Abstract
Cholinesterases (ChE) are specialized carboxylic ester hydrolases that catalyse the hydrolysis of choline esters. They are classified into either acetylcholinesterase (AChE) or butyrylcholinesterase (BChE). Determination of ChE in the tissues is the appropriate tool for the diagnosis of organophosphorus and carbamate exposures. In general, a significant inhibition was seen in both AChE and BChE activities after 6 months of freezing at -80°C and after 3 months of freezing at -20°C. Linear regression of mean AChE and BChE was observed in all individual samples during the months of the two freezing methods. Bland and Altman plot of the ratios of the two freezing methods have showen the mean difference between the two freezing methods to be 8.8, and SD was 144.7 and -127.6 for upper and lower limits, respectively, for liver, while in muscle the mean difference was 1.5 and SD was 32.5 and -28.9 for upper and lower limits, respectively.
DOI
10.4061/2010/904249
Publication Date
2010-01-17
Publication Title
Enzyme Research
Volume
2010
Publisher
Hindawi Limited
ISSN
2090-0414
Embargo Period
2024-11-22
First Page
1
Last Page
11
Recommended Citation
Askar, K., Kudi, A., & Moody, A. (2010) 'Comparison of Two Storage Methods for the Analysis of Cholinesterase Activities in Food Animals', Enzyme Research, 2010, pp. 1-11. Hindawi Limited: Available at: https://doi.org/10.4061/2010/904249
