Single virus detection on silicon photonic crystal random cavities
dc.contributor.author | Watanabe, K | |
dc.contributor.author | Wu, H-Y | |
dc.contributor.author | Xavier, J | |
dc.contributor.author | joshi, lovleen | |
dc.contributor.author | Vollmer, F | |
dc.date.accessioned | 2022-02-11T13:38:18Z | |
dc.date.issued | 2022-02-26 | |
dc.identifier.issn | 1613-6810 | |
dc.identifier.issn | 1613-6829 | |
dc.identifier.other | ARTN 2107597 | |
dc.identifier.uri | http://hdl.handle.net/10026.1/18750 | |
dc.description.abstract |
<jats:title>Abstract</jats:title><jats:p>On‐chip silicon microcavity sensors are advantageous for the detection of virus and biomolecules due to their compactness and the enhanced light–matter interaction with the analyte. While their theoretical sensitivity is at the single‐molecule level, the fabrication of high quality (<jats:italic>Q</jats:italic>) factor silicon cavities and their integration with optical couplers remain as major hurdles in applications such as single virus detection. Here, label‐free single virus detection using silicon photonic crystal random cavities is proposed and demonstrated. The sensor chips consist of free‐standing silicon photonic crystal waveguides and do not require pre‐fabricated defect cavities or optical couplers. Residual fabrication disorder results in Anderson‐localized cavity modes which are excited by a free space beam. The <jats:italic>Q</jats:italic> ≈10<jats:sup>5</jats:sup> is sufficient for observing discrete step‐changes in resonance wavelength for the binding of single adenoviruses (≈50 nm radius). The authors’ findings point to future applications of CMOS‐compatible silicon sensor chips supporting Anderson‐localized modes that have detection capabilities at the level of single nanoparticles and molecules.</jats:p> | |
dc.format.extent | e2107597- | |
dc.format.medium | Print-Electronic | |
dc.language | en | |
dc.language.iso | en | |
dc.publisher | Wiley | |
dc.subject | Anderson localization | |
dc.subject | biosensors | |
dc.subject | photonic crystals | |
dc.subject | silicon photonics | |
dc.subject | viruses | |
dc.title | Single virus detection on silicon photonic crystal random cavities | |
dc.type | journal-article | |
dc.type | Journal Article | |
dc.type | Research Support, Non-U.S. Gov't | |
plymouth.author-url | https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000761246600001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=11bb513d99f797142bcfeffcc58ea008 | |
plymouth.issue | 15 | |
plymouth.volume | 18 | |
plymouth.publication-status | Published | |
plymouth.journal | Small | |
dc.identifier.doi | 10.1002/smll.202107597 | |
plymouth.organisational-group | /Plymouth | |
plymouth.organisational-group | /Plymouth/Faculty of Health | |
plymouth.organisational-group | /Plymouth/Faculty of Health/School of Biomedical Sciences | |
plymouth.organisational-group | /Plymouth/REF 2021 Researchers by UoA | |
plymouth.organisational-group | /Plymouth/REF 2021 Researchers by UoA/UoA01 Clinical Medicine | |
plymouth.organisational-group | /Plymouth/Users by role | |
plymouth.organisational-group | /Plymouth/Users by role/Academics | |
dc.publisher.place | Germany | |
dcterms.dateAccepted | 2022-02-04 | |
dc.rights.embargodate | 2022-3-1 | |
dc.identifier.eissn | 1613-6829 | |
dc.rights.embargoperiod | Not known | |
rioxxterms.versionofrecord | 10.1002/smll.202107597 | |
rioxxterms.licenseref.uri | http://www.rioxx.net/licenses/all-rights-reserved | |
rioxxterms.licenseref.startdate | 2022-02-26 | |
rioxxterms.type | Journal Article/Review |