Management of CSF leak in base of skull fractures in adults
dc.contributor.author | Phang, SY | |
dc.contributor.author | Whitehouse, K | |
dc.contributor.author | Lee, L | |
dc.contributor.author | Khalil, Hisham | |
dc.contributor.author | McArdle, P | |
dc.contributor.author | Whitfield, Peter | |
dc.date.accessioned | 2016-11-23T22:20:58Z | |
dc.date.available | 2016-11-23T22:20:58Z | |
dc.date.issued | 2016-11 | |
dc.identifier.issn | 0268-8697 | |
dc.identifier.issn | 1360-046X | |
dc.identifier.uri | http://hdl.handle.net/10026.1/7547 | |
dc.description | peerreview_statement: The publishing and review policy for this title is described in its Aims & Scope. aims_and_scope_url: http://www.tandfonline.com/action/journalInformation?show=aimsScope&journalCode=ibjn20 | |
dc.description.abstract |
AIMS: CSF leaks are not uncommon after a base of skull fracture. Currently there is no standardised algorithm for the investigation and management of post-traumatic CSF leaks. In this paper we aim to provide an evidence-based framework for managing post-traumatic CSF leaks. METHODS: We searched the English literature over the past 45 years using CINAHL, EMBASE and MEDLINE for the terms (1) post-traumatic CSF leaks or fistulas, and (2) basilar or base of skull fractures, but excluded papers on post-operative and non-traumatic CSF leaks, and papers on paediatric post- traumatic CSF leaks. RESULTS: The diagnosis of a base of skull fracture and any resultant CSF leak can be challenging. Therefore a combination of biochemical and radiological studies are needed to optimise the diagnosis of this condition. Post-traumatic CSF leaks are generally treated conservatively, and a majority of them resolve without further surgical management. However for patients who are refractory to such treatments, surgical closure of the CSF fistula is necessary. Surgical obliteration of CSF leaks can be challenging and requires the involvement of multiple surgical specialties such as neurosurgery, otolaryngology, and maxillofacial surgery. CONCLUSION: Although we have formulated a simple algorithm to aid the investigation and management of post-traumatic CSF leaks, there are still many important unresolved questions requiring further well powered studies to answer. | |
dc.format.extent | 596-604 | |
dc.format.medium | Print-Electronic | |
dc.language | en | |
dc.language.iso | en | |
dc.publisher | Informa UK Limited | |
dc.subject | Cerebrospinal fluid | |
dc.subject | treatment | |
dc.subject | skull fracture | |
dc.subject | surgical management | |
dc.title | Management of CSF leak in base of skull fractures in adults | |
dc.type | journal-article | |
dc.type | Journal Article | |
dc.type | Meta-Analysis | |
dc.type | Review | |
plymouth.author-url | https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000386910900003&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=11bb513d99f797142bcfeffcc58ea008 | |
plymouth.issue | 6 | |
plymouth.volume | 30 | |
plymouth.publication-status | Published | |
plymouth.journal | British Journal of Neurosurgery | |
dc.identifier.doi | 10.1080/02688697.2016.1229746 | |
plymouth.organisational-group | /Plymouth | |
plymouth.organisational-group | /Plymouth/Faculty of Health | |
plymouth.organisational-group | /Plymouth/Faculty of Health/Peninsula Medical School | |
plymouth.organisational-group | /Plymouth/REF 2021 Researchers by UoA | |
plymouth.organisational-group | /Plymouth/REF 2021 Researchers by UoA/UoA01 Clinical Medicine | |
plymouth.organisational-group | /Plymouth/Users by role | |
plymouth.organisational-group | /Plymouth/Users by role/Academics | |
dc.publisher.place | England | |
dcterms.dateAccepted | 2016-08-22 | |
dc.rights.embargodate | 2017-9-26 | |
dc.identifier.eissn | 1360-046X | |
dc.rights.embargoperiod | Not known | |
rioxxterms.versionofrecord | 10.1080/02688697.2016.1229746 | |
rioxxterms.licenseref.uri | http://www.rioxx.net/licenses/all-rights-reserved | |
rioxxterms.licenseref.startdate | 2016-11 | |
rioxxterms.type | Journal Article/Review |