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Abstract

We present a novel toolbox to generate computed tomography (CT) images from anatomical T1-weighted magnetic resonance (MR) images for use in planning transcranial ultrasound stimulation (TUS) studies in humans (https://github.com/sitiny/mr-topct). Our validated open-source toolbox is aimed at researchers interested in generating bespoke skull models for use in acoustic simulations in TUS studies. Importantly, researchers planning TUS studies will most likely already have access to standard T1-weighted MR images for neuronavigation, making our toolbox compatible with many existing protocols for TUS studies

Publication Date

2023-01-17

Publication Title

Brain Stimulation

Volume

16

Issue

1

ISSN

1935-861X

Acceptance Date

2023-01-14

Deposit Date

2023-02-13

Embargo Period

2023-02-14

Funding

E.F. and S.N.Y. are supported by the UKRI/MRC grant MR/T023007/1. This work was supported by the UK Department of Health via the NIHR Comprehensive Biomedical Research Centre Award (COV-LT-0009) to Guy's and St Thomas' NHS Foundation Trust (in partnership with King's College London and King's College Hospital NHS Foundation Trust), and by the Wellcome Engineering and Physical Sciences Research Council Centre for Medical Engineering at King's College London (WT 203148/Z/16/Z). CERMEP-IDB-MRXFDG Database (© Copyright CERMEP – Imagerie du vivant, www.cermep.fr and Hospices Civils de Lyon. All rights reserved.) provided jointly by CERMEP and Hospices Civils de Lyon (HCL) under free academic end user licence agreement.

Keywords

Non-invasive brain stimulation, Acoustic simulation, Multi-element transducer, Deep learning, Image synthesis, U-Net

Creative Commons License

Creative Commons Attribution 4.0 International License
This work is licensed under a Creative Commons Attribution 4.0 International License.

First Page

75

Last Page

78

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