Browsing Peninsula Medical School by Issue Date
Now showing items 1-20 of 261
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An improved method for the large-scale processing of woad (Isatis tinctoria) for possible commercial production of woad indigo
(1998-01-01)The increasing use of alternative crops has meant the introduction of new technologies to process their products. In this work, an alternative method is presented for the extraction of natural indigo from woad (Isatis ... -
Stability of intravesical epirubicin infusion: a sequential temperature study.
(England, 2003-10)OBJECTIVE: To investigate the stability of epirubicin bladder instillation, prepared from two different epirubicin formulations, under refrigerated storage, transportation and clinical use conditions. METHOD: A sequential ... -
A new HPLC-ELSD method to quantify indican in Polygonum tinctorium L. and to evaluate beta-glucosidase hydrolysis of indican for indigo production.
(United States, 2003-11)A method to quantify the indigo precursor indican (indoxyl-beta-D-glucoside) in Polygonum tinctorium L. has been developed. Plant material was extracted in deionized water, and indican was identified and quantified using ... -
Quantitative analysis of indigo and indigo precursors in leaves of Isatis spp. and Polygonum tinctorium.
(United States, 2004-07)Analysis of extracts from two woad species (Isatis tinctoria and Isatis indigotica) and Polygonum tinctorium revealed that only one indigo precursor (indican) was present in Polygonum, but two precursors were found in ... -
Sowing date, transplanting, plant density and nitrogen fertilization affect indigo production from Isatis species in a Mediterranean region of Spain
(2006-01-01)The increasing interest in natural products from a renewable source has encouraged growers to reintroduce indigo-producing crops into the European agriculture. We studied agronomic conditions (sowing date, plant density, ... -
A genome-wide association study identifies protein quantitative trait loci (pQTLs).
(United States, 2008-05-09)There is considerable evidence that human genetic variation influences gene expression. Genome-wide studies have revealed that mRNA levels are associated with genetic variation in or close to the gene coding for those ... -
Assessing fitness for surgery: a comparison of questionnaire, incremental shuttle walk, and cardiopulmonary exercise testing in general surgical patients.
(England, 2008-12)BACKGROUND: Morbidity and mortality are higher in patients with poor preoperative cardiorespiratory reserve. This study aimed to ascertain fitness and therefore risk in elective patients, comparing three measures: Duke ... -
Off-label use of medicines is bad medicine flying the flag of clinical freedom.
(Netherlands, 2009-07) -
Droperidol: past, present and future.
(England, 2009-11) -
Tracheal intubation without neuromuscular blocking agents: is there any point?
(England, 2010-05) -
The anaesthetist and the environment.
(England, 2010-05) -
The transition from medical student to junior doctor: today's experiences of Tomorrow's Doctors.
(England, 2010-05)CONTEXT Medical education in the UK has recently undergone radical reform. Tomorrow's Doctors has prescribed undergraduate curriculum change and the Foundation Programme has overhauled postgraduate education. OBJECTIVES ... -
First administration to man of Org 25435, an intravenous anaesthetic: A Phase 1 Clinical Trial.
(England, 2010-06-29)BACKGROUND: Org 25435 is a new water-soluble alpha-amino acid ester intravenous anaesthetic which proved satisfactory in animal studies. This study aimed to assess the safety, tolerability and efficacy of Org 25435 and ... -
New drugs and technologies, intravenous anaesthesia is on the move (again).
(England, 2010-09)Although well established in clinical practice, both propofol and midazolam have limitations. New hypnotics with different and potentially superior pharmacokinetics and pharmacodynamics are under development. These include ... -
Physical activity as a treatment for depression: the TREAD randomised trial protocol.
(England, 2010-11-12)BACKGROUND: Depression is one of the most common reasons for consulting a General Practitioner (GP) within the UK. Whilst antidepressants have been shown to be clinically effective, many patients and healthcare professionals ... -
Integrating the promotion of physical activity within a smoking cessation programme: findings from collaborative action research in UK Stop Smoking Services.
(England, 2010-11-25)BACKGROUND: Within the framework of collaborative action research, the aim was to explore the feasibility of developing and embedding physical activity promotion as a smoking cessation aid within UK 6/7-week National ... -
Propofol and children--what we know and what we do not know.
(France, 2011-03)The pharmacokinetics of propofol are relatively well described in the pediatric population. Recent work has confirmed the validity of allometric scaling for predicting propofol disposition across different species and for ...
