School of Biomedical Sciences
Recent Submissions
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A simple method for rapid cloning of complete herpesvirus genomes
(Elsevier BVUnited States, 2024-01)Herpesviruses are large DNA viruses and include important human and veterinary pathogens. Their genomes can be cloned as bacterial artificial chromosomes (BACs) and genetically engineered in Escherichia coli using BAC ... -
The effect of breathing hypoxic gas (15% FIO<sub>2</sub>) on physiological and behavioral outcomes during simulated driving in healthy subjects
(WileyUnited States, 2024-03)<jats:title>Abstract</jats:title><jats:p>Hypoxia is mainly caused by cardiopulmonary disease or high‐altitude exposure. We used a driving simulator to investigate whether breathing hypoxic gas influences driving behaviors ... -
Non-allergist healthcare workers views on delivering a penicillin allergy de-labelling inpatient pathway: identifying the barriers and enablers
(Oxford University Press (OUP), 2023-12-28)Background Non-allergist delivered PADL is supported by UK and World Health Organization guidelines but is not yet routine in UK hospitals. Understanding the views of healthcare workers (HCWs) on managing patients with ... -
Mitochondrial involvement in sarcopenia
Sarcopenia lowers the quality‐of‐life for millions of people across the world, as accelerated loss of skeletal muscle mass and function contributes to both age‐ and disease‐related frailty. Physical activity remains the ... -
Amplifying PCR productivity and environmental sustainability through shortened cycling protocols
(Elsevier BVFrance, 2024-01)Since its inception in the 1980s, advancements in PCR technology using improved thermal cyclers, engineered DNA polymerases and commercial master mixes, have led to increased PCR productivity. Despite these advancements, ... -
Runx2 regulates peripheral nerve regeneration to promote Schwann cell migration and re-myelination
(MedknowIndia, 2024-07)Runx2 is a major regulator of osteoblast differentiation and function; however, the role of Runx2 in peripheral nerve repair is unclear. Here, we analyzed Runx2 expression following injury and found that it was specifically ... -
Midterm Clinical Outcomes of Reimplantation Versus Remodeling Valve-Sparing Aortic Root Replacement in Patients With Connective Tissue Disorders: A Meta-Analysis
(Elsevier BVUnited States, 2024-02)This meta-analysis aimed to compare the midterm clinical outcomes of reimplantation versus remodeling techniques for valve-sparing aortic root replacement (VSARR) in patients with connective tissue disorders (CTDs). Studies ... -
Comparison of biomedical science students’ perceptions of online versus paper-based examinations
(Frontiers Media, 2024-01-08)Introduction: Online examinations are becoming increasingly incorporated into higher education. However, Biomedical Science students’ perspectives on exam format preferences remains unexplored. This study aims to investigate ... -
Transcatheter aortic valve implantation versus surgical aortic valve replacement in dialysis-dependent patients: a meta-analysis
(Ovid Technologies (Wolters Kluwer Health)United States, 2023-09)<jats:sec> <jats:title>Objectives</jats:title> <jats:p>This meta-analysis aims to compare the clinical outcomes of transcatheter aortic valve implantation (TAVI) versus aortic valve replacement ... -
Hypertension alters the function and expression profile of the peptide cotransporters PEPT1 and PEPT2 in the rodent renal proximal tubule
(Springer Science and Business Media LLCAustria, 2022-07)Hypertension is a major risk factor for kidney and cardiovascular disease. The treatment of hypertensive individuals by selected ACE inhibitors and certain di-and tripeptides halts the progression of renal deterioration ...