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dc.contributor.authorPatel, J
dc.contributor.authorBoyer, N
dc.contributor.authorMensah, K
dc.contributor.authorHaider, S
dc.contributor.authorGibson, O
dc.contributor.authorMartin, D
dc.contributor.authorWalter, E
dc.date.accessioned2023-03-01T14:30:45Z
dc.date.available2023-03-01T14:30:45Z
dc.date.issued2023-05
dc.identifier.issn1751-1437
dc.identifier.issn2057-360X
dc.identifier.urihttp://hdl.handle.net/10026.1/20524
dc.description.abstract

<jats:p>Heatstroke represents the most severe end of the heat illness spectrum, and is increasingly seen in those undergoing exercise or exertion (‘exertional heatstroke’) and those exposed to high ambient temperatures, for example in heatwaves (‘classical heatstroke’). Both forms may be associated with significant thermal injury, leading to organ dysfunction and the need for admission to an intensive care unit. The process may be exacerbated by translocation of bacteria or endotoxin through an intestinal wall rendered more permeable by the hyperthermia. This narrative review highlights the importance of early diagnosis, rapid cooling and effective management of complications. It discusses the incidence, clinical features and treatment of heatstroke, and discusses the possible role of intestinal permeability and advances in follow-up and recovery of this condition. Optimum treatment involves an integrated input from prehospital, emergency department and critical care teams, along with follow-up by rehabilitation teams and, if appropriate, sports or clinical physiologists.</jats:p>

dc.format.extent206-214
dc.format.mediumPrint-Electronic
dc.languageen
dc.language.isoen
dc.publisherSAGE Publications
dc.subjectHeatstroke
dc.subjecthyperthermia
dc.subjectexertional heat illness
dc.subjectmultiple organ failure
dc.subjecttherapy
dc.titleCritical illness aspects of heatstroke: A hot topic
dc.typejournal-article
dc.typeReview
dc.typeEarly Access
plymouth.author-urlhttps://www.ncbi.nlm.nih.gov/pubmed/37260431
plymouth.issue2
plymouth.volume24
plymouth.publication-statusPublished
plymouth.journalJournal of the Intensive Care Society
dc.identifier.doi10.1177/17511437221148922
plymouth.organisational-group/Plymouth
plymouth.organisational-group/Plymouth/Faculty of Health
plymouth.organisational-group/Plymouth/Faculty of Health/Peninsula Medical School
plymouth.organisational-group/Plymouth/REF 2021 Researchers by UoA
plymouth.organisational-group/Plymouth/REF 2021 Researchers by UoA/UoA01 Clinical Medicine
plymouth.organisational-group/Plymouth/Users by role
plymouth.organisational-group/Plymouth/Users by role/Academics
dc.publisher.placeEngland
dc.identifier.eissn2057-360X
dc.rights.embargoperiodNot known
rioxxterms.versionofrecord10.1177/17511437221148922
rioxxterms.licenseref.urihttp://www.rioxx.net/licenses/all-rights-reserved
rioxxterms.typeJournal Article/Review


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