Abstract
Induction of endotoxin tolerance leads to a reduced inflammatory response after repeated challenge by LPS and is important for resolution of inflammation and prevention of tissue damage. Enterobacterial LPS is recognized by the TLR4 signaling complex, whe
DOI
10.1074/jbc.M111.252791
Publication Date
2011-08-26
Publication Title
J Biol Chem
Volume
286
Issue
34
Organisational Unit
Peninsula Dental School
Keywords
Animals, Cell Line, Cytokines, Drug Resistance, Fibroblasts, Humans, Interferon Regulatory Factor-3, Interferon-beta, Lipopolysaccharides, Macrophages, Mice, Knockout, NF-kappa B, Signal Transduction, Toll-Like Receptor 2
First Page
29492
Last Page
29500
Recommended Citation
Zaric, S., Coulter, W., Shelburne, C., Fulton, C., Zaric, M., Scott, A., Lappin, M., Fitzgerald, D., Irwin, C., & Taggart, C. (2011) 'Altered Toll-like receptor 2-mediated endotoxin tolerance is related to diminished interferon beta production.', J Biol Chem, 286(34), pp. 29492-29500. Available at: https://doi.org/10.1074/jbc.M111.252791
