The Plymouth Student Scientist
Document Type
Literature Review
Abstract
Green fluorescent protein was first discovered in Aequorea victoria. Its significance in a continually expanding range of scientific applications led to the discovery of an abundance of homologous fluorescent proteins and non-fluorescent chromoproteins in a variety of species in the phylum Cnidaria. The document reviews the various proposed hypotheses on the biological functions and biochemistry of fluorescent proteins and chromoproteins, wherein a full resolution remains elusive and is the subject of on-going debate. Mutagenesis has provided novel variants and insights into the relationship between the spectral characteristics and chromophore structures of fluorescent proteins that encompass the visible spectrum. Fluorescent proteins as genetically encoded reporters have revealed important aspects of cellular biology and physiology that would have been unobtainable using traditional in vitro methods. The development of fluorescent proteins has opened up numerous possibilities for novel imaging techniques using living cells.
Publication Date
2012-12-01
Publication Title
The Plymouth Student Scientist
Volume
5
Issue
2
First Page
544
Last Page
557
ISSN
1754-2383
Deposit Date
2019-05-15
Embargo Period
2024-07-11
URI
http://hdl.handle.net/10026.1/13999
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
Recommended Citation
Lewis, Mario
(2012)
"Fluorescent proteins and chromoproteins in phylum: Cnidaria,"
The Plymouth Student Scientist: Vol. 5:
Iss.
2, Article 5.
Available at:
https://pearl.plymouth.ac.uk/tpss/vol5/iss2/5
Included in
Engineering Commons, Physical Sciences and Mathematics Commons, Psychiatry and Psychology Commons
