Bio-informatics analysis of a gene co-expression module in adipose tissue containing the diet-responsive gene Nnat.
| dc.contributor.author | Li.X (corresponding author) | en |
| dc.contributor.author | Thomason, PA | en |
| dc.contributor.author | Withers, DJ | en |
| dc.contributor.author | Scott, J | en |
| dc.date.accessioned | 2015-11-26T09:02:09Z | |
| dc.date.available | 2015-11-26T09:02:09Z | |
| dc.date.issued | 2010 | en |
| dc.identifier.uri | http://hdl.handle.net/10026.1/3834 | |
| dc.description | PMCID: PMC3022651 | en |
| dc.description.abstract |
Obesity causes insulin resistance in target tissues - skeletal muscle, adipose tissue, liver and the brain. Insulin resistance predisposes to type-2 diabetes (T2D) and cardiovascular disease (CVD). Adipose tissue inflammation is an essential characteristic of obesity and insulin resistance. Neuronatin (Nnat) expression has been found to be altered in a number of conditions related to inflammatory or metabolic disturbance, but its physiological roles and regulatory mechanisms in adipose tissue, brain, pancreatic islets and other tissues are not understood. | en |
| dc.format.extent | 175 - ? | en |
| dc.language | eng | en |
| dc.language.iso | eng | en |
| dc.subject | Adipose Tissue | en |
| dc.subject | Animals | en |
| dc.subject | Cattle | en |
| dc.subject | Computational Biology | en |
| dc.subject | Diet | en |
| dc.subject | Dogs | en |
| dc.subject | Gene Expression Profiling | en |
| dc.subject | Gene Expression Regulation | en |
| dc.subject | Gene Regulatory Networks | en |
| dc.subject | Genomics | en |
| dc.subject | Humans | en |
| dc.subject | Membrane Proteins | en |
| dc.subject | Mice | en |
| dc.subject | Nerve Tissue Proteins | en |
| dc.subject | Promoter Regions, Genetic | en |
| dc.subject | Protein Interaction Mapping | en |
| dc.subject | Transcription, Genetic | en |
| dc.title | Bio-informatics analysis of a gene co-expression module in adipose tissue containing the diet-responsive gene Nnat. | en |
| dc.type | Journal Article | |
| plymouth.author-url | http://www.ncbi.nlm.nih.gov/pubmed/21187013 | en |
| plymouth.volume | 4 | en |
| plymouth.journal | BMC Syst Biol | en |
| dc.identifier.doi | 10.1186/1752-0509-4-175 | en |
| plymouth.organisational-group | /Plymouth | |
| plymouth.organisational-group | /Plymouth/REF 2021 Researchers by UoA | |
| plymouth.organisational-group | /Plymouth/REF 2021 Researchers by UoA/UoA01 Clinical Medicine | |
| plymouth.organisational-group | /Plymouth/REF 2021 Researchers by UoA/UoA01 Clinical Medicine/UoA01 Clinical Medicine | |
| plymouth.organisational-group | /Plymouth/Research Groups | |
| plymouth.organisational-group | /Plymouth/Research Groups/Institute of Translational and Stratified Medicine (ITSMED) | |
| plymouth.organisational-group | /Plymouth/Research Groups/Institute of Translational and Stratified Medicine (ITSMED)/CBBB | |
| dc.publisher.place | England | en |
| dc.identifier.eissn | 1752-0509 | en |
| dc.rights.embargoperiod | Not known | en |
| rioxxterms.versionofrecord | 10.1186/1752-0509-4-175 | en |
| rioxxterms.licenseref.uri | http://www.rioxx.net/licenses/all-rights-reserved | en |
| rioxxterms.type | Journal Article/Review | en |
