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dc.contributor.authorSewell, GJ
dc.contributor.authorKaestner, S
dc.date.accessioned2015-10-27T16:26:33Z
dc.date.available2015-10-27T16:26:33Z
dc.date.issued2007
dc.identifier.issn0936-6555
dc.identifier.issn1433-2981
dc.identifier.urihttp://hdl.handle.net/10026.1/3715
dc.description.abstract

This overview follows on from part I, which described the current practices used in chemotherapy dosing and the paucity of scientific evidence to support them. In part II, alternative approaches are discussed, both in terms of scientific rationale and practical application. These include therapeutic drug monitoring, the use of pharmacokinetic-pharmacodynamic relationships, flat-fixed dosing, Bayesian modelling and dose banding.

dc.format.extent99-107
dc.format.mediumPrint
dc.languageen
dc.language.isoen
dc.publisherElsevier BV
dc.subjectAnimals
dc.subjectAntineoplastic Agents
dc.subjectCarboplatin
dc.subjectDose-Response Relationship, Drug
dc.subjectDrug Monitoring
dc.subjectHumans
dc.subjectModels, Biological
dc.subjectNeoplasms
dc.titleChemotherapy Dosing Part II: Alternative Approaches and Future Prospects
dc.typejournal-article
dc.typeReview
plymouth.author-urlhttps://www.ncbi.nlm.nih.gov/pubmed/17355104
plymouth.issue2
plymouth.volume19
plymouth.publication-statusPublished
plymouth.journalClinical Oncology
dc.identifier.doi10.1016/j.clon.2006.10.003
plymouth.organisational-group/Plymouth
plymouth.organisational-group/Plymouth/Faculty of Health
plymouth.organisational-group/Plymouth/REF 2021 Researchers by UoA
plymouth.organisational-group/Plymouth/REF 2021 Researchers by UoA/UoA03 Allied Health Professions, Dentistry, Nursing and Pharmacy
plymouth.organisational-group/Plymouth/REF 2021 Researchers by UoA/UoA03 Allied Health Professions, Dentistry, Nursing and Pharmacy/UoA03 Allied Health Professions, Dentistry, Nursing and Pharmacy MANUAL
plymouth.organisational-group/Plymouth/Research Groups
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dc.publisher.placeEngland
dc.identifier.eissn1433-2981
dc.rights.embargoperiodNot known
rioxxterms.versionofrecord10.1016/j.clon.2006.10.003
rioxxterms.licenseref.urihttp://www.rioxx.net/licenses/all-rights-reserved
rioxxterms.typeJournal Article/Review


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