Effect of phenylephrine on static and dynamic accommodation.
dc.contributor.author | Del Águila-Carrasco, AJ | en |
dc.contributor.author | Lara, F | en |
dc.contributor.author | Bernal-Molina, P | en |
dc.contributor.author | Riquelme-Nicolás, R | en |
dc.contributor.author | Marín-Franch, I | en |
dc.contributor.author | Esteve-Taboada, JJ | en |
dc.contributor.author | Montés-Micó, R | en |
dc.contributor.author | Kruger, PB | en |
dc.contributor.author | López-Gil, N | en |
dc.date.accessioned | 2018-09-20T17:47:38Z | |
dc.date.available | 2018-09-20T17:47:38Z | |
dc.date.issued | 2019-01 | en |
dc.identifier.uri | http://hdl.handle.net/10026.1/12399 | |
dc.description.abstract |
PURPOSE: We tested the hypothesis that changes in accommodation after instillation of Phenylephrine Hydrochloride (PHCl) observed in some studies could be caused by changes in optics. METHODS: We performed two experiments to test the effects of PHCl on static and on dynamic accommodation in 8 and 6 subjects, respectively. Objective wavefront measurements were recorded of the static accommodation response to a stimulus at different distances or dynamic accommodation response to a sinusoidally moving stimulus (between 1 and 3 D of accommodative demand at 0.2Hz). The responses were characterized using two methods: one that takes into account the mydriatic optical effects on the accommodation produced by higher-order aberrations of the eye and another that takes into account only power changes paraxially due to the action of the ciliary muscle and regardless of the pupil size. RESULTS: When mydriatic optical effects were taken into account, differences in responses before and after PHCl instillation were 0.51±0.53 D, and 0.12±0.15, for static and dynamic accommodation, respectively, and were statistically significant (p<0.039). When mydriatic optical effects were not taken into account, the differences in responses before and after PHCl instillation were -0.20±0.51 D, and -0.05±0.14, for static and dynamic accommodation, respectively, and were not statistically significant (p>0.313). CONCLUSIONS: The mydriatic effect of the PHCl causes optical changes in the eye that can reduce the objective and subjective measurement of accommodation. | en |
dc.format.extent | 30 - 37 | en |
dc.language | eng | en |
dc.language.iso | eng | en |
dc.subject | Accommodation | en |
dc.subject | Acomodación | en |
dc.subject | Fenilefrina | en |
dc.subject | Metrics | en |
dc.subject | Métrica | en |
dc.subject | Phenylephrine | en |
dc.subject | Accommodation, Ocular | en |
dc.subject | Adult | en |
dc.subject | Ciliary Body | en |
dc.subject | Female | en |
dc.subject | Humans | en |
dc.subject | Male | en |
dc.subject | Mydriatics | en |
dc.subject | Phenylephrine | en |
dc.title | Effect of phenylephrine on static and dynamic accommodation. | en |
dc.type | Journal Article | |
plymouth.author-url | https://www.ncbi.nlm.nih.gov/pubmed/29602687 | en |
plymouth.issue | 1 | en |
plymouth.volume | 12 | en |
plymouth.publication-status | Published | en |
plymouth.journal | J Optom | en |
dc.identifier.doi | 10.1016/j.optom.2018.01.005 | en |
plymouth.organisational-group | /Plymouth | |
plymouth.organisational-group | /Plymouth/Faculty of Health | |
plymouth.organisational-group | /Plymouth/Faculty of Health/School of Health Professions | |
plymouth.organisational-group | /Plymouth/REF 2021 Researchers by UoA | |
plymouth.organisational-group | /Plymouth/REF 2021 Researchers by UoA/UoA03 Allied Health Professions, Dentistry, Nursing and Pharmacy | |
plymouth.organisational-group | /Plymouth/Users by role | |
plymouth.organisational-group | /Plymouth/Users by role/Academics | |
dc.publisher.place | Spain | en |
dcterms.dateAccepted | 2018-01-29 | en |
dc.identifier.eissn | 1989-1342 | en |
dc.rights.embargoperiod | Not known | en |
rioxxterms.versionofrecord | 10.1016/j.optom.2018.01.005 | en |
rioxxterms.licenseref.uri | http://www.rioxx.net/licenses/all-rights-reserved | en |
rioxxterms.licenseref.startdate | 2019-01 | en |
rioxxterms.type | Journal Article/Review | en |