ORCID
- J. Robert Sneyd: 0000-0003-3546-9856
Abstract
Rapid elimination of remifentanil facilitates application of intense opioid effect during general anaesthesia whilst maintaining prompt emergence. Interruptions in remifentanil supply mean clinicians must relearn titration of pharmacokinetically longer-acting opioids to achieve appropriate levels of opioid effect whilst maintaining acceptable recovery times. Opioid-free anaesthesia is achievable for many minor and intermediate surgical procedures for which remifentanil might have been used previously.
DOI
10.1016/j.bja.2022.08.001
Publication Date
2022-01-01
Publication Title
British Journal of Anaesthesia
Volume
129
Issue
5
ISSN
0007-0912
Keywords
alfentanil, pharmacodynamics, pharmacokinetics, propofol, remifentanil, supply chain
First Page
649
Last Page
651
Recommended Citation
Sneyd, J. (2022) 'Potential responses to remifentanil supply shortages', British Journal of Anaesthesia, 129(5), pp. 649-651. Available at: https://doi.org/10.1016/j.bja.2022.08.001
