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dc.contributor.authorLanyon, LJen
dc.contributor.authorDenham, SLen
dc.date.accessioned2017-05-26T08:29:38Z
dc.date.available2017-05-26T08:29:38Z
dc.date.issued2010-06-15en
dc.identifier.urihttp://hdl.handle.net/10026.1/9357
dc.description.abstract

BACKGROUND: Visual neglect is an attentional deficit typically resulting from parietal cortex lesion and sometimes frontal lesion. Patients fail to attend to objects and events in the visual hemifield contralateral to their lesion during visual search. METHODOLOGY/PRINCIPAL FINDING: The aim of this work was to examine the effects of parietal and frontal lesion in an existing computational model of visual attention and search and simulate visual search behaviour under lesion conditions. We find that unilateral parietal lesion in this model leads to symptoms of visual neglect in simulated search scan paths, including an inhibition of return (IOR) deficit, while frontal lesion leads to milder neglect and to more severe deficits in IOR and perseveration in the scan path. During simulations of search under unilateral parietal lesion, the model's extrastriate ventral stream area exhibits lower activity for stimuli in the neglected hemifield compared to that for stimuli in the normally perceived hemifield. This could represent a computational correlate of differences observed in neuroimaging for unconscious versus conscious perception following parietal lesion. CONCLUSIONS/SIGNIFICANCE: Our results lead to the prediction, supported by effective connectivity evidence, that connections between the dorsal and ventral visual streams may be an important factor in the explanation of perceptual deficits in parietal lesion patients and of conscious perception in general.

en
dc.format.extente11128 - ?en
dc.languageengen
dc.language.isoengen
dc.subjectAttentionen
dc.subjectFrontal Lobeen
dc.subjectHumansen
dc.subjectParietal Lobeen
dc.subjectPhotic Stimulationen
dc.subjectVision, Ocularen
dc.titleModelling visual neglect: computational insights into conscious perception.en
dc.typeJournal Article
plymouth.author-urlhttps://www.ncbi.nlm.nih.gov/pubmed/20559559en
plymouth.issue6en
plymouth.volume5en
plymouth.publication-statusPublished onlineen
plymouth.journalPLoS Oneen
dc.identifier.doi10.1371/journal.pone.0011128en
plymouth.organisational-group/Plymouth
plymouth.organisational-group/Plymouth/REF 2021 Researchers by UoA
plymouth.organisational-group/Plymouth/REF 2021 Researchers by UoA/UoA04 Psychology, Psychiatry and Neuroscience
plymouth.organisational-group/Plymouth/Research Groups
plymouth.organisational-group/Plymouth/Research Groups/Centre for Brain, Cognition and Behaviour (CBCB)
plymouth.organisational-group/Plymouth/Research Groups/Centre for Brain, Cognition and Behaviour (CBCB)/Brain
dc.publisher.placeUnited Statesen
dcterms.dateAccepted2010-04-12en
dc.identifier.eissn1932-6203en
dc.rights.embargoperiodNot knownen
rioxxterms.versionofrecord10.1371/journal.pone.0011128en
rioxxterms.licenseref.urihttp://www.rioxx.net/licenses/all-rights-reserveden
rioxxterms.licenseref.startdate2010-06-15en
rioxxterms.typeJournal Article/Reviewen


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