Prioritizing progressive MS rehabilitation research: A call from the International Progressive MS Alliance
dc.contributor.author | Zackowski, KM | |
dc.contributor.author | Freeman, Jennifer | |
dc.contributor.author | Brichetto, G | |
dc.contributor.author | Centonze, D | |
dc.contributor.author | Dalgas, U | |
dc.contributor.author | DeLuca, J | |
dc.contributor.author | Ehde, D | |
dc.contributor.author | Elgott, S | |
dc.contributor.author | Fanning, V | |
dc.contributor.author | Feys, P | |
dc.contributor.author | Finlayson, M | |
dc.contributor.author | Gold, SM | |
dc.contributor.author | Inglese, M | |
dc.contributor.author | Marrie, RA | |
dc.contributor.author | Ploughman, M | |
dc.contributor.author | Sang, CN | |
dc.contributor.author | Sastre-Garriga, J | |
dc.contributor.author | Sincock, C | |
dc.contributor.author | Strum, J | |
dc.contributor.author | van Beek, J | |
dc.contributor.author | Feinstein, A | |
dc.date.accessioned | 2021-04-27T07:54:27Z | |
dc.date.available | 2021-04-27T07:54:27Z | |
dc.date.issued | 2021-03-15 | |
dc.identifier.issn | 1352-4585 | |
dc.identifier.issn | 1477-0970 | |
dc.identifier.uri | http://hdl.handle.net/10026.1/17072 | |
dc.description.abstract |
<jats:sec><jats:title>Background:</jats:title><jats:p> People with multiple sclerosis (MS) experience myriad symptoms that negatively affect their quality of life. Despite significant progress in rehabilitation strategies for people living with relapsing-remitting MS (RRMS), the development of similar strategies for people with progressive MS has received little attention. </jats:p></jats:sec><jats:sec><jats:title>Objective:</jats:title><jats:p> To highlight key symptoms of importance to people with progressive MS and stimulate the design and implementation of high-quality studies focused on symptom management and rehabilitation. </jats:p></jats:sec><jats:sec><jats:title>Methods:</jats:title><jats:p> A group of international research experts, representatives from industry, and people affected by progressive MS was convened by the International Progressive MS Alliance to devise research priorities for addressing symptoms in progressive MS. </jats:p></jats:sec><jats:sec><jats:title>Results:</jats:title><jats:p> Based on information from the MS community, we outline a rationale for highlighting four symptoms of particular interest: fatigue, mobility and upper extremity impairment, pain, and cognitive impairment. Factors such as depression, resilience, comorbidities, and psychosocial support are described, as they affect treatment efficacy. </jats:p></jats:sec><jats:sec><jats:title>Conclusions:</jats:title><jats:p> This coordinated call to action—to the research community to prioritize investigation of effective symptom management strategies, and to funders to support them—is an important step in addressing gaps in rehabilitation research for people affected by progressive MS. </jats:p></jats:sec> | |
dc.format.extent | 135245852199997-135245852199997 | |
dc.format.medium | Print-Electronic | |
dc.language | en | |
dc.language.iso | en | |
dc.publisher | SAGE Publications | |
dc.subject | Symptoms | |
dc.subject | fatigue | |
dc.subject | mobility | |
dc.subject | upper extremity impairment | |
dc.subject | pain | |
dc.subject | cognition | |
dc.title | Prioritizing progressive MS rehabilitation research: A call from the International Progressive MS Alliance | |
dc.type | journal-article | |
dc.type | Journal Article | |
plymouth.author-url | https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000652834300003&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=11bb513d99f797142bcfeffcc58ea008 | |
plymouth.issue | 7 | |
plymouth.volume | 27 | |
plymouth.publication-status | Published | |
plymouth.journal | Multiple Sclerosis Journal | |
dc.identifier.doi | 10.1177/1352458521999970 | |
plymouth.organisational-group | /Plymouth | |
plymouth.organisational-group | /Plymouth/Faculty of Health | |
plymouth.organisational-group | /Plymouth/Faculty of Health/School of Health Professions | |
plymouth.organisational-group | /Plymouth/REF 2021 Researchers by UoA | |
plymouth.organisational-group | /Plymouth/REF 2021 Researchers by UoA/UoA03 Allied Health Professions, Dentistry, Nursing and Pharmacy | |
plymouth.organisational-group | /Plymouth/Research Groups | |
plymouth.organisational-group | /Plymouth/Research Groups/Institute of Health and Community | |
plymouth.organisational-group | /Plymouth/Research Groups/Plymouth Institute of Health and Care Research (PIHR) | |
plymouth.organisational-group | /Plymouth/Users by role | |
plymouth.organisational-group | /Plymouth/Users by role/Academics | |
plymouth.organisational-group | /Plymouth/Users by role/Researchers in ResearchFish submission | |
dc.publisher.place | England | |
dcterms.dateAccepted | 2021-02-07 | |
dc.rights.embargodate | 2021-4-28 | |
dc.identifier.eissn | 1477-0970 | |
dc.rights.embargoperiod | Not known | |
rioxxterms.versionofrecord | 10.1177/1352458521999970 | |
rioxxterms.licenseref.uri | http://www.rioxx.net/licenses/all-rights-reserved | |
rioxxterms.licenseref.startdate | 2021-03-15 | |
rioxxterms.type | Journal Article/Review |