Extracellular Matrix: Functions in the Nervous System
dc.contributor.author | Barros, Claudia | |
dc.contributor.author | Franco, SJ | |
dc.contributor.author | Muller, U | |
dc.date.accessioned | 2016-10-26T21:32:38Z | |
dc.date.available | 2016-10-26T21:32:38Z | |
dc.date.issued | 2011-01-01 | |
dc.identifier.issn | 1943-0264 | |
dc.identifier.issn | 1943-0264 | |
dc.identifier.other | ARTN a005108 | |
dc.identifier.uri | http://hdl.handle.net/10026.1/6646 | |
dc.description.abstract |
An astonishing number of extracellular matrix glycoproteins are expressed in dynamic patterns in the developing and adult nervous system. Neural stem cells, neurons, and glia express receptors that mediate interactions with specific extracellular matrix molecules. Functional studies in vitro and genetic studies in mice have provided evidence that the extracellular matrix affects virtually all aspects of nervous system development and function. Here we will summarize recent findings that have shed light on the specific functions of defined extracellular matrix molecules on such diverse processes as neural stem cell differentiation, neuronal migration, the formation of axonal tracts, and the maturation and function of synapses in the peripheral and central nervous system. | |
dc.format.extent | a005108-a005108 | |
dc.format.medium | Electronic | |
dc.language | en | |
dc.language.iso | eng | |
dc.publisher | Cold Spring Harbor Laboratory | |
dc.subject | Animals | |
dc.subject | Axons | |
dc.subject | Cell Adhesion Molecules, Neuronal | |
dc.subject | Cell Differentiation | |
dc.subject | Cell Movement | |
dc.subject | Extracellular Matrix | |
dc.subject | Extracellular Matrix Proteins | |
dc.subject | Laminin | |
dc.subject | Mice | |
dc.subject | Nerve Tissue Proteins | |
dc.subject | Nervous System | |
dc.subject | Neural Stem Cells | |
dc.subject | Proteoglycans | |
dc.subject | Reelin Protein | |
dc.subject | Serine Endopeptidases | |
dc.subject | Synapses | |
dc.subject | Tenascin | |
dc.title | Extracellular Matrix: Functions in the Nervous System | |
dc.type | journal-article | |
dc.type | Journal Article | |
dc.type | Research Support, N.I.H., Extramural | |
dc.type | Research Support, Non-U.S. Gov't | |
dc.type | Review | |
plymouth.author-url | https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000285866500011&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=11bb513d99f797142bcfeffcc58ea008 | |
plymouth.issue | 1 | |
plymouth.volume | 3 | |
plymouth.publication-status | Published | |
plymouth.journal | Cold Spring Harbor Perspectives in Biology | |
dc.identifier.doi | 10.1101/cshperspect.a005108 | |
plymouth.organisational-group | /Plymouth | |
plymouth.organisational-group | /Plymouth/Faculty of Health | |
plymouth.organisational-group | /Plymouth/Faculty of Health/Peninsula Medical School | |
plymouth.organisational-group | /Plymouth/REF 2021 Researchers by UoA | |
plymouth.organisational-group | /Plymouth/REF 2021 Researchers by UoA/UoA01 Clinical Medicine | |
plymouth.organisational-group | /Plymouth/Users by role | |
plymouth.organisational-group | /Plymouth/Users by role/Academics | |
plymouth.organisational-group | /Plymouth/Users by role/Researchers in ResearchFish submission | |
dc.publisher.place | United States | |
dc.identifier.eissn | 1943-0264 | |
dc.rights.embargoperiod | Not known | |
rioxxterms.versionofrecord | 10.1101/cshperspect.a005108 | |
rioxxterms.licenseref.uri | http://www.rioxx.net/licenses/all-rights-reserved | |
rioxxterms.type | Journal Article/Review | |
plymouth.oa-location | http://cshperspectives.cshlp.org/content/3/1/a005108.full.pdf+html |