Stability of intravesical epirubicin infusion: a sequential temperature study
dc.contributor.author | Sewell, GJ | |
dc.contributor.author | Rigby-Jones, AE | |
dc.contributor.author | Priston, MJ | |
dc.date.accessioned | 2015-10-27T16:47:31Z | |
dc.date.available | 2015-10-27T16:47:31Z | |
dc.date.issued | 2003-10 | |
dc.identifier.issn | 0269-4727 | |
dc.identifier.issn | 1365-2710 | |
dc.identifier.uri | http://hdl.handle.net/10026.1/3728 | |
dc.description.abstract |
OBJECTIVE: To investigate the stability of epirubicin bladder instillation, prepared from two different epirubicin formulations, under refrigerated storage, transportation and clinical use conditions. METHOD: A sequential study design was used. Epirubicin instillation (1 mg/mL) in polypropylene syringes was sequential incubated for periods of 84 days at 8 degrees C followed by 2 h at 25 degrees C and 1 h at 37 degrees C, the latter two temperatures replicating transport and intravesical conditions, respectively. RESULTS: The instillation was both chemically and physically stable under those incubation conditions. The formulation of epirubicin used to prepare the instillation infusions did not affect stability. | |
dc.format.extent | 349-353 | |
dc.format.medium | ||
dc.language | en | |
dc.language.iso | eng | |
dc.publisher | Hindawi Limited | |
dc.subject | epirubicin | |
dc.subject | intravesical infusion | |
dc.subject | stability | |
dc.title | Stability of intravesical epirubicin infusion: a sequential temperature study | |
dc.type | journal-article | |
dc.type | Journal Article | |
plymouth.author-url | https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000186417900002&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=11bb513d99f797142bcfeffcc58ea008 | |
plymouth.issue | 5 | |
plymouth.volume | 28 | |
plymouth.publication-status | Published | |
plymouth.journal | Journal of Clinical Pharmacy and Therapeutics | |
dc.identifier.doi | 10.1046/j.0269-4727.2003.00501.x | |
plymouth.organisational-group | /Plymouth | |
plymouth.organisational-group | /Plymouth/Faculty of Health | |
plymouth.organisational-group | /Plymouth/Faculty of Health/Peninsula Medical School | |
plymouth.organisational-group | /Plymouth/Faculty of Health/School of Health Professions | |
plymouth.organisational-group | /Plymouth/REF 2021 Researchers by UoA | |
plymouth.organisational-group | /Plymouth/REF 2021 Researchers by UoA/UoA03 Allied Health Professions, Dentistry, Nursing and Pharmacy | |
plymouth.organisational-group | /Plymouth/REF 2021 Researchers by UoA/UoA03 Allied Health Professions, Dentistry, Nursing and Pharmacy/UoA03 Allied Health Professions, Dentistry, Nursing and Pharmacy MANUAL | |
plymouth.organisational-group | /Plymouth/Research Groups | |
plymouth.organisational-group | /Plymouth/Research Groups/Institute of Health and Community | |
plymouth.organisational-group | /Plymouth/Research Groups/Plymouth Institute of Health and Care Research (PIHR) | |
plymouth.organisational-group | /Plymouth/Users by role | |
plymouth.organisational-group | /Plymouth/Users by role/Academics | |
dc.publisher.place | England | |
dc.identifier.eissn | 1365-2710 | |
dc.rights.embargoperiod | Not known | |
rioxxterms.versionofrecord | 10.1046/j.0269-4727.2003.00501.x | |
rioxxterms.licenseref.uri | http://www.rioxx.net/licenses/all-rights-reserved | |
rioxxterms.type | Journal Article/Review |