Facilitated physical activity as a treatment for depressed adults: randomised controlled trial
dc.contributor.author | Chalder, M | |
dc.contributor.author | Wiles, NJ | |
dc.contributor.author | Campbell, J | |
dc.contributor.author | Hollinghurst, SP | |
dc.contributor.author | Haase, AM | |
dc.contributor.author | Taylor, Adrian | |
dc.contributor.author | Fox, KR | |
dc.contributor.author | Costelloe, C | |
dc.contributor.author | Searle, A | |
dc.contributor.author | Baxter, H | |
dc.contributor.author | Winder, Rachel | |
dc.contributor.author | Wright, C | |
dc.contributor.author | Turner, KM | |
dc.contributor.author | Calnan, M | |
dc.contributor.author | Lawlor, DA | |
dc.contributor.author | Peters, TJ | |
dc.contributor.author | Sharp, DJ | |
dc.contributor.author | Montgomery, AA | |
dc.contributor.author | Lewis, G | |
dc.date.accessioned | 2016-02-11T09:43:12Z | |
dc.date.available | 2016-02-11T09:43:12Z | |
dc.date.issued | 2012-06-06 | |
dc.identifier.issn | 0959-535X | |
dc.identifier.issn | 1756-1833 | |
dc.identifier.other | ARTN e2758 | |
dc.identifier.uri | http://hdl.handle.net/10026.1/4308 | |
dc.description.abstract |
OBJECTIVE: To investigate the effectiveness of facilitated physical activity as an adjunctive treatment for adults with depression presenting in primary care. DESIGN: Pragmatic, multicentre, two arm parallel randomised controlled trial. SETTING: General practices in Bristol and Exeter. PARTICIPANTS: 361 adults aged 18-69 who had recently consulted their general practitioner with symptoms of depression. All those randomised had a diagnosis of an episode of depression as assessed by the clinical interview schedule-revised and a Beck depression inventory score of 14 or more. INTERVENTIONS: In addition to usual care, intervention participants were offered up to three face to face sessions and 10 telephone calls with a trained physical activity facilitator over eight months. The intervention was based on theory and aimed to provide individually tailored support and encouragement to engage in physical activity. MAIN OUTCOME MEASURES: The primary outcome was self reported symptoms of depression, assessed with the Beck depression inventory at four months post-randomisation. Secondary outcomes included use of antidepressants and physical activity at the four, eight, and 12 month follow-up points, and symptoms of depression at eight and 12 month follow-up. RESULTS: There was no evidence that participants offered the physical activity intervention reported improvement in mood by the four month follow-up point compared with those in the usual care group; adjusted between group difference in mean Beck depression inventory score -0.54 (95% confidence interval -3.06 to 1.99; P=0.68). Similarly, there was no evidence that the intervention group reported a change in mood by the eight and 12 month follow-up points. Nor was there evidence that the intervention reduced antidepressant use compared with usual care (adjusted odds ratio 0.63, 95% confidence interval 0.19 to 2.06; P=0.44) over the duration of the trial. However, participants allocated to the intervention group reported more physical activity during the follow-up period than those allocated to the usual care group (adjusted odds ratio 2.27, 95% confidence interval 1.32 to 3.89; P=0.003). CONCLUSIONS: The addition of a facilitated physical activity intervention to usual care did not improve depression outcome or reduce use of antidepressants compared with usual care alone. TRIAL REGISTRATION: Current Controlled Trials ISRCTN16900744. | |
dc.format.extent | e2758-e2758 | |
dc.format.medium | Electronic | |
dc.language | en | |
dc.language.iso | eng | |
dc.publisher | BMJ | |
dc.subject | Adolescent | |
dc.subject | Adult | |
dc.subject | Aged | |
dc.subject | Antidepressive Agents | |
dc.subject | Depression | |
dc.subject | England | |
dc.subject | Exercise Therapy | |
dc.subject | Female | |
dc.subject | Humans | |
dc.subject | Male | |
dc.subject | Middle Aged | |
dc.subject | Primary Health Care | |
dc.subject | Psychiatric Status Rating Scales | |
dc.subject | Regression Analysis | |
dc.subject | Treatment Outcome | |
dc.title | Facilitated physical activity as a treatment for depressed adults: randomised controlled trial | |
dc.type | journal-article | |
dc.type | Journal Article | |
dc.type | Multicenter Study | |
dc.type | Randomized Controlled Trial | |
dc.type | Research Support, Non-U.S. Gov't | |
plymouth.author-url | https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000305184700002&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=11bb513d99f797142bcfeffcc58ea008 | |
plymouth.issue | jun06 1 | |
plymouth.volume | 344 | |
plymouth.publication-status | Published | |
plymouth.journal | BMJ | |
dc.identifier.doi | 10.1136/bmj.e2758 | |
plymouth.organisational-group | /Plymouth | |
plymouth.organisational-group | /Plymouth/Faculty of Health | |
plymouth.organisational-group | /Plymouth/Faculty of Health/Peninsula Medical School | |
plymouth.organisational-group | /Plymouth/REF 2021 Researchers by UoA | |
plymouth.organisational-group | /Plymouth/REF 2021 Researchers by UoA/UoA03 Allied Health Professions, Dentistry, Nursing and Pharmacy | |
plymouth.organisational-group | /Plymouth/Research Groups | |
plymouth.organisational-group | /Plymouth/Research Groups/FoH - Community and Primary Care | |
plymouth.organisational-group | /Plymouth/Research Groups/Institute of Health and Community | |
plymouth.organisational-group | /Plymouth/Research Groups/Institute of Translational and Stratified Medicine (ITSMED) | |
plymouth.organisational-group | /Plymouth/Research Groups/Institute of Translational and Stratified Medicine (ITSMED)/CCT&PS | |
plymouth.organisational-group | /Plymouth/Research Groups/Plymouth Institute of Health and Care Research (PIHR) | |
plymouth.organisational-group | /Plymouth/Users by role | |
plymouth.organisational-group | /Plymouth/Users by role/Academics | |
plymouth.organisational-group | /Plymouth/Users by role/Researchers in ResearchFish submission | |
dc.publisher.place | England | |
dc.identifier.eissn | 1756-1833 | |
dc.rights.embargoperiod | Not known | |
rioxxterms.versionofrecord | 10.1136/bmj.e2758 | |
rioxxterms.licenseref.uri | http://www.rioxx.net/licenses/all-rights-reserved | |
rioxxterms.type | Journal Article/Review |