• What’s really down the hospital plughole? 

  Butler, J; Upton, Mathew (Elsevier BVEngland, 2023-04)
• Pandemic Struggles of the Mad Professor 

  King, N::0000-0001-6989-5760 (Oxford University Press (OUP)United States, 2021-03-16)
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  Subunit Vaccine Targeting Phosphate ABC Transporter ATP-Binding Protein, PstB, Provides Cross-Protection against Streptococcus suis Serotype 2, 7, and 9 in Mice 

  Yan, Z; Yao, X; Pan, R; Zhang, J; Ma, X; Dong, N; Wei, J; Liu, K; Qiu, Y; Sealey, K; Nichols, H; Jarvis, Michael A; Upton, Mathew; Li, X; Ma, Z; Liu, J; Li, B (MDPI AG, 2023-01-09)

  Streptococcus suis is a significant pathogen in pigs and a newly emerging zoonotic agent in humans. The presence of multiple serotypes and strains with diversified sequence types in pig herds highlights the need for the ...
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  ErbB- and MUC1-targetted CAR-T cell immunotherapy of oral squamous cell carcinoma 

  Summers, SE; Salih, V; Foey, Andrew (Frontiers Media SA, 2023-03-13)

  Chimeric antigen receptor T (CAR-T) cell therapy has shown great success in treating B cell malignancies however, there are many challenges which limit their therapeutic efficacy in solid tumours. Immunotherapy of head ...
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  Genistein and coumestrol reduce MCF-7 breast cancer cell viability and inhibit markers of preferential metastasis, bone matrix attachment and tumor-induced osteoclastogenesis 

  Al-Thamiree Mezban, S; Fox, Simon (ElsevierUnited States, 2023-05-15)

  The propensity of breast cancer to preferentially metastasize to the skeleton is well known. Once established in bone metastatic breast cancers have a poor prognosis due to their ability to promote extensive bone loss ...
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  The effects of acute hypoxia on cognitive and cardiovascular parameters in healthy subjects 

  Ravi, R; Subhan, Mirza (Academia.edu, 2023-03-16)

  Background: Hypoxia can affect the health and safety of patients and persons in various occupations. There is uncertainty surrounding the effect acute hypoxia may have on cognition and the cardiovascular system. Aims: The ...
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  Whole genomes of deep-sea sponge-associated bacteria exhibit high novel natural product potential 

  Hesketh-Best, PJ; January, GG; Koch, MJ; Warburton, Philip; Howell, Kerry; Upton, Mathew (Oxford University Press (OUP), 2023-02-22)

  Abstract Global antimicrobial resistance is a health crisis that can change the face of modern medicine. Exploring diverse natural habitats for bacterially-derived novel antimicrobial compounds has historically been a ...
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  Optimization of sniff nasal inspiratory pressure (SNIP) measurement methodology in healthy subjects. 

  Subhan, Mirza (BioMed CentralEngland, 2023-02-15)

  Background Maximal inspiratory pressure (MIP) is currently the most commonly used measure for respiratory muscle strength (RMS) estimation, however, requires significant effort. Falsely low values are therefore common, ...
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  Characterising a human endogenous retrovirus(HERV)-derived tumour-associated antigen: enriched RNA-Seq analysis of HERV-K(HML-2) in mantle cell lymphoma cell lines 

  Tatkiewicz, W; Dickie, J; Bedford, F; Jones, A; Atkin, M; Kiernan, Michele; Maze, EA; Agit, B; Farnham, G; Kanapin, A; Belshaw, Robert (Springer Science and Business Media LLCEngland, 2020-12)

  Background The cell-surface attachment protein (Env) of the HERV-K(HML-2) lineage of endogenous retroviruses is a potentially attractive tumour-associated antigen for anti-cancer immunotherapy. The human genome contains ...
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  Nitric oxide synthase expression in bone cells. 

  Fox, Simon; Chow, JMW (Elsevier BVUnited States, 1998)

  We have localized the expression of the three main nitric oxide synthases (eNOS, bNOS, and iNOS) in bone cells of rats and humans using immunohistochemistry. The predominant isoform expressed in normal adult bone was the ...

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