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Abstract

EditorialsA holistic approach is needed for the treatment of alcohol use disorderKronsten, Victoria T.1; Dhanda, Ashwin2Author Information1Faculty of Life Sciences and Medicine, School of Immunology and Microbial Sciences, Roger Williams Institute of Liver Studies, King’s College London, London, UK2Faculty of Health, School of Immunology and Microbial Sciences, University of Plymouth, Plymouth, UKAbbreviations: AUD, alcohol use disorder; AUDIT-C, Alcohol Use Disorders Identification Test— Consumption; EtG, ethyl glucuronide.Correspondence Victoria T. Kronsten, Faculty of Life Sciences and Medicine, School of Immunology and Microbial Sciences, Roger Williams Institute of Liver Studies, King’s College London, London, UK. Email: victoria.kronsten@nhs.netLiver Transplantation 31(6):p 699-700, June 2025. | DOI: 10.1097/LVT.0000000000000588FreeCorresponding ArticleAlcohol is one of the most frequently used addictive substances worldwide, and its use carries an alarmingly high health, social, and economic burden. In 2019, alcohol consumption was accountable for 4.7% of all global deaths.1 Long-term alcohol use contributes to over 200 diseases and causes 7 cancers.2 Alcohol use disorder (AUD) is a common, chronic and relapsing condition affecting 7% of the world’s population aged 15 years and older,1 and is characterized by the inability to stop drinking or impaired control despite negative social, occupational, or health outcomes. Alcohol cessation is challenging for many patients; however, it is paramount to prevent long-term negative health consequences. While treatment for AUD can be very effective, access to specialist pharmacotherapy, mental health, and addiction services is limited; only 10% of patients with alcohol-associated liver disease are seen in a specialty mental health or addiction clinic, and 0.8% are prescribed medication for AUD in the United States.3 Understanding predictors of behavioral change in patients with AUD is therefore of utmost importance in order to ensure that patients requiring increased alcohol cessation support are identified.

Publication Date

2025-06-01

Publication Title

Liver Transplantation

Volume

31

Issue

6

ISSN

1527-6465

Acceptance Date

2025-02-18

Deposit Date

2026-01-15

First Page

699

Last Page

700

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