ORCID
- Lovleen Tina Joshi: 0000-0002-5965-4055
Abstract
Aim: To investigate the outbreak of Burkholderia cepacia complex (BCC), mortality, antimicrobial resistance and associated risk factors in the neonatal intensive care unit. Method: Eighteen blood culture samples from neonates and twenty swab samples from different neonatal intensive care unit surfaces were collected. The VITEK 2 was used to confirm the isolates and generate the antibiogram. PCR was used to identify blaNDM. Results: Eighteen samples tested positive for BCC, and 10/18 (55.5%) of the neonates died. 13/18 (72%) of the neonates had late-onset neonatal sepsis, and 10/18 (55%) had low birth weight. Resistance to minocycline and chloramphenicol was 100%, 72.2% to meropenem; 72.2% NDM gene was found in neonates and was 20% from the environment. Conclusion: Outbreak of NDM-producing BCC resulting in high neonatal mortality in NICU.
Publication Date
2023-10-18
Publication Title
Future Microbiology
ISSN
1746-0913
Embargo Period
2024-10-17
Recommended Citation
Qamar, M., Batool, A., Yakoob, A., Anwar, Z., Joshi, L., Lone, D., Zikriya, M., & Ahmed, Q. (2023) 'Outbreak investigation of NDM-producing Burkholderia cepacia causing neonatal sepsis in Pakistan', Future Microbiology, . Available at: 10.2217/fmb-2023-0063
