Oral health and pathology: a macrophage account
dc.contributor.author | Merry, R | |
dc.contributor.author | Belfield, L | |
dc.contributor.author | McArdle, P | |
dc.contributor.author | McLennan, A | |
dc.contributor.author | Crean, S | |
dc.contributor.author | Foey, A | |
dc.date.accessioned | 2018-10-24T10:44:55Z | |
dc.date.available | 2018-10-24T10:44:55Z | |
dc.date.issued | 2012-01 | |
dc.identifier.issn | 0266-4356 | |
dc.identifier.issn | 1532-1940 | |
dc.identifier.uri | http://hdl.handle.net/10026.1/12619 | |
dc.description.abstract |
Macrophages are present in healthy oral mucosa and their numbers increase dramatically during disease. They can exhibit a diverse range of phenotypes characterised as a functional spectrum from pro-inflammatory to anti-inflammatory (regulatory) subsets. This review illustrates the role of these subsets in the oral inflammatory disease lichen planus, and the immunosuppressive disease oral squamous cell carcinoma (SCC). We conclude that the role of macrophages in driving progression in oral disease identifies them as potential therapeutic targets for a range of oral pathologies. | |
dc.format.extent | 2-7 | |
dc.format.medium | Print-Electronic | |
dc.language | en | |
dc.language.iso | eng | |
dc.publisher | Elsevier BV | |
dc.subject | Oral pathology | |
dc.subject | Immunology | |
dc.subject | Macrophages | |
dc.title | Oral health and pathology: a macrophage account | |
dc.type | journal-article | |
dc.type | Review | |
plymouth.author-url | https://www.ncbi.nlm.nih.gov/pubmed/21310515 | |
plymouth.issue | 1 | |
plymouth.volume | 50 | |
plymouth.publication-status | Published | |
plymouth.journal | British Journal of Oral and Maxillofacial Surgery | |
dc.identifier.doi | 10.1016/j.bjoms.2010.10.020 | |
plymouth.organisational-group | /Plymouth | |
plymouth.organisational-group | /Plymouth/Faculty of Health | |
plymouth.organisational-group | /Plymouth/Faculty of Health/Peninsula Dental School | |
plymouth.organisational-group | /Plymouth/Faculty of Health/School of Biomedical Sciences | |
plymouth.organisational-group | /Plymouth/REF 2021 Researchers by UoA | |
plymouth.organisational-group | /Plymouth/REF 2021 Researchers by UoA/UoA01 Clinical Medicine | |
plymouth.organisational-group | /Plymouth/REF 2021 Researchers by UoA/UoA01 Clinical Medicine/UoA01 Clinical Medicine | |
plymouth.organisational-group | /Plymouth/Research Groups | |
plymouth.organisational-group | /Plymouth/Research Groups/Institute of Translational and Stratified Medicine (ITSMED) | |
plymouth.organisational-group | /Plymouth/Research Groups/Institute of Translational and Stratified Medicine (ITSMED)/CBR | |
plymouth.organisational-group | /Plymouth/Users by role | |
plymouth.organisational-group | /Plymouth/Users by role/Academics | |
dc.publisher.place | Scotland | |
dcterms.dateAccepted | 2010-10-01 | |
dc.identifier.eissn | 1532-1940 | |
dc.rights.embargoperiod | Not known | |
rioxxterms.versionofrecord | 10.1016/j.bjoms.2010.10.020 | |
rioxxterms.licenseref.uri | http://www.rioxx.net/licenses/all-rights-reserved | |
rioxxterms.licenseref.startdate | 2012-01 | |
rioxxterms.type | Journal Article/Review |