Abstract
OBJECTIVE:: To examine the feasibility of a trial to evaluate web-based physiotherapy compared to a standard home exercise programme in people with multiple sclerosis. DESIGN:: Multi-centre, randomized controlled, feasibility study. SETTING:: Three multiple sclerosis out-patient centres. PARTICIPANTS:: A total of 90 people with multiple sclerosis (Expanded Disability Status Scale 4-6.5). INTERVENTIONS:: Participants were randomized to a six-month individualized, home exercise programme delivered via web-based physiotherapy ( n = 45; intervention) or a sheet of exercises ( n = 45; active comparator). OUTCOME MEASURES:: Outcome measures (0, three, six and nine months) included adherence, two-minute walk test, 25 foot walk, Berg Balance Scale, physical activity and healthcare resource use. Interviews were undertaken with 24 participants and 3 physiotherapists. RESULTS:: Almost 25% of people approached agreed to take part. No intervention-related adverse events were recorded. Adherence was 40%-63% and 53%-71% in the intervention and comparator groups. There was no difference in the two-minute walk test between groups at baseline (Intervention-80.4(33.91)m, Comparator-70.6(31.20)m) and no change over time (at six-month Intervention-81.6(32.75)m, Comparator-74.8(36.16)m. There were no significant changes over time in other outcome measures except the EuroQol-5 Dimension at six months which decreased in the active comparator group. For a difference of 8(17.4)m in two-minute walk test between groups, 76 participants/group would be required (80% power, P > 0.05) for a future randomized controlled trial. CONCLUSION:: No changes were found in the majority of outcome measures over time. This study was acceptable and feasible by participants and physiotherapists. An adequately powered study needs 160 participants.
DOI
10.1177/0269215518817080
Publication Date
2018-12-04
Publication Title
Clinical Rehabilitation
First Page
269215518817080
Last Page
269215518817080
ISSN
0269-2155
Embargo Period
2019-01-25
Organisational Unit
School of Health Professions
Keywords
Internet, Physiotherapy, exercise, multiple sclerosis
Recommended Citation
Paul, L., Renfrew, L., Freeman, J., Murray, H., Weller, B., Mattison, P., McConnachie, A., Heggie, R., Wu, O., & Coulter, E. (2018) 'Web-based physiotherapy for people affected by multiple sclerosis: a single blind, randomized controlled feasibility study.', Clinical Rehabilitation, , pp. 269215518817080-269215518817080. Available at: https://doi.org/10.1177/0269215518817080
