Chemotherapy Dosing Part II: Alternative Approaches and Future Prospects
dc.contributor.author | Sewell, GJ | |
dc.contributor.author | Kaestner, S | |
dc.date.accessioned | 2015-10-27T16:26:33Z | |
dc.date.available | 2015-10-27T16:26:33Z | |
dc.date.issued | 2007 | |
dc.identifier.issn | 0936-6555 | |
dc.identifier.issn | 1433-2981 | |
dc.identifier.uri | http://hdl.handle.net/10026.1/3715 | |
dc.description.abstract |
This overview follows on from part I, which described the current practices used in chemotherapy dosing and the paucity of scientific evidence to support them. In part II, alternative approaches are discussed, both in terms of scientific rationale and practical application. These include therapeutic drug monitoring, the use of pharmacokinetic-pharmacodynamic relationships, flat-fixed dosing, Bayesian modelling and dose banding. | |
dc.format.extent | 99-107 | |
dc.format.medium | ||
dc.language | en | |
dc.language.iso | en | |
dc.publisher | Elsevier BV | |
dc.subject | Animals | |
dc.subject | Antineoplastic Agents | |
dc.subject | Carboplatin | |
dc.subject | Dose-Response Relationship, Drug | |
dc.subject | Drug Monitoring | |
dc.subject | Humans | |
dc.subject | Models, Biological | |
dc.subject | Neoplasms | |
dc.title | Chemotherapy Dosing Part II: Alternative Approaches and Future Prospects | |
dc.type | journal-article | |
dc.type | Review | |
plymouth.author-url | https://www.ncbi.nlm.nih.gov/pubmed/17355104 | |
plymouth.issue | 2 | |
plymouth.volume | 19 | |
plymouth.publication-status | Published | |
plymouth.journal | Clinical Oncology | |
dc.identifier.doi | 10.1016/j.clon.2006.10.003 | |
plymouth.organisational-group | /Plymouth | |
plymouth.organisational-group | /Plymouth/Faculty of Health | |
plymouth.organisational-group | /Plymouth/REF 2021 Researchers by UoA | |
plymouth.organisational-group | /Plymouth/REF 2021 Researchers by UoA/UoA03 Allied Health Professions, Dentistry, Nursing and Pharmacy | |
plymouth.organisational-group | /Plymouth/REF 2021 Researchers by UoA/UoA03 Allied Health Professions, Dentistry, Nursing and Pharmacy/UoA03 Allied Health Professions, Dentistry, Nursing and Pharmacy MANUAL | |
plymouth.organisational-group | /Plymouth/Research Groups | |
plymouth.organisational-group | /Plymouth/Research Groups/Institute of Health and Community | |
plymouth.organisational-group | /Plymouth/Users by role | |
dc.publisher.place | England | |
dc.identifier.eissn | 1433-2981 | |
dc.rights.embargoperiod | Not known | |
rioxxterms.versionofrecord | 10.1016/j.clon.2006.10.003 | |
rioxxterms.licenseref.uri | http://www.rioxx.net/licenses/all-rights-reserved | |
rioxxterms.type | Journal Article/Review |