ORCID
- Matthew E. Roser: 0000-0001-6322-9863
Abstract
This study was to investigate the relationship between the ventral caudate connectivity and anhedonia. Nineteen depressed patients and 16 healthy controls participated in two identical functional magnetic resonance imaging scans during a 1-year period to determine the resting-state functional connectivity changes using a seed-based approach. Patients showed increased left ventral caudate functional connectivity with superior frontal gyrus over time and the increased connectivity was associated with anhedonia improvement. None of these associations were observed in healthy controls. The findings suggest that left ventral caudate may serve as a potential target to improve the severity of anhedonia.
DOI Link
Publication Date
2022-05-04
Publication Title
Journal of Psychiatric Research
Volume
151
ISSN
0022-3956
Acceptance Date
2022-04-25
Deposit Date
2022-03-05
Embargo Period
2023-05-04
Funding
This study was supported by the Natural Science Foundation of Hunan Province (2019JJ40118), the CAS Key Laboratory of Mental Health of the Institute of Psychology to JH. The funding agents had no role in study design, collection, analysis and writing.
Keywords
Anhedonia, Ventral caudate, Superior frontal gyrus
First Page
286
Last Page
290
Recommended Citation
Yang, X., Huang, J., Roser, M., & Guangrong, X. (2022) 'Anhedonia reduction correlates with increased ventral caudate connectivity with superior frontal gyrus in depression.', Journal of Psychiatric Research, 151, pp. 286-290. Available at: 10.1016/j.jpsychires.2022.04.030
