Sevoflurane sedation – blind alley or cunning plan?
ORCID
- J Robert Sneyd: 0000-0003-3546-9856
Abstract
Low-dose inhaled sevoflurane sedation impaired volunteers' ability to complete a button-press task, without significant cardiorespiratory compromise. Patient-controlled sedation using sevoflurane might be feasible, however regulatory hurdles require proof of safety and efficacy through clinical trials. Whilst a promising concept, it must be demonstrated that patients cannot induce unconsciousness on their own, despite any interactions with opioid analgesics. Significant steps remain before practical, patient-controlled sevoflurane sedation can be implemented.
Publication Date
2025-03-26
Publication Title
British Journal of Anaesthesia
ISSN
0007-0912
Embargo Period
2026-03-26
Keywords
anaesthesia equipment, inhalation anaesthesia, methoxyflurane, procedural sedation, reaction time, sevoflurane
Recommended Citation
Sneyd, J., & Absalom, A. (2025) 'Sevoflurane sedation – blind alley or cunning plan?', British Journal of Anaesthesia, . Available at: 10.1016/j.bja.2025.02.026
