IFN-λ3, not IFN-λ4, likely mediates IFNL3-IFNL4 haplotype-dependent hepatic inflammation and fibrosis

Authors

Jacob George, University of Sydney
Mohammed Eslam, University of Sydney
Duncan McLeod, Westmead Hospital
Kebitsaone Simon Kelaeng, University of Sydney
Alessandra Mangia, IRCCS Ospedale Casa Sollievo della Sofferenza - San Giovanni Rotondo (FG)
Thomas Berg, Leipzig University
Khaled Thabet, Minia University
William L. Irving, University of Nottingham
Gregory J. Dore, University of New South Wales
David Sheridan, Peninsula Medical School
Henning Grønbæk, Aarhus University
Maria Lorena Abate, University of Turin
Rune Hartmann, Aarhus University
Elisabetta Bugianesi, University of Turin
Ulrich Spengler, University of Bonn
Angela Rojas, Hospital Universitario Virgen del Rocio
David R. Booth, University of Sydney
Martin Weltman, Nepean Hospital
Lindsay Mollison, Fremantle Hospital
Wendy Cheng, Royal Perth Hospital
Stephen Riordan, University of New South Wales
H Mahajan
Janett Fischer, Leipzig University
Jacob Nattermann, University of Bonn
Mark W. Douglas, University of Sydney
Christopher Liddle, University of Sydney
Elizabeth Powell, University of Queensland
Manuel Romero-Gomez, Hospital Universitario Virgen del Rocio
Mayada Metwally, University of Sydney
Rose White, University of Sydney
Rocio Gallego-Duran
Reynold Leung
N Mahajan
Margaret Bassendine
Antony Rahme
Chiara Rosso
Lavinia Mezzabotta
Barbara Malik
Gail Matthews
Anastasia Asimakopoulos
Tanya Applegate
Jason Grebely
Vincenzo Fragomeli
Julie R. Jonsson
Rosanna Santoro

ORCID

• David Sheridan: 0000-0001-5100-814X

DOI Link

10.1038/ng.3836

DOI

10.1038/ng.3836

Publication Date

2017-04-10

Publication Title

Nature Genetics

Volume

49

Issue

5

ISSN

1061-4036

Embargo Period

2017-10-10

First Page

795

Last Page

800

Recommended Citation

George, J., Eslam, M., McLeod, D., Kelaeng, K., Mangia, A., Berg, T., Thabet, K., Irving, W., Dore, G., Sheridan, D., Grønbæk, H., Abate, M., Hartmann, R., Bugianesi, E., Spengler, U., Rojas, A., Booth, D., Weltman, M., Mollison, L., Cheng, W., Riordan, S., Mahajan, H., Fischer, J., Nattermann, J., Douglas, M., Liddle, C., Powell, E., Romero-Gomez, M., Metwally, M., White, R., Gallego-Duran, R., Leung, R., Mahajan, N., Bassendine, M., Rahme, A., Rosso, C., Mezzabotta, L., Malik, B., Matthews, G., Asimakopoulos, A., Applegate, T., Grebely, J., Fragomeli, V., Jonsson, J., & Santoro, R. (2017) 'IFN-λ3, not IFN-λ4, likely mediates IFNL3-IFNL4 haplotype-dependent hepatic inflammation and fibrosis', Nature Genetics, 49(5), pp. 795-800. Available at: 10.1038/ng.3836