Sevoflurane sedation – blind alley or cunning plan?

ORCID

Abstract

Low-dose inhaled sevoflurane sedation impaired volunteers' ability to complete a button-press task, without significant cardiorespiratory compromise. Patient-controlled sedation using sevoflurane might be feasible, however regulatory hurdles require proof of safety and efficacy through clinical trials. Whilst a promising concept, it must be demonstrated that patients cannot induce unconsciousness on their own, despite any interactions with opioid analgesics. Significant steps remain before practical, patient-controlled sevoflurane sedation can be implemented.

Publication Date

2025-02-26

Publication Title

British Journal of Anaesthesia

ISSN

0007-0912

Embargo Period

9999-12-31

This document is currently not available here.

This item is under embargo until 31 December 9999

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