Abstract

Induction of endotoxin tolerance leads to a reduced inflammatory response after repeated challenge by LPS and is important for resolution of inflammation and prevention of tissue damage. Enterobacterial LPS is recognized by the TLR4 signaling complex, whe

DOI

10.1074/jbc.M111.252791

Publication Date

2011-08-26

Publication Title

J Biol Chem

Volume

286

Issue

34

First Page

29492

Last Page

29500

Organisational Unit

Peninsula Dental School

Keywords

Animals, Cell Line, Cytokines, Drug Resistance, Fibroblasts, Humans, Interferon Regulatory Factor-3, Interferon-beta, Lipopolysaccharides, Macrophages, Mice, Knockout, NF-kappa B, Signal Transduction, Toll-Like Receptor 2

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