Determining the haemodynamic significance of arterial stenosis: the relationship between CT angiography, computational fluid dynamics, and non-invasive fractional flow reserve
dc.contributor.author | Pang, CL | |
dc.contributor.author | Alcock, R | |
dc.contributor.author | Pilkington, N | |
dc.contributor.author | Reis, T | |
dc.contributor.author | Roobottom, C | |
dc.date.accessioned | 2017-05-26T10:25:57Z | |
dc.date.available | 2017-05-26T10:25:57Z | |
dc.date.issued | 2016-08 | |
dc.identifier.issn | 0009-9260 | |
dc.identifier.issn | 1365-229X | |
dc.identifier.uri | http://hdl.handle.net/10026.1/9361 | |
dc.description | publisher: Elsevier articletitle: Determining the haemodynamic significance of arterial stenosis: the relationship between CT angiography, computational fluid dynamics, and non-invasive fractional flow reserve journaltitle: Clinical Radiology articlelink: http://dx.doi.org/10.1016/j.crad.2016.03.001 content_type: article copyright: © 2016 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved. publicationstatus: published | |
dc.description.abstract |
Coronary artery disease causes significant morbidity and mortality worldwide. Invasive coronary angiography (ICA) is currently the reference standard investigation. Fractional flow reserve (FFR) complements traditional ICA by providing extra information on blood flow, which has convincingly led to better patient management and improved cost-effectiveness. Computed tomography coronary angiography (CTCA) is suitable for the investigation of chest pain, especially in the low- and intermediate-risk groups. FFR generated using CT data (producing FFRCT) may improve the positive predictive value of CTCA. The basic science of FFRCT is like a "black box" to most imaging professionals. A fundamental principle is that good quality CTCA is likely to make any post-processing easier and more reliable. Both diagnostic and observational studies have suggested that the accuracy and the short-term outcome of using FFRCT are both comparable with FFR in ICA. More multidisciplinary research with further refined diagnostic and longer-term observational studies will hopefully pinpoint the role of FFRCT in existing clinical pathways. | |
dc.format.extent | 750-757 | |
dc.format.medium | Print-Electronic | |
dc.language | en | |
dc.language.iso | en | |
dc.publisher | Elsevier BV | |
dc.subject | Computed Tomography Angiography | |
dc.subject | Computer Simulation | |
dc.subject | Coronary Angiography | |
dc.subject | Coronary Stenosis | |
dc.subject | Fractional Flow Reserve, Myocardial | |
dc.subject | Hemorheology | |
dc.subject | Humans | |
dc.subject | Hydrodynamics | |
dc.subject | Models, Cardiovascular | |
dc.subject | Radiographic Image Interpretation, Computer-Assisted | |
dc.title | Determining the haemodynamic significance of arterial stenosis: the relationship between CT angiography, computational fluid dynamics, and non-invasive fractional flow reserve | |
dc.type | journal-article | |
dc.type | article | |
plymouth.author-url | https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000383353400005&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=11bb513d99f797142bcfeffcc58ea008 | |
plymouth.issue | 8 | |
plymouth.volume | 71 | |
plymouth.publication-status | Published | |
plymouth.journal | Clinical Radiology | |
dc.identifier.doi | 10.1016/j.crad.2016.03.001 | |
plymouth.organisational-group | /Plymouth | |
plymouth.organisational-group | /Plymouth/Faculty of Health | |
plymouth.organisational-group | /Plymouth/Faculty of Health/Peninsula Medical School | |
plymouth.organisational-group | /Plymouth/REF 2021 Researchers by UoA | |
plymouth.organisational-group | /Plymouth/REF 2021 Researchers by UoA/UoA01 Clinical Medicine | |
plymouth.organisational-group | /Plymouth/REF 2021 Researchers by UoA/UoA01 Clinical Medicine/UoA01 Clinical Medicine | |
plymouth.organisational-group | /Plymouth/Users by role | |
plymouth.organisational-group | /Plymouth/Users by role/Academics | |
dc.publisher.place | England | |
dcterms.dateAccepted | 2016-03-02 | |
dc.rights.embargodate | 2017-08-01 | |
dc.identifier.eissn | 1365-229X | |
dc.rights.embargoperiod | 12 months | |
rioxxterms.versionofrecord | 10.1016/j.crad.2016.03.001 | |
rioxxterms.licenseref.uri | http://www.rioxx.net/licenses/under-embargo-all-rights-reserved | |
rioxxterms.type | Journal Article/Review |