ORCID
- Stephen Mullin: 0000-0002-1936-394X
Document Type
Article
Abstract
The genetic landscape of Parkinson’s disease (PD) is characterised by rare high penetrance pathogenic variants causing familial disease, genetic risk factor variants driving PD risk in a significant minority in PD cases and high frequency, low penetrance variants, which contribute a small increase of the risk of developing sporadic PD. This knowledge has the potential to have a major impact in the clinical care of people with PD. We summarise these genetic influences and discuss the implications for therapeutics and clinical trial design.
DOI Link
Publication Date
2021-06-30
Publication Title
Genes
Volume
12
Issue
7
ISSN
2073-4425
Acceptance Date
2021-06-28
Deposit Date
2021-02-07
Embargo Period
2021-07-06
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
First Page
1006
Last Page
1006
Recommended Citation
Day, J., & Mullin, S. (2021) 'The Genetics of Parkinson’s Disease and Implications for Clinical Practice', Genes, 12(7), pp. 1006-1006. Available at: 10.3390/genes12071006
