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dc.contributor.authorShibl, Men
dc.contributor.authorAli, Ken
dc.contributor.authorBurns, Len
dc.date.accessioned2021-06-14T14:17:22Z
dc.date.issued2021-07-08en
dc.identifier.issn0007-0610en
dc.identifier.urihttp://hdl.handle.net/10026.1/17251
dc.description.abstract

Aim: To determine if a single pre-operative dose of oral corticosteroids would be effective in reducing pain, trismus and oedema following lower third molar surgical extraction. Secondary outcomes of interest were post-operative complications such as infections. Methods: Searching was conducted using Embase, MEDLINE, DOSS, CINAHL and CENTRAL for randomised controlled trials. Four studies which compared pre-operative oral corticosteroids to placebo prior to lower third molar surgical extractions were eligible for inclusion. Results: All studies were judged to be at unclear risk of bias. All studies tested the efficacy of 8mg dexamethasone 60-90 minutes prior to surgical extractions. Whilst three studies showed improvement in pain visual analogue scale (VAS) scores in the dexamethasone groups, two were not statistically significant. One study found no improvement in pain scores on VAS. One study found no difference in either trismus or oedema. One study reported one occurrence of post-operative alveolar infection in the dexamethasone group and one occurrence of alveolar osteitis in the placebo group. Conclusion: While there seems to be an improvement in pain scores on VAS, these results are not clinically significant. Post-operative analgesia plays a more important role clinically.

en
dc.language.isoenen
dc.publisherSpringer Nature [academic journals on nature.com]en
dc.subjectcorticosteroidsen
dc.subjectoedemaen
dc.subjectoral surgeryen
dc.subjectpainen
dc.subjectThird molaren
dc.subjecttrismusen
dc.titleEffectiveness of pre-operative oral corticosteroids in reducing pain, trismus and oedema following lower third molar extractions: a systematic reviewen
dc.typeJournal Article
plymouth.journalBritish Dental Journal (BDJ)en
dc.identifier.doi10.1038/s41415-021-3165-yen
plymouth.organisational-group/Plymouth
plymouth.organisational-group/Plymouth/Faculty of Health
plymouth.organisational-group/Plymouth/Faculty of Health/Peninsula Dental School
plymouth.organisational-group/Plymouth/Research Groups
plymouth.organisational-group/Plymouth/Research Groups/Community and Primary Care
plymouth.organisational-group/Plymouth/Research Groups/Institute of Health and Community
plymouth.organisational-group/Plymouth/Users by role
plymouth.organisational-group/Plymouth/Users by role/Academics
dcterms.dateAccepted2020-10-16en
dc.rights.embargodate2022-01-08en
dc.rights.embargoperiodNot knownen
rioxxterms.versionofrecord10.1038/s41415-021-3165-yen
rioxxterms.licenseref.urihttp://www.rioxx.net/licenses/all-rights-reserveden
rioxxterms.licenseref.startdate2021-07-08en
rioxxterms.typeJournal Article/Reviewen


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