A pre–post intervention study of pulmonary rehabilitation for adults with post-tuberculosis lung disease in Uganda
dc.contributor.author | Jones, Rupert | |
dc.contributor.author | Kirenga, BJ | |
dc.contributor.author | Katagira, W | |
dc.contributor.author | Singh, SJ | |
dc.contributor.author | Pooler, Jillian | |
dc.contributor.author | Okwera, A | |
dc.contributor.author | Kasiita, R | |
dc.contributor.author | Enki, Doyo Gragn | |
dc.contributor.author | Creanor, Siobhan | |
dc.contributor.author | barton, andy | |
dc.date.accessioned | 2017-12-11T09:00:12Z | |
dc.date.available | 2017-12-11T09:00:12Z | |
dc.date.issued | 2017-12-11 | |
dc.identifier.issn | 1178-2005 | |
dc.identifier.issn | 1178-2005 | |
dc.identifier.uri | http://hdl.handle.net/10026.1/10396 | |
dc.description.abstract |
SETTING: The study was conducted at Mulago Hospital, Kampala, Uganda. OBJECTIVE: As chronic respiratory disease (CRD) is a huge, growing burden in Africa, with few available treatments, we aimed to design and evaluate a culturally appropriate pulmonary rehabilitation (PR) program in Uganda for people with post-tuberculosis lung disorder (p-TBLD). DESIGN: In a pre-post intervention study, a 6-week, twice-weekly PR program was designed for people with p-TBLD. Outcome measures included recruitment, retention, the Clinical COPD Questionnaire (CCQ), tests of exercise capacity, and biometrics. Given this was a developmental study, no formal statistical significance testing was undertaken. RESULTS: In all, 34 participants started PR and 29 (85%) completed all data collection. The mean age of the 29 participants was 45 years, and 52% were female. The mean (95% confidence interval) CCQ score at baseline was 1.8 (1.5, 2.0), at the end of PR was 1.0 (0.8, 1.2), and at 6 weeks after the end of PR was 0.8 (0.7, 1.0). The Incremental Shuttle Walking Test (ISWT) was 299 m (268.5, 329.4) at baseline, 377 (339.6, 413.8) at the end of PR, and 374 (334.2, 413.5) at 6 weeks after the end of PR. Improvements were seen in measures of chest pain; 13/29 (45%) participants reported chest pain at baseline but only 7/29 (24%) at the end of PR, and in those with persistent pain, the mean pain scores decreased. Mild hemoptysis was reported in 4/29 (17%) participants at baseline and in 2/29 (7%) at the end of PR. CONCLUSION: PR for people with p-TBLD in Uganda was feasible and associated with clinically important improvements in quality of life, exercise capacity, and respiratory outcomes. PR uses local resources, requires little investment, and offers a new, sustainable therapy for p-TBLD in resource-limited settings. With the rising global burden of CRD, further studies are needed to assess the value of PR in p-TBLD and other prevalent forms of CRD. | |
dc.format.extent | 3533-3539 | |
dc.format.medium | Electronic-eCollection | |
dc.language | en | |
dc.language.iso | en | |
dc.publisher | Dove Medical Press | |
dc.subject | tuberculosis | |
dc.subject | exercise training | |
dc.subject | self-management | |
dc.subject | nonpharmacological intervention | |
dc.title | A pre–post intervention study of pulmonary rehabilitation for adults with post-tuberculosis lung disease in Uganda | |
dc.type | journal-article | |
dc.type | Journal Article | |
dc.type | Video-Audio Media | |
plymouth.author-url | https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000417594300001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=11bb513d99f797142bcfeffcc58ea008 | |
plymouth.volume | Volume 12 | |
plymouth.publication-status | Published | |
plymouth.journal | International Journal of Chronic Obstructive Pulmonary Disease | |
dc.identifier.doi | 10.2147/COPD.S146659 | |
plymouth.organisational-group | /Plymouth | |
plymouth.organisational-group | /Plymouth/Faculty of Health | |
plymouth.organisational-group | /Plymouth/Faculty of Health/Peninsula Medical School | |
plymouth.organisational-group | /Plymouth/Faculty of Health/Peninsula Medical School/PMS - Manual | |
plymouth.organisational-group | /Plymouth/REF 2021 Researchers by UoA | |
plymouth.organisational-group | /Plymouth/REF 2021 Researchers by UoA/UoA03 Allied Health Professions, Dentistry, Nursing and Pharmacy | |
plymouth.organisational-group | /Plymouth/REF 2021 Researchers by UoA/UoA03 Allied Health Professions, Dentistry, Nursing and Pharmacy/UoA03 Allied Health Professions, Dentistry, Nursing and Pharmacy MANUAL | |
plymouth.organisational-group | /Plymouth/Research Groups | |
plymouth.organisational-group | /Plymouth/Research Groups/FoH - Community and Primary Care | |
plymouth.organisational-group | /Plymouth/Research Groups/Institute of Health and Community | |
plymouth.organisational-group | /Plymouth/Research Groups/Institute of Translational and Stratified Medicine (ITSMED) | |
plymouth.organisational-group | /Plymouth/Research Groups/Institute of Translational and Stratified Medicine (ITSMED)/CBBB | |
plymouth.organisational-group | /Plymouth/Research Groups/Institute of Translational and Stratified Medicine (ITSMED)/CCT&PS | |
plymouth.organisational-group | /Plymouth/Users by role | |
plymouth.organisational-group | /Plymouth/Users by role/Academics | |
dc.publisher.place | New Zealand | |
dcterms.dateAccepted | 2017-09-07 | |
dc.identifier.eissn | 1178-2005 | |
dc.rights.embargoperiod | Not known | |
rioxxterms.versionofrecord | 10.2147/COPD.S146659 | |
rioxxterms.licenseref.uri | http://www.rioxx.net/licenses/all-rights-reserved | |
rioxxterms.licenseref.startdate | 2017-12-11 | |
rioxxterms.type | Journal Article/Review | |
plymouth.funder | A development study to examine feasibility and acceptability of pulmonary rehabilitation in Uganda for adults with chronic respiratory disease::MRC |