ORCID
- J. Robert Sneyd: 0000-0003-3546-9856
Abstract
Intensive care unit (ICU) sedation with sevoflurane is associated with nephrogenic diabetes insipidus. Given that isoflurane is now licenced (in Europe) for ICU sedation and has Investigational New Drug status in the USA, evidence indicates that clinicians should stop using sevoflurane in this indication except in the context of clinical trials.
DOI
10.1016/j.bja.2022.02.031
Publication Date
2022-01-01
Publication Title
British Journal of Anaesthesia
Volume
129
Issue
1
ISSN
0007-0912
Keywords
acute kidney injury, diabetes insipidus, isoflurane, nephrotoxicity, sedation, sevoflurane
First Page
7
Last Page
10
Recommended Citation
Sneyd, J. (2022) 'Avoiding kidney damage in ICU sedation with sevoflurane: use isoflurane instead', British Journal of Anaesthesia, 129(1), pp. 7-10. Available at: https://doi.org/10.1016/j.bja.2022.02.031
