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dc.contributor.authorUssher, M
dc.contributor.authorLewis, S
dc.contributor.authorAveyard, P
dc.contributor.authorManyonda, I
dc.contributor.authorWest, R
dc.contributor.authorLewis, B
dc.contributor.authorMarcus, B
dc.contributor.authorRiaz, M
dc.contributor.authorTaylor, Adrian
dc.contributor.authorDaley, A
dc.contributor.authorColeman, T
dc.date.accessioned2015-11-19T08:58:24Z
dc.date.available2015-11-19T08:58:24Z
dc.date.issued2015-05-14
dc.identifier.issn0959-535X
dc.identifier.issn1756-1833
dc.identifier.otherh2145
dc.identifier.urihttp://hdl.handle.net/10026.1/3818
dc.description.abstract

OBJECTIVE: To determine the effectiveness of a physical activity intervention for smoking cessation during pregnancy. DESIGN: Parallel group, randomised controlled, multicentre trial. SETTING: 13 hospitals in England, April 2009 to January 2014. PARTICIPANTS: 789 pregnant smokers, aged 16-50 years and at 10-24 weeks' gestation, who smoked at least one cigarette daily and were prepared to quit smoking one week after enrollment were randomised (1:1); 785 were included in the intention to treat analyses, with 392 assigned to the physical activity group. INTERVENTIONS: Interventions began one week before a target quit date. Participants were randomised to six weekly sessions of behavioural support for smoking cessation (control) or to this support plus 14 sessions combining supervised treadmill exercise and physical activity consultations. MAIN OUTCOME MEASURES: The primary outcome was continuous smoking abstinence from the target quit date until end of pregnancy, validated by exhaled carbon monoxide or salivary cotinine levels. To assess adherence, levels of moderate-vigorous intensity physical activity were self reported and in a 11.5% (n=90) random subsample of participants, physical activity was objectively measured by an accelerometer. RESULTS: No significant difference was found in rates of smoking abstinence at end of pregnancy between the physical activity and control groups (8% v 6%; odds ratio 1.21, 95% confidence interval 0.70 to 2.10). For the physical activity group compared with the control group, there was a 40% (95% confidence interval 13% to 73%), 34% (6% to 69%), and 46% (12% to 91%) greater increase in self reported minutes carrying out physical activity per week from baseline to one week, four weeks, and six weeks post-quit day, respectively. According to the accelerometer data there was no significant difference in physical activity levels between the groups. Participants attended a median of four treatment sessions in the intervention group and three in the control group. Adverse events and birth outcomes were similar between the two groups, except for significantly more caesarean births in the control group than in the physical activity group (29% v 21%, P=0.023). CONCLUSION: Adding a physical activity intervention to behavioural smoking cessation support for pregnant women did not increase cessation rates at end of pregnancy. During pregnancy, physical activity is not recommended for smoking cessation but remains indicated for general health benefits. Trial registration Current Controlled Trials ISRCTN48600346.

dc.format.extent0-0
dc.format.mediumElectronic
dc.languageen
dc.language.isoen
dc.publisherBMJ
dc.subjectAdolescent
dc.subjectAdult
dc.subjectBehavior Therapy
dc.subjectCombined Modality Therapy
dc.subjectEngland
dc.subjectExercise Therapy
dc.subjectFemale
dc.subjectHealth Behavior
dc.subjectHealth Knowledge, Attitudes, Practice
dc.subjectHumans
dc.subjectInfant, Newborn
dc.subjectIntention
dc.subjectMiddle Aged
dc.subjectMotivation
dc.subjectPatient Compliance
dc.subjectPregnancy
dc.subjectPrenatal Care
dc.subjectSmoking
dc.subjectSmoking Cessation
dc.subjectSmoking Prevention
dc.subjectSocial Support
dc.subjectTreatment Outcome
dc.titlePhysical activity for smoking cessation in pregnancy: randomised controlled trial
dc.typejournal-article
dc.typeJournal Article
dc.typeMulticenter Study
dc.typeRandomized Controlled Trial
dc.typeResearch Support, Non-U.S. Gov't
plymouth.author-urlhttps://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000354770100004&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=11bb513d99f797142bcfeffcc58ea008
plymouth.issue0
plymouth.volume350
plymouth.publication-statusPublished
plymouth.journalBMJ
dc.identifier.doi10.1136/bmj.h2145
plymouth.organisational-group/Plymouth
plymouth.organisational-group/Plymouth/Faculty of Health
plymouth.organisational-group/Plymouth/Faculty of Health/Peninsula Medical School
plymouth.organisational-group/Plymouth/REF 2021 Researchers by UoA
plymouth.organisational-group/Plymouth/REF 2021 Researchers by UoA/UoA03 Allied Health Professions, Dentistry, Nursing and Pharmacy
plymouth.organisational-group/Plymouth/Research Groups
plymouth.organisational-group/Plymouth/Research Groups/FoH - Community and Primary Care
plymouth.organisational-group/Plymouth/Research Groups/Institute of Health and Community
plymouth.organisational-group/Plymouth/Research Groups/Institute of Translational and Stratified Medicine (ITSMED)
plymouth.organisational-group/Plymouth/Research Groups/Institute of Translational and Stratified Medicine (ITSMED)/CCT&PS
plymouth.organisational-group/Plymouth/Research Groups/Plymouth Institute of Health and Care Research (PIHR)
plymouth.organisational-group/Plymouth/Users by role
plymouth.organisational-group/Plymouth/Users by role/Academics
plymouth.organisational-group/Plymouth/Users by role/Researchers in ResearchFish submission
dc.publisher.placeEngland
dcterms.dateAccepted2015-03-23
dc.identifier.eissn1756-1833
dc.rights.embargoperiodNot known
rioxxterms.versionofrecord10.1136/bmj.h2145
rioxxterms.licenseref.urihttp://www.rioxx.net/licenses/all-rights-reserved
rioxxterms.licenseref.startdate2015-05-14
rioxxterms.typeJournal Article/Review


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