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dc.contributor.authorBrown, SM
dc.contributor.authorSneyd, JR
dc.date.accessioned2015-07-28T12:49:43Z
dc.date.available2015-07-28T12:49:43Z
dc.date.issued2015-06-08
dc.identifier.issn2058-5349
dc.identifier.issn2058-5357
dc.identifier.urihttp://hdl.handle.net/10026.1/3468
dc.description.abstract

Nitrous oxide is an N-methyl--aspartate receptor antagonist and may reduce the incidence of chronic post-surgical pain. • Nitrous oxide oxidizes Vitamin B12 and can precipitate sub-acute combined degeneration of the cord with chronic use or in patients with folate/B12 deficiency. • Nitrous oxide expands air spaces and is contraindicated in patients with pneumothorax or recent (up to 4–6 weeks) ocular surgery using intraocular gas. • Nitrous oxide has global warming and ozone depletion potential and its concentration in the theatre environment is regulated. • The ENIGMA-II trial showed that nitrous oxide does not increase the risk of death or cardiovascular complications.

dc.format.extent1-5
dc.languageen
dc.language.isoen
dc.publisherElsevier BV
dc.subject32 Biomedical and Clinical Sciences
dc.subject3202 Clinical Sciences
dc.titleNitrous oxide in modern anaesthetic practice
dc.typejournal-article
dc.typeArticle
plymouth.issue3
plymouth.volume16
plymouth.publisher-urlhttp://dx.doi.org/10.1093/bjaceaccp/mkv019
plymouth.publication-statusPublished
plymouth.journalBJA Education
dc.identifier.doi10.1093/bjaceaccp/mkv019
plymouth.organisational-group/Plymouth
plymouth.organisational-group/Plymouth/Faculty of Health
plymouth.organisational-group/Plymouth/Users by role
dc.identifier.eissn2058-5357
dc.rights.embargoperiodNot known
rioxxterms.versionofrecord10.1093/bjaceaccp/mkv019
rioxxterms.licenseref.urihttp://www.rioxx.net/licenses/all-rights-reserved
rioxxterms.typeJournal Article/Review


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