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  Endotoxin as a Marker for Water Quality 

  Sattar, Anas; Good, CR; Saletes, M; Brandão, João; Jackson, SK (MDPI AGSwitzerland, 2022-12)

  Background: Water quality testing is vital to protect human health. Current testing relies mainly on culture-based detection of faecal indicator organisms such as Escherichia coli (E.coli). However, bacterial cultures are ...
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  Toll-like receptor 4 and macrophage scavenger receptor 1 crosstalk regulates phagocytosis of a fungal pathogen 

  Onyishi, Chinaemerem Uju; Desanti, GE; Wilkinson, Alex; Lara-Reyna, Samuel; Frickel, Eva; Fejer, Gyorgy; Christophe, OD; Bryant, Clare Elizabeth; Mukhopadhyay, Subhankar; gordon, siamon; May, RC::0000-0001-5364-1838 (Springer Science and Business Media LLCEngland, 2023-08-14)

  The opportunistic fungal pathogen Cryptococcus neoformans causes lethal infections in immunocompromised patients. Macrophages are central to the host response to cryptococci; however, it is unclear how C. neoformans is ...
• An attenuated herpesvirus vectored vaccine candidate induces T-cell responses against highly conserved porcine reproductive and respiratory syndrome virus M and NSP5 proteins that are unable to control infection 

  de Brito, RCF; Holtham, K; Roser, J; Saunders, JE; Wezel, Y; Henderson, S; Mauch, T; Sanz-Bernardo, B; Frossard, J-P; Bernard, M; Lean, FZX; Nunez, A; Gubbins, S; Suárez, NM; Davison, AJ; Francis, MJ; Huether, M; Benchaoui, H; Salt, J; Fowler, VL; Jarvis, Michael A; Graham, SP (Frontiers Media SASwitzerland, 2023-08-03)

  <jats:p>Porcine reproductive and respiratory syndrome virus (PRRSV) remains a leading cause of economic loss in pig farming worldwide. Existing commercial vaccines, all based on modified live or inactivated PRRSV, fail ...
• Rationally designed chemokine-based toxin targeting the viral G protein-coupled receptor US28 potently inhibits cytomegalovirus infection in vivo 

  Spiess, K; Jeppesen, MG; Malmgaard-Clausen, M; Krzywkowski, K; Dulal, K; Cheng, T; Hjortø, GM; Larsen, O; Burg, JS; Jarvis, Michael A; Garcia, KC; Zhu, H; Kledal, TN; Rosenkilde, MM (Proceedings of the National Academy of SciencesUnited States, 2015-07-07)

  <jats:title>Significance</jats:title> <jats:p>All drugs currently used for the clinical treatment of human cytomegalovirus (HCMV) infection are associated with considerable adverse side effects and with the ...
• Isolation and genome sequencing of cytomegaloviruses from Natal multimammate mice (Mastomys natalensis) 

  Hansen, F; Vučak, M; Nichols, J; Hughes, J; Bane, S; Camiolo, S; da Silva Filipe, A; Ostermann, E; Staliunaite, L; Chan, B; Mauch, T; Sogoba, N; Streblow, DN; Voigt, S; Oestereich, L; Ehlers, B; Redwood, AJ; Feldmann, H; Brune, W; Rosenke, K; Jarvis, Michael A; Davison, AJ (Microbiology SocietyEngland, 2023-08-29)

  <jats:p>Distinct cytomegaloviruses (CMVs) are widely distributed across their mammalian hosts in a highly host species-restricted pattern. To date, evidence demonstrating this has been limited largely to PCR-based approaches ...
• Discovery of a polyomavirus in European badgers (Meles meles) and the evolution of host range in the family Polyomaviridae. 

  Hill, SC; Murphy, Aisling; Cotten, M; Palser, AL; Benson, P; Lesellier, S; Gormley, E; Richomme, C; Grierson, S; Bhuachalla, DN; Chambers, M; Kellam, P; Boschiroli, M-L; Ehlers, B; Jarvis, Michael A; Pybus, OG (England, 2015-06)

  Polyomaviruses infect a diverse range of mammalian and avian hosts, and are associated with a variety of symptoms. However, it is unknown whether the viruses are found in all mammalian families and the evolutionary history ...
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  The Potential of Probiotics as Ingestible Adjuvants and Immune Modulators for Antiviral Immunity and Management of SARS-CoV-2 Infection and COVID-19 

  Tomkinson, S; Triscott, C; Schenk, E; Foey, Andrew (MDPI AGSwitzerland, 2023-07)

  <jats:p>Probiotic bacteria are able to modulate general antiviral responsiveness, including barrier functionality and innate and adaptive immune responses. The COVID-19 pandemic, resulting from SARS-CoV-2 infection, has ...
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  Air quality and mental health: evidence, challenges and future directions 

  Bhui, Kamaldeep; Newbury, JB; Latham, Rachel; Ucci, M; Nasir, ZA; Turner, B; O'Leary, C; Fisher, Helen; Marczylo, E; Douglas, P; Stansfeld, S::0000-0001-8716-3897; Jackson, SK; Tyrrel, S; Rzhetsky, A; Kinnersley, R; Kumar, P; Duchaine, C; Coulon, Frederic (Royal College of PsychiatristsEngland, 2023-07)

  Background Poor air quality is associated with poor health. Little attention is given to the complex array of environmental exposures and air pollutants that affect mental health during the life course. Aims We gather ...
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  A metabologenomics approach to unlock the metabolome of the novel Antarctic deep-sea isolate <i>Lacinutrix shetlandiensis</i> sp. nov. WUR7 

  Vitale, Giovanni Andrea; January, Grant; Oppong-Danquah, Ernest; Della Sala, Gerardo; Palma Esposito, Fortunato; Tasdemir, Deniz; de Pascale, Donatella (Oxford University Press (OUP)England, 2023-07-03)

  <jats:title>Abstract</jats:title> <jats:p>The South Shetland Trough, Antarctica, is an underexplored region for microbiological and biotechnological exploitation. Herein, we describe the isolation and ...
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  RHD molecular analysis—from discovery to next generation sequencing 

  Madgett, TE::0000-0002-3463-1922; Tounsi, WA; Halawani, AJ; Avent, ND (2023-07-27)

  This review traces the evolution of RHD genotyping from the very early days of the discovery of Rh polypeptides in 1982, and the pioneering work of the late 1980s and early 1990s that made the whole approach of RH genotyping ...

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