Molecular genetic studies of neurodegenerative disease.
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Large scale genetic studies such as genome-wide association studies (GWAS) in Parkinson's disease (PD) have revealed genetic susceptibility factors and continue to offer new insights both into the genetics of sporadic disease and its pathogenesis, with the potential for identification of an at-risk population and novel therapeutic targets. However, the methodology importantly requires larger data sets for replication of novel findings.
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