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dc.contributor.authorHart, S
dc.contributor.authorHarris, EL
dc.contributor.authorMinutillo, C
dc.contributor.authorWarner, TM
dc.contributor.authorWilliams, Y
dc.contributor.authorDickinson, JE
dc.date.accessioned2016-04-28T15:39:03Z
dc.date.available2016-04-28T15:39:03Z
dc.date.issued2016-04
dc.identifier.urihttp://hdl.handle.net/10026.1/4564
dc.description.abstract

Objectives Previous gastroschisis specific neurodevelopmental studies have focused on the first 3 years of life. The aim of this study was to assess the intellectual, behavioral and neurological outcomes of older children and adolescents born with gastroschisis.

Study design Of 99 gastroschisis survivors born in Western Australia, 1992 to 2005, and who were at least 5 years old, 42 agreed to take part in this study. The study assessed: intellectual ability, with age appropriate Wechsler intelligence scales; neurological status; hearing; vision; behavioral status with the Strengths and Difficulties Questionnaire (SDQ); and parenting style with the Parenting Relationship Questionnaire (PRQ). All results were compared to normative means.

Results Median age at follow-up was 10 years (range 5–17). No child had evidence of cerebral palsy or hearing loss; 1 child had amblyopia. Psychometric tests were completed in 39 children: mean full scale IQ was 98.2 (standard deviation [SD] 10.7); the working memory index was the only subscale to show a significant decrease from the normative mean (mean 95.5, SD 12.4, p = 0.038). The mean SDQ behavioral scores were significantly lower for 3 of 5 domains and the Total Difficulties score. PRQ scores were significantly abnormal for 4 of 7 domains: Communication, Discipline, Satisfaction with School and Relational Frustration.

Conclusions Overall intellectual abilities were within a normal range. The decrease in working memory index and the behavioral and parenting relationship impairments could be an effect of perinatal factors, gastroschisis management and complications or the complexity of the socio-economic environment.

dc.language.isoen
dc.titleThe long term neurodevelopmental and psychological outcomes of gastroschisis: a cohort study evaluation
dc.typejournal-article
plymouth.publication-statusAccepted
plymouth.journalJournal of Paediatric Surgery
dc.identifier.doi10.1016/j.jpedsurg.2015.08.062
plymouth.organisational-group/Plymouth
plymouth.organisational-group/Plymouth/Faculty of Health and Human Sciences
plymouth.organisational-group/Plymouth/Faculty of Health and Human Sciences/School of Nursing and Midwifery
dcterms.dateAccepted2015-08-30
dc.rights.embargoperiodNot known
rioxxterms.versionofrecord10.1016/j.jpedsurg.2015.08.062
rioxxterms.licenseref.urihttp://www.rioxx.net/licenses/all-rights-reserved
rioxxterms.licenseref.startdate2016-04
rioxxterms.typeJournal Article/Review


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