016-08-03 | |
rioxxterms.type | Journal Article/Review | |
plymouth.oa-location | https://academic.oup.com/jac/article-lookup/doi/10.1093/jac/dkw304 |