Spheroid Size Does not Impact Metabolism of the beta-blocker Propranolol in 3D Intestinal Fish Model

Authors

Awadhesh N. Jha, School of Biological and Marine Sciences
Laura M. Langan
Stewart F. Owen, AstraZeneca
Maciej Trznadel, University of Exeter
Nicholas J.F. Dodd
Simon K. Jackson, School of Biomedical Sciences
Wendy M. Purcell, Harvard University

ORCID

• Awadhesh N. Jha: 0000-0001-9660-4308
• Simon K. Jackson: 0000-0002-5475-7637

DOI

10.3389/fphar.2018.00947

Publication Date

2018-08-22

Publication Title

Frontiers in Pharmacology

Volume

9

ISSN

1663-9812

Embargo Period

2019-11-27

Keywords

spheroids, EPR-oximetry, micro-environment, metabolism, intestine, beta-blocker, propranolol

Recommended Citation

Jha, A., Langan, L., Owen, S., Trznadel, M., Dodd, N., Jackson, S., & Purcell, W. (2018) 'Spheroid Size Does not Impact Metabolism of the beta-blocker Propranolol in 3D Intestinal Fish Model', Frontiers in Pharmacology, 9. Available at: 10.3389/fphar.2018.00947